• 제목/요약/키워드: bone exposure

검색결과 384건 처리시간 0.02초

분화성 갑상선암과 공존한 부갑상선 선종 (Coexistent Parathyroid Adenoma and Well Differentiated Thyroid Careinoma)

  • 이준호;정웅윤;박정수
    • 대한두경부종양학회지
    • /
    • 제13권2호
    • /
    • pp.241-246
    • /
    • 1997
  • It has become evident in recent years that parathyroid adenoma and well differentiated thyroid cancer occur together more than would be expected by chance alone. However, the association between them is not well understood. We have experienced 4 cases of coexistent parathyroid adenoma and well-differentiated thyroid cancer during the past 16 years. None of them had a familial incidence or a history of radiation exposure. Three cases showed symptomatic hypercalcemia(including renal stones, bone pain, joint pain) and in two of them(patient 1 and patient 2), thyroid abnormalities were detected preoperatively by neck ultrasonography or neck CT for evaluation of parathyroid lesions. However, in patient 3, a parathyoid humor was identified and removed incidentally during the course of thyroidectomy. In 3 cases, surgeries for thyroid carcinoma and parathyroid adenoma were performed during the same exploration of the neck, but in patient 4, thyroidectomy preceded parathyroidectomy; The interval between thyroidectomy and subsequent parathyroidectomy was 11 yeras. The thyroid tumors in 3 cases were papillary carcinoma, the sizes of which ranged from 1.0 cm to 1.5 cm in greatest diameter. The remaining case(patient 4) was minimal invasive follicular carcinoma. Total or near-total thyroidectomy with various types of cervical lymphnode dissection and bilateral neck exploration for the parathyroid lesion was performed in 3 cases with papillary carcinoma. Ipsilateral lobectomy and contralateral partial thyroidectomy with consequent unilateral neck exploration for the parathyroid tumor was performed in the case of follicular cancer. In our experience, parathyroid adenoma and well-differentiated thyroid carcinomas can be coexistent and we felt that the attention to the hypercalcemic patients would be needed for detection of this rare condition.

  • PDF

맞춤형 지르코니아 지대주와 완전도재관을 이용한 상악 전치부 임플란트 보철 수복 (Reconstruction of upper anterior by implant using customized zirconia abutment and all ceramics: a clinical report)

  • 김자영;서재민
    • 구강회복응용과학지
    • /
    • 제30권1호
    • /
    • pp.81-92
    • /
    • 2014
  • 상악 전치부에 임플란트를 이용해 심미적으로 수복 하는 것은 많은 어려움이 따른다. 이는 치조골 흡수와 치간 유두 수축 등과 같은 임플란트 주변 경, 연조직 문제와 금속지대주 및 금속도재관의 변연노출과 낮은 광투과도 등의 보철적 한계 때문이다. 이에 본 증례에서는 경, 연조직의 증대술 및 성형술, 발치 후 즉시 식립 등과 함께 임시수복물의 장기간 사용 및 수정으로 임플란트 주위 연조직의 형태와 건강을 형성한 후, 맞춤형 인상 코핑을 사용하여 이를 최종 모형에 재현하였다. 또한 맞춤형 지르코니아 지대주와 완전 도재관을 이용해 최종 수복함으로써 기능적이고 심미적인 결과를 얻었기에 이를 보고하고자 한다.

전립선 암에서 Bicalutamide 사용으로 생긴 간질성 폐질환 1예 (Bicalutamide-induced Interstitial Lung Disease)

  • 김양균;김이형;이재진;최천웅;유지홍;박명재;강홍모
    • Tuberculosis and Respiratory Diseases
    • /
    • 제68권4호
    • /
    • pp.226-230
    • /
    • 2010
  • Androgen deprivation therapy, which is the standard treatment for metastatic prostate cancer, includes nonsteroidal antiandrogenic drugs, such as flutamide, nilutamide and bicalutamide. Of them, bicalutamide rarely induces interstitial pneumonia. We report a case of bicalutamide-induced interstitial pneumonia. A 68-year old male diagnosed with prostate cancer and multiple bone metastases presented with dry cough and low grade fever for 3 days. He had taken bicalutamide (50 mg/day) for 13 months. High resolution computed tomography revealed ground glass opacity in his right upper lung. The laboratory studies showed no eosinophilia in the serum and bronchoalveolar lavage fluid. Despite the use of antimicrobial agents for 2 weeks, the extent of the lung lesions increased to the left upper and right lower lung. He had no environmental exposure, collagen vascular disease and microbiological causes. Under the suspicion of bicalutamide-induced interstitial pneumonia, bicalutamide was stopped and prednisolone (1 mg/kg/ day) was initiated. The symptoms and radiologic abnormalities were resolved with residual minimal fibrosis.

