• 생약학회지
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• 제24권1호
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• pp.78-86
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• 1993

Korean folk medicine 'Mul Bong Seon' has been used to cure hypertension and a toxicide. The botanical origin of the crude drug has been no pharmacognostical confirmation on it. To clarify the botanical origin of 'Mul Bong Seon', the morphologial and anatomical characteristics of the leaves of Impatiens species growing in Korea, i.e. I. balsamina, I. noli-tangere, I. textori, I. textori forma. pallescens were studied. As a result, it was clarified that 'Mul Bong Seon' was the leaf of Impatiens textori and Impatiens textori forma. pallescens.

• 생약학회지
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• 제26권2호
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• pp.168-174
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• 1995

Korean folk medicine 'Man Byung Cho' has been used to cure abdominal pain, athlete's foot and neuralgia. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'Man Byung Cho', the leaf morphology and anatomy were examined for the Korean species of Rhododendron subgenus Hymenanthes, such as R. brachycarpum G. Don, R. brachycarpum var. rosueum Koidz. and R. aureum Georgi. The study shows that 'Man Byung Cho' is the leaf of R. brachycarpum and R. brachycarpum var. roseum.

• 생약학회지
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• 제40권1호
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• pp.32-34
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• 2009

Korean folk medicine 'Ma Ga Mog' has been used as a remedy for rheumatis, cough and bronchitis in Korea. The botanical origin of the crude drug has been no pharmacognostical confirmation on it. To clarify the botanical origin of 'Ma Ga Mog', the anatomical characteristics of the bark of Sorbus amurensis Koehne, S. commixta Hedl. and S. sambucifolia (Cham. et Schltdl.) Roemer var. psuedo-gracilis C. K. Schneid. were studied. As a result, it was clarified that 'Ma Ga Mog' from Korea was the bark of Sorbus amurensis Koehne and S. commixta Hedl.

• 생약학회지
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• 제40권1호
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• pp.25-31
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• 2009

Korean folk medicine Bae Pung Dung has been used to cure a cold and jaundice. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of Bae Pung Dung, the morphological and anatomical characteristics of the leaves and stems of Solanum species growing in Korea, i.e. S. japonense Nakai, S. lyratum Thunb., S. nigrum L. were compared. As a result, it was determined that Bae Pung Dung was the whole plant body of Solanum lyratum and Solanum japonense.

• 생약학회지
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• 제40권2호
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• pp.99-102
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• 2009

'Whang Baig(黃柏)' is one of the crude drugs used mainly as a removing dampness, purging fire, detoxicating, and cleaning away heat of deficiency type. The botanical origin of the crude drug has never been studied pharmacognostically in Korea. To clarify the botanical origin of Whang Baig, the anatomical characteristics of Phellodendron amurense Rupr., Phellodendron insulare Nakai and Phellodendron molle Nakai were studied. As a result, it was clarified that Whang Baig from Korea was the bark of Phellodendron amurense and Phellodendron molle.

• 생약학회지
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• 제39권2호
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• pp.137-141
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• 2008

Korean folk medicine 'Ki Rin Cho' has been used to cure stanching and counteracting poison. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'Ki Rin Cho', the morphological and anatomical characteristics of Sedum species growing in Korea, i.e. S. aizoon, S. kamtschaticum and S. latiovalifolium were studied. As a result, 'Ki Rin Cho' was proved to be Sedum kamtschaticum and Sedum aizoon.

• 생약학회지
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• 제41권3호
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• pp.153-156
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• 2010

Korean folk medicine 'GulGeoRiIp' has been used to gastroentric trouble and indigestion from drinking. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of GulGeoRiIp, the morphological and anatomical characteristics of Daphniphyllum species growing in Korea, i.e. Daphniphyllum macropodum Miq. and D. glaucescens Blume were studied. As a result, GulGeoRiIp was proved to be the leaf of Daphniphyllum macropodum Miq.(Euphorbiaceae).

• 생약학회지
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• 제34권3호통권134호
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• pp.193-196
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• 2003

Korean folk medicine 'Bong Seon Wha Dae' has been used to cure constipation and acute gastritis by meat. The botanical origin of the crude drug has not been studied pharmacogostically. To clarify the botanical origin of 'Bong Seon Wha Dae', the morphological and anatomical characteristics of Impatiens species growing in Korea, I.e. I. Balsamina L., I. Noli-tan-gere L., I. Textori Miq. And I. textori Miq. for. pallenscens Hara were studied. As a result, 'Bong Seon Wha Dae' was proved to be the stem of I. Balsamina L.

• 대한한의학원전학회지
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• 제23권4호
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• pp.63-102
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• 2010

Purpose : To propose various types of clinical research which is feasible for botanical new drug (IND) development processes, and suggest essential steps to development of study protocol for IND. Methods : Literature-based discussions and one research group's experience is given regarding domestic act, regulation, and system. Results : In order to get an approval of IND for botanical drug in Korea there are several types of clinical research to conduct. In quality control steps for standardized medicinal herbs, case reports or case series can be conducted, and for good manufacturing practice(GMP) steps, we can conduct case reports, case series, and retrospective cohort studies. In addition, as long as we gathered good laboratory practice(GLP) data we can conduct up to quasi-experimental studies and clinical trials including investigator initiated trials. In order to conduct these studies development of study protocol is essential. First, we obtain historical evidence including target disease and indication, efficacy, safety, and endpoints by reviewing medical classics. Second, we obtain clinically and statistically important data by conducting non-clinical studies, observation studies, and quasi-experimental studies. Third, we generate research hypotheses and purposes and explore methodologies, endpoints, clinical practice guidelines, cost-effectiveness, and commercial potential. Finally, we develop study protocol with aid of biostatistician or expert in contract research organization. Discussions and conclusions : This study have obvious limitations in that most thoughts, suggestions, and proposes are from one research group's experience. Therefore, we hope to see various types of research in this topic and process from other research group as well.

• Natural Product Sciences
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• 제16권2호
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• pp.107-110
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• 2010

Curcuma caesia Roxb. (Zingiberaceae) is commonly known as 'Black turmeric'. In India it grows in West Bengal, Madhya Pradesh, Orissa, Bihar, North-East and Uttar Pradesh and is widely used by ethnic communities for various ailments. Rhizomes of the plant are used for sprains and bruises and are also employed in cosmetics. In West Bengal it is an important place in traditional system of medicine and is also used as a substitute for turmeric in fresh stage. Present communication deals with the detailed pharmacognostical evaluation of the rhizome sample. Inner part of the rhizome is bluish-black in colour and emits a characteristic sweet smell, due to the presence of essential oil. On steam distillation the rhizome yields an essential oil rich in camphor. A detailed HPTLC studies has been carried out for quantitative evaluation of active marker component. HPTLC, physico-chemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of C. caesia rhizome and may possibly help to differentiate the drug from its other allied species.