• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.220.2-220.2
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• 2003

Many interference in blood should be considered for non-invasive blood glucose level monitoring by near-infrared spectroscopy because blood glucose concentration is about 0.1% (w/v) in normal state. In this study, we investigated the influence of other blood components on blood glucose level monitoring by near-infrared spectroscopy. It carried out by newly developed portable type-NIR system (1100∼2200 nm). Spectrum features of NIR diffuse spectral data were investigated for some blood compnents powder such as hemoglobin, blood serum albumin, urea, uric acid, ascorbate, glucose, cholesterol and as adding glucose powder into other blood components powder mixture. (omitted)

• 약학회지
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• 제48권3호
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• pp.171-176
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• 2004

This study was described for measuring clinically relevant levels of glucose in undiluted plasma and whole blood by near-infrared (NIR) spectroscopy. Result from an initial measurement of major blood components powder was over-lapped the absorption bands of glucose at 1500-1600 nm. However, the NIR data of blood components were clearly separated by principle component analysis (PCA) space. By the use of partial least squares (PLS) regression, glucose concentrations in undiluted plasma and whole blood could be determined with standard errors of prediction (SEP) of 15 mg/dl and 76 mg/dl, respectively. Although these blood components possessed strong absorption bands that overlapped with the absorption bands of glucose, successful calibration models could be carried out.

• Journal of Animal Science and Technology
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• 제46권3호
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• pp.325-334
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• 2004

본 연구는 인도산 허브를 이용하여 제조한 Animunin Powder${\circledR}$를 자돈 및 육성돈에 첨가 급여시 그 성장과 혈액내의 면역반응을 알아보고자 실시하였다. 시험 1은 3원 교잡종(Landrace ${\times}$ Yorkshire ${\times}$ Duroc) 자돈 96두를 공시하였으며 시험개시시의 체중은 평균 20.72 ${\pm}$ 2.63kg이었고 1) Con(Control),2) AB(Control + 0.1% Antibiotics), 3) AM(Control + 0.1% Animunin Powder${\circledR}$)로 4개 처리를 하여 처리당 6반복 반복당 4두씩 임의 배치하여 4주간 실시하였다. 전체 사양시험기간동안 ABM 처리구가 대조구에 비해 유의적으로 ADG와 ADFI가 높았다(P < 0.05). IgG에서는 AM 처리구와 ABM 처리구가 AB 처리구에 비해 유의적으로 높았다(P < 0.05). Albumin에서는 ABM 처리구가 CON과 AM처리구에 비해 유의적으로 높았으며(P < 0.05) lymphocyte에서는 AB 처리구와 ABM 처리구가 CON과 AM 처리구에 비해 유의적으로 높은 결과를 나타냈다(P < 0.05). 건물의 소화율에서는 ABM 처리구가 AB와 AM 처리구에 비해 유의하게 높은 결과를 보였다(P < 0.05). 시험 2는 3원 교잡종 (Landrace ${\times}$ Yorkshire ${\times}$ Duroc) 육성돈 75두를 공시하였으며 시험개시시의 체중은 평균 40.22 ${\pm}$ 2.82kg이었고 1) CON(Control), 2) AM1(Control + 0.1% Animunin Powder${\circledR}$), 3) AM2(Control + 0.2% Animunin Powder${\circledR}$)으로 3개 처리를 하여 처리당 5반복 반복당 5두씩 임의 배치하여 29일간 실시하였다. 전체 사양시험기간 동안 AM1과 AM2 처리구가 CON 처리구에 비해 ADG가 유의하게 높았고(P < 0.05) ADFI에서는 AM1 처리구가 CON 처리구에 비해 유의하게 높은 값을 보였다(P < 0.05). Total protein에서는 AM2 처리구가 CON과 AM1 처리구 보다 유의하게 높았으며(P < 0.05) lymphocyte에서는 AM1, AM2, CON순으로 유의적인 차를 나타내었다(P < 0.05). 결론적으로 사료 내 Animunin Powder${\circledR}$의 첨가는 성장과 혈액 내 면역반응에 효과적인 것으로 사료된다.

