• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.55-69
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• 2007

The purpose of this study was to perform a clinical test using ez NANOsence II RGP contact lenses for the effects of visual acuity and cornea on subjects with abnormal refraction status. One hundred twenty one adults (twenty nine males, ninety two females, range = 17 to 43, mean = 22.86) were recorded. The subject's history including, the symptoms from previous lens wear, were studied. The subjects were observed, both pre and post lens wear, for any symptoms and signs of change of the eye. The Visual acuity and the binocular status were tested at the far distance using the contact lens. The refraction test was performed on the naked eye using the objective method (Topcon KR-8100, Japan). The Stereopsis test was performed at the near distance after contact lens wear by the Titmus fly (Stereo Optical Co., U.S.A) and TNO (TECH, The netherlands). The contrast sensitivity diagnosis was performed at 1m distance after contact lens wear by the contrast sensitivity chart (pelli-Robertson, USA). The corneal topography was analyzed on the naked eye after lens wear by ORB scan (Bausch Lomb, U.S.A.). The ultra structure of surface on the contact lens was observed using SEM (JMS-5800, Japan). The chemical component's of the contact lens was analyzed by EDS program. The results of this study were as follows: 1. The longer of contact lens wear period, The subjects have acquired the most improved visual function. 2. Subjects had experienced few side effects wearing the contact lenses. 3. The lenses were easy to use by the subjects. 4. The longer of contact lens wear period, the power of cornea had more decrease. but the base curve of cornea had more increase and corneal astigmatism was decrease (p<0.01). Also, the thickness of corneal center was few decrease. 5. Longer periods of using the contact lens showed stereopsis and contrast sensitivity at more normal values. 6 The corneal topographical after lens wear showed most subjects with similar morphology for different wear periods. 7. The surface ultrastructure of the new and used contact lens was the similar fine shape. 8. The chemical component's of in the new and used contact appeared to have similar results. In conclusion, this study showed that the surface ultrastructure and chemical component's of the new and used contact lens are similar. In addition, the subjects had improved the quality of vision and few experienced any side effects during long periods of contact lens wear. Also they have decrease of corneal astigmatism during the long period of lens wear. Our test has showed that the chemical composition and fine structure of contact lens have related to the visual function on contact lens wearer. In this paper, we suggested that ez NANOsence II RGP contact lenses had a moderate effect for correcting vision of abnormal refraction eye.

• Journal of The Korean Ophthalmological Society
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• v.58 no.4
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• pp.380-386
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• 2017

Purpose: To compare the clinical characteristics and prognosis of Fuchs dystrophy patients according to COL8A2 gene mutation status. Methods: Eighty-one patients (162 eyes) initially diagnosed with Fuchs dystrophy from 1996 to 2015 were divided into two groups according to COL8A2 gene mutation status. Retrospective analysis was performed comparing gender, age at diagnosis, presence of family history, diabetes mellitus, symptoms of blurred vision in the morning, changes in central corneal thickness and endothelial cell density with time, need for corneal transplantation, and pre-operative corneal status in the two groups. Results: Of the 81 patients, 12 were shown to harbor a COL8A2 gene mutation. Individuals with mutation were significantly associated with presence of family history, diabetes mellitus, and blurred vision in the morning (p = 0.021, p = 0.024, p = 0.044, respectively). They also had significantly thicker central cornea and lower endothelial cell density at the time of diagnosis (p = 0.020, p = 0.005, respectively). The differences in central corneal thickness and endothelial cell density between the two eyes in one patient were significantly smaller in patients with gene mutation (p = 0.043, p = 0.022, respectively). Over a 5-year follow-up period, 60.0% of eyes in patients with gene mutation and 19.2% of eyes in patients without gene mutation underwent corneal transplantation, a significant difference between the two groups (p = 0.014). Conclusions: By testing for COL8A2 gene mutation, early binocular disease progression and the possible need for corneal transplantation in the future can be predicted among patients diagnosed with Fuchs dystrophy.

• Journal of Korean Ophthalmic Optics Society
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• v.11 no.3
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• pp.231-240
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• 2006

