• 제목/요약/키워드: blood

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혈당 조절 프로토콜 적용에 따른 흉부외과 중환자의 혈당 조절 상태와 혈당 변동 (The Effects of the Application of a Glucose Control Protocol on Glycemia and Glucose Variability in Critically Ill Cardiothoracic Surgery Patients)

  • 유혜진;이남주;이순행
    • 중환자간호학회지
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    • 제8권2호
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    • pp.1-12
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    • 2015
  • Purpose: The study sought to determine the state of blood glucose control, and the consequent clinical effects and variation in blood glucose level, of adult patients admitted to intensive care units following cardiothoracic surgery by comparing the blood glucose levels before and after the application of a blood glucose control protocol. Methods: The protocol was developed by modifying and supplementing the Yale protocol, and was first used in 2012. The resulting blood glucose data of an experimental group (n = 314), to which the blood glucose control protocol had been applied, and a control group (n = 347), whose blood glucose levels had been controlled according to physicians'prescriptions without the protocol, were collected through the medical records. Results: The target blood glucose ratio increased significantly in the experimental group, and the low blood glucose ratio decreased significantly in the experimental group. The two groups exhibited a significant difference (p < .001) in the degree of variation in the blood glucose levels. The duration of the use of a ventilator was significantly reduced in the experimental group (p < .001). Conclusion: It is expected that the protocol can be used for the safe and effective control of critically ill cardiothoracic surgery patients' blood glucose levels.

마이크로 PIV를 이용한 미세튜브 내부 조류 혈액유동에 관한 실험적 연구 (Experimental Investigation on Flow Characteristics of Chicken Blood in a Micro Tube Using a Micro-PIV Technique)

  • 여창섭;지호성;이상준
    • 대한기계학회논문집B
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    • 제30권11호
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    • pp.1027-1034
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    • 2006
  • In order to investigate flow characteristics of chicken blood in a micro tube of 100$\mu$m in diameter, in-vitro experiments were carried out using a micro-PIV technique. The micro-PIV system consists of a microscope, 2-head Nd:YAG laser, 12 bit cooled CCD camera and a delay generator. Chicken blood with 40% hematocrit was supplied into a micro tube using a syringe pump. The blood flow shows clearly the cell free layer near the tube wall and its thickness is increased with increasing the flow speed. The hemorheological characteristics of chicken blood, including shear rate and shear stress were estimated from the PIV velocity field data obtained. Since the aggregation index of chicken blood is less than 50% of human blood, non-Newtonian flow characteristics of chicken blood are smaller than those of human blood. As the flow rate increases, the degree of flatness in the velocity profile at the center region is decreased and the parabola-shaped shear stress distribution becomes to have a linear profile. Under the same flow rate, chicken blood shows higher shear stress, compared with human blood.

In-vitro study on the hemorheological characteristics of chicken blood in microcirculation

  • Ji, Ho-Seong;Lee, Jung-Yeop;Lee, Sang-Joon
    • Korea-Australia Rheology Journal
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    • 제19권2호
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    • pp.89-95
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    • 2007
  • The flow characteristics of chicken blood in a micro-tube with a $100{\mu}m$ diameter are investigated using a micro-Particle Image Velocimetry (PIV) technique. Chicken blood with 40% hematocrit is supplied into the micro-tube using a syringe pump. For comparison, the same experiments are repeated for human blood with 40% hematocrit. Chicken blood flow has a cell-free layer near the tube wall, and this layer's thickness increases with the increased flow speed due to radial migration. As a hemorheological feature, the aggregation index of chicken blood is about 50% less than that of human blood. Therefore, the non-Newtonian fluid features of chicken blood are not very remarkable compared with those of human blood. As the flow rate increases, the blunt velocity profile in the central region of the micro-tube sharpens, and the parabolicshaped shear stress distribution becomes to have a linear profile. The viscosity of both blood samples in a low shear rate condition is overestimated, while the viscosity in a high shear rate range is underestimated due to radial migration and the presence of a cell-depleted layer.

