• 제목/요약/키워드: blood. diabetes.

검색결과 1,691건 처리시간 0.028초

Streptozotocin 유발 당뇨 백서에 상엽 지각(桑葉 枳殼) 혼합물의 항당뇨 및 혈관탄성개선 효과 (The Anti-diabetes and Vasoelasticity Effects of Mori Folium and Aurantii Fructus in Streptozotocin Induced Type II Diabetes Mellitus Model)

  • 박정섭;박종형;전찬용;최유경;황귀서;김동우
    • 대한한방내과학회지
    • /
    • 제28권3호
    • /
    • pp.544-559
    • /
    • 2007
  • Objectives : This study was designed to evaluate the anti-diabetes and vasoelasticity effects of Mori Folium and Aurantii Fructus in streptozotocin-induced type II diabetes mellitus model. Methods : The anti-diabetic effect of Mori Folium and Aurantii Fructus on rats induced with diabetes by streptozotocin was investigated through analyses of changes in body weight, blood glucose, urine volume of rats, viability of human umbilical vein endothelial cells(HUVECs), and elasticity of descending thoracic aorta in rats. The subjects in this study were divided into four groups(n=15): a normal group without any treatment (Con), a normal group with Mori Folium and Aurantii Fructus treatment(Con+P), a diabetes group induced by streptozotocin(STZ), and a Mori Folium and Aurantii Fructus treatment group under diabetes induced by streptozotocin(STZ+P). Rats were administered streptozotocin to induce diabetes. Results : The study showed that Mori Folium and Aurantii Fructus significantly reduced highly increased blood glucose levels(p<0.01) and prevented the diabetic rats from weight loss(p<0.01) and polyurea(p<0.05), Mori Folium and Aurantii Fructus also recovered decreased viability of HUVECs(p<0.01) and damaged elasticity of aorta induced by the streptozotocin (p<0.01). Conclusions: It was concluded from the results that Mori Folium and Aurantii Fructus have a distinct anti-diabetes effect and they also prevent damage of blood vessel induced by diabetes. resulting in prevention of cardiovascular diseases ascribed to diabetes.

  • PDF

자가혈당 측정결과기반 당뇨교육프로그램이 제2형 당뇨병환자의 혈당조절에 미치는 효과 (Effect of Self-Monitoring of Blood Glucose Based Diabetes Self-Management Education on Glycemic Control in Type 2 Diabetes)

  • 심강희;황문숙
    • 한국간호교육학회지
    • /
    • 제19권2호
    • /
    • pp.127-136
    • /
    • 2013
  • Purpose: The aim of the study was to evaluate the effect of self-monitoring of blood glucose (SMBG)-based Diabetes Self-Management Education (DSME) on glycemic control in type 2 diabetes. Methods: This study was designed to compare changes in glycemic control over 12months in SMBG-based DSME group (n=65) versus control group (n=65). Data were obtained from medical records type 2 diabetic patients treated with oral antidiabetic agents and above HbA1c 7.0% from June 2006 to August 2008. All participants completed DSME defined as informational intervention of lifestyle habits and reinforcement of educational Monthly News letter delivered by the diabetes nurse educator. SMBG-based DSME group requested to measure blood glucose 7 times a day for a week and to record their diary and received counseling with a focus on diet and lifestyle during the education. Assessments were conducted baseline, 3, 6 and 12 months. HbA1c was used as an index of glycemic control. Results: 12 months later, the level of HbA1c was reduced by $1.28{\pm}1.68%$ in experimental group and $0.49{\pm}1.05%$ in the control group. We found a significant effect of $Time^*$ Group interaction (p=.013). Conclusion: SMBG-based DSME for patients with type 2 diabetes with oral antidiabetic agents was effective in improving glycemic control and maintaining long-term glycemic control.

