• 한국지역사회생활과학회지
• /
• 제24권2호
• /
• pp.233-241
• /
• 2013

This study was conducted to evaluate the quality characteristics and the hypoglycemic effect of cookies containing Helianthus tuberosus powder (HTP). To examine the effect of adding HTP, cookies with various HTP contents (0%, 10%, 20%, 30%, 40%) were made and compared for their quality characteristics. The pH of cookie doughs decreased significantly (p<0.05) as the content of HTP increased. However, the density did not show significant difference among samples. The spread ratio and loss rate in cookies showed significant increase (p<0.05) as the content of HTP increased. However the leavening rate and the hardness of the cookies decreased significantly (p<0.05) when HTP content increased. Color measurement also showed significant difference among samples, although the cookie sample with 10% HTP powder showed the highest scores from consumer tests and liking score, the cookie samples with 30% HTP were selected to measure the hypoglycemic effect of Helianthus tuberosus compared to control cookies and bread. Ten healthy subjects in their twenties participated in measuring blood glucose levels after intake of bread, control cookie, or 30% HTP cookie. Blood glucose level was measured after fasting 12 hours, before eating, and 30, 60, 90, and 120 minutes after taking the samples. As a result, the blood glucose levels at 30min after meals showed significant (p<0.05) difference among treatments: the lowest when taken the cookies added 30% HTP. However there was no difference in the blood glucose levels at 60min, 90min, and 120min after the sampling.

• Nutrition Research and Practice
• /
• 제8권4호
• /
• pp.417-424
• /
• 2014

BACKGROUD/OBEJECTIVES: It is hypothesized that obese people with dyslipidemia is more likely to have increased oxidative stress and decreased antioxidant status, in comparison with the controls who were obese without dyslipidemia. Thus, the aims of the present study were to determine the dietary intakes, plasma adipokines, and antioxidative systems between obese with dyslipidemia and obese without dyslipidemia were investigated. SUBJECTS/METHODS: Female subjects who were between 20 and 55 years old, and whose BMI was 23 or greater were recruited. Subjects who met the criteria of $BMI{\geq}23$, total cholestero ${\geq}200mg/dL$, LDL cholesterol ${\geq}130mg/dL$, and $TG{\geq}110mg/dL$ were categorized Obese with dyslipidemia. Anthropometric measurements and blood biochemical tests were conducted. The diet survey was conducted by a trained dietitian using two days of 24 hour dietary recall. The lipid peroxidation, the plasma total antioxidant capacity (TAC), the activities of antioxidantive enzymes, and various antioxidantive vitamins levels were determined. RESULTS: Plasma adiponectin and leptin levels were also determined. There were no significant differences for age, Body Mass index (BMI), and body fat (%), waist-size between two groups. Obese with dyslipidemia had significantly high levels of total cholesterol, triglyceride, LDL-cholesterol, the ratio of total cholesterol/HDL-C, and the ratio of HDL-C/LDL-C, respectively. Blood alkaline phosphatase level was statistically different between the two groups (P < 0.05). No statistical significance in dietary intake between two groups was shown. In case of obese with dyslipidemia group, the levels of GSH-Px (P < 0.05) and catalase (P < 0.05) as well as adjusted blood retinol (P < 0.05) and tocopherol level (P < 0.05) were significantly low. However, the plasma concentration of leptin was significantly high (P < 0.05). CONCLUSIONS: Obesity with dyslipidemia was shown to have high arthtrogenic index, depleted antioxidant status, and higher blood leptin levels which suggest higher risks of oxidative stress and cardiovascular diseases.

• 한국식품영양과학회지
• /
• 제19권1호
• /
• pp.53-60
• /
• 1990

농촌 주부의 식생활상태는 건강과 밀접한 관계를 가지므로 식생활환경과 식사내용 및 혈액 성상에 대한 내용을 분석 비교하였다. 대상자의 학력은 낮으며 가족수는 전국평균보다 많으며 약한 저체중상태가 60%나 되었다. 가정기기의 사용률은 중간 정도이나 농기계 보유율은 1.36대에 불과 하였으며 위생생활은 이루어진다고 볼 수 있으나 문화생활수준은 매우 낮았다. 혈압은 정상보다 낮으며 농부증은 4.72점으로서 요관찰대상점수였다. 식품군별 섭취량은 전반적으로 낮았으며 곡류와 채소가 주류이고 동물성식품은 빈약하였다. 영양소는 비타민C 및 아니아신을 제외하고 모두 권장량에 미치지 못하였으며 칼슘은 66.3%, 철분은 56.6%로서 특히 낮았다. 혈액성상은 혈청단백질은 정상으로 지질, 칼슘, 마그네슘 등은 정상범위는 벗어나지 않으나 낮은 수준이었다. 혈청철분과 헤모글로빈, 헤마토크릿은 낮은 수치가 많아 빈혈빈도가 높음을 보였으며 혈청 ferritin은 특히 낮았다. 각 요인의 상관관계를 보면, 곡류를 혈청마그네슘과 높은 상관을 보였고 혈청콜레스테롤은 곡류, 유지류, 채소류, 육류의 섭취와 상관을 보이고 체중과 신체충실지수와 밀접한 상관을 보였다. 빈혈과 관련하여 볼 때 헤모글로빈과 헤마토크릿 수치는 과일류, 생선류의 섭추와는 음의 상관을, 신체충실지수와는 양의 상관을 보였다.

