• Journal of the Korean Statistical Society
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• 제24권2호
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• pp.337-347
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• 1995

In the problem of some sequential estimation, the stopping times may be written in the form $N(c) = inf{n \geq n_0; n \geq c^2 S^2_n/\delta^2 (\bar{X}_n)}$ where ${s^2_n}$ and ${\bar{X}_n}$ are the sequences of sample variance and sample mean of the independently and identically distributed (i.i.d.) random variables with distribution $F_{\theta}(x), \theta \in \Theta$, respectively, and $\delta$ is either constant or any given positive real valued function. We obtain some asymptotic normality and asymptotic expectation of the N(c) in various limiting situations. Specially, uniform asymptotic normality and uniform asymptotic expectation of the N(c) are given.

• 에너지공학
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• 제1권1호
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• pp.97-101
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• 1992

A mathematical model has been developed for an analytical calculation of distribution coefficient (K$_1$) in the presence of a chelating agent, The newley formulated K$\_$D/ is given as a function of the mole fraction of a free metal ion in the solution, ${\beta}$, and will serve as an alternative for the tedious individual measurements of K$\_$D/. This formulation will be used to analyze the effects of the presence of chelating agents on the adsorption capacity of geologic media such as clay minerals and soils. The present method may be a significant progess for the evaluation of the transport phenomena and separation processes of metal ions (or radionuclides) in the presence of chelating agents.

• Animal cells and systems
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• 제12권3호
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• pp.127-136
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• 2008

Caspase-11 has been known as a dual regulator of cytokine maturation and apoptosis. Although the role of caspase-11 under pathological conditions has been well documented, its physiological role has not been studied much. In the present study, we investigated a possible physiological function of caspase-11 during immune response. In the absence of caspase-11, immunized spleen displayed increased cellularity and abnormal germinal center structure with disrupted microarchitecture. The rate of cell proliferation and apoptosis in the immunized spleen was not changed in the caspase-11-deficient mice. Furthermore, the caspase-11-deficient peritoneal macrophages showed normal phagocytotic activity. However, caspase-11-/-splenocytes and macrophages showed defective migrating capacity. The dysregulation of cell migration did not seem to be mediated by caspase-3, interleukin-$1{\alpha}$ or interleukin-$1{\beta}$ which acts downstream of caspase-11. These results suggest that a direct regulation of immune cell migration by caspase-11 is critical for the formation of germinal center microarchitecture during immune response. However, humoral immunity in the caspase-11-deficient mice was normal, suggesting the formation of germinal center structure is not essential for the affinity maturation of the antibodies.

• The Korean Journal of Pain
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• 제8권2호
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• pp.331-335
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• 1995

Asthma is a disease of the airways that is characterized by increased responsiveness of the tracheobronchial tree to a multiplicity of stimuli. A number of causes have been postulated for the increased airway reactivity of asthma is conservative as beta-adrenergic agonist, methylxanthines, glucocorticoids, anticholinergics and mast cell stabilizing agent. Stellate ganglion block for the treatment of bronchial asthma has its controversies. Stellate ganglion block was performed for the treatment of 3 patients with bronchial asthma. After stellate ganglion blocks, dyspnea, coughing and wheezing was markedly reduced. Lung function test improved with 1 st case. Two asthma cases were able to discontinue medication for asthma. No severe aggrevation of bronchial symptoms were noted after stellate ganglion blocks. It suggested that stellate ganglion block can be safely performed on bronchial asthmatic patients.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2001년도 춘계학술대회 논문집
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• pp.222-227
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• 2001

The time simulation of slow drift motions of moored FPSO in waves is presented. The equation of motion based on Cummin's theory of impulse responses are employed, and are consisted of horizonal plane -surge, sway and yaw. The added mass coefficients, wave damping coefficients, first order wave exciting forces and the second order wave drift forces involved in the equations are obtained from a three-dimensional panel method in the frequency domain. The mooring lines are modeled quasistatically as catenary for chains and touchdown. As for numerical example, time domain analyses are carried out for a box-type FPSO in long crest irregular wave condition.