도축부산물인 돈혈의 재활용에 관한 연구 (Utilization of Slaughter Porcine Blood as an Animal Feed)

  • 김정학;박강희;류경선;이제훈
    • 한국축산시설환경학회지
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    • 제3권2호
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    • pp.133-143
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    • 1997
  • Optimal conditions for collecting, storing and drying temperature to utilize slaughter porcine blood for blood meals and the effects of blood meal on growth in broiler chicks were investigated. Dry matter and protein contents of slaughter procine blood were 19.5% and 77%(dry basis), respectively. As for the composites of amino acids in the blood, aspartic acid, arginine, glycine, histidine, leucine, lysine, phenylalanin threonine were shown high. There was no significant difference between the collections by bloodletting and vacuumming in terms of microbial contamination. Storage of slaughter porcine blood showed no differences in protein, DNA and triglyceride contents and pH between the storage methods of freezing (-20$^{\circ}C$) and refrigerating (-4$^{\circ}C$). In case of room temperature storage, however, the decrease in pH and the appearance of new protein due to microbial contaminations increased as the storage periods were prolonged. When drying was done by flash methods, the drying period got shortened as the temperature became higher, yet protein and triglyceride were destoryed more. When drying was done over 120$^{\circ}C$, even at the same degree, the breakdowns of protein and triglyceride increased more as drying period got longer. In feeding trials of broiler chicks, dietary supplementation of the flash dried blood meal at 2% level showed significant difference in growth rate(P<.05%). These results indicated that the appropriate handling and manufacturing of slaughter porcine blood enabled the blood to be used as a protein source for broiler chicks.

Hollow Fiber Oxygenator에서 Inside Blood Flow Type과 Outside Blood Flow Type의 임상적 비교 (Clinical Comparison Between Inside Blood Flow Type and Outside Blood Flow Type in the Hollow Fiber Oxygenator)

  • 안재호
    • Journal of Chest Surgery
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    • 제25권5호
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    • pp.451-457
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    • 1992
  • The hollow fiber oxygenator is the most advanced one for the cardiopulmoanry bypass. They have two different types of the hollow fiber systems according to the way how the blood go through the fibers. One is inside blood flow type and the other outside type. In order to find out which is better to prevent blood cell destruction, we selected 40 valve replacing patients and divided them into 2 groups prospectively. In group I [n=20], inside blood flow type[BCM-7a], CO2 excretion is more effective than group II, that is partly because of the relative large surface area of the BCM-7. In group II [n=20], outside blood flow type [MAXIMAa], they have better quality to preserve platelet count. We also studied about several other items such as SaO2, Hemoglobin and RBC, WBC, fibrinogen, LDH, plasma hemoglobin, haptoglobulin and so on. But we cannot find any differences between two groups with any statistical meanings [p<0.05]. We conclude that both of two oxygenators are excellent in the aspects of gas exchange and blood cell preservation.

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Examination of the Impact of Blood Groups on Group Participation

  • Asgari, Omid
    • 융합경영연구
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    • 제3권2호
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    • pp.9-20
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    • 2015
  • Could blood type provide a key to wellness and even affect our personality? The theory that blood type is linked to personality (and other mental and physical qualities) is popular mainly in Japan, though it has carried over to Taiwan and South Korea. The present study is the result of a scientific research in which the relationship between two important variables, namely blood group a nd group participation, are determined in the research framework. Based on some collected data from manufacturing firms which are accepted firms in Tehran Stock Exchange, and through cluster sampling a sample was selected. 380 questionnaires were distributed to the personnel of production line, of the firms then the reliability and validity of the questionnaires through independence test and average ratio comparison of the two population were examined, and through Pearson's chi-square formula, the relationship between blood group (independent variable) and group participation (dependent variable) were tested, then through Schuprow coefficient, the prioritization of blood groups over group participation was identified and the following results were obtained: people group participation is affected by their personality features which is derived from their temperament, mood, and characteristics. The study also showed that people blood groups has an effect on their group cooperation, and among blood groups, blood group A has the greatest tendency to group participation and then blood group O, AB, B are prioritized respectively.

일 지역 성인의 고혈압 유병률 및 관리 실태 (A Study on the Prevalence Rate of Hypertension and the Actual Conditions of Control)

