To understand the effect of prenatal stress on sex-specific changes in embryonic and placental growth, a synthetic glucocorticoid (dexamethasone) was administered intraperitoneally at a dosage of 1 mg/kg body weight (BW) (Dex1) or 10 mg/kg BW (Dex10) to pregnant ICR mice at the gestational days 7.5, 8.5 and 9.5 post coitum (p.c.). Embryos and placentas were then harvested at days 11.5 and 18.5 p.c., and their body weight and size were measured following the determination of sex through PCR using Sry specific primers in tail tissues. As a result, female embryos presented reduced fetal body weight and size in Dex1- and Dex10-treated groups than those of control group at the embryonic day 11.5 p.c. Interestingly, the growth seems to be recovered at day 18.5 as there was no difference in growth between control and dexamethasone treated groups. In the case of males, Dex1 induced a decrease in fetal weight in day 11.5 and this pattern was maintained until day 18.5, whereas their growth was not affected by Dex10 treatment. Placental growth showed similar patterns to fetal growth in both sexes but the extent of reduction was not statistically significant in most cases. Placental weights in Dex1- and Dex10-treated group were decreased significantly in male only. The results imply that the effect of prenatal stress is largely sex dependent due to different strategies for growth and survival in a stressful environment.
1. Objectives This study is purposed to find Lee Je-Ma's thoughts and intention proposed in the ${\ulcorner}$Gyukchigo격치고(格致藁) . 유략(儒略)${\lrcorner}$2. Methods It was researched through comparative and overall study on ${\ulcorner}$Gyukchigo격치고(格致藁) . 유략(儒略)${\lrcorner}$ 3. Results and Conclusions (1) On the assumption of Affairs. Mind. Body' Objects 사심신물(事心身物 ) as the principle of existence and correlation, there are basic dualistic structure such as 'Il(一)' (individual level) and 'Man만(萬)' (universal level) for explanation of ${\ulcorner}$Gyukchigo격치고(格致藁) . 유략(儒略)${\lrcorner}$ (2) Human who easily have individual inclination of mind(private . dissoluteness' idleness' desire) and wickedness (stinginess. extravagance' idleness' fraud) are the being making invidual ethics of behavior by earnestness' intelligence. capability . diligence성혜능동(誠慧能動) and universal ethics by Wisdom' Propriety. Justice. Humanity 지례의인(智禮義仁) through devotion' right . practice' concentration of mind' heart . body . power. (3) Human in the world having individual immanent psychological four element의려담지(意慮擔志) and universal exptessinal 외 four element청시언모(聽視言貌) are under a bias toward wickedness because of inclination of mind. So extending of individual ethics of behavior and completion of universal ethics are essential and indispensable (4) The final aim of human being in the universe is bringing universal ethics of behavior(Wisdom . Propriety' Justice. Humanity청시언모(智禮義仁) to perfection. (5) Devotion right practice concentration성정수일(誠正修一) of mind heart body power의심신력(意心身力) are developmental notions of earn emestness intelligence capability diligence성혜능동(誠慧能動), essential individual for living in the world, and preceding element for moral edification, social behavior and administration of the state.
Underreporting of dietary intake is common and might distort analysis and interpretation of dietary surveys. This study was designed to investigate the degree of underreporting and characterastics of under-reporting group in Korean college female students. Dietary survey of 1-day 24-hour recall method was conducted on 379 college students in Seoul and Chonan areas. Physical activity and life style were aquired from questionnnaires. Underreporting was defined as energy intake(EI) lower than 0.9BMR(based metabolic rate), since EI<0.98BMR is statistically judged as bias in 1-day 24 hour recall. BMR was calculated from Schofield's equation. Proportion of underreporting was 18.7% and it's not so different from one of American or European women. Intake of nutrients except vitamin A by underreporting group was lower than other groups(p<0.001). Proportions of subjects with nutrient intake level less than 75% of Korean RDA were more than 80% in protein, Ca, Fe, vitamin A, riboflavin, niacin, zinc as well as energy. Dietary quality of underreporting group was also worse than other groups. Proportion of subjects less than 3 food groups among 5 food group was higher in underreporting group. The number of foods eaten by underreporting group were also less than those of other groups. BMI and body weight were the largest in underreporting group(p<0.05) and the trial of weight reduction was shown higher trend(p<0.01). Different in PAC and other characteristics between underreporting group and other group were not significant. Not only dietary quantity but also dietary quality were worse in the underreporting group. Furthermore underreporting in college female students seemed to be affected by body weight and concern for weight reduction.
