• 제목/요약/키워드: benefit function

검색결과 403건 처리시간 0.031초

The Probiotic Effects of the Saccharomyces cerevisiae 28-7 Strain Isolated from Nuruk in a DSS-Induced Colitis Mouse Model

  • Lee, Jang Eun;Lee, Eunjung
    • Journal of Microbiology and Biotechnology
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    • 제32권7호
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    • pp.877-884
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    • 2022
  • Probiotics are microorganisms that can benefit host health when ingested in a live state, and lactic acid bacteria are the most common type. Among fungi, Saccharomyces boulardii (SB) is the only strain known to have a probiotic function with beneficial effects on colitis; however, information on other probiotic yeast strains is limited. Therefore, this study aimed to discover yeast strains expressing intestinal anti-inflammatory activities by exhibiting probiotic properties in dextran sodium sulfate (DSS)-induced colitis mice model. Nuruk (Korean traditional fermentation starter) containing various microbial strains was used as a source for yeast strains, and S. cerevisiae 28-7 (SC28-7) strain was selected with in vitro and in vivo characteristics to enable survival in the intestines. After 14 days of pretreatment with the yeast strains, DSS was co-administered for six days to induce colitis in mice. The results revealed that the disease activity index score was lowered by SC28-7 treatment compared to the DSS group, and the colon length and weight/length ratio were recovered in a pattern similar to that of the normal group. SC28-7 administration significantly reduced the secretion of pro-inflammatory cytokines in the serum and modified the mRNA expression of inflammatory cytokines (interleukin-1β, transforming growth factor-β, and interferon-γ) and proteins involved in gut barrier functions (mucin 2, mucin 3, zonula occludens-1, and occludin) in colon tissues. These results indicate that SC28-7 attenuates DSS-induced colon damage and inflammation, supporting its future use as a probiotic yeast for treating and preventing intestinal inflammatory diseases such as inflammatory bowel disease.

스마트 모빌리티 서비스를 위한 비용추정 (A Study on Cost Estimation for Smart Mobility Service)

  • 천서형;김동연;안재현;박규홍
    • 디지털융복합연구
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    • 제19권11호
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    • pp.301-313
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    • 2021
  • 자동차 산업은 차량 소유에서 공유로, 그리고 제조에서 서비스로의 패러다임 전환을 맞이하고 있다. 그러나 스마트 모빌리티 서비스의 경제적 가치가 항상 사용자에게 긍정적이라고 단정하기는 어렵다. 차량 소유 또는 공유와 관련된 비용은 서비스 혜택의 관점뿐만 아니라 잠재적인 사용자의 관점에서도 추정하기가 매우 어렵다. 따라서 본 연구는 비용 측면에 초점을 맞춰 전동화, 첨단 운전 보조 시스템(ADAS), 그리고 승차 공유 서비스 참여라는 세 가지 주요 요소를 기반으로 비용 추정 모델을 개발한다. 모델 분석 결과 단순 비용의 관점에서는 전동화, 승차 공유 참여 등 비용 혜택을 받는 경우 결과적으로 낮은 비용이 추정되었고, 추가로 민감도 분석을 통한 다양한 요인에 대한 분석을 시행하였다. 본 연구의 결과는 스마트 모빌리티 서비스 시장에서 잠재적 사용자와 제조업체를 위한 비용 예측 및 전략에 대한 유용한 통찰력을 제공할 수 있다.

상악 무치악 환자에서 전방부 임플란트 지지 고정성 보철물을 이용한 임플란트 보조 국소의치 수복 증례 (Implant-assisted removable partial denture in a maxillary edentulous patient: A case report)

  • 강현모;김지환;김재영
    • 대한치과보철학회지
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    • 제60권4호
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    • pp.442-452
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    • 2022
  • 무치악 환자의 구강 재건을 위한 임플란트를 활용한 치료 계획으로는 임플란트 지지 고정성 가공 의치, 임플란트 피개 의치, 임플란트 보조 국소의치 등이 있으며, 각각의 방식에 대한 적응증과 장단점이 다양하다. 본 증례의 환자는 상악 국소의치의 모든 잔존 지대치의 발거가 필요했으며 후방부 잔존골이 부족하여 식립 가능한 임플란트의 개수가 한정적이었다. 따라서 골 지지가 양호한 전방부에 4개의 임플란트 식립하여 임플란트 지지 서베이드 크라운과 후방연장 임플란트 보조 국소의치로 수복해주었고 환자에게 경제적으로 효과적이면서도 심미적, 기능적으로 만족스러운 결과를 제공하였다. 상악 무치악 환자에게 이와 같은 치료 계획은 경우에 따라 임플란트 피개의치의 대안으로 사용될 수 있으며 임상적, 생역학적 유효성을 검증하기 위해 더 많은 연구가 필요하다.

