• Title/Summary/Keyword: border effect

Search Result 226, Processing Time 0.026 seconds

Effects of Ethanol on $Na^+-dependent$ Solute Uptake in Rabbit Renal Brush-Border Membrane Vesicles

  • Kim, Yong-Keun;Ko, Sun-Hee;Woo, Jae-Suk;Jung, Jin-Sup;Lee, Sang-Ho
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.3 no.2
    • /
    • pp.191-198
    • /
    • 1999
  • This study was undertaken to examine the effect of ethanol on $Na^+-dependent$ transport systems (glucose, phosphate, and dicarboxylate) in renal brush-border membrane vesicles (BBMV). Ethanol inhibited $Na^+-dependent$ uptakes of glucose, phosphate, and succinate in a dose-dependent manner, but not the uptakes of $Na^+-dependent.$ The $H^+/TEA$ antiport was reduced by 8% ethanol. Kinetic analysis showed that ethanol caused a decrease in $V_{max}$ of three transport systems, leaving $K_m$ values unchanged. Ethanol decreased phlorizin binding, which was closely correlated with the decrease in $V_{max}$ of $Na^+-glucose$ uptake. These results indicate that ethanol inhibits $Na^+-dependent$ uptakes of glucose, phosphate, and dicaboxylate and that the reduction in $V_{max}$ of $Na^+-glucose$ uptake is caused by a decrease in the number of active carrier proteins in the membrane.

  • PDF

Emission regulation and the carbon leakage: the impact of the consumption based carbon accounting and the border adjustment measure (배출규제가 탄소누출에 미치는 영향 분석 및 전망: 소비 관점의 탄소회계와 국경조치의 영향을 중심으로)

  • Oh, Inha
    • Environmental and Resource Economics Review
    • /
    • v.21 no.4
    • /
    • pp.851-891
    • /
    • 2012
  • The objective of this study can be presented as follows: First, given the consumption-based carbon accounting method which has now been claimed, this study reviews the emissions within Korea and the resulting position change in international society. Second, when each nation makes efforts to reduce carbon emissions under the Copenhagen Accord, this study, using the Computable General Equilibrium (CGE) model, reviews the resulting carbon leakage and analyzes the effect from the various border adjustment measures. However, reflecting uncertainties in the negotiation processes, this study attempts to apply scenarios with regards to the reduction-mandatory nation group. In addition, this study tries to observe the impact on Korea through testing the various border adjustment measures, including the free allocation and embodied carbon tariffs.

  • PDF

Changes in Phosphate Transporter Activity Evaluated by Phosphonoformic Acid Binding in Cadmium-Exposed Renal Brush-Border Membranes

  • Chung, Jin-Mo;Ahn, Do-Whan;Kim, Kyoung-Ryong;Park, Yang-Saeng
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.3 no.5
    • /
    • pp.513-519
    • /
    • 1999
  • Direct exposure of renal tubular brush-border membranes (BBM) to free cadmium (Cd) causes a reduction in phosphate (Pi) transport capacity. Biochemical mechanism of this reduction was investigated in the present study. Renal proximal tubular brush-border membrane vesicles (BBMV) were isolated from rabbit kidney outer cortex by Mg precipitation method. Vesicles were exposed to $50{\sim}200\;{\mu}M\;CdCl_2$ for 30 min, then the phosphate transporter activity was determined. The range of Cd concentration employed in this study was comparable to that of the unbound Cd documented in renal cortical tissues of Cd-exposed animals at the time of onset of renal dysfunction. The rate of sodium-dependent phosphate transport $(Na^+-Pi\;cotransport)$ by BBMV was determined by $^{32}P-Iabeled$ inorganic phosphate uptake, and the number of $Na^+-Pi$ cotransporters in the BBM was assessed by Pi-protectable $^{14}C-labeled$ phosphonoformic acid $([^{14}C]PFA)$ binding. The exposure of BBMV to Cd decreased the $Na^+-Pi$ cotransport activity in proportion to the Cd concentration in the preincubation medium, but it showed no apparent effect on the Pi-protectable PFA binding. These results indicate that an interaction of renal BBM with free Cd induces a reduction in $Na^+-Pi$ cotransport activity without altering the carrier density in the membrane. This, in turn, suggest that the suppression of phosphate transport capacity $(V_{max})$ observed in Cd-treated renal BBM is due to a reduction in $Na^+-Pi$ translocation by existing carriers, possibly by Cd-induced fall in membrane fluidity.

