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Use of Flattening Filter Free Photon Beams for Off-axis Targets in Conformal Arc Stereotactic Body Radiation Therapy

  • Smith, Ashley;Kim, Siyong;Serago, Christopher;Hintenlang, Kathleen;Ko, Stephen;Vallow, Laura;Peterson, Jennifer;Hintenlang, David;Heckman, Michael;Buskirk, Steven
    • Progress in Medical Physics
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    • v.25 no.4
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    • pp.288-297
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    • 2014
  • Dynamic conformal arc therapy (DCAT) and flattening-filter-free (FFF) beams are commonly adopted for efficient conformal dose delivery in stereotactic body radiation therapy (SBRT). Off-axis geometry (OAG) may be necessary to obtain full gantry rotation without collision, which has been shown to be beneficial for peripheral targets using flattened beams. In this study dose distributions in OAG using FFF were evaluated and the effect of mechanical rotation induced uncertainty was investigated. For the lateral target, OAG evaluation, sphere targets (2, 4, and 6 cm diameter) were placed at three locations (central axis, 3 cm off-axis, and 6 cm off-axis) in a representative patient CT set. For each target, DCAT plans under the same objective were obtained for 6X, 6FFF, 10X, and 10FFF. The parameters used to evaluate the quality of the plans were homogeneity index (HI), conformality indices (CI), and beam on time (BOT). Next, the mechanical rotation induced uncertainty was evaluated using five SBRT patient plans that were randomly selected from a group of patients with laterally located tumors. For each of the five cases, a plan was generated using OAG and CAG with the same prescription and coverage. Each was replanned to account for one degree collimator/couch rotation errors during delivery. Prescription isodose coverage, CI, and lung dose were evaluated. HI and CI values for the lateral target, OAG evaluation were similar for flattened and unflattened beams; however, 6FFF provided slightly better values than 10FFF in OAG. For all plans the HI and CI were acceptable with the maximum difference between flattened and unflattend beams being 0.1. FFF beams showed better conformality than flattened beams for low doses and small targets. Variation due to rotational error for isodose coverage, CI, and lung dose was generally smaller for CAG compared to OAG, with some of these comparisons reaching statistical significance. However, the variations in dose distributions for either treatment technique were small and may not be clinically significant. FFF beams showed acceptable dose distributions in OAG. Although 10FFF provides more dramatic BOT reduction, it generally provides less favorable dosimetric indices compared to 6FFF in OAG. Mechanical uncertainty in collimator and couch rotation had an increased effect for OAG compared to CAG; however, the variations in dose distributions for either treatment technique were minimal.

Single-Camera Micro-Stereo 4D-PTV (단일카메라 마이크로 스테레오 4D-PTV)

  • Doh, Deog-Hee;Cho, Young-Beom;Lee, Jae-Min;Kim, Dong-Hyuk;Jo, Hyo-Jae
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.12
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    • pp.1087-1092
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    • 2010
  • A micro 3D-PTV system has been constructed using a single camera system. Two viewing holes were created behind the object lens of the microscopic system to construct a stereoscopic viewing image. A hybrid recursive PTV algorithm was used. A concept of epipolar line was adopted to eliminate many spurious candidates. Three-dimensional velocity vector fields were obtained by calculating the three-dimensional displacements of particles that were identified as being identical. The system consists of a laser light source (Ar-ion, 500 mW), one high-definition camera ($1028{\times}1024$ pixels, 500 fps), a circular plate with two viewing holes, and a host computer. The performance of the developed algorithm was tested using artificial images. The characteristic of the vector recovery ratio was investigated for the particle numbers. A micro backward-facing step channel ($H{\times}h{\times}W:\;36{\mu}m{\times}70{\mu}m{\times}3000{\mu}m$) was measured using the developed measurement system. The results were in good qualitative agreement with other results.

Seismic Evaluation of Steel Moment Frame Buildings based on Different Response Modification Factors and Fundamental Periods (반응수정계수와 주기의 영향에 대한 철골모멘트저항골조 건물의 내진성능평가)