곰취 추출물의 항돌연변이성 및 유전독성억제효과 (Antimutagenic and Antigenotoxic Effects of Ligularia fischeri Extracts)

  • 함승시;이상영;오덕환;정성원;김상헌;정차권;강일준
    • 한국식품영양과학회지
    • /
    • 제27권4호
    • /
    • pp.745-750
    • /
    • 1998
  • The antimutagenic and antigenotoxic effects of ethanol, methanol, water and non-heating ethanol extract of Ligularia fischeri were investigated using Ames test and micronucleus test. Four solvent extracts by themseleves did not induce mutagenesis. The four extract of 200㎍/plate showed approximately 84.7%, 77.1%, 72.5% and 71% inhibitory effect on the mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) and 67.9%, 66.8%, 64.6% and 56% inhibition on the mutagenesis by 4-nitroquinoline-1-oxide(4NQO) against TA100 strain, whereas 70.2%, 60.9%, 61.9% and 52.8% inhibitions were observed on the mutagenesis induced by 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indol(Trp-P-1) in the presence of 200㎍/plate. TA100 strain was more sensitive than TA98 strain by four kinds of extracts on antimutagenesis. The effects of Ligularia fischeri extracts on the frequencies of micronucleated poly chromatic erythrocytes(MNPECs) induced by MNNG were investigated in the bone marrow. Ten, 20, 40 and 80mg g/kg of each extract were administered to animals immediately after injection of MNNG and the exposure time was 36 hours. Inhibitory effects of Ligularia fischeri ethanol extracts were 12%, 35.3%, 58.8%, and 57%, in the presence of 20, 40, 60 and 80mg/kg, respectively whereas methanol extracts showed 15.5%, 32.7%, 50.8%, and 57.9% inhibitory effects, respectively. Both extracts showed enhanced antimutagenic and antigenotoxic effects. These results showed a good correlation between antimutagenic effects in in vitro and in in vitro assay.

  • PDF

상악동 내 노출된 임플란트의 치유양상 (The Healing of Exposed Implant Surfaces in A Maxillary Sinus Cavity)

  • 이승호;최병호;주석강;정재형;유태민;이현중;이경욱;허진영
    • Journal of Periodontal and Implant Science
    • /
    • 제35권4호
    • /
    • pp.1073-1079
    • /
    • 2005
  • 1. Objective. The aim of this study was to investigate whether dental implant exposure to the maxillary sinus cavity increases the risk of maxillary sinus complications. 2. Study design. An implant was placed bilaterally in the maxillary sinus of eight adult female mongrel dogs in a way that it penetrated the bone and mucous membrane of the maxillary sinus floor to the extent of 2 mm, 4 mm, or 8 mm. The implants were left in place for six months. 3. Results. Radiographic and histologic examinations did not show any signs of pathologic findings in the maxillary sinus of the eight dogs. 4. Conclusion. This study indicates that implant protrusion into the maxillary sinus cavity is not related to the development of sinus complications.

Complication incidence of two implant systems up to six years: a comparison between internal and external connection implants

  • Chae, Sung-Wook;Kim, Young-Sung;Lee, Yong-Moo;Kim, Won-Kyung;Lee, Young-Kyoo;Kim, Su-Hwan
    • Journal of Periodontal and Implant Science
    • /
    • 제45권1호
    • /
    • pp.23-29
    • /
    • 2015
  • Purpose: This study was conducted to compare the cumulative survival rates (CSRs) and the incidence of postloading complications (PLCs) between a bone-level internal connection system (ICS-BL) and an external connection system (ECS). Methods: The medical records of patients treated with either a ICS-BL or ECS between 2007 and 2010 at Asan Medical Center were reviewed. PLCs were divided into two categories: biological and technical. Biological complications included >4 mm of probing pocket depth, thread exposure in radiographs, and soft tissue complications, whereas technical complications included chipping of the veneering material, fracture of the implant, fracture of the crown, loosening or fracture of the abutment or screw, loss of retention, and loss of access hole filling material. CSRs were determined by a life-table analysis and compared using the log-rank chi-square test. The incidence of PLC was compared with the Pearson chi-squared test. Results: A total of 2,651 implants in 1,074 patients (1,167 ICS-BLs in 551 patients and 1,484 ECSs in 523 patients) were analyzed. The average observation periods were 3.4 years for the ICS-BLs and 3.1 years for the ECSs. The six-year CSR of all implants was 96.1% (94.9% for the ICS-BLs and 97.1% for the ECSs, P=0.619). Soft tissue complications were more frequent with the ECSs (P=0.005) and loosening or fracture of the abutment or screw occurred more frequently with the ICS-BLs (P<0.001). Conclusions: Within the limitations of this study, the ICS-BL was more prone to technical complications while the ECS was more vulnerable to biological complications.

구강악안면영역에서의 MedporTM의 임상적용 (THE USE OF MEDPORTM(POROUS HIGH-DENSITY POLYETHYLENE) IN ORAL AND MAXILLOFACIAL REGION)

  • 박광범;여환호;김수관
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • 제21권1호
    • /
    • pp.60-64
    • /
    • 1999
  • Recently, for the reconstruction of bony defect and cosmetic improvement, many graft materials and implants have been widely used in the various surgical situations. The alloplastic materials have many advantages such as simplicity of operation, no additional need of surgery, and easy manipulation. The $Medpor^{TM}$(porous high-density polyethylene, Porex Co., USA) was initially studied in 1972 for surgical implant and introduced as an implant material for oral and maxillofacial region by Sauer and King in 1988. This material permits full ingrowth of bone into the implants, substantially increasing the implant's incorporation into the recipient site. It can be shaved during the surgery, which results in an improvement and prefabricated various size and shapes to fit into the surgical defect. The $Medpor^{TM}$ was used in 32 patients from 1995 to 1997 at the maxillofacial region. It was used for paranasal augmentation in 24 cases, for malar augmentation in 2 cases, for infraorbital augmentation in 2 cases, for mandibular angle augmentation in 2 cases, for mandibular body augmentation in 2 cases, for chin vertical augmentation in 1 case. It was mainly fixed with miniplate or screw. There were few complications except one infection and one exposure of the implant.

