• Title/Summary/Keyword: bleeding risk

Search Result 355, Processing Time 0.021 seconds

Analysis of premature death of Sprague-Dawley rats in carcinogenicity studies

  • Son, Woo-Chan;Kim, Bae-Hwan
    • Korean Journal of Veterinary Research
    • /
    • v.44 no.3
    • /
    • pp.373-378
    • /
    • 2004
  • To help the interpretation of causes of death, it is critical that the background incidence of factors contributing to death be recorded and archived. Information was gathered from the control groups of 19 rat carcinogenicity studies. All cases of death occurring within the 2-year period were reviewed. Out of 1124 males and 1084 females, 720 male (64.1%) and 689 female (63.6%) decedents were recorded. There was no difference in the probability of survival between two sexes. Analysis of factors contributing to death revealed that 400 males (48.7%) had neoplastic changes, 189 males (23.0%) had non-neoplastic lesions, and 232 males (28.3%) died from unknown causes. In females, these figures were 627 (76.4%), 62 (7.6%) and 132 (16.0%), for neoplastic, non-neoplastic and unknown findings, respectively. It could be suggested that the risk of death by non-neoplastic reasons was higher in the males than in the females, whereas females were more likely to be affected by tumours. In the neoplastic causes of death, pituitary tumours were the most common in both sexes, followed by mammary tumours in females, and haemopoietic tumours in males. In non-neoplastic cause of death, renal diseases were the most common in both sexes, followed by skin diseases and cardiovascular diseases in males, and skin diseases and poditis in males. A relatively large number of animals (28.3% in males and 16.0% in females) were found dead, without any significant clinical or histologically identifiable cause. Most of the animals with pituitary tumours were killed in extremis and the proportion of females (70.1%) being greater than males (46.8%). There were no case which died by accident, and also only minimal incidence which died by bleeding procedures.

A Study on the Relationship between Oral Health Promotion Behavior and Oral Symptoms According to Dietary Life of Adolescents (청소년들의 식생활에 따른 구강건강증진행위와 구강증상과의 관련성 융합연구)

  • Park, Sin-Young;Lim, Sun-A
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.11
    • /
    • pp.251-256
    • /
    • 2020
  • This study aims to investigate the relationship between oral health promotion behavior and oral symptoms according to the dietary life of adolescents through the 15th(2019) online survey of Youth Health Behavior. According to the study, the number of tooth brush(day) was significant with all dietary life, caffeine and eating habit education experience were significant with all oral health promotion behavior, use of oral health device was significant with fruit, vegetable, sealant experience was significant with fruit, fastfood, vegetable, scaling experience was significant with fruit and oral education experience was significant with fruit, soda, fastfood, vegetable. Toothbreak was significant fruit, soda, fastfood, pain and bleeding were significant with caffeine, fastfood, vegetable, eating habit education experence, bad breath was significant with fruit, caffeine, vegetable. Therefore, dietary life should be considered for the management of oral health promotion behaviors and oral symptoms of adolescents.

