• Journal of the Korean Institute of Intelligent Systems
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• v.19 no.6
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• pp.809-813
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• 2009

We want to show that the construct of best fuzzy tests for certain fuzzy situations of Poisson distribution. Due to Neyman and Pearson theorem, if we have ${\theta}_0$ and ${\theta}_1$ be distinct fuzzy values of ${\Omega}=\{{\theta}\;:\;{\theta}\;=\;{\theta}_0,\;{\theta}_1\}$ such that $L({\theta}_0\;:\;X)/L({\theta}_1\;:\;X)$ < k, then k is a fuzzy number. For each fuzzy random samples point $X\;{\subset}\;C$, we have most power test for fuzzy critical region C by agreement index.

• Journal of Yeungnam Medical Science
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• v.25 no.2
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• pp.85-91
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• 2008

Intensity-modulated radiation therapy (IMRT) is believed to be one of the best radiation treatment techniques. IMRT is able to deliver fatal doses of radiation to the tumor region with minimal exposure of critical organs. It is essential to have a comprehensive quality assurance program to assure precision and accuracy in treatment, due to the character of IMRT. We applied quality assurance technique to the Eclipse treatment planning system and sought to determine its effectiveness in patient treatment planning. An acrylic phantom, film, and an ionization chamber were used in this study.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.697-699
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• 2004

Stochastic Neighbor Embedding(SNE) is a probabilistic method of mapping high-dimensional data space into a low-dimensional representation with preserving neighbor identities. Even though SNE shows several useful properties, the gradient-based naive SNE algorithm has a critical limitation that it is very slow to converge. To overcome this limitation, faster optimization methods should be considered by using trust region method we call this method fast TR SNE. Moreover, this paper presents a couple of useful optimization methods(i.e. conjugate gradient method and Newton's method) to embody fast SNE algorithm. We compared above three methods and conclude that TR-SNE is the best algorithm among them considering speed and stability. Finally, we show several visualizing experiments of TR-SNE to confirm its stability by experiments.

• Advances in aircraft and spacecraft science
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• v.7 no.3
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• pp.215-228
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• 2020

As is shown in the paper, the Koltunov-Rzhanitsyn singular kernel of heredity (when constructing mathematical models of the dynamics problem of the hereditary theory of viscoelasticity) adequately describes real mechanical processes, best approximates experimental data for a long period of time. A mathematical model of the problem of the flutter of viscoelastic plates moving in a gas with a high supersonic velocity is given. Using the Bubnov-Galerkin method, discrete models of the problem of the flatter of viscoelastic plates flowed over by supersonic gas flow are obtained. A numerical method is developed to solve nonlinear integro-differential equations (IDE) for the problem of the hereditary theory of viscoelasticity with weakly singular kernels. A general computational algorithm and a system of application programs have been developed, which allow one to investigate the nonlinear dynamic problems of the hereditary theory of viscoelasticity with weakly singular kernels. On the basis of the proposed numerical method and algorithm, nonlinear problems of the flutter of viscoelastic plates flowed over in a gas flow at an arbitrary angle are investigated. In a wide range of changes in various parameters of the plate, the critical velocity of the flutter is determined. It is shown that the singularity parameter α affects not only the oscillations of viscoelastic systems, but the critical velocity of the flutter as well.

• Korean Journal of Agricultural and Forest Meteorology
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• v.4 no.2
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• pp.127-132
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• 2002

All the countries in RA II (Asia Region in WMO) welcome the establishment of a Web site dedicated to agricultural meteorology, because it is believed that the best way to improve and speed up the flow of information is the use of the Internet and the establishment of a Web site. In providing recommendation for the promotion and improvement of the AgroMeteorological service in RA II, a couple of key suggestions were proposed: (a) Exchanges of data and AgroMeteorological knowledge between member countries and between RAs, (b) Exchanges of experts between member countries as a necessary way to share the knowledge, and (c) Joint research between member countries to solve common problems in AgroMeteorological affairs. In order to meet the above requirements for RA II, an AgroMeteorological information network will be the most critical and dynamic aspect in sustainable agriculture in this region. In addition, the establishment of a Core AgroMeteorological station, recommended by CAgM of WMO, will require its own information sharing systems for communication among member countries. Inevitable use of information technologies (IT) such as information networks, databases, simulation models, GIS, and RS for regional impact assessment of environmental change on AgroEcosystem will be enforced. Thus, the regional Internet-based Agrometeorological information network has been in place since 1999, though all contributions to it have been volunteered by individuals, institutes, universities, etc.

• Journal of Korean Vacuum Science & Technology
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• v.3 no.2
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• pp.112-115
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• 1999

The real ($\varepsilon$1) and imaginary ($\varepsilon$2) parts of the dielectric function of ZnS have been measured by spectroscopic ellipsometry (SE) in the 3.7-6.0 eV photon-energy range at room temperature. The obtained dielectric function spectra reveal distinct structures at energies E0/(E0+$\Delta$0) and E1 critical points. The spectrum after chemical treatment to remove surface oxide overlayer showed that these data seem to be the best representation of the dielectric function of ZnS, having the largest $\varepsilon$2 value at E1 peak region reported so far by SE. Dielectric-related optical constants of ZnS, such as the complex refractive indices (n+n=ik), absorption coefficient, and reflectance, are also presented.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.25-32
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• 2023

Recognizing the size and location of prostate cancer is critical for prostate cancer diagnosis, treatment, and predicting prognosis. This paper proposes a model to classify the tumor region and normal tissue with cross-sectional visual images of prostatectomy tissue. We used specimen images of 44 prostate cancer patients who received prostatectomy at Gachon University Gil Hospital. A total of 289 prostate slice images consist of 200 slices including tumor region and 89 slices not including tumor region. Images were divided based on the presence or absence of tumor, and a total of 93 features from each slice image were extracted using Radiomics: 18 first order, 24 GLCM, 16 GLRLM, 16 GLSZM, 5 NGTDM, and 14 GLDM. We compared feature selection techniques such as LASSO, ANOVA, SFS, Ridge and RF, LR, SVM classifiers for the model's high performances. We evaluated the model's performance with AUC of the ROC curve. The results showed that the combination of feature selection techniques LASSO, Ridge, and classifier RF could be best with an AUC of 0.99±0.005.