  • 김현옥
    • 지역사회간호학회지
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    • 제10권1호
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    • pp.154-172
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    • 1999
  • In order to analyse the prevalence rate of hypertension and the actual conditions of control, we selected five districts out of eleven eups and myuns in Chinan Country. We administered structured questionaries to 309 adults above the age of 40, computerized the data using SPSS - PC+. More than 40.1% of adults over 40 in Chinan County have health disorders ranging from high blood pressure to hypertension including alert high blood pressure at 36.2%, relatively high. Among general characteristics, differences in the rate of hypertension were influenced by age, occupation and places of residence. Over 71 who are engaged in agriculture, who don't have jobs, who reside in Sungsu, Jungchun, Chinan-eup all have higher hypertension rates than other groups. Accordingly, the control of hypertension should be focused on these people. As a result of the control of blood pressure, the survey showed 93.0% of the subjects were checked mainly at hospitals clinics, health centers subhealth centers and community health posts more than once a year, relatively high level of blood pressure management. However, the difference between their blood pressure measurements at ordinary times and the level of blood pressure at the time of research was quite considerable. Only 47.3% of the subjects diagnosed with high blood pressure and 70.3% of the subjects with normal blood pressure recognized their blood pressure accurately 52.7% of the subjects diagnosed with high blood pressure showed errors in understanding their blood pressure at normal times. Because these errors can cause problems in the control of blood pressure, proper management should be executed through a systematic examination. As a result of the high blood pressure control condition, the average period of hypertension was 74.5( ${\pm}92.8$) months, 92.3% of the subjects were diagnosed with high blood pressure at hospitals clinics, health centers subhealth centers community health posts, but only 29.5% were examined after a general check up on high blood pressure was completed. 70.5% were diagnosed with high blood pressure only after measuring their blood pressure. 14.1% of the subjects were hospitalized because of falls influenced by high blood pressure. 33.3% attended hospitals and health centers regularily for medical treatment and this shows how low the rate of the control of blood pressure. Most people did not undergo medical treatment, because they had no painful symptoms (46.7%), they didn't need to take the medicine(28.9%), or they forget to take the medicine(20.0%). These problems in the control of hypertension were discovered in the process of diagnosing high blood pressure at health medical institutions. Many people did not recognize the need for consistent control of blood pressure. That is, although the diagnosis for high blood pressures performed at hospitals clinics, health centers subhealth centers and community health posts, was 92.3%, more than 70.5% of the subjects were not examined completely with regard to blood pressure. Accordingly, heath medical institutions must diagnose high blood pressure not only by only measuring blood pressure but also by using systematic process of examination. As for the people diagnosed with high blood pressure, one should perform consistent medical approaches and help them to recognize the importance of the continuous control of blood pressure through subject-oriented education. Problems the subjects experienced were the following numbness in the limbs easily paralyzed stitches in their shoulders which felt painful, stiff necks, occiputs felt heavy, headaches when they got up in the morning, felt dizzy when standing and moving their heads and poor eyesight. The rate of knowledge related to high blood pressure was 78.7 points, comparatively low. Whether they had normal blood pressure or hypertension made no difference. These results are not desirable. Adult-oriented education forgot the prevention and management of high blood pressure should be implemented. Hypertensive-oriented education should be especially reinforced. Because there was a difference in the level of knowledge according to age, academic career, occupation or place of residence, education related to hypertension should be intensified and focused on those over the age of 71 those who did not attend school, those who do not have jobs and are engaged in agriculture and residents living in Bugui, Jungchun regions. The degree of healthy life practice in hypertensives is poor, particularly weight control, as opposed to people who have normal blood pressure. It makes no difference in smoking, the amount of daily smoking, drinking, the control of salt because each result means that they are not practicing healthy life or modifying their life-style. The development and programs to improve a healthy life should be executed.

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내당능장애 가능성이 있는 중년 남성의 신체적 특성, 영양소 섭취상태 및 혈중 지질농도 양상 (The Nutritional Status of Middle Aged Korean Men Exhibiting Impaired Glucose Tolerance and Their Blood Lipid Profile)

  • 양윤정;김진옥
    • Journal of Nutrition and Health
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    • 제33권1호
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    • pp.59-67
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    • 2000
  • The objective of this study was to investigate nutritional status of middle aged Korean men exhibiting impaired glucose tolerance (IGT) and identify the risk factors related to IGT Data were collected from 163 men with a fasting blood glucose level from 115 to 139mg/dl(high blood glucose group: HBG) and 170 men with a normal fasting blood glucose level(control) aged from 40 to 59 years in both groups. Weight, body mass index(BMI) and percent body fat were significantly higher in high blood glucose(HBG) group than those of control group. Age, weight, BMI, percent body fat were positively related to blood glucose. There were no differences in exercise, smoking and family history of diabetes between two groups. Frequency of fat eating and overeating of HBG were higher than those of control group but frequency of sweet snacks intake of HBG was lower than that of control group. There was no difference in daily total energy intake in two groups. Total and supper energy intakes were positively associated with blood glucose. Percent energy intake of alcohol was significantly higher in HBG group and positively related to blood glucose, however there were no difference in daily intake of nutrients in two groups. Alcohol intake was positively related to BMI, but after adjusting BMI, there was no correlation between alcohol intake and blood glucose. Serum total cholesterol and triglyceride were significantly higher in HBG group than those of control group. Serum total cholesterol i,nd triglyceride were positively related to blood glucose and high density lipoprotein cholesterol was negatively associated with blood glucose. After adjusting BMI, serum triglyceride was positively related to blood glucose. In conclusion, weight, BMI, percent body fat and blood total cholesterol, low density lipoprotein cholesterol and triglyceride levels were positively related to blood glucose level of middle aged Korean men exhibiting impaired glucose tolerance. Their eating habits exhibited higher frequency of overeating, fast eating, high energy intakes of supper. (Korean J Nutrition 33(1) : 59-67, 2000)

