• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.3
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• pp.504-511
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• 2010

Diabetes is a disease that contains a high concentration of glucose in blood and due to defects in either insulin secretion or insulin action. Although the distinctive causes and factors of diabetes have not been clarified, the genetic factors are suggested as a main susceptibility until now. SNP (Single Nucleotide Polymorphism), as the most common genetic variation, has an influence on personal susceptibility for diseases. A nonsynonymous SNP, which changes the amino acid of the protein and its function, is especially important. Therefore, this study hypothesized that there are associations between specific SNPs of the targeted genes. Transcription factor 7-like 2 (TCF7L2) and fat mass and obesity associated (FTO) genes were selected as target genes from the results of genome-wide association and other related research studies. Second, four nonsynonymous SNPs (three in TCF7L2 and one in FTO gene) were selected as target SNPs by using public database of NCBI (National Center for Biotechnology Information). The recruited personnel was classified into three subgroups of diabetes, impaired fasting glucose (IFG) and normal groups. The individual genotypes of each group were analyzed by resequencing. None of genetic variations at four targeted SNP sites was revealed in all samples of this study. However, this study found two new SNPs that were not reported in TCF7L2 gene. One is synonymous SNP, which is heterozygous of C/T and no amino acid change of asparagine/asparagines, was located at c1641 and found in one normal person. Another is nonsynonymous SNP, which is heterozygous of G/A, was located at c1501 and found in two samples. This new discovered nonsynonymous SNP induce the amino acid change from alanine to threonine. Moreover, this new nonsynonymous SNP was found among two persons, one of whom was a diabetes patient and the other one was a person at boundary between IFG and normal, suggesting that this variant might be associated with IFG or diabetes. Even if there is a limitation of sample number for statistical power, this study has an importance due to the discovery of new SNPs. In the future study, a large sample number of diabetes cohort will be needed to investigate the frequency and association with new discovered SNP.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.1
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• pp.113-122
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• 2002

Purpose: The purpose of this study was to identify characteristics of serum ferrum, TIBC and ferritin's circadian rhythm in normal adults and to prepare a standard to determine the examination material extraction time. Method: Nine women and ten men made up the convenience sample for this study they were from the staff of D university hospital and students in D medical School located in K city who met the qualifications for inclusion in the sample. The value of serum ferrum, TIBC and circadian rhythm were calculated as follows : First. each variable's amplitude. the acrophase and average were measured for a 24 hour cycle using the cosinor method, and then each person's rhythm was analyzed. Results: There were significant serum iron circadian rhythm for both men and women (p<.05). For the men, mesor was $105.91{\mu}g/dl$. amplitude was $29.52{\mu}g/dl$, and the acrophase was 9.76 hour. For the women, mesor was $108.17{\mu}g/dl$, amplitude was $28.09{\mu}g/dl$, and the acrophase was 11.42 hour The rhythm change of TIBC was only significant for the women (p<.05), mesor was 383.39mg/dl, amplitude was 60.29mg/dl. and the acrophase was 14.93hour. As for the circadian rhythm of the ferritin, there are no diurnal variation in either sex, men were between 134.0ng/ml and 137.4ng/ml, and women, between 29.1ng/ml and 30.1ng/ml. Conclusion: To help diagnose the boundary line between normal or deficiency in iron, measurement should be carried out at a fixed time in the morning and evening, or a more proper time would be in the afternoon at the time when the width of amplitude is the least.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.45 no.2
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• pp.173-179
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• 2012

The common squid $Todarodes$ $pacificus$ is a dominant species in Korean waters, where it is captured preponderantly by the angling fishery. The spawning and nursery grounds of $T.$ $pacificus$ extend from the southern East Sea to the northern East China Sea. Consequently, the environmental conditions in this area during the spawning and nursery seasons might affect the abundance of $T.$ $pacificus$. This study, analyzed the relationship between the distribution of zooplankton and the abundance of $T.$ $pacificus$ and variation in the squid angling fishing grounds in Korean waters. There was a positive relationship between the fluctuations in zooplankton and the catch per unit effort (CPUE; $kg{\cdot}day^{-1}{\cdot}person^{-1}$) of the angling fishery in the East Sea of Korea. The main fishing season is from July to December and the CPUE was closely related to the zooplankton biomass in April in the East Sea. Recently, the center of the squid jigging ground has moved drastically from the area around Ulleung Island to the northern East Sea. We postulate that the fishing grounds of the squid angling fishery will move farther north with climate change.