• 대한가정학회지
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• 제29권2호
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• pp.55-64
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• 1991

This study was designed to elucidate the effects of mugwort powder supplemented to high fat diets on blood components levels in rats. The levels of mugwort content in the experimental diets were divided into 12, 21, 28% and the fat levels in high fat diet was 30% of total caloie intake. Forty-nine male Sprague-Dawley rats weighing 72.5$\pm$0.3g were divided into group I(add mugwort during 8 weeks), group II(add during 4 weeks) andcontrol group. The results of this study were summarized as follows : 1. There were no difference in body weight gain and FER throughout eight weeks of experiment. The organ weights were somewhat higher in control group, but not significant. 2. The mugwort groups(I, II) were significantly higher than control group in RBC. This result showed that the mugwort affect the content of RBC. Author would like to conclude this result that the RBC content of experim-ental animal was affected by the iron in the mugwort. There were no difference among experimental groups in Hb, Hct. 3. It was noteworty that the concentration of serum glucose and triglyceride in the mugwort groups(I, II) was significantly lower than the control group. This result concluded that concentration of serum glucose and triglyceride which had become high by high fat diet were affected by the calcium or dietary fiber in the mugwort. There were no difference among experimental groups in albumin, total cho-lesterol, HDL-cholesterol.

• 한국가금학회지
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• 제31권4호
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• pp.237-244
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• 2004

본 연구는 산란계에 Animunin Powder$^{(R)}$를 첨가 급여시 계란 품질, 혈액 성상 및 영양소 소화율에 미치는 영향을 알아보고자 실시하였다. 이를 위해 22주령 Hy-line Brown 270수를 공시하였고 사양시험은 10일간의 적응기간 후, 5주간 실시하였다. 시험처리구는 Animunin Powder$^{?}$의 첨가수준에 따라 1) Control(CON), 2) Control + $0.1\%$ Animunin Powder$^{(R)}$ (AM1), 3) Control + $0.2\%$ Animunin Powder$^{(R)}$ (AM2)로 3개 처리를 하여 처리당 15반복 반복당 6수씩 임의배치하였다. 산란률은 4주 동안의 기간에서 AM1 처리구가 대조구보다 통계적으로 유의하게 높은 산란률을 보였으며(P<0.05), 8주 동안의 기간에서도 AM1 처리구가 대조구보다 유의적으로 높은 산란률을 보였다(P<0.05). 난중에 있어서는 시험 기간동안 유의적인 차이를 발견할 수 없었다. 난황색은 8주에서 AM2 처리구가 대조구 및 AM1 처리구에 비해 유의하게 높았다(P<0.05). Haugh unit은 4주에서 AM 처리구가 대조구에 비해 유의하게 높은 수치를 보였다(P<0.05). 난각 강도는 처리구간 유의적인 차이를 발견하지 못하였으나, 8주에서 AM2 처리구가 대조구 및 AM1 처리구에 비해 높은 경향을 나타내었다. 난각 두께는 전 기간에 걸쳐 유의적인 차이를 보이지 않았다. 혈청내 콜레스테롤에서는 Animunin Powder$^{(R)}$ 첨가한 시험구에서 콜레스테롤 함량이 유의적으로 낮았다(P<0.05). RBC 및 WBC에서는 허브의 첨가 수준에 따라서 혈액내 RBC및 WBC의 함량이 증가하는 경향을 보였으나 유의적인 차이는 없었다. Lymphocyte는 개시시와 종료시의 변화에서 AM1 처리구가 대조구와 AM2 처리구에 비해 유의적으로 높았다(P<0.05). 4주 및 8주에서 AM1 처리구가 건물의 소화율에서 대조구 및 AM1 처리구에 비해 높은 결과를 나타내었지만 통계적으로 유의적인 차이를 발견하지 못하였다. 결론적으로 산란계에 Animunin Powder$^{(R)}$를 급여 시 생산성 향상에 도움을 주리라 사료된다.

• 한국식품영양학회지
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• 제29권3호
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• pp.411-419
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• 2016

In this study, we determined the effect of the mulberry leaf powder on blood lipid metabolism and liver function improvement of mice fed a high fat diet. The mulberry leaf showed a moisture content of $10.74{\pm}0.56%$, ash $9.67{\pm}0.56%$, crude protein $25.24{\pm}1.02%$, and crude fat $2.66{\pm}0.08%$. In the group with high fat diet supplemented with mulberry leaf powder, serum low-density lipoprotein (LDL-cholesterol) and total cholesterol levels were significantly lower (p<0.05); also, serum phospholipid and aspartate amino transferase (AST) levels were significantly lower (p<0.05). Serum insulin and leptin levels were high in mice fed a high fat diet; however, addition of mulberry leaf powder 10% in the diet had no significant effect on blood insulin and leptin control. The results of the study suggested that various plant sterols in mulberry leaf improve lipid metabolism and liver function in ICR-mice.