  • Shin, Ji-Wook;Lee, Ki-Hak;Lee, Do-Hyung
    • Journal of the Earthquake Engineering Society of Korea
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    • v.12 no.5
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    • pp.47-56
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    • 2008
  • This study was performed to evaluate the effect of Response modification factors (R-factor) in 3-, 9- and 20- story steel Moment Resisting Frame (MRF) buildings. Each structure was designed using a R-factor of 8, as tabulated in the 2000 International Building Code provision (IBC 2000) and Korea Building Code (KBC) 2008. In order to evaluate the maximum and minimum performance expected for such structures, an upper bound and lower bound design were adopted for each model. Next, each analytical model was designed using different R-factors (8, 9, 10, 11, 12) and four different structural periods with the original fundamental period. For a detailed case study, a total of 150 analytical models were subjected to 20 ground motions representing a hazard level with a 2% probability of being exceeded in 50 years. In order to evaluate the performance of the structures, static push-over and non-linear time history analysis (NTHA) were performed, and displacement ductility demand was investigated to consider the ductility capacity of the structures. The results show that the dynamic behaviors for the 3- and 9-story buildings are relatively stable and conservative, while the 20-story buildings show a large displacement ductility demand due to dynamic instability factors. (e.g. P-delta effect and high mode effect)

The Constitutional Ideas in the 『Huangdi Neijing』 (『황제내경(黃帝內經)』의 체질론(體質論))

  • Choi, Seung-hoon
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.2
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    • pp.15-28
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    • 1998
  • One's constitution is formed congenitally and is also acquired, and is relatively stable in its individually manifested function, structure and temperament. It has characteristics of universality, complexity, generality and continuity. It is also manifested in physiological responses and expresses pathologic tendencies including susceptibility. Attempts at understanding constitution has had a long history throughout the world. In Oriental Medicine, the constitution had been acknowledged from the "Huangdi Neijing", which has been a bible in Oriental Medicine for about two thousand years. In many aspects, the "Huangdi Neijing" provides the basis for both basic and practical fields. In order to derive the ideal structure from the "Huangdi Neijing" to Lee Je-ma's(Lee Jayma's) Sasang Constitutional ideas, which can strengthen the understanding of ideal core of Oriental Medicine's constitutional characteristics, the author launched his analysis of the constitutional understandings in the "Huangdi Neijing" as a first step and came to the following: 1. The constitutional understanding in the "Huangdi Neijing" was done both via the physiological responses to heat, pain and acupuncture treatment and the pathologic tendencies via body structure, strength, body heat, courage and obesity. 2. It was recognized that the constitution was formed congenitally and also acquired factors like living conditions including food customs, residents and geographical conditions were explained in detailed. 3. The constitutional typology was suggested both by the general and systematic criterion according to the Yin-yang and the Five phase theories and by single criterion such as obesity, courage and the response to acupuncture treatment. 4. As diagnosis is related to the constitution, courage was adopted for the disease caused by emotions, obesity was for its manifestations of qi and blood, the quantities of qi-blood and Yin-yang in the typology by the Yin-yang and Five phase theories were suggested. 5. In the case of obesity, Yin-yang and Five phase theory, treatment according to the constitutional ideas was mentioned, and their goals were concluded as "being the balancing between Yin and Yang" which means the Yin-yang theory is more practical than the Five phase theory in Oriental Constitutional Medical field. According to the above understandings, the author would like to suggest that the constitutional ideas in the "Huangdi Neijing" based on the Yin-yang theory blossomed via the practical spirit of Zhang Zhong-jing's "Shanghanlun" and at last from Lee Je-ma's(Lee Jayma's) Sasang Constitutional Medicine which realized "the balancing between Yin and yang" through the practical applications of herbal treatments.

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Cancer Registration in Korea: The Present and Furtherance (암 등록사업의 현황과 추진방향)

  • Ahn, Yoon-Ok
    • Journal of Preventive Medicine and Public Health
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    • v.40 no.4
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    • pp.265-272
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    • 2007
  • It was not until 1975 that cancer registration was initiated in Korea; voluntary registration of cancer patients of training hospitals throughout the country began under the auspices of the Korean Cancer Society(KCS). However, an official cancer registration, the Korea Central Cancer Registry(KCCR), began on July 1st, 1980. Forty-five training and two non-training hospitals throughout the country initiated registration of patients in whom neoplasms had been found. Data related to case information specified are to be sent to the KCCR at the National Medical Center(it moved at National Cancer Center in 2000). The initial cancer registration of KCS was merged to the KCCR in 1980. Although the KCCR covers most all the large training hospitals in Korea, it cannot provide incidence data. It is, however, the only of its kind in the world, being neither hospital nor population based. The first population based cancer registry(PBCR) was launched in a small county, Kangwha(it has around 80,000 inhabitants), by Yonsei University Medical College in 1983. All data were collected by active methods, and incidence statistics for 1986-1992 appeared in Vol VII of the CI5. Another PBCR, Seoul Cancer Registry(SCR), started in 1991. It was supported by a civilian foundation, the Korean Foundation for Cancer Research. The basic idea of case registration of SCR was the incorporation of KCCR data to PBCR, e. g. dual sources of case registration, i.e., from the KCCR and also including cases diagnosed in small hospitals and other medical facilities. Assessing completeness and validity of case registration of SCR, the program and methodology used by the SCR was later extended to other large cities and areas in Korea, and the PBCR in each area was established. Cancer incidence statistics of Seoul for 1993-1997, Busan for 1996-1997, and Daegu for 1997-1998, as well as Kangwha for 1993-1997, appeared eventually in Vol VIII of the CI5. The Korean or 'pillar' model for a PBCR is a new one. The KCCR data file is a reliable basis, as a pillar, for a PBCR in each area. The main framework of the model for such a registry is the incorporation of a KCCR data file with data from additionally surveyed cases; the data related to cancer deaths, medical insurance claims, and visit-and surveillance of non-KCCR medical facilities. Cancer registration has been adopted as a national cancer control program by Korean government in 2004 as the Anti-Cancer Act was enacted. Since then, some officers have tried to launch a nation-wide PBCR covering whole country. In the meantime, however, cancer registration was interrupted and discontinued for years due to the Privacy Protection Law, which was solved by an amendment of the Anti-Cancer Act in 2006. It would be premature to establish the nation-wide PBCR in Korea. Instead, continuous efforts to improve the completeness of registration of the KCCR, to progress existing PBCRs, and to expand PBCRs over other areas are still to be devoted. The nation-wide PBCR in Korea will be established eventually with summation of the PBCRs of the Korean model.

