• Title/Summary/Keyword: bio-systems

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BioSubroutine: an Open Web Server for Bioinformatics Algorithms and Subroutines

  • Lee, Joowon;Kim, Hana;Lee, Wonhye;Chung, Dongil;Bhak, Jong
    • Genomics & Informatics
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    • v.3 no.1
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    • pp.35-38
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    • 2005
  • We present BioSubroutine, an open depository server that automatically categorizes various subroutines frequently used in bioinformatics research. We processed a large bioinformatics subroutine library called Bio.pl that was the first Bioperl subroutine library built in 1995. Over 1000 subroutines were processed automatically and an HTML interface has been created. BioSubroutine can accept new subroutines and algorithms from any such subroutine library, as well as provide interactive user forms. The subroutines are stored in an SQL database for quick searching and accessing. BioSubroutine is an open access project under the BioLicense license scheme.

Interpretation of Association Networks among Protein Sequence Motifs

  • Kam, Hye J.;Lee, Junehawk;Lee, Doheon;Lee, Kwang H.
    • Genomics & Informatics
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    • v.1 no.2
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    • pp.75-79
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    • 2003
  • Every protein can be characterized by either a distinct motif or a combination of motifs. Nevertheless, little is known about the relationships among (more than two) the motifs. Some of the proteins in the world are share motifs for evolutional or other biological benefits - they can save energy, time and resource for controlling and managing a variety of proteins. In some cases of motifs, the tendency is quite common and they can act the 'hub' motif of a network of the motif associations. The hubs are structurally and functionally important in themselves and also important in disease-related mutations. They will be highly resistant mutation to conserve their functions. But, in case of the a rare mutation, mutations on the position of hub can more easily cause fatal diseases.

Microfluidic Device for Bio Analytical Systems

  • Junhong Min;Kim, Joon-Ho;Kim, Sanghyo
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.2
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    • pp.100-106
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    • 2004
  • Micro-fluidics is one of the major technologies used in developing micro-total analytical systems (${\mu}$-TAS), also known as “lab-on-a-chip”. With this technology, the analytical capabilities of room-size laboratories can be put on one small chip. In this paper, we will briefly introduce materials that can be used in micro-fluidic systems and a few modules (mixer, chamber, and sample prep. modules) for lab-on-a-chip to analyze biological samples. This is because a variety of fields have to be combined with micro-fluidic technologies in order to realize lab-on-a-chip.