The Relationship between Alcohol Consumption and Diabetes in Korean Adults

  • Gi Tae Kim;Jae Woong Sull
    • 대한의생명과학회지
    • /
    • 제29권3호
    • /
    • pp.159-167
    • /
    • 2023
  • The prevalence of diabetes continues to increase worldwide, and the problem is also important in Korea, and about 14% of Korean adults have diabetes. Alcohol consumptions are increasing rapidly around the world and are recognized as one of the major problems in the country. Alcohol consumption is an environmental factor previously known to be associated with the risk of developing diabetes. Alcohol consumption can cause problems in the endocrine system and gastrointestinal function, and oxidative stress of acetaldehyde, an ethanol metabolite, can damage beta cells in the pancreas. In the present study, we found the effect of alcohol intake on fasting blood sugar and the difference between men and women in the risk of diabetes according to alcohol intake. In men, the high-drinking group had a higher risk of diabetes than the non-drinking group (OR, 1.41; P=0.058). In women, the Moderate-drinking group had a lower risk of diabetes compared to the non-drinking group (OR, 0.42; P=0.039). The high-drinking group had a higher risk of diabetes than the non-drinking group (OR, 2.97; P=0.034). The group that consumed more than the WHO's daily alcohol intake risk standard tended to have a higher risk of diabetes than the group that did not (OR, 5.48; P=0.001). This study suggest that moderate alcohol consumption reduce the risk of developing diabetes, and high alcohol consumption increase the risk of developing diabetes.

휴대폰 문자메시지 교육이 제2형 당뇨병환자의 공복혈당과 자가관리에 미치는 효과 (Fasting Blood Sugar and Adherence to Diabetes Control Recommendation : Impact of Education Using Short Messaging Service of Cellular Phone)

  • 김희승
    • Journal of Korean Biological Nursing Science
    • /
    • 제5권2호
    • /
    • pp.13-19
    • /
    • 2003
  • Purpose : The purpose of this study was to investigate the effects of the education using short messaging service(SMS) on fasting blood sugar(FBS) and diabetes adherence. Method : Forty-five diabetic patients being assessed pre and post intervention was used to assess the effectiveness of the education. Participants were requested to input the FBS and 2 hours post-prandial blood sugar everyday in http://www.biodang.com by cellular phone or wire Internet. The goal of the education was to lower FBS and keep diabetes adherence. The education was applied to the for 12 weeks. The education consisted of continuous education and reinforcement of diet, exercise, medication adjustment, as well as frequent self-monitoring of blood glucose levels. The education performed weekly. All medication adjustments were communicated to the participants' doctor. FBS and diabetes adherence were measured before and after the education. Results : The education using SMS of cellular phone had decrease FBS and increase oral medication taking, exercise, foot care, and hypoglycemia preparation adherence.

  • PDF

Management of Diabetes from HbA1c Test

  • Park, Cheolin;Kim, Cheol-Hoe;Lee, Jae-Sik
    • 대한임상검사과학회지
    • /
    • 제42권3호
    • /
    • pp.125-128
    • /
    • 2010
  • HbA1c test measures the amount of glycated hemoglobin in blood. HbA1c shows the average of blood glucose levels for the past three months, this is a better indicator of how overall diabetes is doing. HbA1c gives a much better idea of how the body is breaking down the glucose. Therefore, this HbA1c is very important tool for maintaining normal glucose levels for pre-and diabetic patients. Total 408 participants were tested HbA1c voluntarily from Chosunilbo Health Expo (8th~11th, July 2010). Through this small-scaled direct HbA1c, about 54.7% (207 out of 408) was shown glucose tolerance and diabetes. However, 61 from 157 participants who were shown under 6.9% HbA1c (normal and pre-diabetic stage) are taking only antidiabetic drugs to maintain a normal blood glucose. Regular HbA1c test can bring an important management and awareness about controlling blood sugar level and prevention of diabetic complications.

