• Title/Summary/Keyword: blast analysis

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Performance Improvement of BLAST using Grid Computing and Implementation of Genome Sequence Analysis System (그리드 컴퓨팅을 이용한 BLAST 성능개선 및 유전체 서열분석 시스템 구현)

  • Kim, Dong-Wook;Choi, Han-Suk
    • The Journal of the Korea Contents Association
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    • v.10 no.7
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    • pp.81-87
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    • 2010
  • This paper proposes a G-BLAST(BLAST using Grid Computing) system, an integrated software package for BLAST searches operated in heterogeneous distributed environment. G-BLAST employed 'database splicing' method to improve the performance of BLAST searches using exists computing resources. G-BLAST is a basic local alignment search tool of DNA Sequence using grid computing in heterogeneous distributed environment. The G-BLAST improved the existing BLAST search performance in gene sequence analysis. Also G-BLAST implemented the pipeline and data management method for users to easily manage and analyze the BLAST search results. The proposed G-BLAST system has been confirmed the speed and efficiency of BLAST search performance in heterogeneous distributed computing.

NBLAST: a graphical user interface-based two-way BLAST software with a dot plot viewer

  • Choi, Beom-Soon;Choi, Seon Kang;Kim, Nam-Soo;Choi, Ik-Young
    • Genomics & Informatics
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    • v.20 no.3
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    • pp.36.1-36.6
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    • 2022
  • BLAST, a basic bioinformatics tool for searching local sequence similarity, has been one of the most widely used bioinformatics programs since its introduction in 1990. Users generally use the web-based NCBI-BLAST program for BLAST analysis. However, users with large sequence data are often faced with a problem of upload size limitation while using the web-based BLAST program. This proves inconvenient as scientists often want to run BLAST on their own data, such as transcriptome or whole genome sequences. To overcome this issue, we developed NBLAST, a graphical user interface-based BLAST program that employs a two-way system, allowing the use of input sequences either as "query" or "target" in the BLAST analysis. NBLAST is also equipped with a dot plot viewer, thus allowing researchers to create custom database for BLAST and run a dot plot similarity analysis within a single program. It is available to access to the NBLAST with http://nbitglobal.com/nblast.

A Pattern Summary System Using BLAST for Sequence Analysis

  • Choi, Han-Suk;Kim, Dong-Wook;Ryu, Tae-W.
    • Genomics & Informatics
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    • v.4 no.4
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    • pp.173-181
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    • 2006
  • Pattern finding is one of the important tasks in a protein or DNA sequence analysis. Alignment is the widely used technique for finding patterns in sequence analysis. BLAST (Basic Local Alignment Search Tool) is one of the most popularly used tools in bio-informatics to explore available DNA or protein sequence databases. BLAST may generate a huge output for a large sequence data that contains various sequence patterns. However, BLAST does not provide a tool to summarize and analyze the patterns or matched alignments in the BLAST output file. BLAST lacks of general and robust parsing tools to extract the essential information out from its output. This paper presents a pattern summary system which is a powerful and comprehensive tool for discovering pattern structures in huge amount of sequence data in the BLAST. The pattern summary system can identify clusters of patterns, extract the cluster pattern sequences from the subject database of BLAST, and display the clusters graphically to show the distribution of clusters in the subject database.

A performance based strategy for design of steel moment frames under blast loading

  • Ashkezari, Ghasem Dehghani
    • Earthquakes and Structures
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    • v.15 no.2
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    • pp.155-164
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    • 2018
  • Design of structures subjected to blast loads are usually carried out through nonlinear inelastic dynamic analysis followed by imposing acceptance criteria specified in design codes. In addition to comprehensive aspects of inelastic dynamic analyses, particularly in analysis and design of structures subjected to transient loads, they inherently suffer from convergence and computational cost problems. In this research, a strategy is proposed for design of steel moment resisting frames under far range blast loads. This strategy is inspired from performance based seismic design concepts, which is here developed to blast design. For this purpose, an algorithm is presented to calculate the capacity modification factors of frame members in order to simplify design of these structures subjected to blast loading. The present method provides a simplified design procedure in which the linear dynamic analysis is preformed, instead of the time-consuming nonlinear dynamic analysis. Nonlinear and linear analyses are accomplished in order to establish this design procedure, and consequently the final design procedure is proposed as a strategy requiring only linear structural analysis, while acceptance criteria of nonlinear analysis is implicitly satisfied.

Blast analysis of concrete arch structures for FRP retrofitting design

  • Nam, Jin-Won;Kim, Ho-Jin;Yi, Na-Hyun;Kim, In-Soon;Kim, Jang-Ho Jay;Choi, Hyung-Jin
    • Computers and Concrete
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    • v.6 no.4
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    • pp.305-318
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    • 2009
  • Fiber Reinforced Polymer (FRP) is widely used for retrofitting concrete structures for various purposes. Especially, for the retrofitting of concrete structures subjected to blast loads, FRP is proven to be a very effective retrofitting material. However, a systematic design procedure to implement FRP for concrete structure retrofitting against blast loads does not exist currently. In addition, in case of concrete structures with inarticulate geometrical boundary conditions such as arch structures, an effective analysis technique is needed to obtain reliable results based on minimal analytical assumptions. Therefore, in this study, a systematic and efficient blast analysis procedure for FRP retrofitting design of concrete arch structure is suggested. The procedure is composed of three sequential parts of preliminary analysis, breach and debris analysis, and retrofit-material analysis. Based on the suggested procedure, blast analyses are carried out by using explicit code, LS-DYNA. The study results are discussed in detail.

