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Association between Interleukin-1α Polymorphism -889C/T and Sasang Constitution in Korean Obese Women (한국 비만 여성에서 인터루킨-1 알파 다형성 -889C/T와 사상체질과의 연관성)

  • Song, Jeong-Seop;Kwon, Young-Dal;Kim, Seon-Jong;Lee, Sang-Gyu;Yeom, Seung-Ryong;Song, Yong-Sun
    • Journal of Korean Medicine Rehabilitation
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    • v.15 no.1
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    • pp.67-75
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    • 2005
  • 목 적 : 면역 세포에서 주로 생성되는 사이토카인인 인터루킨-1 (interleukin-1)은 다양한 신경내분비계와 대사 기능에 영향을 미치며, 비만인의 말초혈액 단핵구에서 증가하는 경향이 있는 것으로 연구보고 되고 있다. 본 연구의 목적은 $IL-1{\alpha}$ 다형성과 사상체질이 비만과 관련이 있는지를 조사하는데 있다. 연구방법 : 본 연구에서는 현저한 체질량지수 (body mass index, BMI) 다양성을 보이는 건강한 한국 여성 182명을 대상으로 $IL-1{\alpha}$ 유전자형을 분석하였다. 결 과 : T 대립 유전자는 BMI 감소와 관련이 있었다. BMI $27-30kg/m^2$ 그룹(group III)에서 T 대립유전자의 빈도는 $25kg/m^2$ 미만의 그룹(group I)에 비하여 유의하게 감소하였다 (odds ratio, OR, 0.141; 0.25% CI, 0.04-0.54). 더욱이 태음인 여성에서 $IL-1{\alpha}$ T 대립유전자의 빈도가 normal group에 비하여 overweight group (BMI $27-29kg/m^2$)에서 명확하게 감소하였다 (OR, 0.139; 95% CI, 0.04-0.54). 결 론 : 본 연구에서 175명의 체질분석결과 $BMI{\geq}25$인 군들의 태음인의 빈도가 높았으며, BMI는 CC genotype를 가진 사람에서보다 CT+TT genotype를 가진 사람에게서 더 낮았다. 태음인에서 동형접합 또는 이형접합 T 대립유전자가 $BMI{\geq}25$인 군에서 유의하게 감소하였다. 이상의 결과는 한국 여성에서 $IL-1{\alpha}$ 유전자 조절부위에 위치한 -889C/T 다형성과 비만 및 사상체질의 관련되는 것을 의미한다.

Body Esteem, Body Figure Discrepancy and Depression in Women College Students (여대생의 신체존중감, 신체상 불일치 및 우울)

  • Lee Kyue-Un;Kim Eun-Ju;Yom Young-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.2
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    • pp.206-214
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    • 2005
  • Purpose: The purpose of this study was to identify body esteem, body figure discrepancy and depression in women college students. Method: The data were collected during April and May, 2004 using a questionnaire. The participants were 364 women college students attending universities in Seoul and Gangwon-Do. Results: The BMI for under weight, normal weight and overweight for the college women were 49.2%, 48.3%, 2.5% respectively. But 52.6% of the students perceived themselves as obese and only 11.5% described themselves as being 'thin'. The mean scores for BMI, body esteem, body figure discrepancy and depression were $20.11{\pm}2.20$, $2.36{\pm}.79$, $1.07{\pm}.58$ and $1.20{\pm}.48$ respectively. Significant difference was found in body esteem score (F=26.389 p<.0001) and body figure discrepancy (F=64.167, p<.0001) according to BMI scores. There were negative correlations between body esteem and body figure discrepancy (r=-.582, p=.0001), between body esteem and depression (r=-.120, p=.028), between body esteem and BMI (r=-.422, p=.0001), and a positive correlation between body figure discrepancy and BMI (r=.630, p=.0001). Factors such as body figure discrepancy, BMI and depression explained 36.7% of the valiance in students' body esteem. Conclusion: This study suggests that an intervention program is necessary for women college students to increase their body esteem.

