• 대한의용생체공학회:의공학회지
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• 제22권6호
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• pp.497-502
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• 2001

혈액 속의 글루코즈 농도를 측정 시 타 성분이 미치는 영향을 분석하였다. 이를 위하여 헤모글로빈을 포함한 총 5 가지의 주요 성분을 이용하여 혈액 팬텀을 만들었으며 글루코즈의 배음대역을 포함하는 1500 ~ 1850nm의 흡수스펙트럼을 측정하여 농도 추정 모델을 세웠다. 농도 예측은 다변량통계분석 모델인 부분최소자승회귀분석을 이용하였다 다른 성분들이 글루코즈 측정에 있어 미치는 영향은 실험계획법을 적용한 인자 분석에 의하여 조사하였다. 트리 글라이세라이드는 영향을 미치지 않는 것으로 나타났으며. 알부민과 글로불린의 경우 적은 범위의 영향을 주는 것으로 나타났다 하지만 헤모글로빈의 영향은 큰 것으로 나타나 글루코즈 측정에 있어 헤모글로빈의 농도 보상이 필요한 것으로 판명되었다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 춘계학술대회
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• pp.240-242
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• 1996

In this paper, we proposed a method of a hearing aid suitable for the sensorineural hearing impaired. Generally as the sensorineural hearing impaired have narrow audible ranges between threshold and discomfortable level, the speech spectrum may easily go beyond their audible range. Therefore speech spectrum must be optimally amplified and compressed into the impaired's audible range. The level and frequency of input speech signal are varied continuously. So we have to make compensation input signal for frequency-gain loss of the impaired, specially in the frequency band which includes much information. The input sigaal is divided into short time block and spectrum within the block is calculated. The frequency-gain characteristic is determined using the calculated spectrum. The number of frequency band and the target gain which will be added input signal are estimated. The input signal within the block is processed by a single digital filter with the calculated frequency-gain characteristics. From the results of monosyllabic speech tests to evaluate the performance of the proposed algorithm, the scores of test were improved.

• 한국정밀공학회지
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• 제22권6호
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• pp.207-212
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• 2005

The purpose of this work is to develop the FES controller that can cope with the muscle fatigue which is one of the most important problems of current FES (Functional Electrical Stimulation). The feasibility of the proposed FES controller was evaluated by simulation. We used a fitness function to describe the effect of muscle fatigue and recovery process. The FES control system was developed based on the biological neuronal system. Specifically, we used PD (Proportional and Derivative) and GC (Gravity Compensation) control, which was described by the neuronal feedback structure. It was possible to control of multiple joints and muscles by using the phase-based PD and GC control method and the static optimization. As a result, the proposed FES control system could maintain the cycling motion in spite of the muscle fatigue. It is expected that the proposed FES controller will play an important role in the rehabilitation of SCI patient.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.178-186
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• 2007

This study is attempted to correct an error of electronic blood pressure meter with an optical sensor. In general, for a hospitalized patient, ECG, blood pressure, oxygen saturation, and respiration are basically measured to monitor the patient's condition. Opening of a blood vessel after it is occluded by pressurizing the cuff influences the blood flow of peripheral blood vessels as well as oscillation changes in the cuff. Blood vessels are occluded and peripheral blood flow disappears at cuff pressure above the examinee's blood pressure, while blood vessels are opened and peripheral blood flow appears again at cuff pressure under the examinee's blood pressure. Then Disappear-Appear Point Length(DAPL) of peripheral blood flow can be judged with the signal of peripheral blood flow, thus is available as a factor of error correction for electronic blood pressure meter. Also, systolic or diastolic blood pressure can be corrected with Appear-Point-Pressure(APP) of cuff pressure at a point where blood flow occurs and Appear-Maximum Pressure(AMP) of cuff pressure at the maximum amplitude point of peripheral blood flow after peripheral blood flow appears again. For verification, 27 examinees were selected, and their blood value was obtained through experimental procedure of 4 stages including induction of blood pressure change. The examinees were divided into two groups of experimental group and control group, regression analysis was conducted for experimental group, and correction of a blood pressure error was verified with optical signal by applying the regression equation calculated in experimental group to control group. As an experimental result, mean of the whole measurement errors was 5mmHg or more, which did not meet the standard fur blood pressure meter. As a result of correcting blood pressure measurements with data of DAPL, APP, and AMP as drawn out of PPG signal, systolic blood pressure, mean blood pressure, and diastolic blood pressure were $-0.6{\pm}4.4mmHg,\;-1.0{\pm}3.9mmHg$ and $-1.3{\pm}5.4mmHg$, respectively, indicating that mean of the whole measurement errors was greatly improved, and standard deviation was decreased.

