• Title/Summary/Keyword: biological age

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Physical characteristics and age structure of Mongolian racerunner (Eremias argus; Larcertidae; Reptilia)

  • Kim, Ja-Kyoung;Song, Jae-Young;Lee, Jung-Hyun;Park, Dae-Sik
    • Journal of Ecology and Environment
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    • v.33 no.4
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    • pp.325-331
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    • 2010
  • In this study, we have evaluated the physical characteristics of neonate, female, and male Mongolian racerunners (Eremias argus) and determined the age structure of a population of the species in a field located in Taean-gun, Chungnam, South Korea. The physical parameters of females and males, including snout-vent length (SVL), head length, head width, and body mass were found to be significantly interrelated. Male Mongolian racerunners exhibited significantly longer heads than the females, but other physical parameters, such as SVL, head width, and body mass did not differ between the female and male specimens. In the study population, the females ranged in age from two to eleven years old and the males ranged between two to eight years of age. The number of females and males, when separated into different age classes, did not differ within each age class. Male Mongolian racerunners evidenced greater SVL growth coefficients than the females, but asymptotic SVL did not differ between the females and males.

Influencing Factors on Health-related Quality of Life According to Body Mass Index in Middle Age People (중년의 체질량지수에 따른 건강관련 삶의 질 영향요인)

  • Park, Min Jeong;Choi, So Eun
    • Journal of Korean Biological Nursing Science
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    • v.24 no.1
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    • pp.26-35
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    • 2022
  • Purpose: The purpose of this study was to investigate the influencing factors on health-related quality of life according to body mass index (BMI) in middle age people. Methods: Using the 2017 Korea Health Panel Data, a total of 4,711 subjects age 40-64 were selected and classified into four groups based on BMI levels (underweight, normal weight, overweight, obese). Influencing factors according to BMI in middle age people was analyzed using multiple regression. Results: Activity limited was the most influential factor for health-related quality of life in middle age people. Walking and stress were factors influencing health-related quality of life in all weight groups. In the overweight and obese group, suicidal impulse was a significant influencing factor on health-related quality of life. Conclusion: To improve the health-related quality of life of middle age people, effective walking and stress management for maintaining and managing health, as well as managing suicide risk in the overweight group and obese group are required.

Biological aspects and population dynamics of Indian mackerel (Rastrelliger kanagurta) in Barru, Makassar Strait, Indonesia

  • Andi Asni;Hasrun;Ihsan;Najamuddin
    • Fisheries and Aquatic Sciences
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    • v.27 no.6
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    • pp.392-409
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    • 2024
  • The present study aims to analyze the biological aspects and population dynamics of Indian mackerel in Barru waters. Data was collected in Barru for 11 months, from June 2022 to April 2023. The observed parameters of biological aspects included gonadal maturation stages (GMSs), size at first gonadal maturation, and length-weight relationship. Meanwhile, the aspects of population dynamics encompass age group, growth, mortality rate, and exploitation rate. Data analysis consisted of morphological selection of general maturation stages, Spearman-Kärber method in estimating gonadal first maturation size, Bhattacharya method in identifying age group, von Bertalanffy function through FISAT II to measure growth (L and K), Pauly Model to estimate mortality rate, Beverton & Holt Model to estimate Y/R, and virtual population analysis (VPA) analysis to estimate stock and fish yield. The results demonstrated that GMS I was observed to be dominant, followed by stages II and III. The initial gonadal maturation was estimated to be 17.98-19.28 cm (FL) for females and 17.98-19.27 cm (FL) for males. The length-weight relationship in male and female Indian mackerels indicated a positive allometric growth. The mode grouping analysis results from the fork length measurement revealed three age groups. It was also identified that the asymptotic length (L) = 29.5 cm (fork length), growth rate coefficient (K) = 0.46 per year, and theoretical age at zero length (t0) = -0.3576 per year. Total mortality (Z) = 2.67 per year, natural mortality (M) = 1.10 per year, fishing mortality (F) = 1.57 per year, and exploitation rate (E) = 0.59, the actual Y/R = 0.083 gram/recruitment, and optimal Y/R 0.03 gram/recruitment. Fishing mortality is higher than the natural mortality rate, and a high exploitation value (E > 0.5) also reflects over-exploitation. VPA analysis on fish yields and stock estimation reported a highly exploited rate between the 11.5 cm and 14.5 cm length classes and an exceeding current yield of 467.07 tons/year with a recommended yield of 233.53 tons/year to ensure population sustainability.

Four Cases of Late-Onset Schizophrenia (만발성 정신분열증 4례)

  • Park, Jong Deuk;Yoon, Doh Joon
    • Korean Journal of Biological Psychiatry
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    • v.2 no.2
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    • pp.295-300
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    • 1995
  • Late-onset schizophrenia(LOS) is a controversial entity. It has been thought that onset of schizophrenia is limited to early adulthood, but many European psychiatrists have reported on the occurrence of schizophrenia in late life. DSM-III restricted the diagnosis of schizophrenia to patients with onset of illness before age 45 years. But, DSM-III-R, DSM-IV, and ICD-10 recognize no upper limit to the age at onset of schizophrenia. Patients with LOS have more visual, tactile, and olfactory hallucinations. Patients with LOS have more persecutory delusions, premorbid schizoid personality traits, and less affective blunting. The course of illness was favorable in LOS. We present four cases of LOS. Their detailed clinical features are reported hear with brief review.