  • PDF

유.무선 인터넷을 이용한 제2형 당뇨형환자 가정에서의 혈당 입력 (Computer Input Frequency of Blood Glucose Self Testing in Type 2 Diabetic Patients)

  • 김희승
    • 지역사회간호학회지
    • /
    • 제15권1호
    • /
    • pp.29-35
    • /
    • 2004
  • Purpose: The purpose of this study was to investigate the computer input frequency of blood glucose self testing in type2 diabetic patients, for three months. Method: 39 participants were recruited from the endocrinology outpatient department of a tertiary care hospital in an urban city. The computer input frequencies were measured by patients' log in and input of http://www.biodang.com. Glycosylated haemoglobin was determined by a high performance liquid chromatography technique and fasting blood glucose was analyzed by the glucose oxidase method. Diabetes knowledge was measured by a 19 item diabetes knowledge test. Results: The computer input frequency of before breakfast blood glucose was 33.5 for three months. The total blood glucose input frequency tended to be lower in female, aged patients, middle school graduates, those who have no spouse and job, those who have no insulin treatment, obese subjects, and hyperglycemia patients, than in their counterparts. The diabetic knowledge was positively correlated with the computer input frequency of blood glucose self testing. Conclusion: An educational program should be developed to increase the computer input frequency of blood glucose self testing in type2 diabetic patients.

  • PDF

표고버섯 헤미셀룰로즈의 식이가 쥐의 혈당과 콜레스테롤 함량에 미치는 영향 (Dietary Effect of Hemicellulose from Shiitake Mushroom(Lentinus edodes) on Blood Glucose and Cholesterol Content in Rats)

  • 김순동;김미향;이명예
    • 동아시아식생활학회지
    • /
    • 제14권3호
    • /
    • pp.243-250
    • /
    • 2004
  • The effect of hemicellulose extracted from Shiitake mushroom(Lentinus edodes) on the level of blood sugar and cholesterol in the diabetes-induced rat by streptozotocin(STZ) was investigated. The yield of hemicellulose by extraction process of 5% salt extraction, preparation of alcohol insoluble substance, IN KOH extraction, acid precipitation(pH 3.0), and dialysis was 9.24%. The experimental plots divided to 1% cellulose group(control), 0.5% hemicellulose group(H-l) and 1% hemicellulose group(H-2). The groups were fed for 6 weeks, then continuously fed for 1 week after induction of diabetes by STZ. Feed intakes, weight gain and feed efficiency of the each groups were not significantly different, while water intakes and liver weight of H-2 group were lower than those of control and H-l group. Weight of liver in the H-2 group was significantly lower than those of control and H-l groups. The amounts of feces were 0.32 g/day in the control group, 0.43∼0.44 g/day in the H-l and H-2 groups, while the amounts of urine were 15.28 mL/day in the control group, 10.83∼11.20 mL/day in the H-l and H-2 groups. The content of blood glucose before diabetes induction(fed for 3∼5 weeks) was 111.2-132.6 mg/dL in the control group, not significantly different from others; After diabetes induction, however, the contents were 212.8 mg/dL in the control group, 140.0-144.0 mg/dL in the H-l and H-2 groups, which showed significant difference. Urine glucose contents of H-2 group before and after diabetes induction were lower than those of control and H-l groups. There was no significant difference in the content of neutral lipid between each groups. Total cholesterol contents were 101.6 mg/dL in the control group, 56.∼64.0 mg/dL in the hemicellulose groups. HDL-cholesterol content and atherogenic index of hemicellulose groups were lower than those of control group, respectively. In conclusion, the hemicellulose extracted from Shiitake mushroom represented improving and preventing effects for diabetes.

  • PDF

임신성 당뇨 임부의 혈당조절을 위한 포괄적인 생활양식조절 코칭 프로그램의 효과 (Effects of a Coaching Program on Comprehensive Lifestyle Modification for Women with Gestational Diabetes Mellitus)

  • 고정미;이종경
    • 대한간호학회지
    • /
    • 제44권6호
    • /
    • pp.672-681
    • /
    • 2014
  • Purpose: The purpose of this study was to investigate the effects of using a Coaching Program on Comprehensive Lifestyle Modification with pregnant women who have gestational diabetes. Methods: The research design for this study was a non-equivalent control group quasi-experimental study. Pregnant women with gestational diabetes were recruited from D women's hospital located in Gyeonggi Province from April to October, 2013. Participants in this study were 34 for the control group and 34 for the experimental group. The experimental group participated in the Coaching Program on Comprehensive Lifestyle Modification. The program consisted of education, small group coaching and telephone coaching over 4weeks. Statistical analysis was performed using the SPSS 21.0 program. Results: There were significant improvements in self-care behavior, and decreases in depression, fasting blood sugar and $HbA_1C$ in the experimental group compared to the control group. However, no significant differences were found between the two groups for knowledge of gestational diabetes mellitus. Conclusion: The Coaching Program on Comprehensive Lifestyle Modification used in this study was found to be effective in improving self-care behavior and reducing depression, fasting blood sugar and $HbA_1C$, and is recommended for use in clinical practice as an effective nursing intervention for pregnant women with gestational diabetes.

