• Environmental Analysis Health and Toxicology
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• v.18 no.1
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• pp.57-61
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• 2003

Plasma melatonin in the seasonal light-period is circadian rhythmically secreted. Maximal secretion showed at 14 o'clock in summer- and winter-like period, but minimal secretion showed at 5 o'clock in summer-like period and at 8 in winter-like period. These times of minimal secretions were at the beginning of light period. Plasma melatonin in the light period is secreted 62.5％ more than in the dark period in summer- like period and 45.9％ more in winter- like period. Total plasma melatonin in winter-like period is secreted 56.5％ more than in summer-like period. The weights of testis (-20.8％) and body (-7.1％) were reduced in the winter-like period. By the increase of plasma melatonin in mice, body - and testis -weights are decreased, on the contrary by the decrease of plasma melatonin in mice, body and testis weights are increased. In view of the results so far achieved melatonin changes on the body weight and reproductive organ in mice. It is presumed that melatonin effects on the metabolism and sex hormone.

• Journal of Nutrition and Health
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• v.32 no.7
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• pp.827-837
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• 1999

Presently Sasang constitutional medicine draws public attention and a diet based on this theory in gaining popularity. However, scientific data are not available to probe the effects of constitutional diet and the correlations between constitution and food consumptions. Thiry-four healthy subjects[26 females and 8 males] with Tae-eum(females: 5, males: 7), So-yang(females: 9)and So-eum(females: 12, males: 1), were studied. Subjects were not told the kind of constitutional diets they were consuming. Tae-eum constitutional diet was given to all subjects more than 2 meals a day for 8 weeks. The Sasang constitutional classification, food frequency questionnaire and food habits were assessed. The anthropometric assessment, dietary assessment, health status assessment and blood analysis were carried out before and after taking the Tae-eum constitution diet. In case of females, the body weights and BMI were different among the constitutional groups in the following order : Tae-eum constitutional diet. In case of females, the body weights the body weights and BMI were different among the constitutional groups in the following order: Tae-eum>So-yang>So-eum. In case of males, the body weights and BMI of Tae-eum were significantly higher than those of So-eum. In general, habitual food consumption of all of these four groups were very close to those for each of Sasang constitutional types described by Sasang medicine. After 8-weeks of Tae-eum diet, the health status and blood biochemical parameters were not significantly changed.

• Korean Journal of Veterinary Service
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• v.33 no.4
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• pp.417-421
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• 2010

The aim of this study was to determine the changes of body weight, organ weight, hematological values and biochemical parameters by testosterone (Testos) on the orchidectomized (Orch) rats. The animals were divided into 4 groups. Intact group (n=10) received no treatment and operation. Sham group (n=10) received only sham operation and no treatment. Orch group received operation and no treatment. Orch+Testos received operation and testosterone. The body weights of each group increased, but that of Orch+Testos group was significantly lower in Orch+Testos group than in all the other groups. There were significant differences (P<0.05, P<0.001) of body weights between Orch+Testos group and all the other groups. Also, organ weights such as heart, liver, spleen and kidney were measured. The heart weights were significantly lower (P<0.001) in the Orch+Testos group than in all the other groups. The liver weights in the Orch+Testos group were significantly differences in comparison with those in the Sham (P<0.001) and Orch group (P<0.05). On the other hand, there were no significantly differences in the organ weights of spleen and kidney between the Orch+Testos group and the any other groups. The hematological values of white blood cell (WBC), red blood cell (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were no significant differences in any other groups. The concentrations of serum total protein and albumin increased significantly (P<0.05) in the Orch+Testos group as compared to that in the Orch group. However, there were no significant differences in Ca, IP and Mg in any other groups. We conclude that testosterone was significantly decreased the body weight in the orchidectomized rats. Our findings suggest that testosterone may influence the process of lipid packaging and absorption in the orchidectomized rats.