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Genomic approaches for the understanding of aging in model organisms

  • Park, Sang-Kyu
    • BMB Reports
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    • v.44 no.5
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    • pp.291-297
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    • 2011
  • Aging is one of the most complicated biological processes in all species. A number of different model organisms from yeast to monkeys have been studied to understand the aging process. Until recently, many different age-related genes and age-regulating cellular pathways, such as insulin/IGF-1-like signal, mitochondrial dysfunction, Sir2 pathway, have been identified through classical genetic studies. Parallel to genetic approaches, genome-wide approaches have provided valuable insights for the understanding of molecular mechanisms occurring during aging. Gene expression profiling analysis can measure the transcriptional alteration of multiple genes in a genome simultaneously and is widely used to elucidate the mechanisms of complex biological pathways. Here, current global gene expression profiling studies on normal aging and age-related genetic/environmental interventions in widely-used model organisms are briefly reviewed.

Bone age-based big data analysis of the biological maturity of adolescents (골연령 기반 유소년 생물학적 성숙도 빅데이터 분석)

  • Bae, Sang-joon;Kim, Dongho
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2022.01a
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    • pp.153-154
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    • 2022
  • 본 논문에서는 역연령으로 구분되었던 기존 생물학적 성숙도에 기반한 체력 지표가 아닌 골성숙도를 활용한 생물학적 성숙도에 기반하여 유소년의 신체에 맞는 체계적인 운동을 추천하는 기법을 제안한다. 이를 통해 유소년의 성장기에 개인화된 운동능력 발달을 성취하게 함으로써 국민 체력 증진에 기여하고 체육 공교육 활성화 및 유소년 피트니스 관리 산업 발전에 도움이 될 것으로 기대한다.

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A comparison of Multilayer Perceptron with Logistic Regression for the Risk Factor Analysis of Type 2 Diabetes Mellitus (제2형 당뇨병의 위험인자 분석을 위한 다층 퍼셉트론과 로지스틱 회귀 모델의 비교)

  • 서혜숙;최진욱;이홍규
    • Journal of Biomedical Engineering Research
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    • v.22 no.4
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    • pp.369-375
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    • 2001
  • The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

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Growth Rate, Sex Ratio, Age Structure and Mating Period of Korean Crayfish Cambaroides similis Natural population (한국산 가재 Cambaroides similis 자연 개체군의 성장률, 암수비율, 연령구조 및 교미시기)

  • Jung, Jae-Ho;Kim, Min-Seop;Ahn, Dong-Ha;Min, Gi-Sik
    • Journal of Aquaculture
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    • v.22 no.1
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    • pp.16-22
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    • 2009
  • Life history of Korean crayfishes Cambaroides similis (Koelbel) was studied 8 month from March to October, 2006 from the Gwanak mountain, Seoul, South Korea. By capture and recapture method, 551 crayfishes were collected analyzed during the experimental period. Based on the distribution pattern of body lengths, the local population putatively divided into four age groups. The sex ratio of male and female was almost equal. However, their growth rates varied by water temperature. Early juveniles seen during June became adult during August. The study findings suggest that late autumn is mating season.

Sirtuin signaling in cellular senescence and aging

  • Lee, Shin-Hae;Lee, Ji-Hyeon;Lee, Hye-Yeon;Min, Kyung-Jin
    • BMB Reports
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    • v.52 no.1
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    • pp.24-34
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    • 2019
  • Sirtuin is an essential factor that delays cellular senescence and extends the organismal lifespan through the regulation of diverse cellular processes. Suppression of cellular senescence by Sirtuin is mainly mediated through delaying the age-related telomere attrition, sustaining genome integrity and promotion of DNA damage repair. In addition, Sirtuin modulates the organismal lifespan by interacting with several lifespan regulating signaling pathways including insulin/IGF-1 signaling pathway, AMP-activated protein kinase, and forkhead box O. Although still controversial, it is suggested that the prolongevity effect of Sirtuin is dependent with the level of and with the tissue expression of Sirtuin. Since Sirtuin is also believed to mediate the prolongevity effect of calorie restriction, activators of Sirtuin have attracted the attention of researchers to develop therapeutics for age-related diseases. Resveratrol, a phytochemical rich in the skin of red grapes and wine, has been actively investigated to activate Sirtuin activity with consequent beneficial effects on aging. This article reviews the evidences and controversies regarding the roles of Sirtuin on cellular senescence and lifespan extension, and summarizes the activators of Sirtuin including Sirtuin-activating compounds and compounds that increase the cellular level of nicotinamide dinucleotide.