Study of an Applicability of an Urban Design Method Using Artificial Life Theory (인공생명이론을 이용한 도시설계방법의 적용 가능성에 대한 연구)

  • Lim, Myunggu;Kim, Kyoontai
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.4
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    • pp.93-101
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    • 2018
  • A city is like a living organism that is born, grows and become extinct within an ecosystem. In recent years, more and more cities have been planned by designers rather than spontaneously growing over time. This planning means that if a city is not appropriately designed at the beginning, it is very hard to fix or adjust it later. A poor urban design inconveniences many people, and forces them to adjust to it. For this reason, it is important to design a city as optimally as possible at the design phase. One of the reasons why a city is not designed optimally is complexity. Previous urban design methods have attempted to resolve the complexity by using a top-down problem-solving method based on the experience and knowledge of the urban planner. However, such an approach does not have the organic characteristics of a bottom-up problem-solving method of an artificial life, based on the creation principle of the ecosystem. Therefore, in this study the general principle of artificial life, which can provide a solution to the bigger problems that accumulate as a result of the solutions to small units of problems, is adopted. This enables us to draw various urban design alternatives, and it proves that the alternatives, despite being drawn through a limited modeling method, have almost no differences from those designed by an expert, and its possibilities of future development has also been verified.

The effect of empathy training game on the children's prosocial behavior (게임을 활용한 공감훈련이 초등학생의 친사회적 행동 증진에 미치는 영향)

  • Kim, Hyung-Hoe
    • The Korean Journal of Elementary Counseling
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    • v.4 no.1
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    • pp.263-284
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    • 2005
  • The purpose of this study was to examine the effect of game-centered empathy training on the prosocial behaviors of elementary schoolers in a bid to suggest how their prosocial behaviors could be boosted. The research questions were posed as below: 1. Does game-based empathy training improve the overall empathy of school children? 2. Does game-based empathy training have a better effect on the cognitive empathy of school children or their emotional empathy? 3. Does game-based empathy training enhance the prosocial behaviors of school children? The subjects in this study were 62 children in their fourth year of D elementary school in Eumseong-gun, north Chungcheong province. They were divided into an experimental group and a control group, and a survey was conducted before and after the experimental group under-went empathy training for about six weeks. The instrument used in this study was David(1980)'s Interpersonal Reactivity Index adopted by Park Sung-hee(1996) to suit school children. Another instrument was Park Sung-hee (1997)'s inventory to assess the prosocial behaviors of children. The collected data were analyzed by SPSS 10.0 for Windows program, and reliability analysis and t-test were employed. The findings of the study were as follows: First, as for the effects of the game-based empathy training on the overall empathy of the elementary school youngsters that included both emotional and cognitive empathy, both groups got lower scores in posttest than in pretest. The experiment produced unexpected results, as the experimental group got significantly lower scores. This fact indicated that the game-based empathy training was ineffective. Second, the game-centered empathy training didn't exercise any influences on their cognitive and emotional empathy. The experiment had a reverse impact on the cognitive and emotional empathy of the experimental group, which implied that the training served as a factor to deteriorate the two types of empathy, and the hypothesis posed in this study was rejected. Therefore, which type of empathy could make a better progress by being exposed to the training couldn't definitely be determined. Third, the game-based empathy training didn't serve to Improve the prosocial behaviors of the elementary schoolers. There was no change in the experimental group, and this fact signified that there's something wrong with the attempt to develop school children's empathy to step up their prosocial behaviors. Based on the above-mentioned findings, the following conclusion was reached: First, the game-centered empathy training had no effects on boosting the overall empathy of the school children. Second, the game-centered empathy training couldn't be said to be effective in improving either cognitive empathy or emotional one. From a viewpoint of relativity, that could be said to affect emotional empathy more than cognitive one. Third, the game-based empathy training wasn't effective in improving prosocial behaviors. Rather, that resulted in interrupting the promotion of prosocial behaviors.

