• Molecules and Cells
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• 제28권3호
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• pp.209-213
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• 2009

Caenorhabditis elegans is a free living soil nematode and thus in its natural habitat, C. elegans encounters many different species of soil bacteria. Although some soil bacteria may be excellent sources of nutrition for the worm, others may be pathogenic. Thus, we undertook a study to understand how C. elegans can identify their preferred food using a simple behavioral assay. We found that there are various species of soil bacteria that C. elegans prefers in comparison to the standard laboratory E. coli strain OP50. In particular, two bacterial strains, Bacillus mycoides and Bacillus soli, were preferred strains. Interestingly, the sole feeding of these bacteria to wild type animals results in extended lifespan through the activation of the autophagic process. Further studies will be required to understand the precise mechanism controlling the behavior of identification and selection of food in C. elegans.

• Journal of Korean Neurosurgical Society
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• 제60권3호
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• pp.294-300
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• 2017

Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open craniotomy or endoscopy, stereotactic approaches with radiosurgery and gamma knife surgery or radiofrequency thermos-coagulation, and laser ablation have been introduced. Topographical dimension and the surgeon's preference are key factors for treatment modalities. Endoscopic disconnection has been one of the most favorable options performed in treating HHs. Here we discuss presurgical evaluation, patient selection, surgical procedures, and complications.

• International Journal of Advanced Culture Technology
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• 제8권4호
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• pp.287-293
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• 2020

More and more people are paying attention to the psychological pleasure and relaxation that sound hearing brings. In most cases, humans seem to have a special preference for natural sounds. Natural sounds are mainly white noise and pink noise such as wind, rain, waves, waterfall sounds, etc. All of these are often considered to be beneficial to human health, but in reality the same category of natural sounds is no different. It will be very different due to space, time and other factors. Each sound can be unique, so people's hearing experience is also different. This paper quantitatively analyzes the spectrum and brain waves to analyze the feeling of hearing the natural Broken Falls sound. In particular, we aim to objectively analyze the objective feeling of Broken Falls sound falling on the human auditory system through sound spectrum and brain waves.

• Journal of Korean Neurosurgical Society
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• 제65권5호
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• pp.622-632
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• 2022

Microvascular decompression is the gold standard for the treatment of trigeminal neuralgia (TN). However, percutaneous techniques still play a role in treating patients with TN and offer several important advantages and efficiency in obtaining immediate pain relief, which is also durable in a less invasive and safe manner. Patients' preference for a less invasive method can influence the procedure they will undergo. Neurovascular conflict is not always a prerequisite for patients with TN. In addition, recurrence and failure of the previous procedure can influence the decision to follow the treatment. Therefore, indications for percutaneous procedures for TN persist when patients experience idiopathic and episodic sharp shooting pain. In this review, we provide an overview of percutaneous procedures for TN and its outcome and complication.

• 대한인간공학회지
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• 제22권4호
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• pp.1-13
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• 2003

This study has investigated psychological responses to various TV advertisements by using EEG(electroencephalogram). In particular, it was assumed that the brain wave would show different patterns depending upon the style of the advertisement that could be categorized into two such as 'information transfer' type and 'emotional reaction' type. Ten healthy males participated in the experiment. EEG signal was extracted from six lobes such as right and left frontal, right and left occipital, right and left temporal while the subjects were watching TV advertisements. Alpha and beta relative power spectrum, and beta/alpha parameter were calculated to compare two kinds of advertisement each other. Additionally, subjective questionnaire was used to examine subject's response by using adjective words and preference test. In result, significant differences were found in left frontal and right occipital lobe in terms of beta/alpha between two different advertisements. And, subjects showed different preference between two advertisements. It was shown that the current method could analyze the brain reaction to advertisement quantitatively, that presented the possibility of using it to marketing research.

• 감성과학
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• 제22권4호
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• pp.65-74
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• 2019

Extant research has proposed that the Object-Spatial-Verbal cognitive style can elucidate individual differences in the preference for modality-specific information. However, no studies have yet ascertained whether this type of information processing evinces structural correlations in the brain. Therefore, the current study used voxel-based morphometry (VBM) analyses to investigate individual differences in gray matter volumes based on the Object-Spatial-Verbal cognitive style. For this purpose, ninety healthy young adults were recruited to participate in the study. They were administered the Korean version of the Object-Spatial-Verbal cognitive style questionnaire, and their anatomical brain images were scanned. The VBM results demonstrated that the participants' verbal scores were positively correlated with regional gray matter volumes (rGMVs) in the right superior temporal sulcus/superior temporal gyrus, the bilateral parahippocampal gyrus/fusiform gyrus, and the left inferior temporal gyrus. In addition, the rGMVs in these regions were negatively correlated with the relative spatial preference scores obtained by individual participants. The findings of the investigation provide anatomical evidence that the verbal cognitive style could be decidedly relevant to higher-level language processing, but not to basic language processing.

