• Journal of Chest Surgery
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• 제24권6호
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• pp.533-540
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• 1991

We have performed 14 single lung transplantation in mongrel dogs transplanting the left lung exclusively from December 1989 to January 1991, in the department of thoracic surgery of Seoul National University Hospital. In the donor dogs, the main pulmonary artery was divided proximal to its bifurcation, and the left atrium was incised freeing the left veins with a generous atrial cuff. We used cold saline in the first 7 transplantation[group I ] and a Euro Collins solution in the remaining 7 transplantations[group II ] as a lung preservatives. The bronchus was divided at two cartilage rings proximal to the upper lobe bronchus take off. In the recipient procedure, we used a Fogarty catheter as a bronchus block. Left atrial anastomosis was performed first using 5 - 0 prolene and the pulmonary artery was anastomosed using 6 - 0 prolene. The bronchus was anastomosed next with 4 - 0 Vicryl interruptly and covered with a greater omentum which had been prepared previously. In group I the three dogs died at eleven hours, 5 days, and 14 days, postoperatively and the remaining four doings were killed at 5 days, 5 days, 6 days, and 12 days, respectively. In group II the two dogs died during the operation, one dog died at 6 hours, two dogs died at 6 days postoperatively. Two dogs were killed at 5 days, and 7 days. No significant difference was noted between the two groups in survival time, lung infiltration of transplanted lungs, and perfusion defects in perfusion lung scans. Of the 8 dogs which died naturally, the causes of death were as follows: 2 cases of sepsis, 2 cases of ventricular fibrillations, 2 cases of malnutrition, and 2 cases of respiratory failures.

• Journal of Chest Surgery
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• 제25권3호
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• pp.220-231
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• 1992

We have performed 28 single lung transplantation in mongrel dogs transplanting the left lung exclusively from November 1989 to September 1991, in the department of thoracic surgery of Seoul National University Hospital. In the donor dogs, the main pulmonary artery was divided proximal to its bifurcation, and the left atrium was incised freeing the left veins with a generous atrial cuff. We used cold saline in the first 7 transplantations and Euro-Collins or modified Euro-Collins solution in the remaining 17 transplantations as a lung preservatives. The bronchus was divided at two cartilage rings proximal to the upper lobe bronchus take off. In the recipient procedure, we used a Fogarty catheter as a bronchus block. Left atrial anastomosis was performed first using 5-O prolene and the pulmonary artery was anastomosed using 6-O prolene. The bronchus was anastomosed next with 4-O vicryl interruptedly and covered with a greater omentum which had been prepared previously. All dogs received cyclosporin A and azathioprine as immunosuppressants and were divided into two group. In the 10 Group I dogs, they survived within 6 days, mean survival time was 66.8$\pm$53.4 hours. In remainder 14 Group lI dogs, they survived above 6 days, mean survival time was 9. 5$\pm$5.6 days. The cause of death were as follows: 2 cases of sacrifice, 2 cases of respiratory insufficiency during operation, 2 cases of arrhythmia immediate postoperatively, 2 cases of bleeding, others in Group I, and 6 cases of sacrifice, 4 cases of sepsis, 3 cases of bleeding, others in Group lI. Results of bronchoscopic findings were obstruction above 50% in 12 cases of 16 performance cases within 5th day. Early chest radiologic haziness were showed, and total lung perfusion defect was frequently showed in both group within 7th day. Main autopsy findings were left atrial and pulmonary arterial thrombi and bronchial obstruction The major histologic findings of Group I were pleural exudate, hemorrhagic infarct, pulmonary congestion, and interesting histologic findings of Group II were 3 cases of perivascular or peribronchial lymphocyte infiltration, 3 cases of hemorrhage infarct, 2 cases of interstitial pneumonitis. The structual change of bronchioles, suggesting bronchiolitis obliterans was not observed due to improper preparation of proximal pulmonary tissue and short term survival times.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1982년도 제16차 학술대회연제순서 및 초록
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• pp.8.1-8
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• 1982

기도 이물은 이비인후와 영역에서 중요한 위치를 차지하고 있는 질환으로서, 타 질환에 비하여 그리 드문 것은 아니며 지금까지 국내외에서 많은 보고가 있어왔다. 기도 이물은 때로는 순식간에 생명을 위협하거나 중증의 합병증을 초래하기도 하며, 이물의 종류와 형태도 다양할 뿐 아니라 그 개재부위도 달라서 이물적출은 항상 낙관을 불허하는 것으로 수술적 방법을 요할때도 있다. 저자들은 최근에, 이물이 자연 객출된 1예와 기관지경술로 성공한 4예 및 외과적 수술로 제거한 2 예를 경험하였기에 문헌적 고찰과 함께 보고하는 바이다.