• Management & Information Systems Review
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• v.10
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• pp.1-31
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• 2002

As the modern society is called the narcissistic society, the narcissism is widespread in the personality of individuals and the society at large. In consideration of this side, this study explored for several characteristics of the narcissistic personality and the job stress, and explored for the relationships between the two things theoretically. The narcissism is an attempt to repair self-esteem weakened by the splitting anxiety, the lack and the pathological fusion of self-structure. The job stress is a factor that a characteristic of the job influenced on the behavioral and affective response of the person on the job directly or indirectly. This study selected organizational justices, organizational constraints, role conflict, role ambiguity, role overload, organizational climate, interpersonal relations and career development as factors of the job stress. This study viewed that the stress is made from an interaction between environmental stimulus and personal particular reaction by defining the stress as an interaction model of stimulus-response and personal reaction is caused by psychological adjustment process, personal differences. On this occasion, this study discussed that the narcissistic personality is easy to get stress and weak in the job stress with regarding the personality as a mediation variation of psychological process. As a result, the narcissists estimated themselves positively and their self-esteem is high, but they excessively showed a self biased cognitive and affective response about the negative feedback to protect themselves. Moreover, this positive estimate on themselves and high self-esteem was vulnerable and weak in the self threat. In this view, the narcissistic personality is easy to get more job stress such as organizational justices, organizational constraints, role conflict, role ambiguity, role overload, organizational climate, interpersonal relations and career development.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.12 no.1
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• pp.49-56
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• 1982

The purpose of this study was to observe the anatomic variation of condylar head and the positional relationship between condylar head and other anatomic structures of head by means of cephalometry using the submentovertex cephalogram from each person in centric occlusion for producing a good quality of temporomandibular joint radiograph. The 100 submentovertex cephalograms of 100 Korean adults consisted of 50 females ranged from 20 to 24 years age and 50 males ranged from 22 to 30 years age, were studied and analyzed statistically. The results were as follows; 1. The mean of the horizontal angulation of condylar head to the transmeatal line (EE-LA) was 18.5° (S.D. 7.9°), and all measurements that indicate the horizontal angulation of condylar head showed considerable differences among individuals. 2. In the comparison of male vs. female in the measurements, statistically significant differences were found in the majority of measurement items, and with exception of R-LA and LA-LA, the rest of these measurements were larger in male than in female. 3. In the comparison of left vs. right in the measurements, statistically significant differences were found in the majority of measurement items, and with exception of PC-CC, the rest of these measurements were larger in right than in left. As above, because the majority of measurements that involve the horizontal angulation of condylar head varied among individuals, between male and female, and between left and right, the condition of various temporomandibular joint radiography should be determined by means of cephalometry using the submentovertex cephalogram for producing the accurate radiographic image of temporomandibular joint.

• Journal of Biomedical Engineering Research
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• v.31 no.5
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• pp.401-406
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• 2010

Recently, many implantable medical devices have been developed and manufactured in many countries. In these devices, generally, energy is supplied by a transcutaneous method to avoid the skin penetration due to the power wires. As the most transcutaneous power transmission methods, the electromagnetic coupling between two coils and resonance at a specific frequency has been used widely. However, in case of a transcutaneous power transmitter with a fixed switching frequency to drive an electromagnetic coil, inefficient power transmission and thermal damage by the undesirable current variation may occur, because the electromagnetic coupling state between a primary coil and a secondary coil is very sensitive to skin thickness of each applied position and by person. In order to overcome these defects, a transcutaneous power transmitter of which operating frequency can be automatically tracked into the resonance frequency at each environment has been designed and implemented. Through the results of experiments for different coil surroundings, we have been demonstrated that the implemented transcutaneous power transmitter can track automatically into a varied resonance frequency according to arbitrary skin thickness change.