• 한국해양공학회지
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• 제18권2호
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• pp.64-69
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• 2004

The characteristics of the probability distribution for mechanical properties, e.g. tensile strength, reduction of area, and elongation, for STS304 stainless steel in elevated temperature are investigated. Tensile test is performed by constant crosshead speed controls with 1mm/min. The probability distribution function of measured mechanical properties seems to follow $\alpha$ 3-parameter Weibull, and shows a slight dependence on the temperature. When the temperature is raised, the shape parameter a is increased, but both the scale parameter $\beta$ and location parameter v are decreased.

• 산업공학
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• 제16권spc호
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• pp.39-44
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• 2003

As one of many design variables, the role of dimension tolerances is to restrict the amount of size variation in a manufactured feature while ensuring functionality. In this study, a nonlinear integer model has been modeled to allocate the optimal tolerance to each individual feature at a minimum manufacturing cost. While a normal distribution determines statistically worst tolerances with its symmetrical property in many previous tolerance allocation studies, a asymmetrical distribution is more realistic because its mean is not always coincident with a process center. A nonlinear integer model is modeled to allocate the optimal tolerance to a feature based on a beta distribution at a minimum total cost. The total cost as a function of tolerances is defined by machining cost and quality loss. After the convexity of manufacturing cost is checked by the Hessian matrix, the model is solved by the Complex Method. Finally, a numerical example is presented demonstrating successful model implementation for a nonlinear design case.

• 한국지진공학회논문집
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• 제4권4호
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• pp.117-123
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• 2000

열차와 교량의 3차원 모델링을 사용한 고속철도 교량의 동적해석이 수행되었다. 철도교의 모델인은 판요소와 3차원 뼈대요소로 모델링되었다. 상판과 주형 사이의 offset은 기하학적인 구속조건을 사용하여 고려하였다. 본 연구에서 사용된 고속철도는 2량의 동력차와 2량의 모터차와 16량의 객차로 구성되어 있다. 관절형 대차로 연결되어 전체 열차계의 운동방정식은 Lagrange 방정식을 이용하여 유도되었으며, 차제와 대차 그리고 자축의 3차원인 운동을 고려하였다. 이동 열차에 의한 교량의 응답은 predictor-corrector 반복법에 의한 Newmark-$\beta$ 법에 의해서 그 해가 구해진다. 매개변수해석에 의해서 열차의 이상화방법, 열차의 제동, 철도교량의 주행면 조도에 의한 영향이 고찰되었다.

• Animal cells and systems
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• 제6권4호
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• pp.323-326
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• 2002

One hundred and three random complementary DNA clones representing rainbow trout intestine were par1i811y sequenced as an approach to analyze the transcribed sequences of its genome. Of the sequences generated, 60.0% of the ESTs were represented by 40 known genes. Thirty-five clones of unknown gene products potentially represented 34 novel genes. The most Bbundantly represented messages were the 28S ribosomal protein (6.5%) and beta actin (5.8%). The genes involved in ribosome formation (18%) accounted for the major gene expression. Development of EST panels representing the genes expressed in a particular tissue will be useful in determining the role of these genes in normal function and in response to developmental, hormonal, environmental and physiological changes.

• Structural Engineering and Mechanics
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• 제42권4호
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• pp.449-469
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• 2012

For generally damped linear systems with repeated eigenvalues and defective eigenvectors, this study provides a decomposition method based on residue matrix, which is suitable for engineering applications. Based on this method, a hybrid approach is presented, incorporating the merits of the modal superposition method and the residue matrix decomposition method, which does not need to consider the defective characteristics of the eigenvectors corresponding to repeated eigenvalues. The method derived in this study has clear physical concepts and is easily to be understood and mastered by engineering designers. Furthermore, this study analyzes the applicability of step-by-step methods, including the Newmark beta and Runge-Kutta methods for dynamic response calculation of defective systems. Finally, the implementation procedure of the proposed hybrid approach is illustrated by analyzing numerical examples, and the correctness and the effectiveness of the formula are judged by comparing the results obtained from the different methods.