• 의료법학
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• 제9권1호
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• pp.9-56
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• 2008

The medical practice does not always get a satisfatory result since the disease progress of patients are depended on patients' physical constitution and the doctors cannot control the outcomes about patients' physiological and biological reaction after the treatment. Moreover, the medical practice may bring wrong result fatalistically because of the unpredictablility of life. To demand for compensation of the damage to the doctors about these wrong result, the patient side holds the burden of proof that is between medical practice and demage, and there is damage from doctor's malpractice according to the accepted theory about the fundamental principle of distribution of the burden of proof. This falls not only under the liability of Tort Law, but also liability of Contract Law. However, the patient may be in difficult situation to prove the malpractice of doctors since he or she cannot recognize the facts because he or she was in unconscious while the medical practice was conducted, or they cannot judge precisely even though they recognize the facts. Nevertheless, the lawsuits against medical malpractice are the field that never achieves the equality of arms since the most of the evidence belong to the doctor's side. Hence, to maintain the principle of the equality of arms under the constitution, the theory leads to alleviate the burden of proof that patients hold. However, the doctors cannot be asked for the burden of proof that they conduct medical practice without errors. Because the doctors may experience difficulty to prove their innocence as the patients because of the unique characteristic that medical practices have. Therefore, the methods of the alleviation of the patient's burden of proof should have the equality of arms and the equal opportunity between the patients and the doctors with the evaluation of the justifiable interest from both the patients and the doctors. As the methods of the alleviation of the burden of proof, the alleviation of the demands and the degree of the burden of proof or resolutely the conversion of the burden may be considered. However, Recognizing the exception from general principle with converting the burden of proof is not proper in principle because the doctors may experience difficulty of the proof as the patients may have. If the difficulty of proof can be resolved by alleviating of the demands and the degree of the burden of proof, it is more desirable resolution rather than converting the burden of proof.

• 대한의용생체공학회:의공학회지
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• 제24권3호
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• pp.183-192
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• 2003

본 연구에서는 구현된 요분석 시스템으로 획득한 데이터를 보정하기 위하여 색 좌표 변환 기법을 제안하였다. 일반적으로 요분석 시스템은 요분석용 스트립의 정색반응을 검출하는 과정에서 여러 가지 비선형적인 특성 즉 광 모듈의 메커니즘, 하드웨어, 그리고 주변 환경에 의해 색 왜곡된 입·출력 특성을 지닌다 따라서 보다 높은 정확도와 재현성을 유지하기 위해 장비 특성화 기법을 도입하여 색 왜곡 현상을 보정하였다. 본 연구에서는 명암 보정, ,3차 스플라인 보간법에 의한 RGB 신호의 특성 곡선 추출, 기준색 고정 선형변환 기법을 사용하여 색 보정 과정을 수행하였다 색 보정을 위해 사용된 표준 장비는 1931년 CIE XYZ 색공간 특성을 지닌 좌표계로 설정하였으며, 동일한 칼라 샘플에 대해 요분석 시스템의 출력값과 표준 장비의 출력값이 일치되도록 하는 보정 행렬을 구하였다. 구현된 요분석 시스템을 색 보정한 후 기준 데이터와 비교한 결과 양호한 색상 정확도를 나타내었다 요분석용 스트립의 10 가지 항목에 대해 구현된 두 대의 요분석 시스템을 사용하여 실험한 결과 장비간 색차는 1.28이었다.

• 대한의용생체공학회:의공학회지
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• 제18권4호
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• pp.457-466
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• 1997

청력장애인이 전화상의 말에 대한 청취력을 향상시킬수 있는 보청기능이 있는 전화기를 개발하였다. 최근 청력장애인이 늘어나고 있으며 생산자로서의 사회참여 욕구 또한 늘어나고 있는데 이들은 자신의 핸디캡을 메워줄 보조기기를 강력히 원하고 있다. 보청기능 전화기는 음성으로써 외부 정보를 획득할 수 있는 기본적인 통신 보조기기의 한 형태이다. 본 연구팀은 청력장애인의 청력특성을 분석하고 전화기에 청력 보상법을 적용함으로써 보청기능이 있는 새로운 모델의 전화기를 개발하였고 3가지 분야의 시험(전기적 시험, 단어 인지도 시험, 사용자 시험)을 수행하여 이 전화기의 유용성을 평가하였다. 새 전화기는 4개의 대역통과필터를 가지고 있으며 각 밴드의 중심주파수는 전화라인의 특성과 심리음향학적인 특성을 고려하여 500, 1000, 2000, 3000 Hz로 설정하였다. 청력장애인은 전화기의 증폭특성을 자신의 청력에 맞도록 피팅(fitting)할 수 있다. 즉 자신의 손실된 청력을 잘 보상하도록 4개 필터밴드에 대한 볼륨조절을 개별적으로 조정할 수 있다. 전화기의 전체 이득은 250~32000Hz 대역내에서 20㏈ 이상이다. 시험결과 새 모델의 전화기가 기존의 전화기보다 청력장애인의 전화음성 이해도를 향상 시킨다고 증명되었다. 향후 측음 및 잡음 억제, 주파수 대역분리, 청력패턴 보상과 심리음향적 라우드니스(loudness)보상에 대한 연구가 필요하며 공학과 임상 분야에서의 청력장애인의 언어 이지특성 연구를 통하여 더욱 발전된 전화기가 개발될 수 있다고 판단된다.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2006년도 추계 종합학술대회 논문집
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• pp.856-859
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• 2006

