• YAKHAK HOEJI
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• v.44 no.2
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• pp.169-174
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• 2000

Pedunculagin is an ellagitannin purified from Alnus hirsuta var. microphylla. Betulaceae. The effects of pedunculagin on immune system have been characterized to induce enhancement of NK (natural killer) cell cytotoxicities against tumor cells. Here, we report the evaluation of the effects of pedunculagin on the growth of murine Bl6-F10 melanoma in vivo. After the intradermal inoculation of Bl6-F10 melanoma, Bl6-F10 tumors grew progressively in immunocompetent syngenic C57BL/6 mice. The mice treated with pedunculagin(10 mg/kg, every 48 hrs) resulted in a significant improvement in survival. Inhibitory effects of pedunculagin on lung metastasis in C57BL/6 mice were also detected. Summarizing treatment with pedunculagin has a significant antitumor effect upon Bl6-F10 murine melanoma.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.191.3-192
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• 2003

Alnus japonica (Betulaceae) has been traditionally used for purifying blood, and curing feces containing blood, enteritis, diarrhea, alcoholism and cut wounds. In the current work, activity guided isolation of the butanol fraction of the Alnus japonica bark led to the isolation of catechin-7-O-${\beta}$-D-apiofuranoside. Anti-inflammatory activity was determined with carrageenan-induced paw edema in mice as an acute inflammation, complete Freund's adjuvant-induced arthritis as a chronic inflammation. Carrageenan- induced paw edema in mice was significantly inhibited at 0.5, 1, 2, and 3 hr after carrageenan injection by administration of the flavonoid glycoside at the dose of 150mg/kg. (omitted)

• Journal of Life Science
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• v.10 no.1
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• pp.14-19
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• 2000

Variation at 25 allozyme loci in Korean wateralder (Alnus hirsuta Rupr.) from nine distinct populations was measured to estimate the amount and pattern of genetic diversity and population structure. The mean genetic diversity within population was 0.166. Korean alder populations have slightly high levels of genetic diversity compared to those present in associated temperature-zone species and two Canadian alder species. Among population s genetic differentiation accounted for an significant 9% of the total variation. High gene flow(Nm=2.63) was observed. Analysis of fixation indices, calculated for all polymorphic loci in each population, showed a substantial deficiency of heterozygotes relative to Hardy-Weinberg expectations. The mean GST value A. hirsuta in Korea (GST = 0.087) is similar to those of A. rogosa in Canada (GST = 0.052). These low values of GST in two countries. reflecting little spatial genetic differentiation, may indicate extensive gene flow (via pollen and/or seeds) and/or recent colonization. These factors reduce the effect of geographic isolation of breeding and the chance for genetic divergence. A pattern of increasing is observed with increasing rainfall per year. Regression analysis indicates that 54% (F = 4.67) of the variability observed can be explained by this relationship.

• Korean Journal of Environment and Ecology
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• v.11 no.3
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• pp.352-365
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• 1997

As a serials of researches for the restoration model of evergreen broad-leaved forests, the restoration strategies of the case study areas were proposed. Restoration type of vegetation were classified into an improvement type and a reconstruction type and a reconstruction type for Wando(Island). Improvement type of restoration was suggested for Mokdo(Island). Quercus acuta community, Q. salicina community, Neolitsea sericea community, Castanopsis cuspidata var. sieboldii community, Machilus thunbergii community, Cinnamomum japonicum community, etc. were suggested as a restoration goal of vegetation for Sando(Island). Machlus thunvergii community was suggested as a restoration goal of vegetation for Mokdo(Island). Also the species restoration olan of the Wando(Island) was prepared for Quercus salicina of Fagaceae and Ostrya japonica of Betulaceae those which the natural distribution and population size were very limited. There was no species which needed for species restoration urgently at Mokdo(Island).

• Korean Journal of Plant Resources
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• v.6 no.2
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• pp.99-124
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• 1993

Plant in chollabuk-do have investded 105 family, 442 species. 2. The order of distribution of the most family was the Compositae 43, Leguminosae Gramineae each 28, Rosaceae 17, Liliaceas 22, Labiatae 17, Ranunculaceae 12, Betulaceae 11, Violaceae 10, Polygonaceae Aspidiaceae each 9, Cruciferae${\cdot}$Caryothyllaceae${\cdot}$Celastraceae each 8, Fagaceae, Rubiaceae each 6, Ulmaceae 5. 3. Medical plants have invested 56 family, 116 species. 4. The order of the most family was the Compositae 8, Liliaceae Rosaceae${\cdot}$Umbelliferae${\cdot}$Labiatae each 6, Leguminosae${\cdot}$Rutaceae each 5, Campanulaceae${\cdot}$Ranunculaceae each 3, Simaroubaceae${\cdot}$Euphorbiaceae${\cdot}$Araliaceae each 2, Scrophulariaceae${\cdot}$Plantaginaceae each 1.

