• Journal of Species Research
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• 제9권1호
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• pp.46-55
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• 2020

Chrysosplenium grayanum Maxim. (Series Nepalensia), which had been known to be restricted to Japan, was newly discovered from Mt. Cheongtae in Yeonggwang-gun, Jeollanam-do, located in the southern part of the Korean Peninsula. Species identification was confirmed using morphological characteristics and DNA sequence data, while comparing with materials obtained from Japan and herbarium specimens. Chrysosplenium grayanum is clearly distinguished from the remaining taxa of the genus Chrysosplenium by having glabrous plant body, opposite leaves, cylindrical papillae with roundish head at the tip on the smooth seed surface, and four stamens. Molecular sequence data of the nuclear ribosomal ITS regions, chloroplast rbcL and matK genes strongly supported that this previously unknown Chrysosplenium species from Korea is C. grayanum. Taking the molecular and the morphological evidence into consideration, it is clear that newly discovered Chrysosplenium population in Korea is conspecific with the widely distributed C. grayanum in Japan. In this paper, we provide a description, illustration, and photo images of Chrysosplenium grayanum from Korea and also a key to the Chrysosplenium species in Korea.

• 대한의용생체공학회:의공학회지
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• 제22권4호
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• pp.369-375
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• 2001

The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 합동 추계학술대회 논문집 정보 및 제어부문
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• pp.450-453
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• 2002

In emergency telemedicine system based on wireless communication system with limited transmission capacity, it is necessary to transmit the biological data (ECG, BP, Respiration, $SpO_2$) of the patient continuously and reliably in real time. For this service, it is necessary to data compression and error control. In this study, we designed an protocol for error control in application layer and implemented it on the biological data transmission program for an emergency telemedicine system based on wireless data communication system.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회/대한산업공학회 2003년도 춘계공동학술대회
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• pp.1136-1141
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• 2003

Due to the lack of digitally usable standards, it has been known to be difficult to handle the biological data. For example, the name of genes and proteins changes over time or has several synonyms indicating different entities. To cope with these problems, several communities, including the Gene Ontology Consortium and PubGene are making their efforts to move science toward the semantic web vision. Although some progress has been made, its expressivity is not sufficient for full-fledged ontological modeling and reasoning. This paper suggests a methodology for representing and extracting biological knowledge by using Web Ontology Language (OWL) as an extension of Resource Description Framework Schema (RDFS). Some benefits of our approach are: (1) to ensure extended sharing of biological meta data on the Web, and (2) to enrich additional expressivity and the semantics of RDFS+OWL.

• 대한의용생체공학회:의공학회지
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• 제15권3호
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• pp.265-274
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• 1994

This paper proposes a method of noninvasive reflectance light to measure the blood fractional volume (Vb) and oxygen saturation ($SO_2$) of biological tissue. We chose the red light of 660nm and infrared light of 880nm. In Vivo reflectance data were obtained by the physiological changes front the surface of the skin over the calf in human subject. The reflected light intensity from different layers within a biological tissue was measured by specially designed reflectometer to apply photon path diffusion model. The collected data represent the changes of blood (ractional volume and oxygen saturation at each reflected light wavelengths. The data evaluation was assessed by examining the slopes of the plotted indices for the changes in oxygen saturation and blood (ractional volume. The results presented in this paper claim that light reflectance can separately discriminate the change of blood volume and that of oxygenation in muscle and also in skin.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 추계학술대회
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• pp.105-108
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• 1992

In this paper, we have implemented the telemedicine system which has a color image system and a biosignal processor. The inputted image is acquisited to 512 by 480 color image data. The col looted data is compressed to 1/5 of the original image data by using 1/5 and compression algorithm. A biological signals are inputted by 12 bit A/D converter into the system. In case of using 2400bps modem, a frame full color image data and biological information data needed 10 minutes in transmission.

