• Neonatal Medicine
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• 제25권3호
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• pp.109-117
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• 2018

Purpose: Minimally invasive surfactant therapy (MIST) is currently used as a method of surfactant replacement therapy (SRT) for the treatment of respiratory distress syndrome (RDS) in preterm infants with a gestational age of less than 30 weeks. However, few studies have been conducted on MIST in neonates with a gestational age of 30 weeks or more. In this study, we compared MIST with endotracheal intubation as a rescue SRT for spontaneously breathing neonates with a gestational age of 30 weeks or more who were diagnosed with RDS. Methods: We investigated the clinical characteristics of spontaneously breathing neonates admitted to the neonatal intensive care unit of the Inje University Sanggye Paik Hospital from January 1, 2014 to December 31, 2016. These neonates were born at a gestational age of 30 weeks or more and were diagnosed with RDS. The neonates who were administered surfactant by MIST were categorized into the MIST group (n=16) and those who underwent endotracheal intubation were categorized into the control group (n=45). Thereafter, the clinical characteristics between the groups were compared. Results: Compared to the control group, the MIST group was less likely to require mechanical ventilation within 72 hours (P<0.001). The frequency of bradycardia during SRT was also low in the MIST group (P=0.033). Conclusion: MIST is considered relatively feasible and safe for treating RDS for reducing the need for mechanical ventilation and decreasing the occurrence of bradycardia during surfactant administration in neonates with a gestational age of 30 weeks or more.

• 한국산학기술학회논문지
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• 제19권9호
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• pp.139-145
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• 2018

일반인이 심정지를 신속하게 인지하는 것은 심정지 생존에 중요한 첫 단계이다. 본 연구는 심정지 상황에서 발생하는 심정지 호흡을 기존 강의식 교육과 동영상 교육으로 시행한 후, 심정지 인지를 분석하여 효과적인 교육방법을 파악하고자 연구를 수행하였다. 연구설계는 연구대상자를 강의식 교육과 동영상 교육으로 무작위로 배정하여 교육을 수행한 후 심정지인지를 비교한 무작위 대조군 연구이다. 연구기간은 2015년 10월 30일부터 10월 31일까지 시행하였으며, 연구대상은 15세 이상 청소년 104명으로 실험군 52명, 대조군 52명으로 선정하였다. 연구결과, 반응이 없고 호흡이 없는 동영상에서 실험군과 대조군의 차이를 보이지 않았다(p=0.741). 하지만 반응이 없고 심정지 호흡을 보이는 동영상에서는 실험군 중 심폐소생술시행이 43명(82.7%), 대조군 중 심폐소생술 시행이 33명(63.5%)으로 유의한 차이를 나타냈다(p=0.006). 이러한 결과를 통하여 심폐소생술 교육 시 동영상으로 심정지 호흡을 교육하는 것이 기존 강의식 교육에 비해 심정지 인지를 향상시키는 것을 파악할 수 있었다.

• 한국융합학회논문지
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• 제11권9호
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• pp.51-57
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• 2020

본 연구는 칼텐본을 접목한 흉추가동운동이 폐기능에 미치는 영향을 알아보기 위하여 20대 대학생 20명을 대상으로 4주간 실시하였다. 실험대상자 20명을 대상으로 실험군, 대조군으로 무작위 동공선택방식으로 그룹 배정을 하였다. 실험군은 횡격막 호흡운동 15분과 칼텐본을 적용한 흉추가동운동 15분으로 구성되고, 대조군은 횡격막 호흡운동으로 30분간 훈련하였으며, 두 군의 운동프로그램은 주 3회 4주간 실시하였다. 측정은 폐기능을 측정하여 자료를 분석하였다. 실험 전·후 폐기능을 분석해 보면, 실험군은 TV, IRV에서 유의하게 증가하였으며, 실험후에 두 집단간의 변화검증에서도 TV와 IRV에서 유의한 차이가 나타났다. 본 연구를 통해 칼텐본을 이용한 흉추가동운동이 폐 기능에 더 긍정적인 효과를 주는 것을 알 수 있었다. 앞으로 임상에서 호흡훈련 시 일반적인 호흡훈련에 흉추가동운동을 함께 접목하는 치료방법이 적극적으로 중재되기를 기대하며 다양한 추가운동프로그램의 개발이 필요할 것으로 사료된다.