• Korean Journal of Veterinary Service
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• v.34 no.1
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• pp.69-73
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• 2011

This was conducted to determine the effects of body weight, organ weight, hematological values and biochemical parameters by L-carnitine (Carn) on the orchidectomized (Orch) rats. The animals were divided into 4 groups. Intact group (n=10) received no treatment and operation. Sham group (n=10) received only sham operation and no treatment. Orch group received operation and no treatment. Orch+Carn received operation and L-carnitine. The body weights of each group increased, but that of the Orch+Carn group were significantly lower than those in all the other groups. There were significant differences (P<0.05, P<0.001) of body weights between Orch+Carn group and all the other groups. Also, organ weights such as heart, liver, spleen and kidney were measured. The heart weights were significantly lower (P<0.001) in the Orch+Carn group than those in Intact and Sham groups, respectively. The weights of liver and kidney in the Orch+Carn group were significantly differences (P<0.001) in comparison with those in all the other groups. Also, the spleen weights were significantly lower (P<0.05) in the Orch+Carn group than those in Intact and Sham groups, respectively. The hematological values of mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) were significantly differences (P<0.05, P<0.01, P<0.001) in comparison with those in all the other groups. On the other hand, the hematological values of white blood cell (WBC), red blood cell (RBC) and mean corpuscular hemoglobin concentration (MCHC) were not significantly different in any other groups. The concentrations of total cholesterol (T-chol), triglyceride (TG) and high density lipoprotein (HDL) decreased significantly (P<0.05) in the Orch+Carn group as compared to those in the Orch group. We conclude that L-carnitine was significantly decreased the body weight in the orchidectomized rats. Our findings suggest that L-carnitine may influence the process of lipid packaging and absorption in the orchidectomized rats.

• Korean Journal of Animal Reproduction
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• v.5 no.1
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• pp.73-79
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• 1981

This study was conducted to find out the effects of estrogen and progesterone on body weight, uterine weight and serum prolactin levels on the growing female rats which were ovariectomized. For this purpose, 125 heads of rats (Wistar-Imamichi strain), 28 days old, were devided into 5 groups; OVariectomy(Ovx.), ovariectomy treated with estrogen(Ovx.+Est.), ovariectomy treated with progesterone(Ovx.+Prog.), ovariectomy treated with estrogen and progesterone(Ovx.+Est.+Prog.) and control group. Twenty-five heads of rats were arranged to each group, and changes of body weights were weekly checked. On the other hand, every 5 heads of rats in each group were sacrificed at 1, 2, 3, 4 and 5 weeks after treatments with time elapse for measuring concentrations of serum prolactin and for investigating the weights of ulterus. Prolactin concentrations in the serum were analyzed by radioimmunoassay. The results obtained are as follows; 1. The body weights were increased slightly in Ovx. in comparison with Ovx.+Prog., Ovx.+Est.+Prog., Ovx.+Est. and control groups, but there were not significant among the compared groups at all observation times. 2. The uterine weights in all treatment groups were decreased significantly (P<0.01) compared with control groups at all observation times. But the weights in Ovx. and Ovx.+Prog. groups were lower than those in Ovx.+Est. and Ovx.+Est.+Prog.. 3. Serum prolactin concentrations were increased slightly in control group in comparison with other groups at 1 and 2 weeks increased slightly in control group in comparison with other groups at 1 and 2 weeks after treatment. But compared with control group, the concentrations Ovx.+Est. and Ovx.+Est.+Prog. were high level, and those in other groups were low level in the order of Ovx. and Ovx.+Prog. groups at 3, 4 and 5 weeks after treatment. There were not significant among the compared groups at all observation times. 4. The results obtained in this study suggest that when ovariectomized rats receive 1$\mu$g estrogen and 3mg progesterone daily, that had no effect on body weight and serum prolactin concentrations while significantly effect on the weight of uterus.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.7
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• pp.914-918
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• 2004

