• 대한수의학회지
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• 제40권4호
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• pp.755-762
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• 2000

The aim of this investigation was to examine the effects of osteocalcin, bone-specific alkaline phophatase, estrogen, insulin-like growth factor-I (IGF-I), Ca, P and bone mineral density on osteoporosis induced by ovariectomy in rats. Female Sprague-Dawley 30 rats of three-forth's birth, weighing $215{\pm}10g$, were divided into two groups including the sham operation group(5 heads) and ovariectomy group(25 heads). They were fed normal diets for 2 weeks before the experimental operation and for 8 more weeks after operation. The level of osteocalcin, TALP, BALP, estrogen, bone mineral density and IGF-I were increased in experimental group, but a little increased in sham operation group at same period. The change of rates of osteocalcin, TALP, BALP, estrogen, bone mineral density and IGF-I were significantly higher in experimental group than sham operation group. $Ca^{2+}$ was not changed between two groups and P was significantly decreased in experimental group and Ca/P ratio was higher in experimental group than sham operation group. Body weights were increased in all two groups and growth rate per day was higher in experimental group than sham operation group. However, femur weight I body weight ratio was lower in experimental group than sham operation group.

• 동의생리병리학회지
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• 제20권5호
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• pp.1226-1232
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• 2006

This study was carried out to investigate the effects of Cervi Pontotrichum cornu and Carthami semen on the serum osteocalcin level, bone mineral density, bone trabecular area and cortical thickness index in ovariectomized rats. Femal Sprague-Dawley rats were divided into 5 groups. Non-ovariectomized groups were divided into commertial diet fed(normal group) and calcium free basal diet fed(sham operation group). Ovariectomized groups were divided into 3groups, calcium free basal diet fed group(control group or ovariectomized group), 10% Cervi Pontotrichum cornu supplemented diet fed group and 10% Carthami semen supplemented diet fed group. After 4 weeks diet fed, serum osteocalcin level, bone mineral density, bone trabecular areas and cortical thickness index were analyzed. The bone mineral density and bone trabeculae area were significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The osteocalcin level was significantly decreased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The trabecular area(%) in epiphysis of tibia was significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The cortical thickness index in distal diaphysis of tibia was significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. the alkaline phosphatase level was significantly decreased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. These results suggest that Cervi Pontotrichum cornu and Carthami semen might have inhibitory effects on osteoporosis by increasing bone mineral density and accerelating bone formation in ovariectomized rats.

• 환경위생공학
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• 제19권3호
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• pp.71-80
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• 2004

The purpose of this study was to find the relationship between osteoporosis and various factors such as general personal background, physical activity, menstruation, daily life and dietary habit. The following are the results of this study: 1. In the relationship of osteoporosis status with general personal background, the risk of osteoporosis increased with age. Active women with higher education, high income and jobs tended to have less risk of osteoporosis. Women with earlier menarche had a tendency of having thicker bone mineral density. 2. As for disease related to bone mineral density, stomach disease, thyroid, bone damage, and bad teeth conditions were significant factors affecting bone mineral density. Women with those diseases and family history of osteoporosis were more likely to have osteoporosis. 3. In relation to food intake regular diet of dairy products, anchovy, or meat showed significantly less risk of osteoporosis. 4. In relation between dietary habits and bone mineral density, unbalanced diet had statistically less probability of osteoporosis. It is important for genetically disposed women to prevent osteoporosis in advance by considering acquired factors like life-style and medication.