Relationship between maternal periodontal disease and Apgar score of newborns

  • Shirmohammadi, Adileh;Abdollahifard, Sedigeh;Chitsazi, Mohammad-Taghi;Behlooli, Sepideh
    • Journal of Periodontal and Implant Science
    • /
    • v.42 no.6
    • /
    • pp.212-216
    • /
    • 2012
  • Purpose: The aim of this study was to evaluate the relationship between maternal periodontal disease and the health status of newborns using Apgar scores. Methods: One hundred pregnant women with periodontal disease were included in the case series and 100 pregnant women without periodontal disease were placed in the control group, respectively. The periodontal parameters of bleeding on probing (BOP), clinical attachment loss (CAL), probing depth (PD), birth weight, and Apgar scores were recorded in both groups. T-tests and Pearson's correlation coefficient were used to determine the birth weight odds ratio to analyze the relationship between the periodontal parameters of BOP, CAL, and PD on the one hand and an Apgar score of less than 7. An unpaired Student's t-test was used to analyze differences in means between the case and control groups using SPSS ver. 13. Results: The means of the ages, periodontal pocket depths, attachment loss, areas with BOP, Apgar score in the first 5 minutes and infant birth weight exhibited statistically significant differences between the case and control groups. The ratio of an Apgar score of <7 to periodontal disease was 3.14; the ratio of low birth weight risk in mothers with periodontal disease to that in mothers without periodontal disease was 2.74. Pearson's correlation coefficient revealed a significant correlation between the infant birth weight and BOP, CAL, and PD of the mother. In addition, there was a significant correlation between the Apgar score and BOP, CAL, and PD and also between the Apgar score and infant birth weight. Conclusions: The results of this study showed a significant relationship between periodontal disease and infant birth weight; in addition, there was a significant relationship between the periodontal indexes of BOP, CAL, and PD on the one hand and the Apgar score on the other.

The Infection Control of Dental Impressions (치과용 인상체의 감염 관리)

  • Lee, Jin-Han
    • Journal of Dental Rehabilitation and Applied Science
    • /
    • v.29 no.2
    • /
    • pp.183-193
    • /
    • 2013
  • The characteristics of dental treatment makes the dental staff frequently contact with patient directly. Also the daily use of high-handpieces, sharp instruments, and needles often causes bleeding on oral cavity. Therefore, the risk of cross transmission grows up. The pathogen from dental practice could spread on not only the practice itself but also the dental laboratory with contaminated impressions and prosthesis. Dental clinic staffs (dentists, dental hygienists and dental technicians) should recognize all the patients have a possibility of cross contamination, and try to prevent the transmission of infection by proper infection control. In this study, we review the articles about disinfection methods and chemical infection agents used for dental impressions, and try to figure out the suitable and effective infection control system of dental impressions.

Clinical and Microbiological Study about Efficacy of Air-polishing and Scaling and Root-planing

  • Yang, Keon-Il;Park, Do-Young;Kim, Byung-Ock;Yu, Sang-Joun
    • International Journal of Oral Biology
    • /
    • v.40 no.2
    • /
    • pp.93-101
    • /
    • 2015
  • The efficacy of air-polishing on subgingival debridement, as compared to scaling and root planning (SRP), was evaluated clinically and microbiologically. Fifteen patients diagnosed as chronic periodontitis, and having single-root tooth over 5 mm of pocket depth symmetrically in the left and right quadrant, were investigated. Subgingival debridement was performed by SRP and air-polishing. The results were evaluated and compared clinically and microbiologically. Probing pocket depth (PPD), bleeding on probing (BOP), relative attachment level (RAL) and change of gingival crevicular fluid (GCF) were assessed before treatment, and at 14 and 60 days after treatment. Microbial analysis was done pre-treatment, post-treatment, and at 14 and 60 days after treatment. Results of air polishing showed that post treatment, the PPD and BOP decreased, and attachment gain was observed. There was no clinical difference when compared to SRP. The volume of GCF decreased at 14 days, and increased again at 60 days. Compared to SRP, there was a statistical significance of the volume of GCF at 60 days in air-polishing. In the microbial analysis, high-risk bacteria that cause periodontal disease were remarkably reduced. They decreased immediately after treatment, but increased again with the passage of time. Thus, our results show that subgingival debridement by air-polishing was effective for decrease of pocket depth, attachment gain, decrease of GCF and inhibition of pathogens. Further studies are required to compare air-polishing and SRP, considering factors such as degree of pocket depth and calculus existence.