병원용 근육통증 치료기는 저주파의 전기적, 물리적 힘을 이용하여 신체근육통증을 치료하는 장비이지만 특히 병원에서 환자를 대상으로 사용할 경우 장비를 사용하는 사람입장과 치료를 받게 되는 환자의 입장, 모두를 고려하는 것이 무엇보다 중요하다. 병원용 근육통증 치료기는 사각기둥 타입으로 Basic Design이 이루어졌으며 보다 신뢰성 있는 이미지 전달을 위해 Control Display부를 LCD(액정)로 채택하였다. Body 상단부(Control Panel)는 약50' 각도를 설정하여 빛의 반사에 의해 가독성이 떨어지는 피해를 최대한 줄일 수 있도록 하였다. Body 하단부에는 Caster를 설치하여 좌우 이동이 가능하도록 하여 사용상 편리성을 강조하였다. 본 연구는 기존 제품의 시장조사와 함께 설문조사를 실시하여 선호도를 조사한 결과를 반영하였으며 제품개발 관련 엔지니어들과 조율된 의견을 DESIGN방향에 적용하여 전형적인 제품디자인개발 프로세스를 거쳐 마무리되었다. 본 치료기 개발 연구는 문헌 조사를 바탕으로 FGI기법을 이용하여 직접 관련된 자료를 수집 분석하였다. 조사는 병원용 근육통증 치료기를 중심으로 조사하였으며 의사보다는 간호사가 설문에 응하였으며 구입선택 기준이나 가격부분은 사용자에 초점을 마추웠다. 직접적인 시장조사를 통한 본 연구는 향후 NEW MODEL개발에서 결과적으로 경쟁사 대비 단점으로 지적되는 사항을 보완 개선하는 측면으로 디자인 개발이 이루어졌으므로 향후 M/S확보 전략에 크게 이바지 할 것으로 기대가 된다.

• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.169-176
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• 2015

Implantable closed-loop epilepsy controllers require ideally both accurate epileptic seizure detection and low power consumption. On-chip oscillators can be used in implantable devices because they consume less power than other oscillators such as crystal oscillators. In this study, we investigated the tolerable error range of a lower power on-chip oscillator without losing the accuracy of seizure detection. We used 24 ictal and 14 interictal intracranial electroencephalographic segments recorded from epilepsy surgery patients. The performance variations with respect to oscillator frequency errors were estimated in terms of specificity, modified sensitivity, and detection timing difference of seizure onset using Generic Osorio Frei Algorithm. The frequency errors of on-chip oscillators were set at ${\pm}10%$ as the worst case. Our results showed that an oscillator error of ${\pm}10%$ affected both specificity and modified sensitivity by less than 3%. In addition, seizure onsets were detected with errors earlier or later than without errors and the average detection timing difference varied within less than 0.5 s range. The results suggest that on-chip oscillators could be useful for low-power implantable devices without error compensation circuitry requiring significant additional power. These findings could help the design of closed-loop systems with a seizure detector and automated stimulators for intractable epilepsy patients.

• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.676-683
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• 2007

A non-invasive respiratory gated radiotherapy system like those based on external anatomic motion gives better comfortableness to patients than invasive system on treatment. However, higher correlation between the external and internal anatomic motion is required to increase the effectiveness of non-invasive respiratory gated radiotherapy. Both of invasive and non-invasive methods need to track the internal anatomy with the higher precision and rapid response. Especially, the non-invasive method has more difficulty to track the target position successively because of using only image processing. So we developed the system to track the motion for a non-invasive respiratory gated system to accurately find the dynamic position of internal structures such as the diaphragm and tumor. The respiratory organ motion tracking apparatus consists of an image capture board, a fluoroscopy system and a processing computer. After the image board grabs the motion of internal anatomy through the fluoroscopy system, the computer acquires the organ motion tracking data by image processing without any additional physical markers. The patients breathe freely without any forced breath control and coaching, when this experiment was performed. The developed pattern-recognition software could extract the target motion signal in real-time from the acquired fluoroscopic images. The range of mean deviations between the real and acquired target positions was measured for some sample structures in an anatomical model phantom. The mean and max deviation between the real and acquired positions were less than 1mm and 2mm respectively with the standardized movement using a moving stage and an anatomical model phantom. Under the real human body, the mean and maximum distance of the peak to trough was measured 23.5mm and 55.1mm respectively for 13 patients' diaphragm motion. The acquired respiration profile showed that human expiration period was longer than the inspiration period. The above results could be applied to respiratory-gated radiotherapy.