The random regression model methodology was applied into the estimation of genetic parameters for body weights in Chinese Simmental cattle to replace the traditional multiple trait models. The variance components were estimated using Gibbs sampling procedure on Bayesion theory. The data were extracted for Chinese Simmental cattle born during 1980 to 2000 from 6 national breeding farms, where records from 3 months to 36 months were only used in this study. A 3 orders Legendre polynomial was defined as the submodel to describe the general law of that body weight changing with months of age in population. The heritabilities of body weights from 3 months to 36 months varied between 0.31 and 0.48, where the heritabilities from 3 months to 12 months slightly decreased with months of age but ones from 13 months to 36 months increased with months of age. Specially, the heritabilities at eighteenth and twenty-fourth month of age were 0.33 and 0.36, respectively, which were slightly greater than 0.30 and 0.31 from multiple trait models. In addition, the genetic and phenotypic correlations between body weights at different month ages were also obtained using regression model.

• Nutrition Research and Practice
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• v.3 no.2
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• pp.89-94
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• 2009

The aim of this study was to investigate if dietary Chlorella vulgaris(chlorella) intake would be effective on cadmium(Cd) detoxification in rats fed dietary Cd. Fourteen-week old male Sprague-Dawley(SD) rats weighing $415.0{\pm}1.6\;g$ were randomly divided into two groups and fed slightly modified American Institute of Nutrition-93 Growing(AIN-93G) diet without(n=10) or with(n=40) dietary Cd(200 ppm) for 8 weeks. To confirm alteration by dietary Cd intake, twenty rats fed AIN-93G diet without(n=10) and with(n=10) dietary Cd were sacrificed and compared. Other thirty rats were randomly blocked into three groups and fed slightly modified AIN-93G diets replacing 0 (n=10), 5 (n=10) or 10% (n=10) chlorella of total kg diet for 4 weeks. Daily food intake, body weight change, body weight gain/calorie intake, organ weight (liver, spleen, and kidney), perirenal fat pad and epididymal fat pad weights were measured. To examine Cd detoxification, urinary Cd excretion and metallothonein (MT) concentrations in kidney and intestine were measured. Food intake, calorie intake, body weight change, body weight gain/calorie intake, organ weight and fat pad weights were decreased by dietary Cd intake. Urinary Cd excretion and MT concentrations in kidney and small intestine were increased by dietary Cd. After given Cd containing diet, food intake, calorie intake, body weight change, body weight gain/calorie intake, organ weights and fat pad weights were not influenced by dietary chlorella intake. Renal MT synthesis tended to be higher in a dose-dependent manner, but not significantly. And chlorella intake did not significantly facilitate renal and intestinal MT synthesis and urinary Cd excretion. These findings suggest that, after stopping cadmium supply, chlorella supplementation, regardless of its percentage, might not improve cadmium detoxification from the body in growing rats.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.6
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• pp.764-771
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• 2012

Direct and maternal genetic heritabilities and their correlations with body weight at 5 stages in the life span of purebred Berkshire pigs, from birth to harvest, were estimated to scrutinize body weight development with the records for 5,088 purebred Berkshire pigs in a Korean farm, using the REML based on an animal model. Body weights were measured at birth (Birth), at weaning (Weaning: mean 22.9 d), at the beginning of a performance test (On: mean 72.7 d), at the end of a performance test (Off: mean 152.4 d), and at harvest (Finish: mean 174.3 d). Ordinary polynomials and Legendre with order 1, 2, and 3 were adopted to adjust body weight with age in the multivariate animal models. Legendre with order 3 fitted best concerning prediction error deviation (PED) and yielded the lowest AIC for multivariate analysis of longitudinal body weights. Direct genetic correlations between body weight at Birth and body weight at Weaning, On, Off, and Finish were 0.48, 0.36, 0.10, and 0.10, respectively. The estimated maternal genetic correlations of body weight at Finish with body weight at Birth, Weaning, On, and Off were 0.39, 0.49, 0.65, and 0.90, respectively. Direct genetic heritabilities progressively increased from birth to harvest and were 0.09, 0.11, 0.20, 0.31, and 0.43 for body weight at Birth, Weaning, On, Off, and Finish, respectively. Maternal genetic heritabilities generally decreased and were 0.26, 0.34, 0.15, 0.10, and 0.10 for body weight at Birth, Weaning, On, Off, and Finish, respectively. As pigs age, maternal genetic effects on growth are reduced and pigs begin to rely more on the expression of their own genes. Although maternal genetic effects on body weight may not be large, they are sustained through life.