• 한국식품영양학회지
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• 제30권1호
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• pp.148-155
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• 2017

This study aimed to investigate the effect of acorn powder and starch on the blood parameters of mice fed a high-fat diet. The moisture, crude ash, crude protein, and crude fat contents of acorns were $37.99{\pm}0.37%$, $1.61{\pm}0.06%$, $4.36{\pm}0.18%$ and $3.22{\pm}0.15%$, respectively. Acorn powder and starch contains antioxidant minerals such as selenium and zinc. The iron content was significantly higher in acorn powder than in acorn starch (p<0.05). The total cholesterol concentration was $148.50{\pm}29.72mg/dL$ in the high-fat starch diet (HFS) group, while in the high-fat diet (HF) group it was $201.50{\pm}39.15mg/dL$ (p<0.05). Serum LDL-cholesterol concentrations were significantly lower in the HFS group ($50.50{\pm}10.79mg/dL$) than in the HF group ($62.00{\pm}20.85mg/dL$; p<0.05). The serum $IL-1{\beta}$ levels in mice were not significantly different between the groups. IL-10 levels were higher in the HFP group than other groups. There is a need for strong recognition that acorns are good ingredients worldwide. It is required to develop various products using acorn powder and starch powder. There is also a need for a strategy to globalize food using acorns.

• International Journal of Industrial Entomology and Biomaterials
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• 제29권2호
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• pp.162-168
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• 2014

1-Deoxynojirimycin(1-DNJ or DNJ), a component in silkworm powder, prevents glucose from being absorbed into the bloodstream from the small intestine by inhibiting ${\alpha}$-glucosidase activity. This study compared the functional components of 1-DNJ from various silkworm species using a gene database with those of 1-DNJ produced by silkworms bred through cross-combinations. We utilized comparisons of geographical origins and species of silkworms using a gene database and discovered that 1-DNJ activity was ranked in the following order by species, Japanese (SK-1) > Chinese (C48) > European (Rock191). 1-DNJ constituted varying percentages of silkworm organs in the following order, blood > epithelial tissue > body fat > silk glands. With regard to sex, 1-DNJ, levels were higher in males than females. However, 1-DNJ levels with respect to various genetic traits (blood color, silk color, and egg color) were consistent. In order to study 1-DNJ changes that occurred during cross breeding of the silkworm gene, we bred cross-combinations utilizing SK-1 and C48 silkworms. In conclusion, in order to provide information about the constituents of functional materials contained in silkworm powder, it is imperative that silkworm cross breeding occurs so that the database of functional materials extracted from silkworms will expand.

• 한국식품영양학회지
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• 제30권6호
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• pp.1157-1163
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• 2017

This study, analyzed the general and minerals composition of kamut and investigated its effect on blood components in mice fed a high fat diet. The content of each general component of kamut was as follows: $11.02{\pm}0.75%$ water, $13.16{\pm}1.28%$ crude protein, $1.85{\pm}0.19%$ crude fat, and $1.97{\pm}0.13%$ ash. The leptin level was the highest in the HF group($30.00{\pm}0.00ng/mL$) when compared to the control group. There was a significant decrease of $23.65{\pm}5.54ng/mL$ in the HFK group when compared to the HF group (p<0.05). The blood LDL-cholesterol concentration was the lowest in the control group at $10.00{\pm}2.00mg/dL$. The level was highest in the HF group at $28.00{\pm}0.00mg/dL$ when compared with the other groups (p<0.05). The aspartate transaminase (AST) level was significantly higher in the HFK group ($179.33{\pm}173.88U/L$) than in the control ($61.00{\pm}12.73U/L$) and HF groups ($132.00{\pm}0.00U/L$). According to the results of this study, the consumption of kamut lowers the blood LDL-cholesterol level more than the consumption of wheat flour. Additionally, kamut contains antioxidant substances such as selenium and zinc, which are thought to contribute to vascular health and thus aid in maintaining good health. Therefore, it is necessary to develop a variety of health foods using kamut; it should be used as a functional food for the maintenance of good health.

• 한국가금학회지
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• 제22권3호
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• pp.145-153
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• 1995

The root powder of Angelicae gigantis Radix (RPAGR) is known to he beneficial for liver and blood circulation. In a 6-wk broiler feeding trial, the RPAGR was added at levels of 0, 0.2, 0.5, and 1.0%, respectively. The RPAGR was found to be palatable as birds consumed moreof the test diets than the control(0% RPAGR) diet. The BW gain of 1.0% RPAGR group was higher than the control group. The feed efficiency(F/G) was improved significantly(P<0.01) by feeding 1.0% RPAGR. The RPAGR also caused beneficial effects in various carcass characteristics, i.e., carcass weight, dressing percentage, breast muscle, and thigh meat production. There was no consistent trend in various organ weights by the addition of RPAGR. Also, no consistent trend was found in abdominal fat weight. The serum cholesterol level tended to decrease as the BW increased. No consistent trend was detected in serum triglyceride contents.