• Korean Journal of Human Ecology
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• v.5 no.1
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• pp.75-80
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• 1996

The immunogenecity of low molecular weight ($MW{\le}30,000$) immunogens in laying hens was investigated. Immunogens were insulin derivatives and ${\beta}$-lactoglobulin(${\beta}-Lg$). Insulin derivatives were reduced- carboxymethylated(RCM) insulin, and RCM-A and RCM-B chain of insulin. The yolk antibodies against RCM-A chain of insulin appeared after the first immunization. The yolk antibodies against RCM-B chain of insulin were elicited 5 weeks after the third booster injection. Although the anti-RCM-B chain yolk antibodies recognized native insulin, the anti-RCM-A chain yolk antibodies didn't native insulin. The anti-RCM insulin yolk antibodies were induced after the second booster injection and showed cross-reactivities with native insulin. On the other hand, ${\beta}-Lg$ showed stronger immunogenecity than insulin derivatives. The $anti-{\beta}-Lg$ yolk antibodies were produced after the second booster injection and the peak titer was reached 3 weeks after the third booster injection.

• Journal of Dental Rehabilitation and Applied Science
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• v.26 no.1
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• pp.69-75
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• 2010

Botulinum toxin type A(BTX-A) has been applied successfully to treat masseteric hypertrophy. However it can cause muscle weakness. This study was designed to measure the change in maximum bite force(MBF) after BTX-A injection into human masseter muscle and to evaluate the influence of a booster(repeated) injection. Thirty volunteers completed 18-week follow-up and MBF was measured. At 18 weeks after the first injection, a booster injection was given to 14 patients and they were followed up until 18 weeks from the booster injection. The mean MBF was approximately 20% lower at 2 weeks than before the injection, and it recovered gradually after 4 weeks to return to the preinjection level at 12 weeks. The MBF differed significantly between before the injection and at 2, 4, and 8 weeks after the injection(p<0.05). In booster injection group(n=14),the MBF decreased markedly at 6 weeks(p<0.05),and it recovered gradually in 12 weeks. The MBF was significantly reduced after booster injection of BTX-A into the human masseter muscle. The degree of discomfort experienced by the subjects had little effect on normal mastication.

• Journal of Preventive Medicine and Public Health
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• v.20 no.2 s.22
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• pp.280-286
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• 1987

For evaluating the boosting (anamnestic) effects of the most recent commercially produced plasma derived heat-inactivated hepatitis B vaccine (A. Co.), 117 adults with naturally acquired antibody to hepatitis B surface antigen (anti-HBs) were selected at random. In addition, out of case immunized at zero and 1 month, and boosted at 6 months (primary boosting) by conventional vaccine (B. Co), inactivated by pepsin digestion and formalin treatment, 11 cases who showed elevated titer after primary boosting were also submitted to the study. The results were as follows: 1) Out of the 117 subjects with naturally acquired anti-HBs, 6(5.1%) showed isolated anti-HBs and the titers were below 10 ratio units (RU). Negative seroconversion was seen in 4(3.4%) of the 117 cases at 12 months after the screening and, of these cases, 3 showed isolated anti-HBs and the titers were below 10 RU. 2) Eighty-three percent of the cases with naturally acquired isolated anti-HBs below 10 RU did not respond to a booster injection with 3 us dose of A. Co. vaccine at all, but 90% of the other subjects responded. 3) The anti-HBs titers of all the 11 cases who showed a rise of more than 10 RU (increased GMT, 28.04) at one month after primary booster injection by $20{\mu}g$ dose of B. Co. vaccine decreased at 19 months after the primary booster. And 3 subjects (27.3%) of the 11 reached negative seroconversion. All of the 11 cases, who had secondary booster injection with $3{\mu}g$ dose of A. Co. vaccine at 19 months after primary boosting, showed increased anti-HBs titer at least 20 RU or more (increased GMT, 57. 72) at one month after the boosting. According to the above results in the anti-HBs screening survey for the purpose of immunization with hepatitis B vaccine, subjects with isolated anti-HBs below 10 RU should be regarded as being in an unimmunized state. In cases who are in risk circumstances, immunized primarily with a $20{\mu}g$ dose of B. Co. vaccine, a secondary booster injection should be given within 2 years after initiation of primary immunization and a $3{\mu}g$ booster dose of A. Co. vaccine can be reliably used.

