• Journal of muscle and joint health
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• v.16 no.2
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• pp.116-124
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• 2009

Purpose: The purpose of this study was to examine the effects of a Tai Chi exercise program on physical function and physiological variables in patients with degenerative arthritis. Methods: The study utilized a nonequivalent control group with pretest-posttest design. Data collection was done with the elders from two welfare institutions in C-city between July I and September 22, 2007. The participants were assigned either to an experimental group (n=24) or to a control group (n=22). The experimental group participated in Tai Chi exercise for 60 minutes per session, twice a week for 12 weeks and the control group received the education about arthritis for 3 weeks. Results: Except for $VO_2max$, weight, and body fat rate, the elders in the experimental group showed significant improvement in physical function (grip strength, flexibility, balance), and physiological variables (BP) compared to the control group. Conclusion: The results suggest that Tai Chi exercise would partially improve physical function, and physiological variables. Further studies are needed to determine the effects on physical fitness and physiological variables after Tai Chi exercise in this population.

• The Korean Journal of Food & Health Convergence
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• v.8 no.1
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• pp.21-30
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• 2022

This study proposed a multiple regression equation for predicting VO2max of elderly men and women using functional performance variables required to conduct daily activities. The subjects of this study were 58 elderly men (72.4±5.9 yrs) and 117 elderly women (73.4±4.5 yrs) aged 65-90 who belong to the senior welfare center. The maximal graded exercise test using a cycle ergometer and functional performance representing muscle strength, endurance, static and dynamic flexibility, mobility, and agility were measured. For statistical processing, multiple regression analysis was performed, and the statistical significance level was α = .05. As a result, the VO2max estimation formula for the elderly was 0.419 (standing up and sitting down a chair) + 0.199 (leg endurance against wall) + 5.383, and R2=0.406. In addition, the VO2max estimation formula for elderly women is - 0.737 (standing up from a supine position) - 0.144 (waking around two cones in a figure 8) - 0.135 (%body fat) + 0.042 (one leg balance with eyes open) + 29.395, R2=0.367 was calculated. The conclusion is that if the maximal graded exercise test is not available, it is considered that VO2max of the elderly can be predicted properly by using the estimation formula calculated based on the functional performance variable.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.523-535
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• 2023

Objectives: This study aims to investigate the anti-inflammatory effect and improvement of dyslipidemia on Hyangsapyeongwi-san. Methods: In this study, HUVEC cells were cultured and treated with Hyangsapyeongwi-san to measure intracellular KLF2, eNOS, MCP-1, ICAM-1, and VCAM-1 gene expression levels related to anti-inflammation. The weight of experimental animals administered with Hyangsapyeongwi-san was measured, blood samples were biochemically analyzed, and liver tissues were reviewed to research histological changes. Results: Gene expression levels in the cells treated with Hyangsapyeongwi-san generally showed a meaningful anti-inflammatory effect. The body weight of the experimental animals decreased, and total cholesterol, triglyceride, and LDL-cholesterol in the blood generally declined while HDL-cholesterol tended to increase. Fat accumulation between hepatocytes was also reduced after the administration of Hyangsapyeongwi-san. Conclusions: This study confirmed that Hyangsapyeongwi-san has the effect of suppressing vascular inflammatory responses through the regulation of genes involved in the vascular inflammatory process and improving dyslipidemia through the reduction of blood lipids and weight loss.

• Journal of Preventive Medicine and Public Health
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• v.56 no.4
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• pp.338-347
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• 2023

