• The Journal of Korean Physical Therapy
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• 제30권2호
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• pp.41-46
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• 2018

Purpose: This study examined the effects of knee extension exercise using blood flow restriction on the changes in the thickness and static balance ability of the tendon of the rectus femoris muscle and achilles tendon. Methods: A total of 30 subjects was were divided into two groups of 15 subjects each. The changes in the thickness and balance of their tendons were measured by ultrasonography and balance equipment. The measurements were taken three times: before the experiment, 4 weeks after, and 8 weeks after. The results were analyzed by repeated measure ANOVA, one-way ANOVA was conducted in cases where there were time-to-group interactions in the intra-individual effects test. Results: Significant differences in the thickness of the tendon of the rectus femoris muscle and Achilles tendon were found between the groups, over time, and in the time-to-group interactions (p<0.05). The changes in balance in both feet when the supporting positions between eye-open and eye-closed states were significantly different in the time-to-group interactions (p<0.05), but were not different between the groups (p>0.05). Conclusion: Knee extension exercise using blood flow restriction leads to significant differences in the increase in tendon thickness and changes in balance, indicating that the results of this study can be utilized as basic data for future studies and for rehabilitation treatment at clinics.

• 한국산학기술학회논문지
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• 제19권3호
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• pp.489-498
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• 2018

이 연구의 목적은 만성질환의 발병 위험성이 높은 직장 중년 비만여성을 대상으로, 낮은 강도의 혈류를 제한한 4주간의 걷기트레이닝이 인슐린저항성과 아디포카인, Gut 호르몬에 어떠한 영향을 미치는 지를 구명하고자 한다. 연구의 대상자는 BMI $25kg/m^2$와 체지방률 30% 이상의 직장 중년 비만여성 11명으로 하였으며 혈류의 제한은 특수제작 된 공압식 가압벨트를 사용해 사지의 혈류를 제한하였다. 혈류를 제한한 걷기트레이닝은 대퇴부위 양쪽에 공압방식의 탄성벨트를 착용하고 압력을 조절하여 4주간, 주당 3일, 1일 2회 트레드밀을 이용하여 실시하였고 걷기프로그램은 4km/h의 속도와, 5%의 경사도로 2분 걷기와 1분 휴식으로 구성하여 총 5세트 반복하였다. 이 연구의 결과에서 4주간의 혈류를 제한한 걷기트레이닝 후, 인슐린의 농도는 유의하게 증가하였으나(p<.05) 글루코스의 농도는 증가하는 경향을 보였으나 유의한 차이를 보이지 않았으며 HOMA-IR은 유의하게 감소되었다(p<.05). 아디포넥틴과 비스파틴의 농도는 트레이닝 후, 증가하는 경향을 보였으나 통계적 유의차는 나타나지 않았다. 또한 그렐린과 GLP-1의 농도는 모두 4주간의 혈류를 제한한 걷기트레이닝 후, 유의하게 감소되었다(p<.05). 이상의 결과에서, 4주간의 혈류를 제한한 걷기트레이닝은 직장 중년 비만여성들의 인슐린 저항성과 아디포카인, Gut 호르몬 변화에 효과가 있는 것으로 생각되며 이러한 결과는 낮은강도와 짧은 시간의 혈류를 제한한 트레이닝이 비만의 예방과 치료적 차원에서 긍정적 효과가 있는 것으로 사료된다.

• 한국엔터테인먼트산업학회논문지
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• 제14권4호
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• pp.333-340
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• 2020

본 연구는 하지혈류제한벨트를 한 그룹과 하지 않은 그룹의 균형과 순발력의 변화를 알아보기 위해 광주 지역에 소재한 K대학교 학생 40명을 선정하여 실험군 20명과 대조군 20명을 무작위 배치하여 2019년 9월 16일부터 10월 11일까지 4주간 스쿼트 운동을 실시하였다. 스쿼트 운동 시 혈류제한은 BFR band를 착용하였고 편안하게 선 상태에서 120 mmHg 압력을 넣어 하지혈류제한을 하였다. 실험 결과 앞·중간·뒷부위 발바닥 압력의 시간에 따른 변화에서 두 그룹 모두 통계학적으로 유의한 차이가 나타나지 않았고(p>.05), 실험군과 대조군 간 상호작용 차이도 없었다(p>.05). Height, Maximum Concentric Power, Take Off Speed에서 시간에 따른 유의한 차이를 확인할 수 있었다(p<.05). 이와 같은 결과로 보아 낮은 강도 운동을 통해서도 하지혈류제한을 통해 큰 효과를 얻을 수 있을 것으로 사료된다. 본 논문은 혈류제한운동이 순발력과 균형에 미치는 영향을 알아보고자 하였으며 향후 하지혈류제한 운동을 통해 낮은 강도의 운동으로도 큰 운동 효과를 얻을 수 있는 것의 기초자료로 활용될 수 있을 것이다.