Musical Aptitude as a Variable in the Assessment of Working Memory and Selective Attention Tasks

  • Nisha, Kavassery Venkateswaran;Neelamegarajan, Devi;Nayagam, Nishant N.;Winston, Jim Saroj;Anil, Sam Publius
    • 대한청각학회지
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    • 제25권4호
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    • pp.178-188
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    • 2021
  • Background and Objectives: The influence of musical aptitude on cognitive test performance in musicians is a long-debated research question. Evidence points to the low performance of nonmusicians in visual and auditory cognitive tasks (working memory and attention) compared with musicians. This cannot be generalized to all nonmusicians, as a sub-group in this population can have innate musical abilities even without any formal musical training. The present study aimed to study the effect of musical aptitude on the working memory and selective attention. Subjects and Methods: Three groups of 20 individuals each (a total of 60 participants), including trained-musicians, nonmusicians with good musical aptitude, and nonmusicians with low musical aptitude, participated in the present study. Cognitive-based visual (Flanker's selective attention test) and auditory (working memory tests: backward digit span and operation span) tests were administered. Results: MANOVA (followed by ANOVA) revealed a benefit of musicianship and musical aptitude on backward digit span and Flanker's reaction time (p<0.05). Discriminant function analyses showed that the groups could be effectively (accuracy, 80%) segregated based on the backward digit span and Flanker's selective attention test. Trained musicians and nonmusicians with good musical aptitude were distinguished as one cluster and nonmusicians with low musical aptitude formed another cluster, hinting the role of musical aptitude in working memory and selective attention. Conclusions: Nonmusicians with good musical aptitude can have enhanced working memory and selective attention skills like musicians. Hence, caution is required when these individuals are included as controls in cognitive-based visual and auditory experiments.

Musical Aptitude as a Variable in the Assessment of Working Memory and Selective Attention Tasks

  • Nisha, Kavassery Venkateswaran;Neelamegarajan, Devi;Nayagam, Nishant N.;Winston, Jim Saroj;Anil, Sam Publius
    • Journal of Audiology & Otology
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    • 제25권4호
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    • pp.178-188
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    • 2021
  • Background and Objectives: The influence of musical aptitude on cognitive test performance in musicians is a long-debated research question. Evidence points to the low performance of nonmusicians in visual and auditory cognitive tasks (working memory and attention) compared with musicians. This cannot be generalized to all nonmusicians, as a sub-group in this population can have innate musical abilities even without any formal musical training. The present study aimed to study the effect of musical aptitude on the working memory and selective attention. Subjects and Methods: Three groups of 20 individuals each (a total of 60 participants), including trained-musicians, nonmusicians with good musical aptitude, and nonmusicians with low musical aptitude, participated in the present study. Cognitive-based visual (Flanker's selective attention test) and auditory (working memory tests: backward digit span and operation span) tests were administered. Results: MANOVA (followed by ANOVA) revealed a benefit of musicianship and musical aptitude on backward digit span and Flanker's reaction time (p<0.05). Discriminant function analyses showed that the groups could be effectively (accuracy, 80%) segregated based on the backward digit span and Flanker's selective attention test. Trained musicians and nonmusicians with good musical aptitude were distinguished as one cluster and nonmusicians with low musical aptitude formed another cluster, hinting the role of musical aptitude in working memory and selective attention. Conclusions: Nonmusicians with good musical aptitude can have enhanced working memory and selective attention skills like musicians. Hence, caution is required when these individuals are included as controls in cognitive-based visual and auditory experiments.