• 한국산학기술학회논문지
• /
• 제15권3호
• /
• pp.1641-1649
• /
• 2014

본 연구는 대장 용종 발생의 위험인자를 파악하기 위해 종합검진 수검자 중 대장내시경 검사와 복부초음파검사를 동시에 시행 받은 508명을 대상으로 나이, 성별, 흡연, 음주, 운동의 일반적인 특성과 신장, 체중, 혈압, 허리둘레, 체질량 지수 등의 신체 계측을 하였으며, 동시에 채혈을 통한 공복 시 혈당과 여러 가지 혈액검사를 분석하였다. 그 결과 AST, ALT, 총콜레스테롤, 지방간, 비만도 및 흡연여부가 유의하게 높은 것으로 나타났으며 대장용종이 있는 대상자가 지방간과의 관련성이 3.4배로가 가장 높았고, 다음으로 총콜레스테롤 2.3배, 흡연자가 비흡연자에 비해 2.3배나 위험성이 높게 나타났다.

• 한국건설순환자원학회논문집
• /
• 제7권1호
• /
• pp.69-75
• /
• 2012

본 연구는 모르타르와 콘크리트에 첨가제로서, 돈혈을 혼합하였을 때 물성에 미치는 영향을 알아보기 위해 실험을 실시하였다. 모르타르 실험에는 단위질량, 플로우, 압축강도 실험을 실시하였고, 콘크리트 실험에는 공기량, 슬럼프, 블리딩, 응결시간, 압축강도, 동결융해저항성 실험을 실시하였다. 실험 결과로서, 돈혈을 모르타르와 콘크리트에 첨가하면 공기연행효과를 가지는 것으로 나타났다. 모르타르 실험에서는 플로우 값은 증가하며, 단위중량은 감소하고, 압축강도는 공기연행에 의해 감소하였다. 콘크리트 실험에서는 돈혈을 첨가하였을 때 공기연행효과로 공기량은 증가하나, 시간이 경과함에 따라 공기량이 감소하는 경향이 있으며, 응결시간이 지연되고, 블리딩량은 감소하는 경향을 보이는 것으로 나타났다. 콘크리트의 압축강도는 공기연행작용으로 인하여 강도가 감소하며, 동결융해 저항성은 향상되는 효과가 있는 것으로 나타났다.

• Childhood Kidney Diseases
• /
• 제22권2호
• /
• pp.42-46
• /
• 2018

Purpose: We investigated whether the white blood cell (WBC) count to hemoglobin (Hgb) level ratio is correlated with the presence of cortical defects on dimercaptosuccinic acid (DMSA) renal scan in children with febrile urinary tract infection (UTI). Methods: We examined 95 children who were consecutively admitted to our hospital with their first episode of febrile UTI. Blood tests (C-reactive protein [CRP], WBC, Hgb] were performed. All enrolled children underwent DMSA scanning during admission. Data were compared between children with positive and negative DMSA results. The correlations between WBC to Hgb ratio and the presence of cortical defects on DMSA scan, and between WBC to Hgb ratio and CRP level were analyzed using the Pearson chi-squared test. Multiple logistic regression analysis was used to evaluate whether WBC to Hgb ratio could predict the cortical defects on DMSA scan in children with febrile UTI. Results: The WBC to Hgb ratio was significantly higher in children with positive DMSA results than in those with negative DMSA results; positively correlated with the presence of cortical defects on DMSA scan and CRP; and was a significant factor for predicting the presence of cortical defects on DMSA scan. Conclusion: The WBC to Hgb ratio may predict the presence of cortical defects on acute DMSA scans in children with febrile UTI.

• 한국식품영양학회지
• /
• 제26권3호
• /
• pp.366-374
• /
• 2013

Anti-diabetic activities of cultured mycelia from Ganoderma applanatum are being evaluated in this study. The OGTT and 4-weeks of repeated oral efficacy tests are conducted in mice at the doses of 0 (vehicle treatment), 25, 75 and 225 mg/kg/day, respectively. In human study, the test article was administered orally every day for 8-week at a dose of 1,500 mg/kg, tid and placebo group. The blood glucose levels (BGL) at 0.5 hour after treatment are significant decreased in all treatment groups of OGTT test. In the 4-week test, BGL of 75 and 225 mg/kg/day group is continuously decreased during all treatment periods and the BGL of 25 mg/kg/day group show decreasing trends at the final week, the pancreas weight of all treatment groups are being increased, and the Langerhans-islet numbers were increased at all treatment groups with a dose-response manner. There are no test article-related abnormal signs and the fasted blood glucose (FBG), postprandial blood glucose (PPG) and HbA1c are decreased significantly after 8-week treatments. These results that the cultured mycelia from Ganoderma applanatum could decrease BGL by protecting the degeneration of Langerhans islets.