• 대한수의학회지
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• 제4권1호
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• pp.27-33
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• 1964

In the treatment of mice Aureomycin, Oil penicillin, Achromycin, Ambrasynth and Terramycin were effective on the Black-leg disease when they were administered about 4 to 5 hours before the death of control animals. Synthomycetin, however, was observed to be effective when administered 8 hours or more before the control death. Streptomycin seemed to be rather less effective than Black leg antiserum. It was not effective at all when given 19 hours before the death of control animal although there was a delay of taking death by 5 hours in the treated group. As was in mice, Streptomycin was little effective in the treatment of calves, while other antibiotics showed fine efficacy on the diseased animals. The diseased animals, when given with anitibiotics 37 hours before the death of control showed the rise of temperature($41^{\circ}C$ or more), swelling and redness on the site of infection and then recovcred to normal stage. In the treatment of calves, Aureomycin only delayed the taking death of the deseased animals by 111 hours when administered 4 hours before the death of control animals. And other antibiotics, when given 4 hours before the death of control animals were effective, although the deseased animls developed symptoms such as hard breathing, anorexia and dropsical swellings. Oil penicillin was observed to be comparatively larger in its efficacy on the treatment of Black leg disease.

• 대한임상전기생리학회지
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• 제4권1호
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• pp.39-47
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• 2006

Functional Electrical Stimulation(FES) cause paralysed muscles to contract in some clinical circumstances. Generally, FES has been thought of as a valuable tool in activating any skeletal muscle paralysed as a result of upper motor neuron damage. But, the function of cardiac and smooth muscle is also affected by upper motor neuron damage. Today, various applications of FES are investigated, including conditioning cardiovascular exercise, caugh and breathing assistant, improving bowel and bladder control, hand grasp, standing and walking etc. This review will focus on the literature reporting application of FES to control respiratory capabilities and internal organ function as well as increase muscular strength, hand grasp, standing and walking in patients with upper motor diseases.

• 수면정신생리
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• 제12권2호
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• pp.105-110
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• 2005

The pathogenesis and mechanism of obstructive sleep apnea (OSA) has been under investigation for over 25 years, but its etiology and mechanism remains elusive. Skeletal (maxillary and/or mandibular hypoplasia or retrodisplacement, inferior displacement of hyoid) and soft tissue (increased volume of soft tissue, adenotonsillar hypertrophy, macroglossia, thickened lateral pharyngeal walls) factors, pharyngeal compliance (increased), pharyngeal muscle factors (impaired strength and endurance of pharyngeal dilators and fixators), sensory factors (impaired mechanoreceptor sensitivity, impaired pharyngeal dilator reflexes), respiratory control system factors (unstable respiratory control) and so on facilitate collapse upper airway. Therefore, OSA may be a heterogeneous disorder, rather than a single disease entity and various pathogenic factors contribute to the OSA varies person to person. As a result, patients may respond to different therapeutic approaches based on the predominant abnormality leading to the sleep-disordered breathing.

• 대한간호학회지
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• 제36권8호
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• pp.1367-1373
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• 2006

Purpose. This study was designed to examine the effects of a bereavement intervention program on levels of depression and life satisfaction in middle aged widows in Korea. Methods. A quasi-experimental design with non-equivalent control-group pretest-posttest was used. The subjects (control group, n = 10; intervention group, n = 17) were bereaved less than 6 months in G City and J Province, Korea. The bereavement intervention program consisted of Dan-jeon breathing, self-help group activities and a health examination. The experimental group attended 10 sessions of a bereavement intervention program. The control group had a health examination without the intervention program. For both groups, the level of depression and life satisfaction levels were measured before and after the experiment. Results. The decrement of depression level in the experimental group was significantly greater than in the control group (p <.001). The increment in life satisfaction in the experimental group was significantly greater than in the control group (p <.001). Conclusion. The results suggested that the bereavement intervention program was effective in decreasing level of depression and in increasing the life satisfaction of widows. Accordingly, a bereavement intervention program can be applied as an intervention to help widows.