  • PDF

Effect of End-taping Treatments on Prevention of Drying Defects during Radio-Frequency/Vacuum Drying of Domestic Yellow Poplar Log Cross Section (엔드테이핑 처리들이 백합나무 원반의 고주파진공건조 중 건조결함 예방에 미치는 영향)

  • LEE, Nam-Ho;ZHAO, Xue-Feng;Chang, Sae-Hwan;SHIN, Ik-Hyun
    • Journal of the Korean Wood Science and Technology
    • /
    • v.36 no.6
    • /
    • pp.59-68
    • /
    • 2008
  • This study was carried out to investigate the effects of the Inside end-taping (Inside-ET) and Outside end-taping (Outside-ET) treatments on prevention of drying defects during radiofrequency/vacuum (RF/V) drying domestic yellow poplar log cross section with size of 20~75 mm in thickness and 120~470 mm in diameter. The treatments of Inside-ET and Outside-ET were quite effective for producing sound log cross sections with thinner than 33 mm and smaller than 270 mm in diameter. Even the 60 mm- and 75 mm-thick log cross sections, if the diameter was smaller than 30 cm, it might expect preventing formation of border checks by appropriate end-taping treatments. The positions of the observed border checks differed in diameter ranging at a relative radius about 0.50~0.63 diameter, and it was estimated that it was necessary to select the border position of end-taping treatment properly according to the diameter of log cross sections. It was observed that the radius of 0.3 diameter was the critical location for pretreatment for preventing formation of border checks in the log cross section with middle diameter. There were severe border checks and V-shaped cracks in the log cross section with large diameter. This was because of the severe variation of moisture content along radial direction of natural characteristic of domestic yellow poplar.

Effect of pH on PAH Transport in Brush Border Basolateral Membrane Vesicles of Rabbit Proximal Tubule (가토 신장 근위세뇨관의 Brush Border 및 Basolateral Membrane Vesicle에서 PAH 이동에 미치는 pH의 영향)

  • Kim, Yong-Keun;Woo, Jae-Suk;Lee, Sang-Ho
    • The Korean Journal of Physiology
    • /
    • v.22 no.2
    • /
    • pp.281-293
    • /
    • 1988
  • The effect of pH on the rate of PAH uptake was studied in rabbit renal basolateral membrane vesicles (BLMV) and brush border membrane vesicles (BBMV). In the absence of Na in incubation medium, a decrease in external $pH(pH_0)$ led to an increase in probenecid-sensitive PAH uptake by BLMV. In the presence of Na, the probenecid-sensitive PAH uptake was unaltered when the $pH_0$ decreased from 8.0 to 6.0 but further decrease in $pH_0$ to 5.5 increased significantly the uptake. The probenecid-sensitive PAH uptake was not affected by an alteration in pH per se in the absence of a pH gradient with or without the presence of Na. However, the presence of Na stimulated the probenecid-sensitive PAH uptake in all pH ranges tested over that measured in the absence of Na. A similar pattern of pH dependence on the PAH uptake was observed in BBMV but the presence of Na did not alter the probenecid-sensitive PAH uptake in the presence and absence of a pH gradient. Kinetic analysis for BLMV showed that Na or pH gradient increased Vmax of the probenecid-sensitive PAH uptake without a change in Km value. These results suggest that PAH is transported by $OH^-/PAH$ exchange process in the luminal membrane, but the pH dependence in the BLMV is not unequivocally consistent with an anion exchange process. The PAH transport is dependent on Na in BLMV but not in BBMV.

  • PDF

Factors Influencing Fintech's Customer Loyalty for Cross Border Payments: Mediating Customer Satisfaction (국경간 핀테크 결제거래에서 고객충성도에 영향을 미치는 요인에관한 연구: 고객만족의 매개효과를 중심으로)

  • Rehman, Usman;Ha, Kyu Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.16 no.6
    • /
    • pp.287-297
    • /
    • 2021
  • The goal of this study is to investigate and provide information to the Fintech Industry on the main factors responsible for customer loyalty via the mediating effect of customer satisfaction. Secondly, providing traditional banking reasons for customer shifts from banking to Fintech, therefore these factors could be more focused. The consumer choices presented in this study can thus serve as a foundation for further research into post-adoption behaviors associated with Fintech for cross-border payments. This study examines consumer evaluations of how key attributes of fintech using mobile payment services affect their choice by using a conjoint analysis approach, which allows for the approximation of user preferences for specific features. In our study we have used SPSS 26 to test the reliability and mediation effect on the sample size of 348 people who regularly used Fintech for cross border payments. All the questionnaires were prepared if the customers were given fintech as an option instead of traditional banks to send their remittances abroad. The result shows that(Service Quality, Customer's trust and product quality) effecting customer satisfaction significantly would be very helpful for the current fintechs working for home remittances to improve these factors and would serve as a benchmark for the upcoming fintech startups and traditional banks to focus on these factors and catch up the fintech Industry. Finally, it is argued that, in order to be successful, focusing on service quality, customer trust, and product quality triggered customer loyalty for the Fintech in comparison to other traditional options for cross-border payments via the mediation effect of customer satisfaction.