Design Optimization of Blast Resistant CFRP-steel Composite Structure Based on Reliability Analysis (신뢰성 해석에 의한 내폭 CFRP-steel 복합구조의 최적화 설계)

  • Kim, Jung Joong;Noh, Hyuk-Chun
    • Journal of the Korean Society for Advanced Composite Structures
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    • v.3 no.4
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    • pp.10-16
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    • 2012
  • This study presents the effectiveness of a composite structure at improving blast resistance. The proposed composite structure consists of carbon fiber reinforced polymer (CFRP) and steel layers. While CFRP layer is used for blast energy reflection due to its high strength, steel layer is used for blast energy absorption due to its high ductility. A dynamic model is used to simulate the elastoplastic behavior of the proposed composite structure subject to blast load. Considering the magnitude variations of a blast event, the probability of failure of each layer is evaluated using reliability analysis. By assigning design probability of failure of each layer in the composite structure, the thickness of layers is optimized. A case study for the design of CFRP-steel composite structure subjected to an uncertain blast event is also presented.

A Comparison of Blast Load in a Simplified Analytical Model of Rigid Column (강체 기둥의 단순 해석 모델에서의 폭발 하중 비교)

  • Park, Hoon
    • Explosives and Blasting
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    • v.37 no.3
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    • pp.1-12
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    • 2019
  • The analysis methods of blast analysis models are classified into direct analysis and indirect analysis, and the latter is divided into semi-empirical and numerical analysis methods. In order to evaluate the applicability of the ELS blast analysis program, which is a program for analyzing the semi-empirical models, this study selected a simplified analytical model and examined the blast load characteristics of free-air burst explosion and surface burst explosion by using AT-Blast, RC-Blast, and Kinney and Graham's empirical equations, which are the semi-empirical analysis programs. As a result of analyzing the explosion pressure for the scaled distance and the incidence angle for the simplified analytical model, an appropriate analysis can be performed when the range of the scaled distance in the free-air burst explosion analysis was 0.3~0.461 and when the range of the scaled distance in the surface burst explosion analysis was 0.378~0.581. In terms of the incidence angle, the results analyzed within $45^{\circ}$ were considered to be appropriate.

Behavior and simplified analysis of steel-concrete composite beams subjected to localized blast loading

  • Li, Guo-Qiang;Yang, Tao-Chun;Chen, Su-Wen
    • Structural Engineering and Mechanics
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    • v.32 no.2
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    • pp.337-350
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    • 2009
  • Finite element simulations are increasingly used in structural analysis and design, especially in cases where complex structural and loading conditions are involved. Due to considerable progresses in computer technology as well as nonlinear finite-element analysis techniques in past years, it has become possible to pursue an accurate analysis of the complex blast-induced structural effects by means of numerical simulations. This paper aims to develop a better understanding of the behavior of steel-concrete composite beams (SCCB) under localized blast loading through a numerical parametric study. A finite element model is set up to simulate the blast-resistant features of SCCB using the transient dynamic analysis software LS-DYNA. It is demonstrated that there are three dominant failure modes for SCCB subjected to localized blast loading. The effect of loading position on the behavior of SCCB is also investigated. Finally, a simplified model is proposed for assessing the overall response of SCCB subjected to localized blast loading.

Stress Analysis on the Profile of Blast Wall with Finite Element Method (유한요소법을 이용한 방폭벽 프로파일에 대한 응력해석)

  • Kim, Byung-Tak;Koh, Sung-Wi;Kim, Kwang-Heui
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.11 no.3
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    • pp.130-137
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    • 2012
  • Blast walls are integral structures at the typical offshore topside module to provide safety barriers for personnel and critical equipment against any blast loading and hydrocarbon explosions. The blast wall structures are usually configured with stainless steel. It can be referred as the good mechanical properties of the stainless steel against blast load, which features the characteristics of significant energy absorption and ductility. In this study, the proposed designs of corrugated panel are examined in order to determine the best design which satisfies the design criteria. The criteria on maximum deflection and stress are used to decide the best design. The effect of inclined angle of profile on deformation characteristics of blast wall is also performed. The numerical study was performed by using NX Nastran 7.5.

A new SDOF method of one-way reinforced concrete slab under non-uniform blast loading

  • Wang, Wei;Zhang, Duo;Lu, Fangyun;Liu, Ruichao
    • Structural Engineering and Mechanics
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    • v.46 no.5
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    • pp.595-613
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    • 2013
  • A new effective model for calculation of the equivalent uniform blast load for non-uniform blast load such as close-in explosion of a one-way square and rectangle reinforced concrete slab is proposed in this paper. The model is then validated using single degree of freedom (SDOF) system with the experiments and blast tests for square slabs and rectangle slabs. Test results showed that the model is accurate in predicting the damage level on the tested RC slabs under the given explosive charge weight and stand-off distance especially for close-in blast load. The results are also compared with those obtained by conventional SDOF analysis and finite element (FE) analysis using solid elements. It is shown that the new model is more accurate than the conventional SDOF analysis and is running faster than the FE analysis.