• 수면정신생리
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• 제3권2호
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• pp.32-42
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• 1996

연구배경 : 상기도 저항증후군 (UARS)으로 진단 받은 환자 및 이들의 수면다원검사 소견을 정상인 및 수면 무호흡증(OSA) 환자의 그것과 비교 연구함으로서 UARS의 이해에 도움을 얻고자하였다. 방법 : 임상적인 면담, 신체검사 및 식도내 음압 (Pes)의 측정을 포함하는 수면다원검사를 통하여 UARS로 진단받은 20 명의 환자와 OSA로 진단 받은 30명의 환자를 대상으로 하였고, Williams 등 (10)의 자료를 정상비교치로 이용하였다. 결과 : UARS는 OSA 보다 젊고 비만도가 낮은 환자특성을 보이고 수면다원검사시 OSA의 진단기준이 되는 RDI와 $SaO_2$가 정상에 가까운 특정을 보임을 알 수 있다. 기타 수면지표들은 정상범위에 속하거나 이상소견이 있더라도 OSA 환자의 그것보다는 경미하여 UARS가 OSA보다는 가벼운 상태의 장애임을 시사한다. 그러나 UARS 환자들의 ESS의 점수는 병적인 수준으로 낮 동안의 졸림기로 일상생활에 많은 장애를 받고 있음을 시사한다. 결론 : 본 연구결과는 UARS 환자의 특성 및 이들의 특정 적인 수면다원검사 소견을 보여줬다고 생각하며 지금까지 발표되고있는 UARS에 대한연구결과들을 지지한다. 즉 UARS는 임상적, 실험실적으로 OSA와는 다른특징이 있는 수면관련 호흡장애의 아형이다. 따라서 임상적으로 수면관련 호흡장애가 의심되는 환자의 나이가 젊고 BMI가 정상이고, 일반수면다원검사에서 RDI와 $SaO_2$ 등이 수면관련 호흡장애 진단기준에 미흡하더라도 수면중 코를 고는 등의 상기도 저항(upper airway resistance)을 시사하는 증상이 있고, 뇌파상 이유없이 자주 반복되는 전기 생리적인 각성이 있다면 UARS를 의심하여야한다. UARS 환자들이 호소하는 낮 동안의 졸림기는 OSA 환자들의 그것과 비슷하여 일상생활에 많은 고통을 주고 반복적인 흉곽내 압력의 지나친 상승은 심혈관계에 해로운 영향을 미치는 바 UARS에 대한관심이 필요하다.

• 대한간호학회지
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• 제38권2호
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• pp.217-228
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• 2008

Purpose: This study was conducted to develop and to determine the effects of an integrated symptom management program for prevention of recurrent cardiac events after percutaneous coronary intervention. Methods: Subjects consisted of 58 CAD patients (experimental group: 30, control group: 28). The experimental group participated in an integrated symptom management program for 6 months which was composed of tailored education, stress management, exercise, diet, deep breathing, music therapy, periodical telephone monitoring and a daily log. The control group received the usual care. Results: The experimental group significantly decreased symptom experiences and the level of LDL compared to the control group. The experimental group significantly increased self care activity and quality of life compared to the control group. Although no significant difference was found in cardiac recurrence, the experimental group had fewer recurrences. Conclusion: These results suggest that an integrated symptom management program for prevention of recurrent cardiac events after percutaneous coronary intervention can improve symptom aggravation, recurrent rate, self care activity and quality of life. Nursing interventions are needed to maintain and further enhance the quality of life of these patients and the interventions should be implemented in the overall transition period.

• Transactions on Control, Automation and Systems Engineering
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• 제2권1호
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• pp.24-30
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• 2000

The aim of this paper is to describe an advanced method of the fault diagnosis using Control Theory with reference to a crack detection, a new way to localize the crack position under influence of the plant disturbance and white measurement noise on a rotating shaft. As the first step, the shaft is physically modelled with a finite element method as usual and the dynamic mathematical model is derived from it using the Hamilton-principle and in this way the system is modelled by various subsystems. The equations of motions with a crack are established by the adaption of the local stiffness change through breathing and gaping[1] from the crack to the equation of motion with an undamaged shaft. This is supposed to be regarded as a reference system for the given system. Based on the fictitious model of the time behaviour induced from vibration phenomena measured at the bearings, a nonlinear state observer is designed in order to detect the crack on the shaft. This is the elementary NL-observer(EOB). Using the elementary observer, an Estimator(Observer Bank) is established and arranged at the certain position on the shaft. In case, a crack is found and its position is known, the procedure, fro the estimation of the depth is going to begin.