• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1995.04a
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• pp.66-66
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• 1995

Mutated forms of the ras oncogenes are associated with about 30% of human tumors. The ras genes encode 21KDa proteins, called p21 or Ras, that are associated with the plasma membrane. FPTase is a dimeric enzyme that catalyses the transfer of the farnesyl group from farnesyl pyrophosphate onto cysteine 186 at the C-terminus of the Ras protein. This is mandatory process for triggering ras oncogene toward tumor formation. Therefore, selective inhibitors of FPTase have the potential to be used as antitumorgenic agents.

• Proceedings of the Korean Nutrition Society Conference
• /
• 2001.05a
• /
• pp.199.2-199
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• 2001

• Proceedings of the PSK Conference
• /
• 2000.04a
• /
• pp.200.1-200.1
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• 2000

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1995.04a
• /
• pp.65-65
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• 1995

Cholesteryl Ester Transfer Protein(CETP), a hydrophobic glycoprotein with molecular mass 74KDa, is a lipid transfer protein found in plasma which mediates the transfer of cholesterol ester and triglyceride between high-density lipoprotein (HDL) and other lipoproteins, therefore, it might influence HDL levels. The lipoprotein profile associated with human CETP deficiency (that are two Japanese families, high HDL and low LDL) has low atherogenic potential, raising the possibility that CETP inhibitors can be used as antiatherosclerotic drugs.

• Proceedings of the PSK Conference
• /
• 2002.04a
• /
• pp.219.4-220
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• 2002

• Proceedings of the Korean Nutrition Society Conference
• /
• 2001.05a
• /
• pp.303.2-303
• /
• 2001

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.598-598
• /
• 2003

• Proceedings of the PSK Conference
• /
• 2000.04a
• /
• pp.200.2-200.2
• /
• 2000

• Proceedings of the PSK Conference
• /
• 2000.04a
• /
• pp.201.2-202
• /
• 2000

• Microbiology and Biotechnology Letters
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• v.25 no.6
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• pp.598-605
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• 1997

The characteristics of cell growth and cellulose production by Acetobcter xylinum BRC5 were studied in shaking flasks and jar fermentors. Of the substrates tested, the highest cellulose yield was obtained from the fructose medium. Some inductive cultivation was observed and then cellulose was produced with cell growth. When glucose alone or mixture of glucose and fructose was used as the carbon source, cellulose could be biosynthesized under the glucose limitation. Corn steep liquor (CSL), as a low-cost nitrogen source, was a good substitute for yeast extract. In a jar fermentor experiment, 4.14 g/l of disintegrated cellulose was obtained from 8% CSL- medium containing 0.5% glucose and 1.5% fructose.