• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1797-1802
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• 2013

Background: The aim of this study was to assess clinical factors associated with Helicobacter pylori positivity and to evaluate the incidence of gastric carcinoma in first-degree family members of infected patients. A total of 580 patients (mean age:$38{\pm}17$) with gastrointestinal complaints underwent C-14 urea breath test (UBT). Patients were grouped as: Group-1, untreated patients (n:384); and Group-2, patients who previously treated with eradication triple therapy (n:196). C-14 UBT was performed 1-2 months after the completion of eradication therapy. Associations of H pylori positivity with age, gender, ABO and Rhesus groups, smoking, dietary habits, and history of gastric cancer in first-degree family members were evaluated. The frequency of H pylori positivity was significantly higher in group-1 (58%) compared to group-2 (20%), p=0.001. There were no correlations between H pylori positivity and age, gender, ABO groups, Rhesus subgroups, smoking and dietary habits in both patient groups. The frequency of gastric cancer in family members was significantly higher in patients with H pylori infection among group-1, compared to infected patients among group-2 (56% vs. 28.6% respectively, p=0.03). We observed a significant association between H pylori positivity and the presence of gastric cancer in first-degree relatives of group-1 patients. Our results provide some confirmation of the presence of a link between gastric cancer development and H pylori. C-14 UBT is a sensitive, reliable and a widely recommended test for the detection of H pylori infection and recurrence. We suggest that detection and eradication of H pylori may contribute to a reduced risk of gastric cancer in the family members of infected patients.

• Archives of Pharmacal Research
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• v.29 no.10
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• pp.879-883
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• 2006

To develop a $^{13}C-urea-containing$ capsule for more economic and sensitive diagnosis of Helicobacter pylori infection, the $^{13}C-urea-containing$ capsules were prepared with various additives such as polyethylene glycol, microcrystalline cellulose, sodium lauryl sulfate and citric acid. Their dissolution test and $^{13}C-urea$ Breath Test in human volunteers were then performed. Polyethylene glycol increased the initial dissolution rates of urea and difference ${\sigma}$ $^{13}C$ values from $^{13}C-urea$, while microcrystalline cellulose and sodium lauryl sulfate decreased them. Irrespective of addition of citric acid, the compositions with polyethylene glycol showed higher values from $^{13}C-urea$ compared to a commercial 76 mg $^{13}C-urea-containing$ capsule due to higher initial dissolution rate. The capsules with 38 mg $^{13}C-urea$ and 1.9 mg polyethylene glycol, which showed higher Helicobacter pylori-positive value of about $8{\textperthousand}$ at 10 min, improved the sensitivity of $^{13}C-urea$ in human volunteers. Thus, the $^{13}C-urea-containing$ capsule with polyethylene glycol would be a more economical and sensitive preparation for diagnosis of Helicobacter pylori infection.

• Journal of the Korea Convergence Society
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• v.11 no.10
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• pp.387-392
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• 2020

This study was to investigate the relationship of BMI, sleep time and experience of oral diseases in adolescents. We want to help develop basic data for improving oral health of adolescents. According to the sample design of the Youth Health Behavior online survey, a total of 57,303 adolescents were analyzed for frequency of composite samples, x2-test of composite samples, and logistic regression of composite samples, and the IBM SPSS Statistics 20.0 program was used and the significance level was 0.05. Results, BMI was associated with bad breath, and sleep time was associated with tooth break, pain, bleeding, and bad breath. Therefore, BMI and sleep time should be considered for the management and prevention of oral diseases in adolescents.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.51 no.3
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• pp.122-128
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• 2002

In this paper, a robust pattern classification of breath sounds for the diagnosis of pulmonary dysfunction in noise environment is proposed. The feature parameter extraction method by highpass lifter algorithm and PM(projection measure) algorithm are used. 17 different groups of breath sounds are experimentally classified and investigated. The classification has been performed by 6 different types of combinations with proposed methods to evaluate the performances, such as ARC with EDM and LCC with EDM, WLCC with EDM, ARC with PM, LCC with PM, WLCC with PM. Furthermore, all feature parameters are extracted to 80th orders by 5th orders step, and all experiments are evaluated in increasing noise environments by degrees SNR 24dB to 0dB. As a results, WLCC which is derived from highpass lifter algorithm, is selected for the feature parameter extraction method. Pm is more robust than EDM in noisy environments to test and compare experimental results. WLCC with PM method(WLCC/PM) has a better performance in an increasing noise environment for diagnosis of pulmonary dysfunction.

• Journal of the Society of Naval Architects of Korea
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• v.34 no.1
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• pp.24-40
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• 1997

Horseshoe vortices generated around the juncture between the ship and her appendages often lower a performance of the ship by increasing the appendage drag and making a non-uniform wake on the propeller plane. This paper investigates numerically how the fillet around the juncture of the leading edge influences the juncture flow and the appendage drag. Computation has been made by solving Navier-Stokes equations with MAC method and the flows are at the Reynolds number of 5,000. Five fillets with different height-breath ratios and curvatures are chosen as test models to find out the effects of the shape of fillets on the appendage drag and wake. Computational results show that fillets with a smaller height-breath ratio and/or with a concave curvature has smaller appendage drag and more uniform wake.

