• Title/Summary/Keyword: biological assessment

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Neuropsychological Evaluation of Visual Perception and Construction (시지각 및 구성능력의 신경심리학적 평가)

  • Lee, Chang Uk;Oh, Byung Hoon
    • Korean Journal of Biological Psychiatry
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    • v.4 no.1
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    • pp.24-28
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    • 1997
  • Visual perception is a complex process engaging many different aspects of brain functioning. Like other cognitive functions, the extensive cortical distribution and complexity of visual perceptional activites make them hihgly vulnerable to brain injury. Dectection and characterization of perceptual disorders require a careful clinical assessment as well as the application of selected neuropsychological tests. In this article we reviewed neuropsychological assessment of visual perception and constructional abilities. And the principal visuospatial disorders are discussed, the associated neuropsychiatric disorders are presented.

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Development and Evaluation of Criterion-Referenced Performance Assessment Items Based on the 7th National Science Curriculum -Subject Unit of Reproduction and Biological Accumulation- (제7차 교육과정에 근거한 준거지향적 수행평가 문항의 개발과 평가 -고등학교 과학 "생식"과 "생물 농축" 단원을 중심으로-)

  • Chung, Young-Lan;Park, Jin-Joo
    • Journal of The Korean Association For Science Education
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    • v.24 no.3
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    • pp.519-531
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    • 2004
  • In recent years, there has been an increased emphasis on performance assessment to evaluate students' abilities. Our nation has introduced a change in testing and assessment. Additional work on the efficacy, reliability, and comparability in order to develop the performance assessment item has been needed in the enforcement of the 7th National Science Curriculum. Also, criteria for professional and technical standards has been needed to be developed. The purpose of this study was to draw out various key concepts and to develop achievement standards, assessment standards and performance assessment items based on the 7th National Science Curriculum on the subject matter of reproduction(chapter 13) and biological accumulation(chapter 17). And also, this study examined the validity of completed performance assessment items based on classical test theory and polytomous item response theory. Twelve key concepts in chapter 13(reproduction) and four from chapter 17(biological accumulation) were abstracted. Twenty-six achievement standards in chapter 13(reproduction), and nine in chapter 17(biological accumulation) were developed. The achievement standards were determined in terms of knowledge(K), process skill(P) and attitude(A). Twenty-five assessment standards in chapter 13(reproduction) and nine in chapter 17(biological accumulation) were developed. Based on the developed achievement standards and assessment standards, twenty-two performance assessment items(seventeen open-ended questions, three essays, and two portfolios) with concrete grading criteria were developed. Eight open-ended items were applied to 240 10th graders to evaluate reliabilities of the test which consisted of four items per each chapter. The results would be suggested that the applied items were valid for performance assessment because item difficulties and item discriminations were proper. There was not much differences in item discrimination between interpretation from classical test theory and that from polytomous item response theory. However, there were some differences in item difficulties between the interpretations of two theories because the characteristics of examinees were reflected in classical test theory.

The Dynamic of Phytoplankton Communities and the Biological Water Quality Assessment at Three Artificial Weirs in Downstream of Namhan-river (남한강 3개 인공보의 식물플랑크톤 군집 변동과 생물학적 수질평가)

  • Shin, Hyun-Joo;Lee, Ok-Min
    • Journal of Korean Society on Water Environment
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    • v.30 no.6
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    • pp.612-621
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    • 2014
  • Physicochemical factors and the phytoplankton communities in the downstream area of Namhan-River were investigated from June 2012 to November 2013. We also assessed water quality using biological water quality indices. Total nitrogen was 2.4 mg/L, total phosphorus was 0.04 mg/L, and biological oxygen demand was 1.1 mg/L. This resulted in a level 2 (Ib, good) water quality rating. A total of 259 phytoplankton taxa were classified, consisting of 26 families, two subfamilies, 64 genera, 222 species, 32 varieties, and five formas. Bacillariophyceae dominated during a1l seasons and at all sites. The dominant species were Aulacoseira granulata, Cyclotella meneghiniana, C. stelligera, Melosira varians, Cocconeis placentula var. lineata, Nitzschia palea, N. amphibia, Cymbella minuta, and Achnanthes convergens. The diatom assemblage index for organic pollution values was level A-D, and TDI was level B-D. P-IBI at most sites was at the M (moderate) level, but TSI was at the E (eutrophic) level. Most indices dropped from upstream to downstream.