• 대한한의학방제학회지
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• 제9권1호
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• pp.273-288
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• 2001

Objectives : In order to study the effect of oral administration of Jungcheonhwadamgangki-tang against the asthma. Method : Asthma was induced to Balb/c mouse with ovalbumin by using method of Hatfield et al. It was observed the changes numbers and morphology of the mast cells in the trachea, numbers of mucous secretory cell in the bronchus, morphology of the bronchus, ultramicroscopical appearance of surface of trachea and number of cilia and mucous secretory cells by scanning electron microscope. Result : 1. Degranulation and decreasing of the numbers of mast cells were significantly decreased in the Jungcheonhwadamgangki-tang extract group as compared with control group. 2. Hypertrophy of mucous membrane of bronchus In the lung, infiltration of inflammatory cells, increasing of mucous secretory cells in the bronchus were significantly decreased in the Jungcheonhwadamgangki-tang extract group as compared with control group. 3. Shedding, decreasing of cilia cells and increasing of mucous secretory cells in the surface of the trachea were significantly decreased in the Jungcheonhwadamgangki-tang extract group as compared with control group. Conclusion : It is considered that Jungcheonhwadamgangki-tang has somewhat favorable effects on the asthma because the asthma specific series of abnormalities in respiratory system were decreased after oral administration of Jungcheonhwadamgangki-tang in this study. In future, it is needed that the toxicological and dosage specific study of Jungcheonwhadamgangki-tang to use against bronchial asthma with safe.

• Journal of Chest Surgery
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• 제39권3호
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• pp.244-247
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• 2006

과립 세포종은 흔치않은 양성 종양으로 주로 피부, 혀, 유방에 생기는 것으로 알려져 있다. 이 종양은 각기 다른 장기에 동시 다발적으로도 생길 수 있으며, 한 장기에 여러 군데 생기기도 하는 것으로 알려져 있다. 기관지 계통에서의 빈도는 잘 알려져 있지 않으며, 폐에 발생할 확률은 현재까지 보고된 증례가 약 100예에 지나지 않을 정도로 드문 질환으로 알려져 있다. 폐렴증상을 주소로 33세의 남자환자가 내원 후 기관지 내시경 검사에서 기관지 내 종양이 발견되어 실시한 조직검사상 과립 세포종으로 확인되었다. 환자는 좌측 주 기관지 절개 후 종양 적출술을 받은 다음 기관지 단-단 봉합술을 받았다. 퇴원 후 현재까지 특별한 재발의 징후 없이 1년째 외래 추적 관찰 중이다.

• 대한한의학회지
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• 제23권3호
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• pp.104-118
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• 2002

Objectives : To study the effects of Kumsooyukkun-jeon on asthma. Methods : Asthma was induced to Balb/c mice with ovalbumin using the method of Hatfield et al. We measured the histological profiles of lung and trachea, numbers of cellular compartments in the bronchoalveolar lavage fluid (BALF), numbers and morphology of the mast cells in the trachea, numbers of mucous-secretory cells in the bronchus, morphology of the bronchus, ultramicroscopical appearance of surface of trachea and number of cilia and mucous-secretory cells by scanning electron microscope. Results : 1. Hypertrophy of mucous membrane of trachea and bronchus and bronchioles in the lung, peritracheal, peribronchus and peribronchiolar inflammatory cell infiltration, and mucoid exudate deposition the lumen were observed in control groups but these phenomena were recovered in the Kumsooyukkun-jeon groups. 2. Cellular compartments including neutrophil and eosinophil were increased in the BALF of control groups but these phenomena were recovered in the Kumsooyukkun-jeon groups. 3. Degranulation and decrease of the numbers of mast cells were detected in the trachea of control groups. However, these phenomena were recovered in the Kumsooyukkun-jeon groups. 4. Shedding, decrease of cilia cell and increase of mucous-secretory cells in the surface of the trachea were measured in control groups but these phenomena were recovered in the Kumsooyukkun-jeon groups. Conclusions : It is considered that Kumsooyukkun-jeon has somewhat favorable effects on asthma.