• PNF and Movement
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• 제10권1호
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• pp.61-70
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• 2012

Purpose : The purpose of this study was to investigate thigh muscle-bone CSA and leg strength during low-intensity exercise program with leg blood flow restriction by external compression to reduce muscle outflow. Methods : Eighteen health students gave informed written consent to participate in this investigation. An occlusion cuff was attached to the proximal end of the leg so that blood flow was reduced during the training. The training was conducted one times a day, three times a week, for 8 weeks using one sets of 30 minutes. The training program performed to squat with standing, lunge with standing and heel raise with one leg standing. Measurements of thigh muscle-bone CSA(cross-sectional area) and leg strength were evaluated pre and post-training. Statistical evaluation of these data was accomplished utilizing a paired t-test by SPSS 12.0 program for windows. Significance level was set at p <.05. Results : All data are reported as means and standard deviations(SD) for all variables. The result of the study is followed; After the training, muscle-bone CSA, gluteus maximus m, quadriceps m, hamstring m of both legs were significantly improved but not calf muscle(p<.05). There was no significant difference of change quantity between muscle-bone CSA and leg strength in Lt. and Rt. side. But the variation in leg muscle strength of Rt. leg(dominant) was much more increased than Lt. leg(non-dominant) after 8 weeks training. Conclusion : Low-intensity training with leg blood flow restriction offers a potentially useful method for improving leg muscle strength.

• The Journal of Korean Physical Therapy
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• 제29권2호
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• pp.80-84
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• 2017

Purpose: This study was conducted to examine the effects of different sizes of blood flow restriction areas on the thickness of the external oblique and biceps brachii. Methods: The study subjects were 52 adults who were divided into four groups that performed plank exercises over a six-week period after blood flow restriction. Changes in the thickness of the external oblique and biceps brachii were measured using ultrasonography before the experiment, then three and six weeks after the experiment. The changes in each variable over time were evaluated by repeated-measures analysis of variance (ANOVA). Results: The external oblique and biceps brachii showed significant differences in muscle thickness with regard to time and the interaction between time and each group (p<0.01), but no significant differences with regards to changes between groups (p>0.05). Conclusion: A larger blood flow restriction area resulted in a statistically significant increase in muscle thickness. The results of this study may be used as the basis for future studies and for rehabilitation in clinical practice.

• The Journal of Korean Physical Therapy
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• 제29권2호
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• pp.69-73
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• 2017

Purpose: This study was conducted to investigate the effects of blood flow restriction and different support surfaces for bridge exercises on the thickness of the transverse abdominis and multifidus, which are trunk-stabilizing muscles. Methods: The study's subjects were 45 adults who were divided into three groups that performed bridge exercises over a six-week period on their respective support surfaces after blood flow restriction. Changes in the thickness of the subjects' transverse abdominis and multifidus muscles were measured using ultrasonography before the experiment, then three and six weeks after the experiment. The changes in each variable over time were analyzed using a repeated-measures analysis of variance (ANOVA). Results: The transverse abdominis showed significant differences in muscle thickness with regard to time and the interaction between time and each group (p<0.05), but no significant differences with regard to changes among groups (p>0.05). The multifidus showed significant differences in muscle thickness with regard to time, the interaction between time and each group, and changes between groups (p<0.05). Conclusion: Blood flow restriction and different support surfaces for bridge exercises led to significant differences in the thickness of the transverse abdominis and multifidus. This study's results may be used as the basis for future studies and for rehabilitation in clinical practice.

• 운동영양학회지
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• 제24권2호
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• pp.30-37
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• 2020

[Purpose] The present study investigated the effect of endurance exercise with blood flow restriction (BFR) performed at either 25% maximal oxygen uptake (${\dot{V}}O_2$ max) or 40% ${\dot{V}}O_2$ max) on muscle oxygenation, energy metabolism, and endocrine responses. [Methods] Ten males were recruited in the present study. The subjects performed three trials: (1) endurance exercise at 40% ${\dot{V}}O_2$ max without BFR (NBFR40), (2) endurance exercise at 25% ${\dot{V}}O_2$ max with BFR (BFR25), and (3) endurance exercise at 40% ${\dot{V}}O_2$ max with BFR (BFR40). The exercises were performed for 15 min during which the pedaling frequency was set at 70 rpm. In BFR25 and BFR40, 2 min of pressure phase (equivalent to 160 mmHg) followed by 1 min of release phase were repeated five times (5 × 3 min) throughout 15 minutes of exercise. During exercise, muscle oxygenation and concentration of respiratory gases were measured. The blood samples were collected before exercise, immediately after 15 min of exercise, and at 15, 30, and 60 minutes after completion of exercise. [Results] Deoxygenated hemoglobin (deoxy-Hb) level during exercise was significantly higher with BFR25 and BFR40 than that with NBFR40. BFR40 showed significantly higher total-hemoglobin (total-Hb) than NBFR40 during 2 min of pressure phase. Moreover, exercise-induced lactate elevation and pH reduction were significantly augmented in BFR40, with concomitant increase in serum cortisol concentration after exercise. Carbohydrate (CHO) oxidation was significantly higher with BFR40 than that with NBFR40 and BFR25, whereas fat oxidation was lower with BFR40. [Conclusion] Deoxy-Hb and total Hb levels were significantly increased during 15 min of pedaling exercise in BFR25 and BFR40, indicating augmented local hypoxia and blood volume (blood perfusion) in the muscle. Moreover, low-and moderate-intensity exercise with BFR facilitated CHO oxidation.