Perspectives provided by leopard and other cat genomes: how diet determined the evolutionary history of carnivores, omnivores, and herbivores

  • Kim, Soonok;Cho, Yun Sung;Bhak, Jong;O'Brian, Stephen J.;Yeo, Joo-Hong
    • BMB Reports
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    • v.50 no.1
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    • pp.3-4
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    • 2017
  • Recent advances in genome sequencing technologies have enabled humans to generate and investigate the genomes of wild species. This includes the big cat family, such as tigers, lions, and leopards. Adding the first high quality leopard genome, we have performed an in-depth comparative analysis to identify the genomic signatures in the evolution of felid to become the top predators on land. Our study focused on how the carnivore genomes, as compared to the omnivore or herbivore genomes, shared evolutionary adaptations in genes associated with nutrient metabolism, muscle strength, agility, and other traits responsible for hunting and meat digestion. We found genetic evidence that genomes represent what animals eat through modifying genes. Highly conserved genetically relevant regions were discovered in genomes at the family level. Also, the Felidae family genomes exhibited low levels of genetic diversity associated with decreased population sizes, presumably because of their strict diet, suggesting their vulnerability and critical conservation status. Our findings can be used for human health enhancement, since we share the same genes as cats with some variation. This is an example how wildlife genomes can be a critical resource for human evolution, providing key genetic marker information for disease treatment.

The Cytotoxic Constituents of Betula platyphylla and their Effects on Human Lung A549 Cancer Cells

  • Yang, Eun-Ju;An, Ju-Hee;Son, Youn Kyoung;Yeo, Joo-Hong;Song, Kyung-Sik
    • Natural Product Sciences
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    • v.24 no.4
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    • pp.219-224
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    • 2018
  • During the screening for cytotoxic compounds from plants grown in Korea, Betula platyphylla (BP) showed potent activity against the adenocarcinomic human alveolar basal epithelial A549 cell line. To identify the cytotoxic components from BP, the $CH_2Cl_2$ fraction with the most significant cytotoxic effect was applied to the column chromatographies. Seven compounds were isolated: lupeol (1), betulinic acid (2), (-)-rhododendrol (3), platyphyllenone (4), platyphyllone (5), (-)-centrolobol (6), and oleanolic acid (7). Among them, three diarylheptanoids (4 - 6) exhibited cytotoxicity toward A549 cells. Especially, $50{\mu}M$ of 4 reduced A549 cell viability to $18.93{\pm}0.82%$ compared to control ($100.00{\pm}21.48%$). Lactate dehydrogenase (LDH) leakage and intracellular reactive oxygen species (ROS) production were also induced by $50{\mu}M$ 4. This is the first report on the cytotoxic effect of BP-derived diarylheptanoids 4-6 against A549 cells. The compound 4 may be useful for the development of early hit compounds for non-small cell lung carcinoma, but the consideration about selectivity of 4 is required since 4 also showed the cytotoxicity in the human normal lung epithelial BEAS-2B cell line.

A Review of Stream Assessment Methodologies and Restoration: The Case of Virginia, USA

  • Bender, Shera M.;Ahn, Chang-Woo
    • Environmental Engineering Research
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    • v.16 no.2
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    • pp.69-79
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    • 2011
  • Rapid population growth and land use changes have severely degraded streams across the United States. In response, there has been a surge in the number of stream restoration projects, including stream restoration for mitigation purposes. Currently, most projects do not include evaluation and monitoring, which are critical in the success of stream restoration projects. The goal of this study is to review the current status of assessment methodologies and restoration approaches for streams in Virginia, with the aim of assisting the restoration community in making sound decisions. As part of the study, stream restoration projects data from a project in Fairfax County, Virginia was assessed. This review revealed that the stream assessment methodologies currently applied to restoration are visuallybased and do not include biological data collection and/or a method to incorporate watershed information. It was found from the case study that out of the twenty nine restoration projects that had occurred between 1995 and 2003 in Fairfax County, nineteen projects reported bank stabilization as a goal or the only goal, indicating an emphasis on a single physical component rather than on the overall ecological integrity of streams. It also turned out that only seven projects conducted any level of monitoring as part of the restoration, confirming the lack of evaluation and monitoring. However, Fairfax County has recently improved its stream restoration practices by developing and incorporating watershed management plans. This now provides one of the better cases that might be looked upon by stakeholders when planning future stream restoration projects.

Neural and Genetic Basis of Evasion, Approach and Predation

  • Park, Seahyung;Ryoo, Jia;Kim, Daesoo
    • Molecules and Cells
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    • v.45 no.2
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    • pp.93-97
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    • 2022
  • Evasion, approach and predation are examples of innate behaviour that are fundamental for the survival of animals. Uniting these behaviours is the assessment of threat, which is required to select between these options. Far from being comprehensive, we give a broad review over recent studies utilising optic techniques that have identified neural circuits and genetic identities underlying these behaviours.