Objectives: Young children's feeding characteristics can play an important role in eating habits and health during later childhood. This study was conducted to examine the associations of feeding characteristics with dietary patterns and obesity in children. Methods: This study utilized data from the Korea National Health and Nutrition Examination Survey conducted between 2013 and 2017. In total, 802 toddlers were included, with information on their demographic characteristics, feeding practices and duration, and 24-hour recall obtained from their parents. Feeding characteristics were categorized into feeding type, duration of total breastfeeding, duration of total formula feeding, duration of exclusive breastfeeding, and age when starting formula feeding. Dietary patterns were identified based on factor loadings for the food groups for 3 major factors, with "vegetables & traditional," "fish & carbohydrates," and "sweet & fat" patterns. Overweight/obesity was defined as ≥85th percentile in body mass index based on the 2017 Korean National Growth charts for children and adolescents. Multiple regression analysis was conducted to examine associations between feeding characteristics and dietary patterns. The association between dietary patterns and obesity was analyzed using multivariable logistic regression analysis. Results: The early introduction of formula feeding was inversely associated with the "vegetables & traditional" pattern (β=-0.18; 95% confidence interval [CI], -0.34 to -0.02). A higher "vegetables & traditional" intake was associated with a lower risk of obesity (odds ratio, 0.48; 95% CI, 0.24 to 0.95). Conclusions: Feeding characteristics are associated with dietary patterns in later childhood, and dietary patterns were shown to have a potential protective association against obesity.

• Journal of the Korean Society of Food Culture
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• v.22 no.5
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• pp.645-651
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• 2007

Male weanling Sprague Dawley rats were used to evaluate the effect of dietary rice starch with different particle size on growth performance, intestinal function and proliferation. There were two dietary treatment: rice starch (RS), ultra finely pulverized rice starch with less than $15{\mu}m$ size (PRS). They were eight rats per treatment. In vitro digestibility, body weight change and organs weight were evaluated. Serum GPT, GOT and blood urea nitrogen were analyzed. Transit time, short chain fatty acid contents of cecum, and cell proliferation of duodenum and jejunum were measured. In vitro digestibility of PRS was higher than that of RS. Rats fed ultra finely pulverized rice starch for 3 weeks grew faster than rats fed rice starch. PRS group has higher weights of liver, kidney, spleen and epididymal fat pad, perhaps as a result of increased digestibility. GPT and GOT were not different between two groups. Blood urea nitrogen was higher in RS-fed rats than that of PRS-fed rats. Feeding ultra finely pulverized rice starch resulted in a proliferation of duodenum significantly. These results suggest that ultra finely pulverized rice starch increases the growth performance in weanling animals with reduced number of cells in the cell cycle of small intestine.

• Natural Product Sciences
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• v.29 no.2
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• pp.91-97
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• 2023

Mangosteen peel extract is a xanthone group, that plays an important role in anti-angiogenesis. This study investigated mangosteen peel extract on cerebral neovascularization in type 2 diabetes mellitus (DM) rats. This study used 36 rats, randomized into six groups: C1 (negative control); C2 (high fat diet (HFD) and mangosteen peel extract at 200 mg/kg BW); C3 (HFD and diabetic); E1, E2, and E3 (HFD, diabetic, and extract at 100, 200, and 400 mg/kg BW respectively). All groups were measured body mass index (BMI), homeostasis model assessment-insulin resistance (HOMA-IR) and β cell function (HOMA-B), and histopathological feature of cerebral vascular (CV). There were significant differences in BMI, HOMA-IR, HOMA-B, and the mean number of CV (all p < 0.05) among treatment groups. E1-3 groups had a significantly lower level of blood glucose and HOMA-IR, and a higher level of HOMA-B and BMI (all p < 0.05) which tends to reduce cerebral neovascularization. HOMA-IR independently had a positive effect to induce neovascularization of CV (p < 0.05, R² = 26.8%). These findings suggested that mangosteen peel extract increased β-cell function sensitivity, and effectively suppressed insulin resistance, BMI, and cerebral neovascularization process in type 2 DM rats.

• Journal of the Korean Society of Radiology
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• v.81 no.5
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• pp.1255-1259
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• 2020

We report the ultrasonographic and MRI findings of an infected sclerosing lipogranuloma after scrotal hernioplasty. Sclerosing lipogranuloma is a rare foreign-body reaction of fat tissue, with most cases being associated with the genital and urinary tracts. To the best of our knowledge, MRI findings in sclerosing lipogranuloma in the scrotal sac have not yet been published and this is possibly the first study to report the case of an infected sclerosing lipogranuloma in the English literature.