• Journal of the Earthquake Engineering Society of Korea
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• v.28 no.3
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• pp.121-128
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• 2024

There are growing concerns that the recently implemented Earthquake Early Warning service is overestimating the rapidly provided earthquake magnitudes (M). As a result, the predicted damages unnecessarily activate earthquake protection systems for critical facilities and lifeline infrastructures that are far away. This study is conducted to improve the estimation accuracy of M by incorporating the observed S-wave seismograms in the near source region after removing the site effects of the seismograms in real time by filtering in the time domain. The ensemble of horizontal S-wave spectra from at least five seismograms without site effects is calculated and normalized to a hypocentric target distance (21.54 km) by using the distance attenuation model of Q(f)=348f^0.52 and a cross-over distance of 50 km. The natural logarithmic mean of the S-wave ensemble spectra is then fitted to Brune's source spectrum to obtain the best estimates for M and stress drop (SD) with the fitting weight of 1/standard deviation. The proposed methodology was tested on the 18 recent inland earthquakes in South Korea, and the condition of at least five records for the near-source region is sufficiently fulfilled at an epicentral distance of 30 km. The natural logarithmic standard deviation of the observed S-wave spectra of the ensemble was calculated to be 0.53 using records near the source for 1~10 Hz, compared to 0.42 using whole records. The result shows that the root-mean-square error of M and ln(SD) is approximately 0.17 and 0.6, respectively. This accuracy can provide a confidence interval of 0.4~2.3 of Peak Ground Acceleration values in the distant range.

• Journal of Pharmaceutical Investigation
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• v.29 no.3
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• pp.193-203
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• 1999

In order to investigate systematically the steady shear flow properties of aqueous po1y(ethylene oxide) (PEO) solutions having various molecular weights and concentrations, the steady flow viscosity has been measured with a Rheometrics Fluids Spectrometer (RFS II) over a wide range of shear rates. The effects of shear rate, concentration, and molecular weight on the steady shear flow properties were reported in detail from the experimentally measured data, and then the results were interpreted using the concept of a material characteristic time. In addition, some flow models describing the non-Newtonian behavior (shear-thinning characteristics) of polymeric liquids were employed to make a quantitative evaluation of the steady flow behavior, and the applicability of these models was examined by calculating the various material parameters. Main results obtained from this study can be summarized as follows: (1) At low shear rates, aqueous PEO solutions show a Newtonian viscous behavior which is independent of shear rate. At shear rate region higher than a critical shear rate, however, they exhibit a shear-thinning behavior, demonstrating a decrease in steady flow viscosity with increasing shear rate. (2) As an increase in concentration and/or molecular weight, the zero-shear viscosity is increased while the Newtonian viscous region becomes narrower. Moreover, the critical shear rate at which the transition from the Newtonian to shear-thinning behavior occurs is decreased, and the shear-thinning nature becomes more remarkable. (3) Aqueous PEO solutions show a Newtonian viscous behavior at shear rate range lower than the inverse value of a characteristic time $1/{\lambda}_E$, while they exhibit a shear-thinning behavior at shear rate range higher than $1/{\lambda}_E$. For aqueous PEO solutions having a broad molecular weight distribution, the inverse value of a characteristic time is not quantitatively equivalent to the critical shear rate, but the power-law relationship holds between the two quantities. (4) The Cross, Carreau, and Carreau-Yasuda models are all applicable to describe the steady flow behavior of aqueous PEO solutions. Among these models, the Carreau-Yasuda model has the best validity.

• Microbiology and Biotechnology Letters
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• v.49 no.1
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• pp.65-74
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• 2021

Serine proteases are the most versatile proteolytic enzymes with tremendous applications in various industrial processes. This study was designed to investigate the biochemical properties, critical residues, and the catalytic potential of alkaline serine protease using in-silico approaches. The primary sequence was analyzed using ProtParam, SignalP, and Phyre2 tools to investigate biochemical properties, signal peptide, and secondary structure, respectively. The three-dimensional structure of the enzyme was modeled using the MODELLER program present in Discovery Studio followed by Molecular Dynamics simulation using GROMACS 5.0.7 package with CHARMM36m force field. The proteolytic potential was measured by performing docking with casein- and keratin-enriched residues, while the effect of the inhibitor was studied using phenylmethylsulfonyl fluoride, (PMSF) applying GOLDv5.2.2. Molecular weight, instability index, aliphatic index, and isoelectric point for serine protease were 39.53 kDa, 27.79, 82.20 and 8.91, respectively. The best model was selected based on the lowest MOLPDF score (1382.82) and DOPE score (-29984.07). The analysis using ProSA-web revealed a Z-score of -9.7, whereas 88.86% of the residues occupied the most favored region in the Ramachandran plot. Ser327, Asp138, Asn261, and Thr326 were found as critical residues involved in ligand binding and execution of biocatalysis. Our findings suggest that bioengineering of these critical residues may enhance the catalytic potential of this enzyme.