The effects of complex decongestive therapy on pain and functionality in individuals with breast cancer who developed adhesive capsulitis due to lymphedema: an evaluation by an isokinetic computerized system

  • Tatar, Konca Kaya;Turhan, Begumhan
    • The Korean Journal of Pain
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    • 제35권3호
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    • pp.280-290
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    • 2022
  • Background: This study aimed to determine the impact of complex decongestive therapy applications on upper extremity function in breast cancer patients who developed adhesive capsulitis after lymphedema. Methods: Thirty patients who developed adhesive capsulitis due to lymphedema were divided into two groups as study (n = 15) and control (n = 15) groups. Both groups received 20 minutes of exercise five days a week for three weeks using a Biodex isokinetic dynamometer, as well as a hot pack and TENS (Transcutaneous Electrical Nerve Stimulation) treatment to the shoulder joint. The study group received 45 minutes of intensive decongestive therapy along with the adhesive capsulitis treatment. The visual analogue scale was used to assess pain, circumference, and volumetric measurements were used to assess edema, and the Arm, Shoulder, and Hand Problems Questionnaire (DASH: Disabilities of the Arm, Shoulder, and Hand) was used to assess upper extremity functionality. The shoulder range of motion was evaluated. Results: Both groups had improvements in pain (P < 0.001), shoulder joint range of motion (P < 0.001), and upper extremity functionality (P < 0.001) after the treatment. There was a significant decrease in circumference and volumetric measurements in the study group (P < 0.001). However, no differences were seen in measurements in the control group. Conclusions: The results showed that complex decongestive therapy was beneficial in reducing lymphedema in breast cancer patients who acquired adhesive capsulitis due to lymphedema. Consequently, the authors believe that supplementing conventional physiotherapy with complex decongestive therapy will benefit patients.

영농형 태양광 시스템에서의 스마트 농업을 위한 의사결정지원시스템 (A Decision Support System for Smart Farming in Agrophotovoltaic Systems)

  • 김영진;소준용;온영재;이재윤;이재윤
    • 산업경영시스템학회지
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    • 제45권4호
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    • pp.180-186
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    • 2022
  • Agrophotovoltaic (APV) system is an integrated system producing crops as well as solar energy. Because crop production underneath Photovoltaic (PV) modules requires delicate management of crops, smart farming equipment such as real-time remote monitoring sensors (e.g., soil moisture sensors) and micro-climate monitoring sensors (e.g., thermometers and irradiance sensors) is installed in the APV system. This study aims at introducing a decision support system (DSS) for smart farming in an APV system. The proposed DSS is devised to provide a mobile application service, satellite image processing, real-time data monitoring, and performance estimation. Particularly, the real-time monitoring data is used as an input of the DSS system for performance estimation of an APV system in terms of production yields of crops and monetary benefit so that a data-driven function is implemented in the proposed system. The proposed DSS is validated with field data collected from an actual APV system at the Jeollanamdo Agricultural Research and Extension Services in South Korea. As a result, farmers and engineers enable to efficiently produce solar energy without causing harmful impact on regular crop production underneath PV modules. In addition, the proposed system will contribute to enhancement of the smart farming technology in the field of agriculture.

APMS 활용을 통한 항공기 연비향상 및 기대효과 (Aircraft Fuel Efficiency Improvement and Effect through APMS)

  • 유재림
    • 한국항공운항학회지
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    • 제31권2호
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    • pp.81-88
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    • 2023
  • SHM (Structural Health Monitoring) technique for monitoring aircraft structural health and damage, EHM (Engine Health Monitoring) for monitoring aircraft engine performance, and APM (Application Performance Management) is used for each function. APMS (Airplane Performance Monitoring System) is a program that comprehensively applies these techniques to identify the difference between the performance manual provided by the manufacturer and the actual fuel mileage of the aircraft and reflect it in the flight plan. The main purpose of using APMS is to understand the performance of each aircraft, to plan and execute flights in an optimal way, and consequently to reduce fuel consumption. First, it is to check the fuel efficiency trend of each aircraft, check the correlation between the maintenance work performed and the fuel mileage, find the cause of the fuel mileage increase/decrease, and take appropriate measures in response. Second, it is to find the cause of fuel mileage degradation in detail by checking the trends by engine performance and fuselage drag effect. Third, the APMS is to be used in making maintenance work decisions. Through APMS, aircraft with below average fuel mileage are identified, the cause of fuel mileage degradation is identified, and appropriate corrective actions are determined. Fourth, APMS data is used to analyze the economic analysis of equipment installation investment. The cost can be easily calculated as the equipment installation cost, but the benefit is fuel efficiency improvement, and the only way to check this is the manufacturer's theory. Therefore, verifying the effect after installation and verifying the economic analysis is to secure the appropriateness of the investment. Through this, proper investment in fuel efficiency improvement equipment will be made, and fuel efficiency will be improved.