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Body Mass Index, Anthropometric Factors, and Food and Nutrient Intakes of Korean Middle-Aged Males by Year : Based on 2001~2011 Korea National Health and Nutrition Examination Survey (KNHANES) (한국 중년 남성의 연도별 체질량지수, 신체계측치, 식품 및 영양소 섭취량 변화 : 국민건강영양조사 결과(2001~2011))

  • Choi, Soon-Nam;Jho, Kwang-Hyun;Chung, Nam-Yong
    • Journal of the Korean Dietetic Association
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    • v.22 no.2
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    • pp.88-105
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    • 2016
  • This study investigated anthropometric and biochemical characteristics, food and nutrient intakes, and changes in body mass index (BMI) of Korean middle age men (40~49 yrs). Data on BMI, anthropometric (height, weight, waist circumference, body mass index, blood pressure), and biochemical (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, hemoglobin, GOT, GPT) characteristics, food and nutrients intakes, nutrient density, and index of nutrient quality were obtained from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES, 2001, 2005, 2011). Subjects were divided into three groups by year. Weight, BMI, and hemoglobin increased significantly by year. All anthropometric factors except height showed a positive relation with BMI by year. Consumption of barley, chinese noodle, confections, soybean milk, egg, ice cream, pizza, fried foods, banana, coffee, and raw rice wine increased significantly by year. Intake ratios of nutrients except water and fiber were over 100% of KDRI generally. INQ according to intakes of protein, calcium, phosphorus, iron, vitamin A, thiamine, riboflavin, and niacin per 1,000 kcal increased significantly by year. Distribution of BMI status of subjects showed a significant difference by exercise. The findings of the present study show that BMI of subjects increased by year, and intakes of all nutrients except calcium and riboflavin showed aspects of overnutrition by year. Intakes of fruits decreased while intakes of raw rice wine and coffee increased by year. Therefore, practical and systematic nutrition programs are required to maintain optimum BMI and appropriate intakes of nutrients to maintain a desirable lifestyle and improve dietary life.

A Study on the Serum Lipid Levels and Related Factors among Women in a Rural Community (일부 농촌지역 여성들의 혈청지질치와 관련요인에 대한 조사)

  • Lim, Jeong-Whan;Cho, Young-Chae;Lee, Dong-Bae
    • Journal of agricultural medicine and community health
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    • v.22 no.1
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    • pp.27-34
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    • 1997
  • This study was performed to offer the fundamental data for preventing and controlling the cardiovascular diseases of rural community women. The number of 168 women aged 40 to 50s who live in Kumsan-gun, Chungnam were selected for analysis after medical examination by a Kumsan-gun health center during the period of November to December in 1996. Total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), blood pressure(BP), degree of obesity(BMI) and atherosclerosis index(AI) were measured and relation between these physical measurements to serum lipid levels were studied. The results were as follows; 1. Mean TC level, TG level, BP, BMI and AI were significantly increased with advancing age. 2. Mean TC level, TG level, BMI and AI of borderline BP group and hypertension group were significantly increased than those of normal BP group. 3. Mean TC level, TG level and AI of obesity group were significantly increased than those of normal BMI group. 4. Simple correlation analysis showed that the positive correlation between TC, TG, BP, BMI and AI, but the level of HDL-C was negative correlation with TG and AI. 5. In multiple regression analysis taking HDL-C level as the dependent variable and TG, TC, BP, BMI, Age AI as the independent variable, AI, TG, BMI, TC were significantly related to HDL-C.

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The influence of gonadotropin-releasing hormone agonists on anthropometric change in girls with central precocious puberty

  • Yoon, Jong Wan;Park, Hyun A;Lee, Jieun;Kim, Jae Hyun
    • Clinical and Experimental Pediatrics
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    • v.60 no.12
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    • pp.395-402
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    • 2017
  • Purpose: The potential effect of gonadotropin-releasing hormone agonist (GnRHa) treatment on the weight of girls with central precocious puberty (CPP) remains a controversy. We investigated anthropometric changes during and after GnRHa treatment among girls with CPP. Methods: This retrospective study evaluated data from 127 girls with CPP who received GnRHa treatment for ${\geq}2years$. Height, weight, and body mass index (BMI) values were compared at the baseline (visit 1), after 1 year of GnRHa treatment (visit 2), the end of GnRHa treatment (visit 3), and 6-12 months after GnRHa discontinuation (visit 4). Results: The height z score for chronological age (CA) increased continuously between visit 1 and visit 4. No significant differences were observed in BMI z score for CA between visits 1 and 4. However, an increasing trend in the BMI z score for bone age (BA) was observed between visits 1 and 4. The numbers of participants who were of normal weight, overweight, and obese were 97, 22, and 8, respectively, at visit 1, compared to 100, 16, and 11, respectively, at visit 4 (P=0.48). Conclusion: Among girls with CPP, the overall BMI z score for CA did not change significantly during or after GnRHa treatment discontinuation, regardless of their BMI status at visit 1. However, the BMI z score for BA showed an increasing trend during GnRHa treatment and a decreasing trend after discontinuation. Therefore, long-term follow-up of BMI changes among girls with CPP is required until they attain adult height.