• Korean Journal of Child Studies
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• v.2
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• pp.55-66
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• 1981

Research on children should be perferably made in reference with the past thinking if it is to be affirmed by the present and to predict the future. In this respect, Buddhism, which is one of the major original thinkings in the Orient as well as the most influential religion upon Koreans daily lives and attitudes, deserves to be researched in the light of education of children. In this thesis, I have made a trial to delve into the original Buddhistic scriptures to find out Buddha's outlook on home children and arrived at the following conclusions: 1. Concerning human development stages, Buddha regarded the starting point of human life from fertilization instead of birth, even at that ancient time, and the fetal life was devided into 4, 5, or 8 stages. 2. In spite of the numerous scriptures by Buddha, very little is written about children, and even these teaching did not regard the child as an independent entity. In addition, since Buddha was a person of superior enlightenment, he did not regard the age of human beings as of great importance. 3. On the relationship between parents and children, Buddha warned the extra ordinary attachment of parents toward children, because such attachment would be an obstacle in the search of truth. This idea was originated from his thought that the relationship between parents and children was not a single fixed one but of unlimited variation through numerous life times of reincarnation. This idea gives some illumination upon the problems of today's education where parent's exclusive attachment to their children and over-protection are hindrance for successful education. 4. Buddha put emphasis on parents' social duty, by which he meant that parents should care and accept not only their biological children but all children and all living things as if they were their own children. 5. Regardeding the children's role to their parents, Buddha taught that children should respect and support their parents under any condition. Buddha also emphasized that true filial piety was to help parents to improve their religious status by helping them attain the truth, morality, and wisdom. It is my intention to investigate Buddha's View tin children of entering pristhood.

• Journal of the Korean Society of Food Science and Nutrition
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• v.19 no.3
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• pp.248-262
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• 1990

General purpose of the study was to understend nutritional status of the Korean farmers and thus provide rural nutrition intervention programs with more useful in formation and data. The data for the study was collected two times from the 603 sample farm households in 1982 and 1987. The main results of the study were as follows ; 1) Food intake of the Korean farmers was highly dependent upon vegetable foods especially on cereals and gains. However the unbalanced food intake pattern was gradually improved as consumption of vegetable foods was decreased from 992.8 grams per person per day in 1982 to 946.4g in 1987 and that of animal foods increased from 54.2g to 91.4g . 2) In mean value analysis on nutrient intake of the farmeres intakes of energy and protein were nearly reached to Recommended Dietary Allowances(RDA) level; intakes of calcium vitamin A and riboflavin were quite deficient whereas iron thiamin niacin and ascorbic acid were well over. From 1982 to 1987 intakes of all nutrients except energy were increased. 3) In distribution analysis on nutrient intake coefficient of variation(CV) of all nutrients except iron was increased. skewness(SK) the coefficients of calcium iron vitamin A riboflavin and ascorbic acid were decreased Kurtosis (Ku) of iron and vitamin A was increased. On the whole distributions of nutrient intake of the farmers were changed in undesirable ways although the mean values of the nutrient intake were improved 4) In relationship analysis among 115 relationships 76 relationships were consistent between 1982 and 1987. Of 76 consistent relationships only 10 relationship were significant at 5% level such as the protein intake level and the balance of food intake calcium intake level and the age etc.

• Sijohaknonchong
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• v.42
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• pp.69-91
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• 2015

The aim of this paper is to examine the men's ideal lives and the aspects of variation in Sijo. In this paper the focus is two texts of Saseol-Sijo. One is the Saseol-Sijo without any known author, the other is the Saseol-Sijo written by Lee Jeong-bo. These works were enjoyed by many people to posterity, and they were played a variation. The first aspect of variation is the emphasis on men's magnanimous and amusable life. This aspect is thought to be a result of the interference of entertainment space. The second aspect of variation is to show the awareness of impossibility of riches and honors and belief in his alternative life. We can see the conflict between reality and desire. This case is thought to be enjoyed by the person who can sympathize with that situation. The third aspect of variation is to show the transcendence of desire for worldly success and the interest in a happy old age. This case is worthy of notice because it shows the interest in old age. This case expresses the desire for comfortable life or pleasure-seeking life, and it is thought to be more concerned with a concrete everyday life than an idea. Sometimes we can see the works that show reflection of his(her) life and mature attitude to life. More studies on these works should be done.