• Journal of Power System Engineering
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• v.17 no.6
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• pp.5-10
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• 2013

Diesel engines have the advantages of good fuel efficiency and low emissions. Therefore, car makers have been developed various kinds of diesel engine management system to clean up emissions while improving fuel efficiency. One of them is the common rail system. In the common rail system, diesel fuel is injected into the combustion chamber at ultra high pressures up to 1,800 bar to ensure more complete combustion for cleaner exhaust gas, and highly precise multiple injection reduces NOx emission, combustion noise and vibration. Generally speaking, common rail system consists of booster pump, high pressure pump, common rail, injectors, control valves, and sensors. The high pressure pump receives low pressure fuel from the booster pump and supply high pressure fuel to injectors through the high pressure common injection rail. Therefore, high pressure pump has an important role in common rail system. In this paper, we have investigated the performance of high pressure pump of common rail system.

• Geomechanics and Engineering
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• v.24 no.2
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• pp.129-141
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• 2021

The vacuum preloading method has been used in many countries for soil improvement and land reclamation. However, the treatment time is long and the improvement effect is poor for the straight-line vacuum preloading method. To alleviate such problems, a novel combined air booster and straight-line vacuum preloading method for shallow ground treatment is proposed in this study. Two types of traditional vacuum preloading and combined air booster and straight-line vacuum preloading tests were conducted and monitored in the field. In both tests, the depth of prefabricated vertical drains (PVDs) is 4.5m, the distance between PVDs is 0.8m, and the vacuum preloading time is 60 days. The prominent difference between the two methods is when the preloading time is 45 days, the injection pressure of 250 kPa is adopted for combined air booster and straight-line vacuum preloading test to inject air into the ground. Based on the monitoring data, this paper systematically studied the mechanical parameters, hydraulic conductivity, pore water pressure, settlement and subsoil bearing capacity, as determined by the vane shear strength, to demonstrate that the air-pressurizing system can improve the consolidation. The consolidation time decreased by 15 days, the pore water pressure decreased to 60.49%, and the settlement and vane shear strengths increased by 45.31% and 6.29%, respectively, at the surface. These results demonstrate the validity of the combined air booster and straight-line vacuum preloading method. Compared with the traditional vacuum preloading, the combined air booster and straight-line vacuum preloading method has better reinforcement effect. In addition, an estimation method for evaluating the average degree of consolidation and an empirical formula for evaluating the subsoil bearing capacity are proposed to assist in engineering decision making.

• Korean Journal of Veterinary Research
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• v.35 no.1
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• pp.87-94
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• 1995

Western immunoblot analysis of antigen of T sergenti merozoite revealed that the immunodominant proteins of this organism were characterized as the 18KD, 29KD, 34KD, 45KD and 105KD in Korea. The 34KD and 45KD among those immunodominant proteins of the parasite were isolated and their amino acid sequences from the $NH_2$-terminus were determined and synthesized. They respective polypeptides were cationized to enhance their antigenicity, fortified with Freund's adjuvant and tested for immunogenicity in rabbits and cattle. The results obtained were as follows; 1. Theileria sergenti merozoite antigen was shown in 120KD, 100KD, 66KD, 45KD, 34KD and 30KD in western immunoblot using serum of rabbits immunized with 34KD synthetic polypeptide and 70KD, 58KD, 55KD and 45KD using bovine serum. In western immunoblot, 45KD, 34KD and 30KD were recognized by immunized rabbits, and 50KD and 45KD by cattle sera immunized with 45KD synthetic polypeptide, respectively. 2. The ELISA utilizing the synthetic polypeptides demonstrated significant antibody response to the respective peptides. After the 2nd booster injection, an OD of 0.760(preimmunization 0.132) in rabbits and an OD of 0.645(preimmunization 0.488) to 34KD synthetic polypeptide in cattle were observed. In animals immunized with 45KD synthetic polypeptide, after the 2nd booster injection, an OD of 0.640(preimmunization 0.144) in rabbit, and an OD of 0.776 (preimmunization 0.477) in cattle were measured. 3. After the 2nd booster the reciprocal IFA titer was 1:64 in rabbits and 1:512 in cattle immunized with the 34KD synthetic polypeptide. The IFA titre was observed as 1:512 in rabbit and 1:1,024 in cattle in immunized with the 45KD synthetic polypeptide.