Riccardo Sartoris;Alberto Calandra;Kyung Jin Lee;Tobias Gauss;Valerie Vilgrain;Maxime Ronot
Korean Journal of Radiology
/
v.22
no.8
/
pp.1300-1309
/
2021
Objective: To assess the feasibility and reproducibility of pancreatic surface lobularity (PSL) quantification derived from abdominal computed tomography (CT) in a population of patients free from pancreatic disease. Materials and Methods: This retrospective study included 265 patients free from pancreatic disease who underwent contrast-enhanced abdominal CT between 2017 and 2019. A maximum of 11 individual PSL measurements were performed by two abdominal radiologists (head [5 measurements], body, and tail [3 measurements each]) using dedicated software. The influence of age, body mass index (BMI), and sex on PSL was assessed using the Pearson correlation and repeated measurements. Inter-reader agreement was assessed using the intraclass correlation coefficient (ICC) and Bland Altman (BA) plots. Results: CT images of 15 (6%) patients could not be analyzed. A total of 2750 measurements were performed in the remaining 250 patients (143 male [57%], mean age 45 years [range, 18-91]), and 2237 (81%) values were obtained in the head 951/1250 (76%), body 609/750 (81%), and tail 677/750 (90%). The mean ± standard deviation PSL was 6.53 ± 1.37. The mean PSL was significantly higher in male than in female (6.89 ± 1.30 vs. 6.06 ± 1.31, respectively, p < 0.001). PSL gradually increased with age (r = 0.32, p < 0.001) and BMI (r = 0.32, p < 0.001). Inter-reader agreement was excellent (ICC 0.82 [95% confidence interval 0.72-0.85], with a BA bias of 0.30 and 95% limits of agreement of -1.29 and 1.89). Conclusion: CT-based PSL quantification is feasible with a high success rate and inter-reader agreement in subjects free from pancreatic disease. Significant variations were observed according to sex, age, and BMI. This study provides a reference for future studies.
Journal of the Korea Fashion and Costume Design Association
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v.12
no.2
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pp.55-65
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2010
The present study purposed to compare formative expression between the fashion of the end of 19th century - early 20th century and that of the 21st century which were influenced by art nouveau and art deco. For this purpose, we analyzed contents in literature, Internet, etc.,. According to the results of this study, the formative expression of art nouveau were divided into continuous movement, optical illusion and decorative expression. Continuous movement was used to express fancy and soft images in the end of 19th century, and to express images giving the feeling of speed and tension in the 21st century. Optical illusion was expressed by the movement the thin and soft materials with the body movement and the movement of excessive frills adornment. And in movement produced using thin and soft materials and by the bias cutting method in the 21st century. Decorative expression was expressed as fantasy and decadent image in the end of 19th century and as mild passionate and modern image with color combination in the 21st century. The formative expression of art deco were divided into visual simplicity, contrastive loudness, and functional expression. Visual simplicity was expressed as a boyish image in the early of 20th century, but as a complex expression combining simplicity and femininity in the 21st century. Contrastive loudness was expressed by using colors both in the early of 20th century and 21st century. Functional expression was reinforced through the lightening of design and materials in the early of 20th century, but through using bias cutting high tech materials in the 21st century.