Longitudinal Data Analysis for School-aged Adolescents' Obesity Rates across the States (미국 청소년의 비만에 관한 종단적 분석)

  • Kim, TaeEung;Kim, Jongho;Hwang, Sunhwan
    • The Journal of the Korea Contents Association
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    • v.16 no.8
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    • pp.743-755
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    • 2016
  • The objectives of this research is to examine: 1) how the rates of adolescents' BMI change over time in terms of the state level; and 2) development difference in the state level of BMI in terms of children's obesogenic behaviors from 1999 to 2011. Data were drawn from the 1999-2011 Youth Risk Behavior Survey in the United States (N=260, 293, grades 9-12, and 27 states). Ordinary least squares regression and hierarchical linear modeling were utilized to capture a longitudinal time effect of school-aged adolescents' obesity rates across the states, controlling for demographics and nutrition- and physical activity-related behaviors. The state's level of children's BMI percentile was significantly associated with longitudinal time. Longitudinal time effect across the states appears to play an important factor associated with children's decrease of BMI percentile. Therefore the states' implementation of physical activity and nutritional policies seems to be effective for preventing and reducing childhood obesity during last decade. More attention should focus on enforcing the policy and overcoming current barriers in order to minimize children's obesogenic factor.

A Study on the Health and Nutritional Status of Bus Drivers in the Masan Area (마산지역 시내버스 운전자의 건강상태 및 영양소 섭취실태)

  • 윤현숙;김기련
    • Korean Journal of Community Nutrition
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    • v.7 no.3
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    • pp.316-326
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    • 2002
  • This study was carried out on 178 bus drivers in the Masan area to investigate their health and nutritional status. THe nutritional status of the subjects was surveyed using a self-administered questionnaire, and blood analyses were conducted through annual health examinations in June, 1999. The results were as fellows: About 51% were classified as normal, 33% as health-concerned, and 17% as disease-suspected. The levels of total seam cholesterol were significantly higher in the over 20 year group (194.64 $\pm$ 41.42 mg/dl) than in the under 10 year group (175,00 $\pm$ 31.33 mg/dl) with respect to the length of their driving careers. Systolic blood pressure (SBP) was significantly higher in the 51 to 60 age group than in the other groups (p < 0.05) . The total seam cholesterol increased with increasing age (p < 0.001), and SBP increased with increasing Body Mass Index (BMI) (p < 0.001). Diastolic blood pressure (DBP), total cholesterol (p < 0.01), hemoglobin (p < 0.05) and glutamate-pyruvate-aminotransferase (GPT) (p < 0.05) were significantly higher in the BMI of over 20, than in the BMI under 20. The GPT was significantly higher in the BMI over 25 than in the BMI under 25. In The mean daily energy intake was 1912.7 kcal (76.5% of the RDA) ultra the protein intake was 74.3 g (106.2% or the RDA). Compared with the recommended allowance, the energy, calcium, thiamin, and riboflavin intakes were below, and the Fe, vitamin A, vitamin C intakes were above the Korean RDA. The average carbohydrate, protein, fat ratio of energy intake was 66 : 15 : 19, respectively. The length of their driving careers had a positive correlation with their ages and total serum cholesterol levels, and their ages had a positive correlation with their blood pressures, total seam cholesterol and hemoglobin levels and BMI. Their BMI had a positive correlation with their ages, blood pressures, total serum cholesterol, hemoglobin, GPT and GOT levels. The results of this study indicate that bus drivers needed regular exercise, and control of their body weights to prevent chronic diseases, and that their health status should be monitored as the length of their driving careers and ages increase.