• Journal of Preventive Medicine and Public Health
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• v.20 no.1 s.21
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• pp.10-39
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• 1987

Mortality rate and causes of death are regarded as an index of strength as well as level of development of a country. However, there is no accurate data for the causes of death in Korea due to lack of systematic vital data collection system. The objective of this study was to define the causes of death of the school teachers, its changing pattern, cause-specific mortality rate, and geographic variation. The study population included all of the teachers in primary school, middle and high schools, and college who joined in Korean Teachers' Union between 1968 and 1985 that provided a total of 1,972, 069 person-years to observe (1,384,911 man-years, 587,158 woman-years). There were 3,678 deaths in this period (3,377 males, 301 females). The most common cause of death was neoplasm which was followed by the diseases of circulatory system. The proportion of death of neoplasm was 1.5 times higher than that of the general population. Causes of death were classified into 5 major groups (neoplasm, diseases of circulatory system, accidents and poisoning, diseases of liver, and all others). The mortality rates of diseases of circulatory system and all others for general population were 4 to S times higher than those for the teachers. However, mortality rates of neoplasm and diseases of liver were only about 2 times higher than those for teachers. Mortality rate of liver cancer for teachers was higher than gastric cancer mortality rate which is the reverse in general population. The crude death rate was 2.12 per 1,000 person-years for male and 1.00 for female which is one-third of the crude death rate of general population. Crude death rate of study population was higher in rural area than in urban area. However, mortality rate of neoplasm for male was higher in urban area than in rural area while mortality rates of all other causes were higher in rural area. For female, mortality rates of neoplasm and diseases of circulatory system were higher in urban area and the rates for all other causes were higher in rural area. Crude death rate was lowest in Gyeongin area and highest in Yeongnam area. The mortality of neoplasm for male accounted the highest proportion of all death in Gyeongin, Chungcheong and Yeoungnam areas while the mortality of neoplasm and mortality of circulatory system accounted the same proportion in Jeonra area. For female, the mortality of disease of circulatory system accounted the highest proportion in Gyeongin and Yeoungnam and Jeonra areas. Proportion of death due to accidents and poisoning was high in Chungcheong area and death due to all other causes was high in Yeoungnam area. The most common cause of death for male by city and province was neoplasm in Seoul, Busan, Daegu, Gyeonggi, Chungnam, Chungbuk, Gyeongnam and Gyeongbuk. Diseases of circulatory system was the leading cause of death in the rest of city and provinces. The leading cause of death for female was diseases of circulatory system in Seoul, Incheon, Chungbuk, Chungnam, and Gyeongbuk, neoplasm in Busan, and accident and poisons in all other cities and provinces. The mortality rates of male were above 2 per 1,000 person-years in Jeju, Gyeongbuk, Gyeongnam, Daegu, and Chungbuk, and it was below 1.5/l,000 in Seoul, Incheon and Gyeonggi. The mortality rate of female was above 1.2/1,000 person-years in Gyeongnam and Incheon while it was below 0.5/l,000 in Daegu, Geonggi Chungbuk and Jeju. The leading cause for male by school of employment was neoplasm in all levels of school with a remarkably higher rate in the professors of college. Leading cause of death for female was disease of circulatory system in primary schools, high schools and college but neoplasm in middle schools. There was no death due to liver diseases in middle and high school teachers and college professors and no death due to all other category in high school teachers and college professors, in females. High school teachers and the highest mortality rate and college professors showed the lowest mortality rate. Temporal trend of mortality was examined in three periods; period I ($1968{\sim}1974$), period II ($1975{\sim}1979$), and period III ($1980{\sim}1985$). The leading cause of death for male was diseases of circulatory system in period I and II but neoplasm in period III. Such trend of decreasing diseases of circulatory system and increasing neoplasm was observed in female. Overall mortality rate was decreased over the 3 periods. The mortality rates of diseases of circulatory system, liver disease and all others were decreased in male but the mortality rates of neoplasm and accident and posions was increased. Female showed a similar trend to male but the mortality rate of liver diseases was increased. Mortality rates of diseases of circulatory system, neoplasm and liver diseases increased with age of teachers up to 50 years of age but decreased in 60 years of age. Mean age at death due to each cause was higher in male than female by $4{\sim}10$ years. However, the mean age at death of the teachers was $2{\sim}5$ years lower than that of the general population in all causes of death and the sex difference in the mean a2e at death was smaller ($2{\sim}3$ years) in general population. In sex ratio of mortality, male was higher than female in almost all diseases except suicide and maintained a high ratio. The general population showed universally high ratio in male like teachers, and more or less did regular patterns in mortality with ratio smaller.