The Congruence between the Sponsor-Sponsored Unit and its Effect on Behavioral Responses

  • Toukabri, Maher;Najjar, Faouzi;Yaich, Besma Amamou
    • International Journal of Computer Science & Network Security
    • /
    • v.22 no.3
    • /
    • pp.113-128
    • /
    • 2022
  • This research emphasizes on the role of congruence between the sponsor and the sponsored unit that effect sponsor's brand image, attitudes towards it and the memorization of the sponsor's name. The contribution of this research is highlighted especially during the sponsorship of national football team during the 2018 football World Cup. Because of the increasing cost of sponsorship, it has become essential for sponsors to understand how the direct and indirect audience responds to their congruence with the sponsored sports team; and which of the two types of audiences is more and more receptive to their actions. Specifically researchers were not conscious about the level of congruence that optimizes the effects on the sponsor. Therefore, this research aims to characterize the congruence between the marks of the sponsors and the football team through a survey administered face to face. Then, we test the global model to determine if the sponsorship operation has more impact on the sponsor in case of high, low or average congruence? To respond to our research questions we selected two samples from customers that were exposed to the sponsoring actions two ascertain the exploratory and confirmatory steps. The first sample consists of 200 interviewees and the second 400 are considered as an acceptable representation guarantee for our research. In addition, we propose to validate the research model and test the inherent hypotheses that analysis the relationship between the chosen constructs.

Contralateral Intraparenchymal Hemorrhage Following Aneurysmal Clipping

  • Kim, Jae-Hoon;Yi, Hyeong-Joong
    • Journal of Korean Neurosurgical Society
    • /
    • v.43 no.3
    • /
    • pp.162-164
    • /
    • 2008
  • Post-clipping intraparenchymal hemorrhage of the contralateral hemisphere is a very unusual phenomenon in a patient with aneurysmal subarachnoid hemorrhage, unless there is an underlying condition. We report a complicated case of 47-year-old man, who underwent uneventful clipping of ruptured aneurysm and experienced vasospasm two weeks later. Vasospasm was treated by intra-arterial nimodipine and systemic hyperdynamic therapy. One week thereafter, he became unconscious due to intraparenchymal hemorrhage on the anterior border-zone of contalateral hemisphere, but intraoperative and pathologic findings failed to disclose any vascular anomaly. We suggest that the anti-spastic regimens cause local hemodynamic redistribution through the vasodilatory effect and in turn, resulted in such an unexpected bleeding.

A study on the Exchange of Tourists Encouraged by the Inter-Korean Railway Connection (Focusing on the Operation of Sightseeing Train) (남북철도 연결에 따른 관광 교류에 대한 연구(관광열차 운행을 중심으로))

  • 박홍순;신택현
    • Proceedings of the KSR Conference
    • /
    • 2002.05a
    • /
    • pp.41-46
    • /
    • 2002
  • This paper deals with the exchange of tourists and the operation of sightseeing train encouraged by the inter- Korean cross-border railway project. First of all, how the inter-Korean cross-border railway project has developed will be discussed. After this, tile present tourism state, facilities, the state of railways and roads of North Korea, and major tourist attraction around the Kyonguisun will be shown. And then, several aspects on the agreements between the Korean National Railroad (KORAIL) and North Korean railroad system will be summarized. And, finally, the economic effect of the line including the operation schedule of the Kyonguisun sightseeing train, the demand forecast, the computation of railway fare, and profit sharing will be depicted.

  • PDF

Acupuncture Application Case Report for Symptom Relief of Oral Leukoplakia (구강 백반증의 증상 완화에 대한 침치료 적용 사례)

  • Park, Sung-gu;Jo, Eun-hee;Choi, Hangyul;Hong, Jieun;Park, Min-cheol
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.34 no.2
    • /
    • pp.97-101
    • /
    • 2020
  • Oral leukoplakia is the most common premalignant lesion of the oral mucosa. This case report presents the effect of acupuncture on Oral leukoplakia. The 67 years old male patient who has suffered for 2 years was treated with Right side Saam acupucture Damjeonggyeok(BL66, GB43, LI1, GB44) without other treatment. Acupuncture was performed for 15 minutes. The effect of acupuncture was evaluated as photographic change and visual analog scale(VAS) of subjective symptoms in oral cavity. After 87th acupunture treatment during 226 days, Leukoplakias were decreased at the right side of ventral tongue and the left border of the tongue and the lower lip. Furthermore, ulcer, erosion at the left border of the tongue were disappeared and VAS of Burning pain in the tongue decreased from 8 to 2. Although acupuncture is unusual treatment for Oral Leukoplakia, this case report suggested the effectiveness of using Damjeonggyeok on Oral Leukoplakia according to Saam acupuncture method.