• Pediatric Infection and Vaccine
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• v.8 no.2
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• pp.150-159
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• 2001

Purpose : We need to reconsider booster vaccination schedule of Japanese encephalitis vaccination. To do that we evaluate the long-term immunogenicity and the incidence of adverse events with inactivated mouse brain derived Nakayama Japanese encephalitis vaccine. Methods : We tested neutalizing antibody for 311 elementary school students by plaque reduction neutralizing test(PRNT) at USAMC-AFRIMS(United States Armed Forces Research Institute of Medical Science/Department of Virology). We evaluated vaccine related adverse events by spontaneous reporting prospectively among 15,487 vaccinees who were vaccinated at public health center and 2,277 elementary school students who were immunized previously by a questionnaire and school health record. Results : According to the time interval from the last booster injection of 311 children, PRNT antibody titers gradually decreased as the interval increased; 239 mIU/mL, 188 mIU/mL, 134 mIU/mL, 49 mIU/mL each at 6, 18, 30, 42 months after the last booster injection. The seropositivity rates were 98%, 99%, 95.6%, 71.4% each at 6, 18, 30, 42 months after the last booster injection. There were 21(0.13%) cases with systemic reactions among 15,487 vaccinees who had visited the hospital by prospective passive reporting system at public health center. According to the questionnaires and school health records in elementary school students, local induration and pain were 17.4% and 14.8%, respectively. Systemic reactions including fever, vomiting, rash were reported in few cases. Conclusion : Biannual booster vaccination that has been recommended so far should not be necessary. Surveillance for adverse events with inactivated mouse brain derived Nakayama vaccine should be strengthened to better assess the number of cases and reactions associated with immunization.

• Journal of the Korean Society of Safety
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• v.22 no.4
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• pp.32-36
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• 2007

When the vacuum system for the process of $SiH_{4}$ gas used in the semiconductor and FPD field is partially vented from vacuum to atmospheric state, a fire often occurs due to auto-ignition of $SiH_{4}$ gas. In order to prevent the fire, the concentration of $SiH_{4}$ should be kept under LFL. This means that the higher capacity pump is needed to meet the process conditions as well as the condition that the concentration of $SiH_{4}$ should be kept under LFL. In this article, we conducted the injection of the dilution gas at the manifold between booster pump and dry pump compared with the typical method that the dilution gas was injected into inlet port of booster pump using computer simulation. According to the result, we can flow further more purge gas for safety without any change of the condition in the process chamber, which means that the higher capacity pump is not required for safety in some cases.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.18 no.5
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• pp.464-470
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• 1985

Some eels Anguilla japonica, ranging from 16 to 23 g in their weight(average: 20 g), were sampled at the private eel farming company equipped with water recycling system, located at Kimhae city, Kyungnam Province, Korea. Three kinds of vaccine were prepared with Vibrio anguillarum (EPM-8406) isolated at National Fisheries University in Korea for the immune response experiment against eels; those vaccines were made by inactivating the strain with $0.3\%$ formalin for 24 hrs at $25^{\circ}C$, heating for 3 mins or for 15 mins at $121^{\circ}C$, respectively. The various optimal vaccination conditions for the control of vibriosis in the fish were investigated based on the cultivation temperature, vaccination concentration and booster effect. The maximum titer rapidly increased with higher temperature up to $23^{\circ}C$, but there were little differences between $23^{\circ}C\;and\;28^{\circ}C$. The formalin-killed vaccine showed good efficacy at the injection concentration of above $10^8$ cells per fish and little effect at the below $10^7$ cells. The booster effect on the vaccination showed good efficacy above twice-injections with little difference between the numbers of injection.

• Plant Journal
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• v.9 no.2
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• pp.42-45
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• 2013

The worldwide issue of greenhouse gas reduction has recently drawn great attention to carbon capture and storage(CCS). In this study, we developed a 10,000 ton/year pilot injection plant for geological storage of carbon dioxide. Major components of the pilot plant include a pressure pump, a booster pump, and an inline heater to bring liquid carbon dioxide into its supercritical state. The test results show that the pilot plant readily achieves the injection pressure and temperature, showing satisfactory control performance. The overall power consumption is 2,000 ~ 2,500 W, more than 75% of which consumed by the pressure pump. This study will facilitate varied research on greenhouse gas reduction as the only domestically developed system for geological injection.