• Journal of Sasang Constitutional Medicine
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• v.20 no.3
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• pp.184-189
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• 2008

1. Objectives Pneumothorax is defined as the presence of air or gas in the pleural cavity causing chest pain and shortness of breath. Primary spontaneous pneumothoraces (PSPs) occur in people without underlying lung disease or trauma to the thorax. We have tried researching effect of herbal medicine Doksampalmulkeunja-rang(獨蔘八物君子湯) in PSPs. 2. Methods This patient with PSPs which size was more than 30% of Rt. lung, who had been experienced the recurrences of PSPs in Lt. lung for three times, was treated by Doksampalmulkeunja-tang(獨蔘八物君子湯) diagnosed by Soeumin. 3. Results Doksampalmulkeunja-tang(獨蔘八物君子湯) was effective against the chest discomfort and shortness of breath. The chest test was improved. 4. Conclusions The treatment with herb-medicine may have effect on PSPs symptom of Soeumin by raising the stagnant yang qi. Further Sasang medical study on PSPs is needed for recurrence prevention.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.280.2-280.2
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• 2003

The applicability of liquid chromatography-atmospheric-pressure chemical-ionization mass spectrometry (LC-APCI-MS) for the determination of 13C-urea in 13C-urea/PEG capsules has been studied. It is essential to assess the stability of a newly developed low-dose (38 mg) 13C-urea/PEG capsule. which will be used for 13C-urea breath test (13C-UBT) to detect Helicobacter pylori infection. (omitted)

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.30 no.2
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• pp.95-100
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• 2019

Background and Objectives For patients with polyps and cysts, glottal gaps resulting from their lesions have negative respiratory effects when they vocalize. Phonatory Aerodynamic System is clinically used, but is often limited in the measurement of vowels. So the researchers attempted to verify the usefulness of Phonatory Aerodynamic System by comparing differences in respiratory characteristics and patterns which can be measured by the level of connected speech. Materials and Method Among the subjects who were diagnosed through a stroboscopy, there were 33 patients with polyps and 23 patients with cysts. Then, 36 subjects who were found to have no specific findings through a stroboscopy and perceptual test were selected to the normal group. We compared respiratory characteristics and patterns. And compared vocal polyps and cysts before and after laryngeal micro surgery (LMS). Results First, difference in respiratory patterns between the normal group and the patients with polyps and cysts were examined to show that breath groups, breath group syllables, and expiratory·inspiratory volume were significantly higher in the polyp/cyst group than those in the normal group, indicating that precision was lowered during the conversation, due to reduction in speech intelligibility and interruption of communication. Second, there were significant differences in maximum phonation time, mean flow rate, and subglottal pressure among respiratory characteristics, breath groups, breath group syllables, and inspiratory volume before and after LMS, which appeared to be similar to the normal group. Conclusion The understanding of respiratory characteristics and patterns produced by patients in connected speech which is most similar to natural speech was found to be the objective and useful method for examining characteristics of the subjects.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.2
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• pp.153-158
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• 2016

Purpose: This study was aimed to investigate effects of breath alcohol concentration (BrAC) increase on visual field and readable visual field. Methods: 23 males in 20s (average age $21.17{\pm}2.19years$, body mass index (BMI) $22.09{\pm}2.16$) were selected and administered the amount of alcohol to reach 0.05% and 0.08% BrAC calculated by BAC (blood alcohol concentration) Dosing Software program. Then, visual field and readable visual field test with Vision Disk were conducted. Results: Visual field are measured as $74.41{\pm}15.97^{\circ}$, $64.98{\pm}17.93^{\circ}$, and $58.33{\pm}19.01^{\circ}$ (p=0.000) and readable visual field as $21.93{\pm}12.71^{\circ}$, $17.41{\pm}11.36^{\circ}$, $14.26{\pm}9.93^{\circ}$ (p=0.006) in 0.00%, 0.05% and 0.08% BrAC respectively. As breath alcohol concentration increased, both visual field and readable visual field decreased. Conclusions: BrAC increase with drinking could be the cause of safety accident by decreasing visual field and readable visual field, it is necessary to raise awareness.

• Journal of Veterinary Clinics
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• v.14 no.1
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• pp.37-41
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• 1997

For the inspection of the occurrence situation of porcine pleuropneumonia and serotyping of Actinobacillus pleuropneumoniae strains isolated from lung lesions of pig in Korea, a series of experimentation have been carried out by the isolation and identification of A pleuropneumoniae, serotyping by coagglutination test, observation of lung lesion and clinical signs from 360 cases of porcine pneumonia in Clinical Pathology Laboratory, Bayer Veterinary Medical Research Institute. The results could be summarized as follows. The reaction of coagglutination between the reference antigens and the specific reagents of A pleuropneumoniae was strongly agglutinatied within 30 seconds without cross reaction. The 89 strains of A pleuropneumoniae were isolated from 360 cases of porcine pleuropneumonis and the biochemical properties of the isolates were same as the reference strains. The 89 isolated strains could be serotyped 39 strains as setotype 5, 34 strains as serotype 2, 8 strains as serotype 3, 2 strains as serotype 7 by coagglutination test, respectively. The clinical signs of pleuropneumonia were weakness, fever, anorexia, dyspnea and laboured breath in the later stages. The gross lesions of lung were haemorrhages, enlargement of interlobular septa, nodular formation and adhesion of the pleura.