• Nutrition Research and Practice
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• 제7권4호
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• pp.309-314
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• 2013

This study was conducted to investigate the relationship among the current status of calcium intake from milk and milk products, physical growth and bone mineral density in 664 male and female middle school and high school students aged 15-17 years. In the study, the current status of calcium intake from milk and milk products was analyzed, and the height, body composition, and bone mineral density of the right heel bone (calcaneus) were measured. The daily calcium intake of milk and milk products was calculated as the 'dairy equivalent of calcium', which is the calcium content in 200 mL of white milk. The cutoffs of tertiles of the dairy equivalent of calcium were calculated and then the subjects were categorized into 3 groups according to the tertiles, Q1 group (lower intake group), Q2 group (middle intake group) and Q3 group (upper intake group). The daily calcium intake of milk and milk products in Q1, Q2 and Q3 groups was 16.2 mg, 99.7 mg, and 284.0 mg, respectively, and the ratio of milk and milk product consumption to the daily total calcium intake was 5.4%, 27.4%, and 49.7%, respectively. The ratio of total calcium intake to the daily recommended intake in study subjects was 30.5% in Q1, 42.3% in Q2, and 60.7% in Q3, with significant differences (P < 0.05). Height, body weight, BMI, and % of body fat in three tertile groups (Q1, Q2 and Q3) were not significantly different. However, the T scores for bone mineral density in female students in three tertile groups (Q1, Q2 and Q3) was significantly different (P < 0.05). The study showed that the intake of milk and milk products in adolescents, particularly in girls, can improve the bone mineral density without increasing body weight, and thus confirmed that milk intake is important in adolescence.

• Journal of Nutrition and Health
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• 제36권4호
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• pp.359-367
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• 2003

The purpose of this study was to examine the impact of soy protein and soy isoflavones on bone and mineral density in young female Sprague-Dawley rats. Fifty eight rats (body Weight 75 $\pm$ 5 g) were randomly assigned to one of four groups, consuming casein, soy protein concentrate, soy protein isolate (57 mg isoflavones/100 g diet) or casein added isoflavones (57 mg isoflavones /100 g diet). All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXImus (GE Lunar Co, Wisconsin, USA) in spine and femur on 3, 6, 9 weeks after feeding. The serum and urine concentrations of Ca and P were determined. Diet did not affect weight gain and mean food intake. Food efficiency ratio was lower In soy protein groups. The serum concentration of Ca and P were not changed by soy protein and isoflavones. Urinary Ca and P excretion were not significantly different. Spine BMD was significantly increased by soy protein isolate on 3 and 6 weeks after feeding. Femur BMD was significantly increased in the groups of soy protein isolate and isoflavones adding on after 9 weeks. Therefore, soy protein with rich isoflavones may be beneficial on spine and femur BMD increasement in growing female rats.

• Nutrition Research and Practice
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• 제1권4호
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• pp.328-334
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• 2007

The purpose of this study was to examine the relationship between nutrient intake and bone mineral density (BMD) of elderly women in Daegu, Korea. In this study, the bone mineral densities of 101 elderly women in Daegu were measured, and their nutrient intake, dietary habits, and maternal factors were determined through a survey. The subjects were divided into the normal group, the osteopenia group, and osteoporosis group to find out if there is a correlation between bone mineral density and maternal factors, dietary habits, and nutrient intake through their T-scores, analyzed according to the standards of WHO. Classification by T-scores of the participants were the normal group 25.7%, the osteopenia group 39.6%, the osteoporosis group 34.7%. Menopause age of the osteoporosis group was lower, postmenopausal period was longer, and last delivery age was significantly higher than the normal group (p<0.05). Osteoporosis group had a lower percentage of 'everyday' fruit and vegetable intakes and higher percentage of 'never' dairy intake than of the normal group. Vitamin A, vitamin $B_1$, and vitamin $B_2$ intakes of participants in the osteoporosis group were lower than those in the normal group (p<0.05). In conclusion, nutritional education is necessary to encourage high intake of milk and vegetables and fruits along with calcium, vitamin A, $B_1$, and $B_1$ intakes and low intake of sodium for the prevention of elderly women's osteoporosis.