A Case of Trousseau's Syndrome Associated with Lung Cancer (폐암과 동반된 Trousseau 증후군 1예)

  • Song, Min-Kyung;Kim, Young-Sam;Lee, Kee-Myung;Kim, Se-Kyu;Chang, Joon;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
    • /
    • v.42 no.6
    • /
    • pp.941-946
    • /
    • 1995
  • The association between hypercoagulability and malignant disease was first described by Armand Trousseau in 1865. According to Trousseau, the thrombophlebitis was usually/migratory and recurrent and involved both venous and arterial system. Thrombosis remains the hallmark of Trousseau's syndrome, although a wide variety of coagulation disorders including disseminated intravascular coagulation(DIC), pulmonary embolism, thrombotic endocarditis, and bleeding have been associated with the syndrome. Since then, abnormalities of the coagulation system have been repeatedly demonstrated in patients with cancer. Pancreatic carcinoma is thought to carry the highest risk of Trousseau's syndrome although the number of cases of Trousseau's syndrome is actually higher in patients with lung cancer because of the greater prevalence of this tumor. We report a thirty-five year old male patient with Trousseau's syndrome associated with lung cancer initially presenting deep vein thrombosis.

  • PDF

Prevalence of Porphyromonas gingivalis fimA genotypes in peri-implant sulcus of Koreans using new primer

  • Kim, Sung-Geun;Hong, Ji-Youn;Shin, Seung-Il;Moon, Ji-Hoi;Lee, Jin-Yong;Herr, Yeek
    • Journal of Periodontal and Implant Science
    • /
    • v.46 no.1
    • /
    • pp.35-45
    • /
    • 2016
  • Purpose: Porphyromonas gingivalis fimA is a virulence factor associated with periodontal diseases, but its role in the pathogenesis of peri-implantitis remains unclear. We aimed to evaluate the relationship between the condition of peri-implant tissue and the distribution of P. gingivalis fimA genotypes in Koreans using a new primer. Methods: A total of 248 plaque samples were taken from the peri-implant sulci of 184 subjects. The control group consisted of sound implants with a peri-implant probing depth (PD) of 5 mm or less with no bleeding on probing (BOP). Test group I consisted of implants with a peri-implant PD of 5 mm or less and BOP, and test group II consisted of implants with a peri-implant PD of more than 5 mm and BOP. DNA was extracted from each sample and analyzed a using a polymerase chain reaction (PCR) with P. gingivalis -specific primers, followed by an additional PCR assay to differentiate the fimA genotypes in P. gingivalis-positive subjects. Results: The Prevalence of P. gingivalis in each group did not significantly differ (P>0.05). The most predominant fimA genotype in all groups was type II. The prevalence of type Ib fimA was significantly greater in test group II than in the control group (P<0.05). Conclusions: The fimA type Ib genotype of P. gingivalis was found to play a critical role in the destruction of peri-implant tissue, suggesting that it may be a distinct risk factor for periimplantitis.

The Reliability of the Transconjunctival Approach for Orbital Exposure: Measurement of Positional Changes in the Lower Eyelid

  • Yoon, Sung Ho;Lee, Jin Hoon
    • Archives of Craniofacial Surgery
    • /
    • v.18 no.4
    • /
    • pp.249-254
    • /
    • 2017
  • Background: Lower eyelid incisions are widely used for the orbital approach in periorbital trauma and aesthetic surgery. In general, the subciliary approach is known to cause disposition of the lower eyelid by scarring the anterior lamella in some cases. On the other hand, many surgeons believe that a transconjunctival approach usually does not result in such complications and is a reliable method. We measured positional changes in the lower eyelid in blowout fracture repair since entropion is one of the most serious complications of the transconjunctival orbital approach. Methods: To measure the positional changes in the lower eyelids, we analyzed preoperative and postoperative photographs over various time intervals. In the analysis of the photographs, marginal reflex distance 2 ($MRD_2$) and eyelash angle were used as an index of eyelid position. Statistical analyses were performed to identify the significance in the positional changes. All patients underwent orbital reconstruction through a transconjunctival incision by a single plastic surgeon. Results: In 42 blowout fracture patients, there was no statistical significant difference in the MRD2 and eyelash angle. Furthermore, there were no clinical complications, such as infection, hematoma, bleeding, or implant protrusion, during the follow-up periods. Conclusion: The advantages of the transconjunctival approach for orbital access include minimal scarring and a lower risk of eyelid displacement compared with other approaches. Based on these results, we recommend the transconjunctival approach for orbital exposure as a safe and reliable method.

