• Title/Summary/Keyword: blood

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Ultrasound Backscattering from Erythrocyte Aggregation of Human, Horse and Rat Blood under Rotational Flow in a Cylindrical Chamber

  • Nam, Kweon-Ho;Paeng, Dong-Guk;Choi, Min-Joo
    • The Journal of the Acoustical Society of Korea
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    • v.25 no.4E
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    • pp.159-165
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    • 2006
  • Human, horse and rat bloods in a cylindrical chamber where flow was controlled by a stirring magnet were used for studying red blood cell aggregation. Ultrasound backscattered powers from blood were obtained from the backscattered signals measured by a 5 MHz focused transducer in a pulse-echo setup. The experimental results showed the differences in red blood cell (RBC) aggregation tendency among the three mammalian species with an order of horse > human > rat. The ultrasound backscattered power decreased with stirring speed in human and horse blood, but no variations were observed in rat blood. Sudden flow stoppage led to the slow increase of the backscattered power for human and horse blood. There was no self-aggregation tendency in rat blood. The enveloped echo images showed the spatial and temporal variations of RBC aggregations in the cylindrical chamber. These observations from the different mammalian species may give a better understanding of the mechanism of RBC aggregation.

The Effects of Interferential Current Therapy on Blood Flow in upper limbs (간섭 전류 자극이 상지 혈류변화에 미치는 영향)

  • Park Rae-joon;Park Young-han
    • The Journal of Korean Physical Therapy
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    • v.15 no.4
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    • pp.140-150
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    • 2003
  • The purpose of study was to compare change of blood volume on upper limb of stimulus site on interferential current therapy. Twenty university student(twelve females. eight males :mean aged 23.08) with health condition participated this study MP150 system(biopac system) was used to measured blood volume. PPG senser was located thrum finger end The obtain result are as follows. 1. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 2. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 3. The result of this study were following that sympathetic stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05). 4. The result of this study were following that muscle stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05).

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Effects of Autotransfusion using Cell Saver in Cardiac Surgery (개심술시 자가 수혈체계[Cell Saver]의 이용 효과)

  • 안욱수
    • Journal of Chest Surgery
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    • v.25 no.11
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    • pp.1312-1317
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    • 1992
  • Autologous blood transfusion is a common method of reducing the need for homologous blood transfusion during cardiac operations. Between June 1991 and May 1992, 12 cases [Group I] were experienced autologous blood transfusion using Cell Saver undergoing double valve replacement or redo-valve replacement. Control group [N=12, Group II] was selected to above similar operation during same period. The Cell Saver system [Haemonetics Corp.] was employed for autologous blood transfusion. The blood shed in the operative field before and after cardiopulmonary bypass and remained cardiotomy reservior was aspirated by means of a locally heparinized collecting system. After centrifused salvaged blood, the resulting red cell concentrate reinfused subsequently. The patient receiving autologous blood transfusion required significantly less homologous blood transfusion than their control group. [Group I; 3519 $\pm$ 869, Group II; 4622 $\pm$ 856, Respectively; P=0.005] There were no clinical infections in the autotransfusion group. And there was no apparent intergroup difference of the clinical findings, hematologio datas and coagulation parameters. We conclude the autotransfusion using Cell Saver is effective for reducing of the hom-ologlous blood transfusion in cardiac surgery.

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Correlation between Rouleau Condition of Red Blood Cell on Live Blood Analysis and Degree of Fatigue (생혈액검사상 적혈구의 연전현상과 피로도와의 상관관계)

  • Shin, Seung-Uoo;Lee, Jong-Soo
    • The Journal of Korea CHUNA Manual Medicine
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    • v.2 no.1
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    • pp.159-168
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    • 2001
  • Objectives : It is known that rouleau condition of red blood cell on live blood analysis is related to degree of fatigue. This study was planed to prove the correlation between rouleau condition of red blood cell and degree of fatigue by using the questionnaire 'Symptom Table on Fatigue Perception' that had been verified before. Methods : We analyzed the correlation between rouleau condition and degree of fatigue by calculating ratio of rouleau of red blood cell after measuring degree of fatigue by the questionnaire to the people who had not evidence of illness on health examination and did not take any medicine. Results and Conclusions : This study showed a significance of positive correlation(0.464) between physical fatigue and rouleau condition of red blood cell.

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Assessment of Ventricular Function Using Gated Blood Pool Scan and Gated Blood Pool SPECT (게이트심장혈액풀 스캔과 게이트심장혈액풀 SPECT를 이용한 심실기능의 평가)

  • Park, Seok-Gun
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.2
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    • pp.100-106
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    • 2005
  • Non-invasive evaluation of cardiac function by nuclear medicine technologies are one of the major contribution of nuclear medicine. Gated cardiac blood pool scan was once a novel and robust technique which enabled evaluation of ventricular function. Concept of EKG gating was one of the major breakthrough in nuclear cardiology. According to the evolution of echocardiographic techniques, and as the evaluation of myocardial perfusion by perfusion SPECT became feasible, number of gated blood pool study dong in nuclear medicine laboratory is declining. And recently, evaluation of ventricular function with gated perfusion SPECT further decreased the use of gated blood pool scan. In this article, assessment of ventricular function using gated blood pool scan is discussed including some insight about the role of gated blood pool SPECT.