• Genomics & Informatics
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• 제5권4호
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• pp.196-199
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• 2007

BOD is an FTP service management tool on the Internet. It was developed for biological researchers in South Korea. It enables easier and faster access of bioinformation without having to go through foreign FTP sites. BOD includes an automatic downloader with a management and email alert service from which the user can easily select and schedule any biological database. Once listed in BOD, the user can check and modify the download status and data from an additional email alert service.

• Journal of the Korean Data and Information Science Society
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• 제23권1호
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• pp.39-51
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• 2012

군집분석은 마이크로어레이 발현자료에서 유전자 혹은 표본들의 유사한 특성을 갖는 연관구조를 조사하는데 중요한 도구이다. 본 논문에서는 마이크로어레이 자료에서 계층적 군집방법, K-평균법, PAM (partitioning around medoids), SOM (self-organizing maps) 그리고 모형기반 군집방법 들의 성능을 3가지 군집 타당성 측도인 내적 측도, 안정적 측도 그리고 생물학적 측도를 가지고 비교분석하고자 한다. 모의실험을 통해 생성된 자료와 실제 SRBCT (small round blue cell tumor) 자료를 가지고 여러 가지 군집방법들의 성능을 비교하였으며 그 결과 모의실험 자료에서는 거의 모든 방법들이 3가지 군집측도에서 원래 자료와 일치하는 좋은 군집 결과를 나타내었고 SRBCT 자료에서는 모의실험 자료처럼 명확한 군집화 결과를 보여주지는 않으나 내적측도의 실루엣 너비 (Silhouette width) 관점에서는 PAM 방법, SOM, 모형기반 군집방법 그리고 생물학적 측도에서는 PAM 방법과 모형기반 군집방법이 모의실험 결과와 비슷한 결과를 얻었고 안정적 측도에서 모형기반 군집방법이 다른 방법들보다 좋은 군집결과를 보여주었다.

• 한국가스학회지
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• 제14권6호
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• pp.21-26
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• 2010

국내의 LNG 터미널은 일반적으로 대형화 되어있다. 그런데 이런 대형화된 터미널의 안전한 관리를 위해서는 전 시설에 대한 온도 관측이 필요하며 따라서 터미널 내 모든 시설에는 온도센서가 다수 존재한다. 하지만 터미널의 운영, 관리 및 안전사고 예방을 위해서 또 파악해야 하는 정보 중 하나가 유량인데 보통 부족한 경우가 많다. 그런데 배관의 온도 정보는 유량과 밀접한 관련을 맺고 있고 이를 통해 유량은 몇 가지 가정을 통해서 쉽게 추산할 수 있다. 이렇게 발생된 유량 데이터는 오차를 갖고 있을 수 있기 때문에 이를 정상상태 데이터 보정(steady state data reconciliation)을 활용하면 보다 신뢰성 있는 데이터를 얻을 수 있다. 본 논문에서는 이러한 LNG 터미널 데이터 보정 방법에 대해 설명하고 사례연구를 통해 얼마나 신뢰성 있는 데이터를 제공하는지에 대해서 기술하고자 한다.

• 환경생물
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• 제39권1호
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• pp.32-38
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• 2021

Cyanobium is a genus of picoprokaryotic cyanophytes, which includes species worldwide. The present study investigated the morphology, ultrastructure, and molecular phylogeny of the unrecorded genus Cyanobium Rippka & Cohen-Bazire 1983 and species Cyanobium gracile Rippka & Cohen-Bazire 1983. A C. gracile culture from a freshwater sample collected from the Adongji pond was established by single-cell isolation. Morphological data were analyzed using light and transmission electron microscopy. C. gracile lives as solitary cells without gelatinous envelopes and is ovate, oval, or shortly rod-shaped. Thylakoids are laid along the cell walls, with three thylakoid membranes parallel to each other. Nucleoplasm was observed in the center of the cell. Molecular phylogeny performed with data from 16S small subunit ribosomal DNA gene (SSU rDNA) sequences showed that the three strains of C. gracile, including the type strain (PCC6307) and a newly recorded strain (Adong101619), formed a distinct clade with a high supporting value (maximum-likelihood=100, pp=1.00). Based on morphology and molecular data, we report the newly recorded C. gracile in Korea.