ORIGINAL ARTICLE - Considerations for Periodontal Treatment and Implant Therapy in Smoking Patient (ORIGINAL ARTICLE - 흡연 환자에서의 치주치료와 임플란트 수술)

  • Park, Jung-Chul;Hwang, Ji-Wan;Jung, Ui-Won;Kim, Chang-Sung;Cho, Kyoo-Sung;Choi, Seong-Ho
    • The Journal of the Korean dental association
    • /
    • v.49 no.10
    • /
    • pp.618-627
    • /
    • 2011
  • Cigarette smoking is a significant risk factor for periodontaldiseases and implant treatments. Smoking control is regarded as a key to the success of dental treatments as well as the well-being of the patients. The aim of this study was to reviewthe effects of smoking on periodontal health, and the results of periodontal therapy and implant treatments. Also, in vitro, microbiological, immunological and epidemiological relationships were studied. In vitro studies show that smoking interferes with normal healing process and increased tissue destruction. There is still controversy on the population of microbes of smokers. Smokers showed significantly less gingival inflammation and bleeding on probing compared with non-smokers. After periodontal treatments, a compromised clinical outcome was noted for smokers in terms of pocket depth reduction and gain in attachment levels. In conclusion, data from in vitro, epidemiological, cross-sectional and case-control studies strongly suggest that quitting smoking is beneficial to patients before periodontal and implant treatments.

The associated factors with subjective oral symptoms experience in obesity adolescent (비만 청소년의 주관적 구강증상경험 관련 요인)

  • Park, Sin-Young
    • Journal of Korean society of Dental Hygiene
    • /
    • v.17 no.5
    • /
    • pp.757-767
    • /
    • 2017
  • Objectives: The purpose of this study is to identify the associated factors with subjective oral symptoms experience of obesity adolescents. Methods: The study subjects were targeting 8,139 obesity adolescents and 55,601 non-Obesity adolescents who completed 2016 Korean Youth Risk Behavior Web-based survey. Dependent variables were subjective oral symptoms experiences of fracture teeth, pain, throbbing pain, periodontal pain & bleeding, mucosal disease and bad breath. Independent variables were demographic characteristics of the subjects, oral health behaviors, health behaviors and eating habits. Results: Obesity adolescents were 12.8% with 61.9% subjective oral symptoms experience. Regarding the related factors of subjective oral symptoms experience of obesity adolescents, the factors were identified to be significantly higher in high school (OR=1.72) compared to middle school, learning achievement was higher in middle (OR=1.09) and lower (OR=1.31) compared to high, economic status was higher in lower (OR=1.09) compared to high, sealant experience (OR=1.10) and scaling experiences (OR=1.12) responded no were higher compared to responded yes, smoking experiences responded yes(OR=1.08) were higher compared to responded no, sweet drink (OR=1.14) and fastfood (OR=1.13) consumption were higher in consumption compared to non-consumption and females (OR=0.46) were higher than males. Oral symptoms experience were lower that father and mother's level of education were under high school graduation (OR=0.86) compared to unknown, economic status was in case of middle (OR=0.93) compared to high, tooth brushing was lower in under 1 time (OR=0.76), 2 times (OR=0.61) compared to more than 3 times, vigorous physical activities responded no (OR=0.75) were lower, compared to yes, vegetable consumption was lower in non-consumption (OR=0.68) compared to consumption. Conclusions: Subjective oral symptoms experiences were identified higher in obesity adolescents than non-obesity adolescents. It would be useful to use the results of this study to reduce oral symptoms and necessary to develop a program system considering characteristics of obesity adolescents.