Weight-controlling can be supported by a proper prescription of energy intake. The individual energy requirement is usually determined through resting energy expenditure (REE) and physical activity. Because REE contributes to 60-70% of daily energy expenditure, the assessment of REE is very important. REE is often predicted using various equations, which are usually based on the body weight, height, age, gender, and so on. The aim of this study is to validate the published predictive equations for resting energy expenditure in 76 normal weight and 52 obese Korean children and adolescents in the 7-18 years old age group. The open-circuit indirect calorimetry using a ventilated hood system was used to measure REE. Sixteen REE predictive equations were included, which were based on weight and/or height of children and adolescents, or which were commonly used in clinical settings despite its use based on adults. The accuracy of the equations was evaluated on bias, RMSPE, and percentage of accurate prediction. The means of age and height were not significantly different among the groups. Weight and BMI were significantly higher in obese group (64.0 kg, $25.9kg/m^2$) than in the non-obese group (44.8 kg, $19.0kg/m^2$). For the obese group, the Molnar, Mifflin, Liu, and Harris-Benedict equations provided the accurate predictions of > 70% (87%, 79% 77%, and 73%, respectively). On the other hand, for non-obese group, only the Molnar equation had a high level of accuracy (bias of 0.6%, RMSPE of 90.4 kcal/d, and accurate prediction of 72%). The accurate prediction of the Schofield (W/WH), WHO (W/WH), and Henry (W/WH) equations was less than 60% for all groups. Our results showed that the Molnar equation appears to be the most accurate and precise for both the non-obese and the obese groups. This equation might be useful for clinical professionals when calculating energy needs in Korean children and adolescents.
We examine large-scale environmental effects on the formation and the mass growth of dark matter halos. To facilitate this, we constructed dark matter halo merger trees from a cosmological N-body simulation, which enabled us to trace the merger information and the assembly history of individual halos. In fact, since the massive halos are more likely to be distributed in denser regions than in less dense regions (Mo & White, 1996), the large-scale environment dependence of the properties of halos can be partly originated from the halo mass effect. In order to avoid such contamination, caused by the mass dependence of halo properties, we carefully measured the local overdensity as the indicator of large-scale environment, which was calculated to be as independent of halo mass as possible. Small halos (${\sim}10^{11-12}M_{\odot}$), which usually host isolated single galaxies, show a notable difference on the formation time of galaxies depending on their large-scale environments, which reconfirms halo assembly bias (Gao & White, 2007). Furthermore, we investigate how this environmental effect on small halos is correlated with the mass assembly history of galaxies by using our semi-analytic model. We found that assembly bias in small halos does not have significant effects on the formation time or on the star formation history of galaxies residing in those halos except for the individual stellar mass of galaxies at z = 0. On average, isolated galaxies in high-density regions tend to be slightly more massive than those in low-density regions. Although the observational data from the current galaxy surveys is not yet sufficient for testing this prediction, future galaxy surveys will be able to explore these small galaxies more thoroughly.
This study aimed to investigate the effectiveness of carotenoid supplementation on the performance, egg quality, and immunity of laying hens using a meta-analysis approach. The database was searched using Google Scholar and Scopus, from 2012 to 2022. The literature was published in English. 47 Articles were selected for meta-analysis. Analyses were performed using the Open Meta-analyst for Ecology and Evolution (OpenMEE) software. The heterogeneity and data validation against publication bias were analyzed using JASP 0.16.2 software. Overall, the results showed that carotenoid supplementation improved feed intake by 0.32 g/day/hen [95% confidence interval (CI)=0.02 to 0.61], final body weight by 0.33 g/hen (95% CI=0.05 to 0.60), egg production by 0.38% (95% CI=0.14 to 0.63), egg weight by 0.29 g (95% CI=0.09 to 0.5), yolk colour by 2.11 (95% CI=1.71 to 2.51), Haugh unit (HU) by 0.26 (95% CI=0.11 to 0.42), yolk carotenoids by 1.17 ㎍/kg (95% CI=0.59 to 1.75), immunoglobulin A (IgA) by 0.74 mg/L (95% CI=0.18 to 1.29), and lower yolk cholesterol by -0.38 mg/g (95% CI=-0.59 to -0.16). Feed conversion ratio (FCR), eggshell thickness, and white blood cells were unaffected by the application of carotenoids. The heterogeneity analysis showed variability in all studies (<0.05). In conclusion, carotenoid supplementation can elevate productivity, enhance egg quality, and improve immunity. However, based on Kendall's test, there was a publication bias in several parameters, namely FCR, egg weight, HU, yolk carotenoids, and IgA.