• 여성건강간호학회지
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• 제14권1호
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• pp.12-19
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• 2008

Purpose: This study was to identify the influencing factors in postmenopausal women's bone mineral density (BMD). Method: The sample for the study was 107 postmenopausal women who took the BMD test. For BMD measurement, lumbar spine BMD(L2-5) was measured by Dual-energy X-ray absorptiometry(DEXA). Data was collected by questionnaires on the selected variables such as reproductive factors and life style factors. Result: In reproductive factors, parity shows significant differences with BMD (F=4.16, p=.02). In life style factors, diet (F=3.01, p=.05) and exercise (F=7.39, p=.00) show significant differences with BMD. Excercise, diet and parity accounted for 42.0% of the influencing factors in Postmenopausal Women's Bone Mineral Density. Conclusion: The influencing factors in postmenopausal women's bone mineral density were excercise, diet and parity. In this paper, it is suggested that the influence of reproductive and life style factors in postmenopausal women's BMD should be studied by long term and needs repeated research. This study can be used as foundation material for nursing education program development for osteoporosis prevention and improvement.

• 대한디지털의료영상학회논문지
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• 제10권2호
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• pp.5-10
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• 2008

Thanks to recent development of science and technology, economic standard has been improved and life expectation has been gradually increased. Accordingly, disease aspect and demand for health have been changed in the concept from conventional center of disease to health improvement As the health issue in middle and senior age has also been vital in the national health, osteoporosis, one of the physical maladies occuring in these age group, is on the rise as a matter of important concern so that the researches on the osteoporosis have being accomplished actively in several medical domains. Research has been earned out for 735 examined objects, who have received medical examination of bone mineral density in the volunteer medical service of Daegu and Kyungbuk province for recent 4 years. The result indicated that serious osteoporosis prevailed over osteoporosis for male while osteopenia was majority to osteoporosis and that abnormal bone mineral density was more prominent than normal bone mineral density for both male and female. This study is to present basic data which is indispensible to preparation of senior citizen dominated society afterward, investigating the prevalence rate of osteoporosis.

• 대한물리의학회지
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• 제5권2호
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• pp.289-300
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• 2010

Purpose : This study was to explore the effects of knee joint taping exercise on muscle strength, bone mineral density, pain and IGF-1 in blood of elderly women with knee Osteoarthritis. Methods : Thirty elderly women with knee osteoarthritis were divided into three groups: the taping with exercise group (n=10), the regular exercise group (n=10) and control group (n=10). Participants' muscle strength, bone mineral density, pain and IGF-1 in blood were measured three times : before exercise, after 6 weeks, and after 12 weeks. Results : Participants in both exercise (taping & non-taping) groups showed improvement in muscle strength, bone mineral density, pain and IGF-1 in blood after 6 and 12 weeks compared to before exercise. In particular, the taping exercise group had a greater effect on muscle strength than the regular exercise group. Conclusion : Both exercise programs considerably improved muscle strength, bone mineral density, reduced pain and IGF-1 in blood in elderly women with knee Osteoarthritis. The knee joint taping exercise is perhaps a better exercise to improve muscle strength than the regular exercise in treating elderly women with knee Osteoarthritis

• Journal of Sport and Applied Science
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• 제7권2호
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• pp.21-28
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• 2023

Purpose: This study was to investigate the effect of a 12-week plyometric training on body composition, physical fitness and bone mineral density in obese male adolescents. Method: Twenty adolescent boys who are obese were randomly assigned to a control group (CON, n=10) or plyometic exercise group (EXE, n=10). The EXE group was performed 3 times per week for 12 weeks. The body composition, physical fitness, and bone mineral density were measured before and after the 12 weeks intervention. Results: The results of this study were as follows: i) In EXE group, the fat mass was significantly decreased between pre and post, whereas the difference of the body weight, BMI, and LBM were not significant. ii) Among the physical fitness factors, grip strength, muscular endurance, and 2 0m shuttle running were significantly improved but flexibility did not show any significant difference. iii) The bone mineral density was significantly improved between pre and post in EXE group. Conclusion: These results suggested that plyometric training for 12 weeks may be effective in improving body composition, physical fitness, and bone mineral density in obese adolescents. Further implications were discussed.