• 한국산학기술학회논문지
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• 제18권10호
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• pp.480-489
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• 2017

혈류를 제한한 운동은 가압벨트를 사용해 사지의 윗부분을 적당한 정도로 압박한 상태에서 트레이닝을 실시하며 인체의 다양한 생리적 기능에 영향을 미치는 것으로 알려져 있다. 이 연구의 목적은 만성질환의 발병 위험성이 높은 비만여성을 대상으로, 낮은 강도의 혈류를 제한한 걷기운동이 신체조성 및 성장호르몬, 근손상지표에 어떠한 영향을 미치는 지를 구명하고자 한다. 연구대상자는 BMI $25kg/m^2$와 체지방률 30% 이상의 직장 비만여성 11명으로 하였으며 혈류제한은 공압방식의 탄성벨트를 양쪽의 대퇴부위에 착용하고 압력을 조절하였다. 걷기프로그램은 트레드밀을 이용하여 실시하였으며(4주, 주 3일, 1일 2회), 2분 걷기와 1분 휴식으로 구성하여 총 5세트 반복하였고(4km/h, 5%) 대응표본 t-test를 실시하였다. 4주간의 혈류를 제한한 걷기운동 후, 체중과 신체질량지수, 체지방량이 유의하게 감소하였으며(p<.05), 우측의 대퇴둘레 또한 유의하게 감소되었다(p<.05). 혈중 염증지표의 농도변화에서 IL-6는 4주간의 혈류를 제한한 걷기운동 후, 유의하게 증가되었으며(p<.05), 통계적 유의수준에는 도달하지 못하였지만 TNF-${\alpha}$는 증가하는 경향을, CRP는 감소하는 경향을 보였다. 등속성 근기능의 변화에서 $60^{\circ}/sec$의 좌 우측 신전력(좌, p<.001; 우, p<.05)과 좌측의 굴곡력(p<.001)이 유의하게 증가되었으며 $180^{\circ}/sec$의 좌측 신전력에서 유의하게 증가되었다(p<.001). 이상의 결과로부터 4주간의 혈류를 제한한 걷기운동이 비만 중년여성의 체중 및 체지방량 감소와 근 기능 향상, 혈중 염증지표 농도의 변화에 긍정적인 효과가 있는 것으로 사료되며, 이는 짧은 운동시간에도 불구하고 장시간의 운동 효과를 얻을 수 있음을 검증한 것과 동시에 각종 만성성인질환 및 대사성 질환의 원인인 비만을 예방하고 치료하는데 효과가 있는 것으로 생각된다.

• Advances in nano research
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• 제14권3호
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• pp.247-259
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• 2023

Muscle strength and hypertrophy are equivalent when low-intensity resistance exercise is paired with blood flow restriction. This paper deals with the impact of physical exercise in the form of body activities on drug delivery using nanodevices. The body's actions impact the blood flow since the nano drug delivery devices are released into the bloodstream, and physical exercise and all the activities that change the blood flow influence the stability of these nanodevices. The nanodevice for the drug delivery purpose is modeled via nonuniform tube structures based on the high-order beam theory along with the nonlocal strain gradient theory. The nanodevice is made by a central nanomotor as well as two nanoblade in the form of truncated conical nanotubes carrying the nanomedicine. The mathematical simulation of rotating nanodevices is numerically solved, and the effect of various parameters on the stability of nanodevices has been studied in detail after the validation study.

• PNF and Movement
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• 제20권2호
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• pp.235-241
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• 2022

Purpose: The purpose of this study was to identify the effects of low intensity blood flow restriction training (LBFR) on the central nervous system of healthy adults. Methods: Ten healthy right-handed adults (eight males and two females, mean age of 28.6 ± 2.87 years) were selected as study subjects. Functional magnetic resonance imaging (fMRI) was conducted to measure brain activation (BA) following LBFR and non-LBFR. The primary motor area, premotor area, and supplementary motor area, which are closely related to exercise, were set as the regions of interest. Results: The BA recorded during the LBFR condition was 931.7 ± 302.44 voxel, and the BA recorded during the non-LBFR condition was 1,510.9 ± 353.47 voxel. Conclusion: BA was lower during LBFR than during non-LBFR.