사업장의 당뇨 환자를 위한 모바일 중재프로그램 적용 효과 (Effects of Mobile Health Intervention for Employees with Diabetes in Workplace)

  • 서범준
    • 디지털융복합연구
    • /
    • 제18권10호
    • /
    • pp.371-379
    • /
    • 2020
  • 본 연구의 목적은 당뇨로 진단받은 임직원 대상으로 모바일을 통한 중재프로그램의 효과를 확인하기 위함이다. A직장의 임직원중 공복혈당 (Fasting Blood Glucose≥100mg/dL)에 해당하는 101명을 대상으로 부속의원에서 간호사가 혈액, 혈압 그리고 체질량지수를 측정하였다. 참여자에게 매일 혈당을 스스로 체크하도록 교육하고 12주간 혈당, 식이 그리고 운동에 대한 문자메시지를 제공하였다. 참여자의 일반적 특성은 기술통계로, 참여전과 참여 후는 paired t-test를 이용하여 혈당, 체질량지수 그리고 혈압을 확인하였다. 그 결과 공복시 혈당의 평균값이(129.38±1.95에서 123.63±1.82) 감소하였다(P<0.001). 체질량지수(26.20±0.29에서 25.81±0.28, P<0.000)와 이완기 혈압(124.60±1.03에서 122.56±1.05, P<0.032), 그리고 수축기 혈압(79.86±0.83에서 78.06±0.79, P<0.017)이 감소하였고 이는 통계적으로도 유의하였다. 당뇨를 가진 임직원에게 모바일을 활용하여 약물복용, 운동 그리고 식이에 대해 중재하는 프로그램을 개발하는데 기초자료로 활용되어지기를 기대한다.

혈당 강하 요구르트 개발에 관한 연구 (Studies on the Development of the Yogurt Decreasing Blood Glucose)

  • 조영훈;신현정;장치훈;남명수
    • 한국축산식품학회지
    • /
    • 제26권2호
    • /
    • pp.257-262
    • /
    • 2006
  • 혈당 강하 요구르트의 개발을 위해 Streptococcus salivarius subsp. thermophilus와 Lactobacillus acidophilus145, bifido-bacterium infantis 혼합균주에 사균인 FK-23 유산구균, 피니톨, 식이섬유, 백강낭콩 추출 분말, 에리스리톨, 바나바 추출물 등의 기능성 성분을 포함한 요구르트를 제조하여 정상인과 혈당치가 높은 당뇨환자를 대상으로 간이 임상시험을 실시하였다. 1. 정상인의 식후 혈당치는 일반 요구르트를 섭취했을 때보다 혈당 강하 요구르트 음용 시 더 낮게 측정되었으여 임상대상자 대부분에서 동일한 현상이 나타났다. 2. 혈당치가 높은 당뇨환자 10명을 대상으로 식후 혈당치변화 및 음용기간 중 혈당치 변화를 확인한 결과 혈당 강하요구르트를 음용하기 전보다 음용 후 혈당치가 식후 30분, 식후 60분, 식후 120분 각각 19 mg/dL, 30 mg/dL, 31 mg/dL 감소하였다. 또한, 혈당 증가 억제율도 임상대상자의 80%가 감소하는 효과를 나타냈다. 3. 30일간 혈당 강하 요구르트를 음용한 후 식후 혈당치의 변화를 확인한 결과 음용전보다 음용 후 120분 경과 때, 혈당치가 59 mg/dL 감소하였으며 음용기간이 증가할수록 지속적으로 감소하는 경향을 나타내었다.