• Toxicological Research
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• v.22 no.4
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• pp.339-348
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• 2006

Misaengtang (MST), a formula of Korean herbal medicines, has been used as a weight-controlling recipe. We have investigated two experiment of body weight regulation by MST In rats. i) The anti-obesity effect of MTS on a high fat diet-induced obesity, male Sprague-Dawley rats were fed with a high-fat diet containing 30% in the absence or presence of MST (0.3, 1 or 3%) or a reference orlistat (0.05%) for 6 weeks. ii) weight-decrease effect of MST on normal diet, same animal were fed with a normal diet in the absence or presence of MST (3%) for 6 weeks. And the body weights, daily feed and water consumptions, organ weights, fat weights serum biochemistry were measured. In both experiments, MST and orlistat did not affect the body weight gain. But orlistat significantly increased the feed and water consumptions, leading to low-feed efficiency, and orlistat markedly reduced abdominal, paratesticular and perirenal fat weights, although increased the kidney weights. In MST, low dose (0.3%) of MST decreased the perirenal fat and increased the kidney weights in rats fed HFD, and MST 3% decreased the abdominal fat weights in rats fed normal diet. In addition, Orlistat caused changes in parameters of hepatotoxicity (AST and glucose), nephrotoxicity (BUN and B/C ratio) and lipid metabolism (HDL and triglycerides). In comparison, MST decreased AST, ALP and ALT, the hepatotoxicity markers, and somewhat improved the hepatic fatty degeneration. Taken together, it is suggested that MST does not exert anti-obesity activity as well as remarkably direct effects, but MST may be potentially benefit for dietary cure and exercise-cure of obesity.

• Nutrition Research and Practice
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• v.14 no.2
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• pp.160-166
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• 2020

BACKGROUND/OBJECTIVES: The obese population is rapidly increasing because of reduced physical activity and a Westernized diet; consequently, various chronic diseases are more prevalent. With the increasing interest in body shape and appearance, research on body shape perceptions and accompanying weight control behaviors are needed for healthy weight management. SUBJECTS/METHODS: A cross-sectional survey was conducted on randomly selected 536 (209 men and 327 women) aged 20 to 65 years. Body mass index (BMI), body-shape perception, weight control behavior, quality of sleep, and place of residence were collected using self-reported questionnaires. Multivariable logistic regression analysis was conducted using complex design in each groups. Collected data were analyzed using the SAS 9.4 statistical package, and the significance level was set at P < 0.05. RESULTS: When these two variables were divided into four groups, they were found to influence dieting attempts. People with abnormal weights who were dissatisfied with their body shapes attempted dieting 5.23 times more than those with healthy weights and satisfaction with their body shapes. Further, those with normal weights but dissatisfaction with their bodies attempted dieting 4.45 times more than those who were satisfied with their shapes. Subjects in their 20s attempted dieting 2.53 times more than those in their 30s and 40s, and female subjects attempted dieting 2.24 times more than male subjects. CONCLUSIONS: A correct perception of one's shape can be an important factor for dietary behavior, as body shape perceptions and dieting attempts are strongly related. Additionally, healthy weight management and nutrition education are important elements to incorporate into a weight control program aimed at preventing excessive weight control behaviors and promoting correct perceptions of body shape.