This study conducts a questionnaire survey of 492 middle school students in Jeju islands about the rate of using glasses/contact lens, the place and time of visual acuity test, the period of changing the glasses, the purchase price, the mason to change the glasses, the interrelationship between wearing spectacles and residential district, etc. The results are as follows: 1. 45.33% of the object of investigation use the glasses or contact lens to correct their visual acuity. Among them, the student who wears only glasses is 93.27%, the student who wears glasses and contact lens together is 5.83%, the student who wears only contact lens is 0.90%. 2. As for the period of changing his(her) glasses, below 6 month is 20.18%, from 6 month to one year is 52.02%, from one year to two years is 20.18% and more than two years is 7.62%. 3. As for the purchase price to change his(her) glasses, below 30,000won is 13.45%, from 30,000won to 50,000won is 43.50%, from 50,000won to 70,000won is 23.77%, from 70,000won to 100,000won is 15.25% and more than 100,000won is 4.03%. 4. As for the reason of changing his(her) glasses, cause of change of visual acuity is 55.16%, by broken frame and lens is 27.35%, as want to just change his(her) spectacles is 14.80% and as the others is 2.69%. 5. As for the relative importance in purchasing glasses, the student who thinks more frame is 16.59%, the student who thinks more lens is 67% and the student who thinks both frame and lens is 58.74%. 6. As for the frist time of visual acuity test, 1 grade of elementary school is 37.2%, 3 grade of elementary school is 12.56%, 4 grade of elementary school is 11.66% and 6 grade of elementary school is 11.66%. 7. As for the place of visual acuity test to determine the Dptr. of glasses which wear now, opitican's shop is 57.85% and ophthalmic clinic is 42.15%. 8. As for the frist time of wearing the glasses or contact lens for correct his(her) visual acuity, the most of answer(21.97%) is at 6 grade of elementary school. 9. As for the reason why does not wear the glasses or contact lens though his(her) naked binocular vision is below 0.8, as does not feel any difficulty in daily life is 62.5%, as know that the more wear, the more decrease his(her) visual acuity is 15.65%, by economical circumstance is 6.24% and as not good externally is 15.63%, respectively.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.71-75
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• 2007

This research was conducted from 1 March 2005 to 28 February 2007. We collected data from optician stores around Kwang-Ju city, 208 people aged 40 to 80 years using the cross cylinder method to find out age and gender dependence of near addition. 1. Age dependence of Refractive error shows 5% of emmetropia 34% of myopia and 43% of hyperopia. These results reveal that rate of hyperopia is higher than emmetropia and myopia. Mixed Astigmatism rate was 18%. 2. Near addition required to correct Presbyopia is analyzed as functions of gender and ages. In case of man: 40-44 (+0.75D), 45-49(+1.25D), 50-54(+1.41D), 55-59(+1.92D), 60-64(+2.35D), 65-69(+1.97D), 70(+3.12D), In case of woman: 40-44 (+1.08D), 45-49 (+1.38D), 50-54 (+1.67D), 55-59(+2.05D), 60-64 (+2.50D), 65-69 (+2.57D), $70{\leq}(+3.18D)$. Result shows it's Adding power higher than man. 3. Age dependence of Axis of Astigmatism. In case of horizontal astigmatism 61.2%, vertical 2.8% and rest else for 36%. Setting point from Binocular vision tells that average adding power of 40-44 (+0.75D) or (+1.00D), 45-49 (+1.25D) or (+1.50D), 50-54 (+1.50D), 55-59 (+2.00D), 60-64 (+2.50D), 65-69 (+2.50D) or (+2.75D), over $70{\leq}(+3.00D)$ or (+3.25D) of average adding power.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.1
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• pp.25-30
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• 2010

Purpose: This study was conducted to estimate the changes of corrected diopter and corrected visual acuity with the change in vertex distance. Also we aimed to provide basic data for refraction test. Methods: Using the trial lens, we measured the corrected diopter and corrected visual acuity after performing binocular balance test. We measured the changes of corrected diopter and corrected visual acuity in change of vertex distance. We analyzed statistical significance and relations between vertex distance and corrected diopter and corrected visual acuity. Results: There was no difference in corrected diopter with the change of vertex distance within -1.00D, but the corrected diopter increased with it over - 1.25D. In particular, the change of diopter was largest when the vertex distance increased 15 mm. At over 11.00D, there was large changes of diopter with the changes of vertex distance at 5 mm, 10 mm and 15 mm. On correlation analysis between the vertex distance and the corrected diopter, there was strong correlation (r=0.999 at 5 mm increase of vertex distance, r=0.982 at 10 mm increase and r=0.957 at 15 mm increase) and also there was significant (p<0.01). At the change of visual acuity in increased of vertex distance, the range of a decrease in visual acuity was large when the changes of vertex distance was largest. On correlation analysis between the vertex distance and the corrected visual acuity, there was strong correlation (r=0.969 at 5 mm increase of vertex distance, r=0.985 at 10 mm increase and r=0.994 at 15 mm increase) and also there was significant (p<0.01). Conclusions: The vertex distance was very important at the refraction test and at wearing spectacle. On correlation analysis between the vertex distance and the corrected diopter, and the corrected visual acuity, there was strong correlation and statistically significant. Therefore, the vertex distance should be kept at the refraction using trial lens, and the best fitting was made not to slipping forward, and so we suggested regular refitting of spectacle and the managing method of spectacle were educated to the spectacle wearers.