• 감성과학
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• 제14권2호
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• pp.311-320
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• 2011

인간의 감성에 직접적인 영향과 자극을 주는 색상자극에 대한 생체반응을 정량적으로 분석하기 위하여 3가지 색상 자극(Bright Yellow Red (BYR), Deep Green Yellow (DGY), Vivid Blue (VB))에 대한 뇌파 생리선호(Electroencephalography, EEG)와 선호도와의 상관관계를 연구하였다. 뇌파 분석을 통해 얻은 생체신호는 일반적인 색상의 이미지와 밀접한 상관관계가 있었다. 색온도가 낮을수록 뇌가 활성화 되었고(BYR ${\geq}$ DGY > VB), 좌뇌보다 우뇌가 더 큰 생체반응을 보였다. 전체적으로 주파수 별 뇌파값은 베타파${\geq}$세타파, 알파파> 감마파의 순이었다. 색온도가 낮을수록 Beta파의 뇌파 power 증가(BYR ${\geq}$ DGY > VB)하였고, 그러고 나머지 파(세타파, 베타파, 감마파)의 경우에는 색온도가 낮을수록 이들 주파수의 뇌파 power가 증가(BYR ${\geq}$ DGY > VB)하였다. 색상별 선호도와 뇌의 활성화의 상관관계는 색상에 대한 선호도가 높을수록 특정 주파수대의 뇌파가 활성화되었다. 선호도에 따른 뇌파반응은 좌 우뇌간에 유사한 생리적 반응을 보였으나, 후두부 보다는, 전두부에서 뚜렷한 상관관계를 보였다. 이러한 결과는 선호도가 높은 색상자극을 통해 특정 주파수 영역의 뇌파를 활성화가 가능하며, 색을 이용하는 다양한 분야(뷰티산업, 인테리어, 색채치료, 의상 등)에 적용가능성이 높다는 것을 의미한다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권5호
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• pp.487-493
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• 2017

The anterior cingulate cortex (ACC) is known for its role in perception of nociceptive signals and the associated emotional responses. Recent optogenetic studies, involving modulation of neuronal activity in the ACC, show that the ACC can modulate mechanical hyperalgesia. In the present study, we used optogenetic techniques to selectively modulate excitatory pyramidal neurons and inhibitory interneurons in the ACC in a model of chronic inflammatory pain to assess their motivational effect in the conditioned place preference (CPP) test. Selective inhibition of pyramidal neurons induced preference during the CPP test, while activation of parvalbumin (PV)-specific neurons did not. Moreover, chemogenetic inhibition of the excitatory pyramidal neurons alleviated mechanical hyperalgesia, consistent with our previous result. Our results provide evidence for the analgesic effect of inhibition of ACC excitatory pyramidal neurons and a prospective treatment for chronic pain.

• 한국전자통신학회논문지
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• 제16권1호
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• pp.89-94
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• 2021

본 논문에서는 학습 과제 수행 시 청각 자극이 뇌에 미치는 영향을 확인하기 위하여 뇌파 계측 실험을 통해 얻은 데이터로 분석한 결과를 제시하였다. 피험자가 수학적 과제를 해결하는 동안, 피험자의 선호도에 따라 구분한 선호 음악 및 비선호 음악을 청각 자극으로 제시하였으며, 수학적 과제는 암기형 및 절차형 과제로 구분하여 뇌파를 측정하였다. 이를 집중력과 관련된 뇌파의 주파수 대역인 세타파, SMR파 및 중간베타파로 나누어 상대 파워 스펙트럼 값을 비교하였다. 본 논문의 결과로는 무음악과 선호 음악 및 무음악과 비선호 음악을 비교한 경우에서 유의한 차이를 나타내는 채널을 관측할 수 있었으며, 공통적으로 전두엽 부위의 채널인 F3 및 F4에서 평균의 차이를 나타냈다. 유의미한 차이를 나타낸 채널들에서도 음악이 없는 경우보다 음악이 제시된 경우의 파워가 더 크게 나타났으며, 선호도에 따라서는 선호 음악이 비선호 음악의 경우보다 두뇌의 활성도가 크게 나타난다는 사실을 실험결과로부터 확인할 수 있었다.

• 한국실내디자인학회논문집
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• 제24권5호
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• pp.99-107
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• 2015

The purpose of this study is to analyze the change of visual stimulus of users to the space through the experiment of EEG and the satisfaction of users depends on the lighting. To do that, the results measured with EEG experiment focusing on Beta ${\beta}$ were compared to each other to figure out difference in the changes of the activation of human brain on lighting's situation as the lighting off and on in the same space. The difference in the results was verified according to the characteristic of users which classified with 4 types of the spatial sensitivities. The results of this study are as following. Firstly, the spacial sensitivity of user is to communicate well with the different senses with stimulus through interaction among the elements. At this time, the brain plays a major role in build the spacial sensitivity of users as the place to make form. Secondly, there are the differences in the activation of brain depends on lighting situation even in the same space. The stimulus into the brain became generally stronger in images with lighting on than off. Especially, the response in the occipital lobe which connected with the visual center turn out strongly in the image of 'modern natural'. Because the visual stimulus interact well with the bright color, the reflectional texture and the rough texture painted the dark color. Thirdly, the satisfaction of users changed with lighting in the space. But we could know that the satisfaction of users isn't be related to the visual stimulus through the results of this study. Finally, there isn't the difference in the activation degree of brain according to the characteristic which are preference of users into 4 types of the spatial sensitivity through the results came from ANCOVA(analysis of covariance) with SPSS Program 22.