Objective: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns. Materials and Methods: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords. This study incorporated literature that compared RFA and MWA for benign thyroid nodules. The primary outcome was the volume reduction ratio (VRR) from baseline to follow-up. Secondary outcomes were symptom score, cosmetic score, ablation time, major complications rate, hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. We used Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) tool to assess the risk of bias in the included studies. We employed random effects models to analyze the standardized mean difference (SMD) and odds ratio for the presentation of outcomes. Results: Nine studies with 2707 nodules were included. The results of our meta-analysis indicated similar efficacy between RFA and MWA in terms of VRR during the 1 (SMD 0.06; 95% confidence interval [CI]: -0.13 to 0.26; P = 0.52) and 3 (SMD 0.11; 95% CI: -0.03 to 0.25; P = 0.12) months of follow-up. VRR was significantly higher in RFA than in MWA at the 6 (SMD 0.25; 95% CI: 0.06-0.43; P = 0.008) and 12 month of follow-up (SMD 0.38; 95% CI: 0.17 to 0.59; P < 0.001). There were no significant differences between RFA and MWA in symptom scores, cosmetic scores, or the incidence of complications, including hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. Conclusion: RFA showed a higher VRR than MWA at 6 and 12-month follow-ups, with a comparable safety profile.
De Carvalho, Gleidson Giordano Pinto;Garcia, Rasmo;Vieira Pires, Aureliano Jose;Silva, Roberio Rodrigues;Detmann, Edenio;Oliveira, Ronaldo Lopes;Ribeiro, Leandro Sampaio Oliveira
Asian-Australasian Journal of Animal Sciences
/
v.26
no.1
/
pp.65-71
/
2013
Two digestion trials, one with sheep and another with goats, were conducted to evaluate the long-term bias (LTB) of the indigestible dry matter (iDM), indigestible neutral detergent fiber (iNDF) and indigestible acid detergent fiber (iADF) internal markers. The study used eight Santa In$\hat{e}$s castrated male sheep (average body weight of 16.6 kg) distributed in two $4{\times}4$ Latin squares and eight Saanen castrated male goats (average body weight of 22.6 kg) distributed in two $4{\times}4$ Latin squares. The experiments were conducted simultaneously, and the animals were housed in 1.2 $m^2$ individual pens with wood-battened floors equipped with individual feeders and drinkers. The animals received isonitrogenous diets that were offered ad libitum and contained 14% crude protein and 70% sugar cane (with 0, 0.75, 1.5 or 2.25% CaO, in natural matter percentage), corrected with 1% urea and 30% concentrate. The experiment consisted of four experimental periods of 14 d each, with the feed, leftovers and feces sampled on the last four days of each period. The marker concentrations in the feed, leftovers and fecal samples were estimated by an in situ ruminal incubation procedure with a duration 240 h. The relationship between the intake and excretion of the markers was obtained by adjusting a simple linear regression model, independently from the treatment (diets) fixed effects and Latin squares. For both the sheep and goats, a complete recovery of the iDM and iNDF markers was observed (p>0.05), indicating the absence of LTB for these markers. However, the iADF was not completely recovered, exhibiting an LTB of -9.12% (p<0.05) in the sheep evaluation and -3.02% (p<0.05) in the goat evaluation.
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