Concern about Body Weight and Dietary Intake by BMI Distribution in Korean University Students

  • Lee, Mi-Young;Lee, Jeong-Hee;Cheong, Sun-Hee;Chang, Kyung-Ja
    • Journal of Community Nutrition
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    • v.5 no.3
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    • pp.141-150
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    • 2003
  • The purpose of the study was to investigate attitude about self-weight reduction and dietary intakes by body mass index (BMI) of university students. The subjects were Korean university students (male: 1,024, female: 1,575) who were participating in a nutritional education class via the internet. This survey was carried out using a self-administered questionnaire. The questionnaire included items about demographic characteristics, nutrient intakes, health-related lifestyles, dietary behaviors, body images and diet experiences. As for prevalence of obesity, 3.2% of male subjects were underweight, 64.2% were normal weight, 20.8% were overweight, and 11.8% were obese. In female subjects, 25.8% were underweight, 67.1 % were normal weight, 5.3% were overweight, and 1.7% were obese. Distribution of obesity by BMI was significantly different between male and female subjects. There was a significant difference in perceptions of body weight between male and female subjects. The female subjects were more likely to perceive themselves as overweight. As for weight reduction, the higher BMI was, the more weight reduction was tried in both male and female subjects. As for average daily intakes for energy and 11 nutrients, most nutrient intakes were not significantly different by distribution of BMI. However, obese subgroup showed the lowest nutrient intakes compared to other subgroups. As BMI increased, mean adequacy ratio (MAR) significantly decreased. Therefore, nutritional education via the internet is necessary for university students to establish physically and mentally optimal health condition through nutritional intervention.

A Study on Anthropometric Data of 5 th Grade Students II. Comparisons Between Underweight and Overweight Group by BMI (국교 5년생의 성장발달에 관한 조사 연구 II. BMI 에 따른 저체중과 과체중의 요인분석)

  • 문현경
    • Journal of Nutrition and Health
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    • v.20 no.6
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    • pp.405-410
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    • 1987
  • Study population was described at the previously published paper(23). Body Mass Index of 10751, 5th grade students from nation-wide were calculated . From this distribution lowest 10% and highest 10% were selected as group 1 and group 5, respectively. In this paper, between group 1 and group 5 anthropometric data, demographic data and other health related factors were compared. 1) Using Japanese criteria for obesity, the prevalence for obesity at 5 th grade was 5.8% at nation wide and 7.8% at urban area. 2) The proportion of students who skipped breakfasts everyday was 5.8% of whole student surveyed and 8.4% for group 5. The proportion of students who took medicine for health was 29.4% for group and 22.5% for group 5. 3) The students who are at group 5 had larger height and weight velocity than other groups. Group 5 had large increase of BMI by increasing grade, but group 1 had almost no change. 4) In physical fitness examination, group 3 who mean BMI was in the highest class than other groups 5 was in low class.

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Prevalence of overweight and obesity, and dieting attitudes among Caucasian and African American college students in Eastern North carolina: A cross-sectional survey

  • Sira, Natalia;Pawlak, Roman
    • Nutrition Research and Practice
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    • v.4 no.1
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    • pp.36-42
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    • 2010
  • A cross-sectional survey was used to investigate the rates of overweight and obesity (BMI$\geq$25), and eating attitudes among college students. Data were collected at a large southeastern university. Adolescents (ages 18-25) self-reported weight and height (to calculate BMI), and, in addition to demographic information, completed the eating attitudes (EAT 26) scale to assess dieting tendencies. Significance of the mean BMI differences between gender and ethnic background were assessed by one-way analysis of variance (one-way ANOVA). Chi-square was used to determine whether the rate of those with BMI$\geq$25 between gender and ethnic background was statistically significant. While 52.7% of the students' BMI were within the normal weight category, 15.2% were underweight, 21.3% were overweight, and 10.8% were obese. The rate of BMI$\geq$25 differed by gender and ethnicity, with males and African Americans having higher rates. About 12 % of the participants reported disturbed eating behavior, which is lower than previously reported. Even so, results support the generally held belief that disturbed eating attitudes and unhealthy dieting are common among college students, especially among females. At the same time, disturbed eating attitudes are not just the domain of young female students; about 10% of college males reported disturbed eating attitudes. Findings of this study call for obesity prevention/intervention and lifestyle modification outreach programs among college students. Weight status and unhealthy eating behaviors of college. students should be a concern to health care professionals. While obese young adults will likely remain obese throughout their adult life, excessive dieting among students, which is linked to eating disorders and other health hazards, does not provide healthy and adequate alternatives for maintaining a normal BMI. Implications for obesity prevention programs are discussed.