'Magic Imperialism': The Logic of Magic in Edith Nesbit's Fantasy Novels

  • Park, Sojin
    • 영어영문학
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    • 제56권3호
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    • pp.501-517
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    • 2010
  • This paper examines the British imperialism found in Edith Nesbit's fantasy stories by looking at the function of magic and of the hierarchical relationships seen in the books. Although Edith Nesbit is relatively unknown in Korea, she is widely recognized as having had a great influence on the 20th century British literary world, and is also well-known for her political position as a socialist. Nesbit's fantasy books are commonly differentiated from other Victorian children's books written before her in that she created realistic and liberal children characters and rejected the adult didactic tone. While Nesbit's books have been recognized as revolutionary and being distinguished from other Victorian children's books, I suggest that the ideas found in her fantasy novels largely include the dominant Victorian message of British imperialism. This imperial ideology is delivered by the logic of magic and the multilateral hierarchies. The two magic creatures (The Psammead and the Phoenix) and the two magic items from an Oriental background (the Carpet and the Amulet) all have a magic power to grant people's wishes, wholeheartedly exercising their power and knowledge for the sake of the British characters. While the magic agents serve to fulfill the children's wishes, the children aim to please their parents and to benefit their family, showing layered hierarchies among the characters. Also, there is a hierarchical distinction between the magic items and the magic creatures in that the magic items have no voice to express themselves but only serve and obey the British children. The foreign characters that the children encounter in their adventures also cooperate with the British characters to help them to fulfill their goals. In short, magic frees the children from the adult-centered world but ultimately their free adventures serve their parents and other adults, and represent the ideals and hierarchical concepts of British imperialism. Thus, Nesbit's position as a modern writer seems to be ambiguous, switching between modern characterization and style, and the old Victorian imperial messages that also exist in her fantasy novels.

유방암 생존자의 라인댄스 참여효과에 대한 현상학적 연구 (The Effect of Breast Cancer Survivors' Participation in Line Dance: A Phenomenological Study)

  • 강민재;변지용;박지혜;유미성;황서현;전용관
    • 한국체육학회지인문사회과학편
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    • 제56권6호
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    • pp.541-559
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    • 2017
  • 본 연구는 라인댄스 프로그램에 참여한 유방암 생존자들을 대상으로 라인댄스 프로그램 참여 경험과 그 효과를 알아보는데 목적이 있다. 연구 참여자는 유목적 표집 방법에 따라 9명을 선정하였다. 자료는 심층면담과 참여관찰을 통해 수집하였으며, 참여 경험을 통한 효과에 대해 깊이 있는 의미를 도출하고자 현상학적 연구방법을 이용하였다. 본 연구의 분석 결과 프로그램 참여자가 경험한 라인댄스 프로그램의 효과로 신체적 효과 (생리적 변화, 소화 기능 향상, 수면의 질 향상, 신체의 유연성 증가, 인지 기능 향상), 심리적 효과 (재미와 즐거움, 활력, 평온, 자신감 향상, 자기만족), 사회적 효과 (가족 분위기 향상, 친밀도의 향상), 라인댄스 지속 효과(지속적 연습 및 스스로의 복습, 라인댄스 재미 발견, 참여의 지속 원함, 수업의 기대)로 범주화하였다. 마지막으로, 참여자들은 라인댄스에 참여하면서 서로에게 필요한 정보 공유 및 습득하였고, 프로그램에 참여하는 다른 유방암 환자들과 공감 하고 서로 위안이 되었다고 하였으며, 이로 인한 시너지 효과를 느끼는 것으로 나타났다. 따라서 그룹으로 이루어지는 라인댄스 프로그램은 향후 유방암 생존자들에게 적용될 수 있는 매우 안전하고 효과적인 운동프로그램 중 하나로 사료되어 진다.