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A Study on the Enhancement of Maritime Education and Training to cope with IMO Member-state Audit Scheme (IMO 회원국 감사제도 대응을 위한 해기교육 강화방안에 관한 연구)

  • Lee, Yun-Cheol;Park, Sung-Ho
    • Journal of Navigation and Port Research
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    • v.37 no.2
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    • pp.203-210
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    • 2013
  • In spite of adoption of various IMO Conventions over the past, the reason why large vessel accidents related to human life and marine environment occur is that the IMO Conventions are not effectively implemented due to contravention of the conventions by flag states. In particular, the implementation of the conventions are not well being performed because some flag states having weak genuine link between them and vessels haven't set up proper personal and structural organizations in charge of maritime safety and marine environment protection. From this background, IMO Resolution A.946(23) on the voluntary IMO Member-state Audit Scheme was adopted at the 23rd Assembly in Nov. 2003 and the Scheme is expected to be executed compulsorily in 2015 through the adoption of the IMO Resolution A.1018(26) in Nov. 2009. Accordingly, this study examined outline of the IMO Member-state Audit Scheme and the Code for the Implementation of Mandatory IMO Instruments used for the audit standards of this scheme. In addition, this study reviewed the member-states' obligations and responsibilities according to the compulsory implementation of the member-state audit scheme in 2015. Based on this, this study suggested the enhancement measures for maritime education and training of maritime education institutions of the Republic of Korea to cope positively with compulsory implementation of the IMO Member-state Audit Scheme.

Development of the HEMP Generation, Propagation Analysis, and Optimal Shelter Design Tool (고 고도 전자기파(HEMP) 발생과 전파해석 및 방호실 최적 설계 Tool 개발)

  • Kim, Dong Il;Min, Gyeong Chan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.10
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    • pp.2331-2338
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    • 2014
  • The HEMP threat may have acquired new, and urgent, relevance as the proliferation of nuclear weapons and missile technology accelerates of the North Korea, for example, is assessed as already having developed few atomic weapons, and is on the verge of North Korea already has missiles capable of delivering a nuclear warhead against South Korea. ITU K.78, K81 and IEC recommended its counter-measuring for the industrial facilities with navigation and sailing facilities in order to obviate the all of processor equipped system malfunctions from the EMP/HEMP but its simulation must only be done by the computer simulation which had studied on the 1960-1990 years USA/AFWL papers. This result has a significant activities to the South Korea being under the North Korea threat because all of HEMP related products was strongly limited for export. The HEMP cord which was developed newly by the KTI including the HEMP generation & propagation analysis, optimal shelter design tool, essential EM energy attenuation in multi-layered various soils and rocks and HEMP filter design tool. Especially, the least square fitting method was adopted to analysis for the EM energy attenuation in the soils and rocks because it has a various characteristics based on the many times field test reports.

A Study on the Critical Factors for Successful AIS Implementation (회계정보시스템의 성공적 도입을 위한 요인분석)

  • Ha, Dae-Yong;Oh, Sang-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.7 no.6
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    • pp.1364-1370
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    • 2006
  • Recently, Adopting Accounting Information Systems(AIS) has spread rapidly for efficient and rational making decision in the business organization. There are many types of AIS. These are from simple package to integrated packages which are including HR, Product, Sales and Distribute. In case of big enterprises, ERP systems have been implemented and attention is now being directed as to AIS module. AIS module is not easy to change its form, therefore this module need to be considered enough when it comes to the corporations. However there we few standard fer this module as a successful information systems. This study analyze critical factors of certain companies when the companies were implementing AIS and based on this analysis, this study suggest a framework for successful implementation of AIS Using Case Study. 42 AIS adopted companies are surveyed and their factors' correlations are analyzed by mean analysis and factor analysis in this study. As a result of this study, when a company adopt AIS, criteria or particularities for the adoption are more important than environment of the company. Thus, it is significant to empirically prove previous studies' factors relation and importance relations for successful AIS implementation through empirical method in this study.

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