Large Cohort Association of Single Nucleotide Polymorphism of PLA2G4A Gene with White Blood Cell Counts in Korean Population

  • Jung, Suk-Yul
    • Biomedical Science Letters
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    • v.18 no.1
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    • pp.71-75
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    • 2012
  • The PLA2G4A catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid, which is metabolized into lipid-based cellular hormones that regulate inflammatory response. The circulating blood cell numbers can be influenced by stress, infection or inflammation. Quantitative blood cell count traits analysis for the 19 SNPs in the PLA2G4A gene in the Korean Association Resource (KARE) cohort (7551 subjects) was performed. The only one SNP (rs10752979) in the all blood cell count was satisfied with the Bonferroni corrected P-value (<0.00263). Furthermore, 6 of the 19 SNPs in the PLA2G4A gene showed a weak or moderate association with blood cell count (P-values: 0.0048~0.042), suggesting the clue of an association between the PLA2G4A gene and blood cell count, especially white blood cell count. This study may provide insight into the genetic basis of blood cell count related with reaction of infection.

Intraoperative and Postoperative Blood Conservation in Cardiac Surgery (수술중 및 수술후 혈액보존법)

  • 이재원
    • Journal of Chest Surgery
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    • v.27 no.6
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    • pp.451-454
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    • 1994
  • In February 1991 I initiated a blood conservation program that included hemodilution, use of a cell conservation device to concentrate diluted blood from operative field and from mediastinal shed blood, acceptance of a minimal hematocrit level of 25% in stable patients, and strict avoidance of use of blood products without definitive indication. A retrospective study to evaluate the effects of blood conservation program was designed to compare the amount of homologous transfusion, hematologic data, and postoperative outcome in patients operated on before and after initiation of blood conservation program. Patient characteristics were not different between two groups, before[n = 18] and after[n = 42] initiation of the program. The significant decrease of homologous transfusion[5.2 vs 1.4 units] and the marked increase of nontransfused patients[none vs 57%] in experimental group were due to marked decrease in homologous transfusion during the operation[4.6 vs 0.7 unit]. I conclude that with strict intraoperative blood conservation program, cardiac patients can be operated on with minimal homologous transfusion.

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A Collaborative Study to Establish a Korea National Biological Standard for Antithrombin III Concentrate

  • Kang, Hye-Na;Oh, Ho-Jung;Kim, Soon-Nam;Hong, Choong-Man;Lee, Ki-Hong;Yoo, Si-Hyung;Shin, In-Soo;Choi, Seung-Eun;Lee, Seok-Ho
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.149.2-149.2
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    • 2003
  • We have carried out a collaborative study to evaluate a candidate preparation of antithrombin III concentrate whether it is suitable to serve as a Korea National Biological Standard. Three National Control Laboratories and three manufacturers participated in this study. The potency of this candidate preparation was determined by using a heparin cofactor chromogenic method described in the Minimum Requirements for Biological Products and the European Phamacopoeia. (omitted)

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A study on the evaluation of artificial cartilage using synthetic biodegradable polymers

  • Oh, Ho-Jung;Lee, Nam-Kyung;Kim, Soon-Nam;Hong, Choong-Man;Lee, Ki-Hong;Yoo, Si-Hyung;Shin, In-Soo;Lim, Jae-Hyun;Choi, Seung-Eun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.100.1-100.1
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    • 2003
  • Tissue engineering has arisen to address the extreme shortage of tissues and organs for transplantation and repair. One of the most successful techniques has been the seeding and culturing cells on three-dimensional biodegradable scaffolds in vitro followed by implantaion in vivo. We used PLA and PLGA as biodegradable polymers and rabbit chondrocytes were isolated and applied to PLA and PLGA to make artificial cartilage. To evaluate the biocompatibility and biological safety of polymers, in vitro cytotoxicity and in vivo animal tests were investigated. (omitted)

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Classification of White Blood Cell Using Adaptive Active Contour

  • Theerapattanakul, J.;Plodpai, J.;Mooyen, S.;Pintavirooj, C.
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.1889-1891
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    • 2004
  • The differential white blood cell count plays an important role in the diagnosis of different diseases. It is a tedious task to count these classes of cell manually. An automatic counter using computer vision helps to perform this medical test rapidly and accurately. Most commercial-available automatic white blood cell analysis composed mainly 3 steps including segmentation, feature extraction and classification. In this paper we concentrate on the first step in automatic white-blood-cell analysis by proposing a segmentation scheme that utilizes a benefit of active contour. Specifically, the binary image is obtained by thresolding of the input blood smear image. The initial shape of active is then placed roughly inside the white blood cell and allowed to grow to fit the shape of individual white blood cell. The white blood cell is then separated using the extracted contour. The force that drives the active contour is the combination of gradient vector flow force and balloon force. Our purposed technique can handle very promising to separate the remaining red blood cells.

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