• Korean Journal of Agricultural Science
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• v.51 no.1
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• pp.1-8
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• 2024

We conducted this research to examine the reducing level of lysine : tryptophan ratios in the diet affected the performance and meat quality of finishing pigs. At the end of the experiment, 144 crossbred finishing pigs (Duroc × [Yorkshire × Landrace]) having an average body weight of 70.6 ± 3.9 kg were randomly assigned to four dietary treatments (9 replications, 4 pigs per pen). The pigs in the 4 treatments were fed diets with different lysine : tryptophan ratios, such as 1 : 0.175, 1 : 0.160, 1 : 0.145, and 1 : 0.130. In considering average daily gain (ADG), average daily feed intake (ADFI), and feed conversion ratio (FCR), the ratio of tryptophan and lysine (Lys : Trp) did not show any significant effect (p > 0.05). Moreover, nutrient digestibility had no significant impact (p > 0.05). However, the decreasing level of tryptophan linearly decreased the back-fat thickness at overall period (p = 0.038) and reduced at week 5 (p = 0.007). Additionally, the lean meat percentage (LMP) showed a tendency to increase at initial (linear effect, p = 0.097) and increased at overall period (linear effect, p = 0.045). Therefore, we suggest that Lys : Trp ratio of 0.130 could enhance the meat quality in finishing pigs.

• Nutrition Research and Practice
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• v.18 no.2
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• pp.180-193
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• 2024

BACKGROUND/OBJECTIVES: Obesity is a major cause of metabolic disorders; to prevent obesity, research is ongoing to develop natural and safe ingredients with few adverse effects. In this study, we determined the anti-obesity effects of Rosa multiflora root extract (KWFD-H01) in 3T3-L1 adipocytes and Sprague-Dawley (SD) rats. MATERIALS/METHODS: The anti-obesity effects of KWFD-H01in 3T3-L1 adipocytes and SD rats were examined using various assays, including Oil Red O staining, gene expression analyses, protein expression analyses, and blood biochemical analyses. RESULTS: KWFD-H01 reduced intracellular lipid accumulation and inhibited the mRNA expression of peroxisome proliferator-activated receptor γ (PPARγ), cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins (C/EBPα), sterol regulatory element-binding transcription factor 1 (SREBP-1c), acetyl-CoA carboxylase (ACC), and fatty acid synthase (FAS) in 3T3-L1 cells. KWFD-H01 also reduced body weight, weight gain, and the levels of triglycerides, total and LDL-cholesterol, glucose, and leptin, while increasing high-density lipoprotein-cholesterol and adiponectin in SD rats. PPARγ, C/EBPα, SREBP-1c, ACC, and FAS protein expression was inhibited in the epididymal fat of SD rats. CONCLUSION: Overall, these results confirm the anti-obesity effects of KWFD-H01 in 3T3-L1 adipocytes and SD rats, indicating their potential as baseline data for developing functional health foods or pharmaceuticals to control obesity.

• Korean Journal of Agricultural Science
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• v.50 no.2
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• pp.295-304
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• 2023

Synbiotics help to improve gut health by promoting the growth of beneficial bacteria while glyconutrients provide a source of energy for the gut bacteria and may also have immunemodulating effects. The aim of the present study was to assess the effect of this combination on fatty acid and meat quality characteristics of growing pigs. In a five-week experiment, 804 growing three-way crossbred ([Landrace × Yorkshire] × Duroc) pigs with an initial body weight of 31.90 ± 2.6 kg on average were assigned to two treatments: 1) CON (basal diet) and 2) TRT1 (basal diet + 0.3% glycozyme [synbiotics and glyconutrient]), each consisting of 402 pigs. The TRT1 groups showed significantly higher values of palmitoleic acid (C16:1), capric acid (C10:0), myristic acid (C14:0), lauric acid (C12:0), elaidic acid (C18:1, t), pentadecylic acid (C15:0), gondoic acid (C20:1), lignoceric acid (C24:0), and omega-6 : omega-3 in fat than the CON groups. Moreover, in the lean tissues of the pig, the levels of C12:0, C14:0, C17:0, and C20:1 were significantly higher in TRT1 than in CON. However, significant differences were not observed after glycozyme addition in pH, water holding capacity, cooking loss, longissimus muscle area, drip loss, meat color, and sensory evaluation parameters. To conclude, the positive results of the fatty acid composition indicate that glycozyme may be an effective pig feed additive.