• 대한지역사회영양학회지
• /
• 제2권4호
• /
• pp.568-577
• /
• 1997

To assess the nutritional and health status of the elderly, anthropometric measurements and blood test for analyzing biochemical indices were carried out from August to September in 1996. Data on the incidence of a specific disease and clinical symptoms were also collected by interviews with a questionnaire. Among the total of 169 free-living elderly interviewed(91 men, 78 women), 86 elderly(57 men, 29 women) participated in the anthropometric measurements, and 73 elderly(52 men, 21 women) in blood tests. Average heights and weights were much lower than the standards established in the Korean Recommended Dietary Allowances. While average triceps skinfold thickness of men and women were above the 50 percentile of the reference data, mid-arm muscle circumferences were lower than the 50 percentile. Prevalences of anemia, assessed by hemoglobin using WHO definition, were 38.5% for men and 33.3% for women. Blood levels of total protein and albumin were above the normal limit for all participants. Mean blood cholesterol levels of men and women were 163.9mg/dl and 185.8mg/dl, and triglyceride levels were 138.2mg/dl and 161.9mg/dl, respectively. Women older than 75 years generally had high levels of BMI, total cholesterol and triglyceride. Health status assessed by clinical symptoms generally showed no significant difference by age, and their smoking, and drinking habits. Males and the elderly who exercised regularly had better health status. It was suggested that exercise was a good way to improve health status. (Korean J Community Nutrition 2(4) : 568-577, 1997)

• 대한약침학회지
• /
• 제20권1호
• /
• pp.45-51
• /
• 2017

Objectives: This study aimed to evaluate the hypoglycemic effects of an ethanol extract of Cassia abbreviata (ECA) bark and the possible mechanisms of its action in diabetic albino rats. Methods: ECA was prepared by soaking the powdered plant material in 70% ethanol. It was filtered and made solvent-free by evaporation on a rotary evaporator. Type 2 diabetes was induced in albino rats by injecting 35 mg/kg body weight (bw) of streptozotocin after having fed the rats a high-fat diet for 2 weeks. Diabetic rats were divided into ECA-150, ECA-300 and Metformin (MET)-180 groups, where the numbers are the doses in mg.kg.bw administered to the groups. Normal (NC) and diabetic (DC) controls were given distilled water. The animals had their fasting blood glucose levels and body weights determined every 7 days for 21 days. Oral glucose tolerance tests (OGTTs) were carried out in all animals at the beginning and the end of the experiment. Liver and kidney samples were harvested for glucose 6 phosphatase (G6Pase) and hexokinase activity analyses. Small intestines and diaphragms from normal rats were used for ${\alpha}-glucosidase$ and glucose uptake studies against the extract. Results: Two doses, 150 and 300 mg/kg bw, significantly reduced the fasting blood glucose levels in diabetic rats and helped them maintain normal body weights. The glucose level in DC rats significantly increased while their body weights decreased. The 150 mg/kg bw dose significantly increased hexokinase and decreased G6Pase activities in the liver and the kidneys. ECA inhibited ${\alpha}-glucosidase$ activity and promoted glucose uptake in the rats' hemi-diaphragms. Conclusion: This study revealed that ECA normalized blood glucose levels and body weights in type 2 diabetic rats. The normalization of the glucose levels may possibly be due to inhibition of ${\alpha}-glucosidase$, decreased G6Pase activity, increased hexokinase activity and improved glucose uptake by muscle tissues.

• 한방안이비인후피부과학회지
• /
• 제33권4호
• /
• pp.44-54
• /
• 2020

Objectives : In the present study, we investigated whether or not an herb mixture including Lycii fructus(HML) has attenuation effects on light stress in rats. Methods : Light stress was induced by exposure to 300 lx of constant lifht for 24 h and 1mg/kg of caffeine was injected into the rat. Rats were orally treated with distilled water of HML for 21 days at 100mg/kg/d. The changes of mortality rate, clinical signs, body, blood chemistry, melatonin and IL-2 expression were analyzed after experiment. Results : Normal weight changes were observed in all treatment groups. In addition, no changes were observed in dead animals and general symptoms. At the time of autopsy, the appearance of all groups and gross examination of major organs were observed, and no gross findings were observed. Blood biochemical tests showed that total cholesterol and HDL cholesterol levels were statistically significantly decreased in the group treated with HML compared to the stress-induced group. Melatonin was measured in the blood, but there was no significant difference in the group treated with HML compared to the group with stress-induced group, but it tended to increase. IL-2 was measured in the blood, no significant change was observed in the group treated with HML compared to the stress-induced group. Conclusions : According to the above results, HML maybe help with hematological changes expressed by caffeine and light-induced stress.