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The Relationships Among Body Fat Distribution, Blood Pressure, Blood Lipids and Exercise in Healthy Men and Women

  • 최미자
    • 동아시아식생활학회지
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    • 제3권2호
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    • pp.29-40
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    • 1993
  • A variety of studies show that a centraized rather than a generalized pattern of subcutaneous fat distribution is more directly associated with disorers of carbohydrate and lipid metabolism, as possibly hypertension, This study was an attempt to observe the relationship of body fat distribution, blood lipids, blood pressure and exercise in 85 healthy men and women. Within this group there was a gradation of fat distribution progressing from LBSO and UBSO defined on the basis of WHR. This paper reports the relationship of body fat distribution defined by WHR to plasma glucose, lipids, blood pressure, and exercise in this population. Although the obesity indices(RBW and BMI) were slightly higher in the UBSO group, significant differences existed between UBSO and LBSO groups with respect to WHR blood pressure, and total cholesterol concentration in female. WHR values were substantially different and this was primarily due to greater degrees of differences in waist as opposed to hips circum ference. Although no significant differences existed between UBSO and LBSO groups with respect to age, body weight, and hips circumference, energy intake, total cholesterol, LDL-cholesterol and WHR values were substantially different in male. Positive, significant correlations were found between WHR and both systolic and diastolic blood pressure and between WHR and the total plasma cholesterol concentration and age. When 26 pairs of exercise and nonexercise groups were matched according to sex, age and body weight, blood pressure and blood lipids were significantly lower in the exercise groups than those in the nonexercise groups. In conclusion, these findings suggest that an altered blood lipid profiles will manifast in men and women with upper body obese. Furthermore these findings suggest that exercise and physical activity may be beneficial for controlling blood lipids and blood pressure in healthy adults.

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Korean Red Ginseng Protects Oxidative Injury Caused by Lead Poisoning

  • Park, Myoung-Soo;Cho, Eun-Jung;Lee, Sang-Ki;Lee, Eun-Ji;Lee, Dae-Sik;Lee, Kwon-Ho;Jeon, Byeong-Hwa
    • Journal of Ginseng Research
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    • 제34권2호
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    • pp.132-137
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    • 2010
  • Lead (Pb) is a metal that is generally considered to be toxic to the cardiovascular system. Pb-exposed animals display the evidence of increased oxidative stress and hypertension. The current study was designed to examine whether Korean red ginseng (KRG) has protective effects against Pb-induced hypertension and oxidative stress in Pb-exposed rats. Male Sprague-Dawley rats were randomly assigned to Pb exposure or control groups. KRG was administered in drinking water at a concentration of 100 mg/kg/day; the control group received plain drinking water. Animals in the Pb-exposed groups were provided with drinking water containing 100 ppm Pb acetate for 12 weeks. Blood pressure, plasma glutathione, blood Pb concentration, and hematologic data, such as red blood cell quantity, were determined. Pb poisoning was assessed by measuring the blood Pb concentration. Pb exposure (100 ppm) for 12 weeks resulted in a marked rise in systolic blood pressure and blood Pb concentration, as well as a significant reduction in plasma glutathione levels and red blood cell quantity. Other measurements, such as heart rate, body weight, and white blood cell quantity, were unchanged. Treatment with KRG significantly lowered blood pressure, raised plasma glutathione and increased red blood cell numbers in Pb-exposed animals; it also had no effect on heart rate, body weight, or white blood cell quantity. However, the elevated blood Pb concentration was not reduced by treatment with KRG (100 mg/kg). Taken together, these data indicate that treatment with KRG in Pb-exposed animals can reduce oxidative stress and lower blood pressure, suggesting that KRG might be protective against Pb-exposed hypertension and oxidative stress.