  • PDF

동종조직에서의 방사선 멸균효과에 대한 연구 (THE EFFECT OF STERILIZATION OF GAMMA IRRADIATION ON ALLOGENEIC TISSUE MATERIALS)

  • 이은영;김성진;박우윤;김경원;엄인웅;류주연
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • 제27권6호
    • /
    • pp.523-527
    • /
    • 2005
  • Allograft donations are commonly found to be contaminated. The most of tissue banks has promoted the use of ionizing radiation for the sterilization of biological tissues. The potential for transmission of human infectious diseases and contamination of microorganism has created serious concern for the continued clinical use of hard and soft-tissue allografts. Tissue banks have employed 15-25kGy for sterilization of hard and tendon allografts, which, according to the national standards, approaches the level at which the tissue quality is adversely affected for transplantation. The donations of allogeneic tissues to the Korea Tissue Bank over a 2-year period were reviewed, and the incidence and bacteriology of contamination were detailed. Clinical outcomes were determined for donors who had positive cultures at the time of retrieval and during the processing and they were compared with those of post sterilization. After exposure of the frozen block bone to 25kGy and the processed tissues to 15kGy of gamma irradiation, the authors were able to demonstrate complete inactivation of the bacteria. The aim of this study was to obtain the effects of gamma irradiation and the irradiation dose according to the type of tissue, through conventional microbiologic test without on influence of biocompatibility in allografts. The contamination rate after the final irradiation sterilization is 0% in the processed allografts. This may be due to the fact that the gamma radiation and processing steps are effective to control contamination.

만곡된 치근을 가진 상악 중절치의 교정적 견인을 이용한 치험례 (ORTHODONTIC TRACTION OF IMPACED CENTRAL INCISOR WITH DILACERATED ROOT)

  • 김영진;박호원;이주현
    • 대한소아치과학회지
    • /
    • 제32권3호
    • /
    • pp.437-443
    • /
    • 2005
  • 상악 중절치는 만곡이 주로 일어나는 치아로 만곡에 의해 치아가 매복된 경우 인접치아가 기울어지거나 정중선이 편위되는 등의 교정적 문제를 일으킬 수 있다. 이러한 치아의 만곡은 외상과 낭종, 기타 원인으로 발생하며 치아의 형태나 치근의 만곡도, 악골 내의 위치, 자발적인 맹출 가능성 등을 고려하여 치료를 결정해야 한다. 치아가 순설측으로 만곡된 경우는 자발적인 맹출이 어려우므로 발치를 포함한 보철적 처치나 발치 후 재식술, 외과적 치관노출을 동반한 교정적 처치 등을 고려해 볼 수 있다. 본 증례는 치근이 순측으로 만곡되어 매복하고 있는 상악 중절치를 폐쇄맹출법을 이용해 교정적으로 견인하여 양호한 치료결과를 얻었기에 보고하고자 한다.

  • PDF

미성숙 영구치에서 혈소판 농축 섬유소를 적용한 생활 치수 치료 : 증례보고 (VITAL PULP THERAPY USING PLATELET-RICH FIBRIN IN AN IMMATURE PERMANENT TOOTH : CASE REPORTS)

  • 이가영;이상호;이난영
    • 대한소아치과학회지
    • /
    • 제40권2호
    • /
    • pp.120-126
    • /
    • 2013
  • 심한 우식을 보이는 미성숙 영구치 치료에 있어서 치수생활력을 보존하는 것은 중요하다. 치수절단술을 시행 시 생체적합성이 있는 재료를 이용하여 치료함으로써 남아있는 생활력이 있는 치수를 보호하며 미성숙 영구치의 치근 성장을 도모할 수 있다. 혈소판 농축 섬유소는 환자의 혈액을 직접 채취하여 적용하기 때문에 생체적합성이 뛰어나며 다양한 성장인자를 함유하고 있어 치수생활력을 유지하고 미성숙 영구치의 치근 발육을 촉진시킬 수 있다. 본 증례에서는 심한 치아 우식증을 보이는 미성숙 영구치에서 치수절단술 시행 후 남아 있는 치수 상부에 혈소판 농축 섬유소를 적용하였다. 정기적인 검진 결과 미성숙 영구치의 치근 성장 및 정상적인 치아 주위 조직들이 관찰되었다. 향후 장기간의 임상적 관찰이 필요할 것이며 더 많은 임상 증례를 바탕으로 한 연구가 필요할 것이다.