• The Korean Journal of Ecology
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• v.20 no.3
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• pp.163-168
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• 1997

Taxa of the herbivorus insect larvae and their foodplant species were surveyed in a temperate forest of Namhansansung Area, Sungnam City, Kyonggi Province, in 1994-1996 growing season, Sixty two taxa of insect larvae fed on leaves of 18 woody species in 11 families during three growing season. Larvae began to be detected from the mid-April when the leafing time began. The number of larvae taxa reached to the maximum value(32 taxa) early in May, 1994. It was the time that the value of specific leaf area reached to the maximum. It decreased up to 3-4 taxa in the mid-June. Taxa of insect larvae were different year by year even in the same season. Most of larvae fed on various plant species, suggesting that they were generalist or polyphagous species. Fagaceae, Betulaceae, Ulmaceae, Rosaceae. Aceraceae, Ericaceae, Oleaceae and Styracaceae were fed on by many taxa of insect larvae, while Euonymus spp. (Celastraceae). Lindera obtusiloba(Lauraceae) and Symplocos chinensis for. pilosa(Symplocaceae) were mainly fed on by a few taxon.. Erannis, Calospilos and Phigalia were observed to feed on various species, but Illiberis, Pryeria and Chalocosia fed on only Rosaceae, Euonymus spp.(Cerastraceae) and Symplocos chinensis for. pilosa(Symplocaceae), respectively. An unidentified larva was observed only on Lindera obtusiloba (Lauraceae).

• Journal of Environmental Science International
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• v.11 no.11
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• pp.1149-1156
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• 2002

The ecological characteristics of Dolbae trees, a valuable genetic resource for native pyrus fruit trees, were investigated at four naturally inhabited areas on Mount Kaya, Gyeongsangnam-Do. Most Dolbae trees were found on the southwest side of an old hiking path to a mountain valley at altitudes of 610∼670 m. The surrounding flora consisted of 46 families, 69 genera, 75 species, and 10 varieties. The natural habitat of the Dolbae trees was basically a deciduous broad-leaved forest with a predominance of Quercus serrata and ligneous plants(xylophytes) from the Fagaceae and Betulaceae families. The habitat was also found to be in a second transition resulting from forest disturbance and exhibited a degree of diversity of 2.901-5.065, based on Shannon-Weiner's index. Examination of the Dolbae trees found in Mount Kaya revealed diameter breast heights(DBHs) ranging from 10 to 60 cm, including six old and large Dolbae trees with a DBH of 50∼60 cm, which will be particularly valuable as a genetic resource. Accordingly, the current results suggest that the study areas are a secondary forest in a typical mid-temperate zone resulting from forest damage about 10 years earlier.

• Journal of Korean Society of Forest Science
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• v.52 no.1
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• pp.50-57
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• 1981

Occurrence of ectomycorrhizae in the selected woody plants growing in Korea was surveyed and compared with that reported in the literature. Ectomycorrhizae were common features in Pinaceae, Salicaceae, Betulaceae, Fagaceae, Ulmaceae, and Tiliaceae, which agreed with literature. We were unable to find ectomycorrhizae in Cupressaceae, Juglans, Rosaceae, and Acer which were reported to have facultative ectomycorrhizae. Other species observed did not have ectomycorrhizae.

• Archives of Pharmacal Research
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• v.25 no.4
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• pp.493-499
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• 2002

We investigated the antitumor activity of oregonin, a diarylheptanoid derivative purified from Alnus hirsuta Turcz, Betulaceae. Oregonin is a potential novel immunomodulator, which augments the activation of natural killer (NK) cells, and thereby leads to a powerful antitumor activity. To evaluate the cytotoxicity of oregonin against tumor cells, we examined the effectiveness of NK cells and determined that oregonin could increase NK cell cytotoxicity. This was confirmed by MTT assay. In addition, the survival time of C57BL/6 mice were measured by inoculating 816-F10 melanoma cells to mice via intra muscular (i.m.) injection. Oregonin treatment after 10 hours of inoculation at 10 mg/kg dosage showed a significant extension of survival time by up to 51.32%, when compared to the control group. Moreover, oregonin significantly reduced the incidence of pulmonary metastasis, which may be developed from 816-F10 melanoma cells. These findings suggest that oregon in may be classified as a new and novel immunomodulator due to its potential antitumor activity.

• Journal of the Korean Wood Science and Technology
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• v.31 no.2
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• pp.45-51
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• 2003

One flavonoid, lignan glycosides and two diarylheptanoids were isolated from the sapwood of Betula maximowicziana. The structures were determined as : catechin 7-O-𝛽-D-xylopyranoside, lyoniresinol 9'-O-𝛽-D-glucopyranoside, 11-oxo-3, 8, 12, 17-tetrahydroxy-9-ene[7, 0]-metacyclophane and 11-oxo-3, 8, 9, 10, 12, 17-hexahydroxy[7, 0]-metacyclophane, respectively, on the basis of spectrosopic data and chemical correlations.