• Title/Summary/Keyword: biochip

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The Scattering Beam Measurement of the RBC and the Fabrication of the Micro Cell Biochip (적혈구의 산란빔 측정과 마이크로 세포 분석 바이오칩 제작)

  • Byun, In Soo;Kwon, Ki Jin;Lee, Joon Ha
    • Progress in Medical Physics
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    • v.25 no.2
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    • pp.116-121
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    • 2014

  • Next future, The bio technology will be a rapidly developing. This paper is the scattering beam measurement of the red blood cell (RBC) and the fabrication of the micro cell biochip using the bio micro electro mechanical system (Bio-MEMS) process technology. The Major process method of Bio-MEMS technology was used the buffered oxide etchant (BOE), electro chemical discharge (ECD) and ultraviolet sensitive adhesives (UVSA). All experiments were the 10 times according to the process conditions. The experiment and research are required the ultraviolet expose, the micro fluid current, the cell control and the measurement of the output voltage Vpp (peak to peak) waveform by scattering angles. The transmitting and receiving of the laser beam was used the single mode optical fiber. The principles of the optical properties are as follows. The red blood cells were injected into the micro channel. The single mode optical fiber was inserting in the guide channel. The He-Ne laser beam was focusing in the single mode optical fiber. The transmission He-Ne laser beam is irradiating to the red blood cells. The manufactured guide channel consists of the four inputs and the four outputs. The red blood cell was allowed with the cylinder pump. The output voltage Vpp waveform of the scattering beam was measured with a photo detector. The receiving angle of the output optical fiber is $0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $15^{\circ}$. The magnitude of the output voltage Vpp waveform was measured in the decrease according to increase of the reception angles. The difference of the output voltage Vpp waveform is due differences of the light transmittance of the red blood cells.

  • https://doi.org/10.14316/pmp.2014.25.2.116 인용 PDF KSCI

바이오 센서 및 랩온어칩

  • 박유근
    • The Magazine of the IEIE
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    • v.31 no.1
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    • pp.58-72
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    • 2004

  • Smart sensors and biochip technologies have received a great deal of attention in recent years not only because of the enormous potential markets in the healthcare expenditures but more importantly because of its great impact on the quality of human life in the future. Collaborative research among BT (Bio Technologies), IT (Information Technologies) and NT (Nano Technologies) will bring us a new paradigm of the healthcare services. Examples include disease prediction based on the genetic tests, personal medicines, point-of-care analysis, rapid and sensitive infectious disease diagnostics, environmental monitoring for chemical or biological warfares, intelligent drug delivery systems etc. In this report, recent accomplishment in the research area on biosensors, DNA chips, Protein Chips and Lab-on-a-chips are reviewed.

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Modeling of cochlear biomechanics using Hspice (Hspice를 사용한 달팽이관 생역학의 모델링)

  • Jarng SoonSuck
    • Proceedings of the Acoustical Society of Korea Conference
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    • autumn
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    • pp.171-174
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    • 2004

  • 본 논문은 Hspice 를 사용한 달팽이관 생역학의 능동적이며 선형적인 1 차 그리고 2 차원 모델링을 보여준다. Hspice 모델링의 장점은 달팽이관 생역학을 아날로그 IC 칩으로 구현할 수 있다는 점이다. 즉 Biochip 으로 설계하는데 활용된다. 본 논문은 달팽이관 생역학을 어떻게 전기회로 모델화한 뒤, 다시 어떻게 Hspice 코드로 표현하는 가를 보여준다. 달팽이관 회로가 Hspice 코드 실행을 위해 변형되어야만 하는 과정을 상세히 보여준다. 1 차원의 결과와 2 차원의 결과를 비교하고 있다.

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Proteomics and Microarrays in Cancer Research

  • Kondabagil, Kiran-Rojanna;Kwon, Byoung-Se
    • Journal of Microbiology and Biotechnology
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    • v.11 no.6
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    • pp.907-914
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    • 2001

  • A whole genome analysis for monitoring specific changes in gene expression, using microarrays or proteome profiling of the same, are the two tools that have already revolutionized current approaches for studying disease. These methods are particularly important in cancer research as there are many overexpressed genes, and their products remain uncharacterized. This article presents a general overview of these technologies and their applications for studying cancer.

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