• Journal of Chest Surgery
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• 제18권3호
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• pp.497-505
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• 1985

Bronchoplastic techniques represent the ideal surgical therapy for benign endobronchial tumors as well as tumors of low-grade malignant potential, such as bronchial adenomas, and for repair of traumatic airway injuries and benign strictures. This approach is also applicable to a select group of patients with carcinoma of the lung, with long-term survival being comparable to that achieved by standard pneumonectomy. Five bronchoplastic procedures were performed at Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital during 7 months periods from Dec. 1984 to Jun. 1985. Of the 5 patients, 3 patients were male and 2 patients were female and ages ranged from 8 years to 55 years old. The final diagnoses of 5 patients were as followed; traumatic bronchostenosis, endobronchial tuberculoma, carcinoid tumor, tuberculous bronchostenosis and traumatic bronchial fracture. Operative procedures of 5 patients were as followed; resection and end-to-end anastomosis of right main bronchus, left lower lobectomy and wedge resection of bronchus, left upper sleeve lobectomy, right middle and lower sleeve lobectomy and resection and end-to-end anastomosis of left main bronchus. And 2 lungs and 3 lobes could be preserved by these bronchoplastic procedures. There was no post-operative complication or mortality and all patients are being followed up without specific problem.

• Journal of Trauma and Injury
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• 제24권1호
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• pp.7-11
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• 2011

Purpose: Traumatic airway injuries have high rates of mortality and morbidity. Thus, we evaluated the clinical results of trauma-related airway-injury patients. Methods: A clinical analysis was performed for patients with airway trauma who were admitted and treated at the Department of Thoracic and Cardiovascular Surgery, Konyang University Hospital from Dec. 2002 to Dec. 2009. Results: Sixteen patients were admitted and treated. Fourteen patients were male, and the ages of the patients ranged from 16 to 75 years. Six cases were penetrating injuries, 4 were traffic-accident injuries. 3 were fall injuries, and. 3 were other blunt trauma injuries. Anato- mic injuries included 14 trachea cases (87.5%), 1 Rt. main bronchus (6.25%), and 1 Lt. main bronchus cases (6.25%). Diagnosis was made by using computed tomography and bronchoscopy. Five patients were treated with an explothoracotomy, and 7 underwent neck exploration with primary repair. Three patients simply needed conservative management, and 1 patient was treated with a closed thoracostomy. The post-operative mortality rate was 6.25 % (1 patient). Conclusion: Airway trauma is dangerous and should be treated as an emergency, so a high index of suspicion is essential for rapid diagnosis and successful surgical intervention in patients with airway injuries.

• Journal of Chest Surgery
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• 제39권8호
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• pp.648-651
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• 2006

53세 여자가 내원 4일 전부터 심해지는 객혈을 주소로 내원하였다. 흉부 X-선상 우상엽에 고립성 폐결절이 보였고, 흉부 컴퓨터 단층 촬영상 우상엽 후분절 기관지를 막고 있는 결절을 보였다. 기관지 내시경적 검사로 우상엽 후분절 기관지를 완전히 막고 있는 부스러지기 쉬운 황색과 갈색의 진흙 같은 덩어리가 보였고 생검 병리학적 검사로 국균종으로 진단되었다. 환자는 지속되는 객혈로 인해 우상엽 및 우중엽 절제술을 시행하였다. 기관-기관지 국균증은 면역기능이 정상인의 경우에는 아주 드물게 나타나는 형태의 국균증이기에 우리나라 문헌에서 보고된 기관지 내 국균증의 고찰과 함께 비교하여 본 증례를 보고하는 바이다.

• 한국멀티미디어학회논문지
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• 제14권11호
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• pp.1383-1391
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• 2011

향상된 기능을 가진 최신 의료장비들의 등장으로 하드웨어 성능에 부합하는 효과적인 영상처리 및 분석의 중요성이 부각되고 있으며, 2차원 의료 영상처리 및 3차원 영상 재구성에 관한 많은 연구들이 진행되고 있다. 본 논문은 흉부 CT 영상을 사용하여 신체 장기를 단계별로 분할 하였으며, 분할된 결과 영상을 3차원으로 재구성 하였다. 다양한 영상분할 방법중 영역 확장법 및 효과적인 분할을 위해 선명화와 감마 조절등과 같은 영상 향상 기법을 적용하였으며, 기관지를 포함한 폐, 기관지, 폐 등의 순서로 영상을 분할하였다. 분할된 신체 장기 영상을 VTK를 사용하여 3차원 영상으로 재구성 하였으며, 병변 진단을 위한 2차원 및 3차원 의료 영상 처리와 분석에 활용될 것으로 판단된다.