• 제목/요약/키워드: baseline risk

검색결과 428건 처리시간 0.029초

Weight Gain and Alcohol Drinking Associations with Breast Cancer Risk in Japanese Postmenopausal Women - Results from the Japan Collaborative Cohort (JACC) Study

  • Nitta, Junichi;Nojima, Masanori;Ohnishi, Hirofumi;Mori, Mitsuru;Wakai, Kenji;Suzuki, Sadao;Fujino, Yoshihisa;Lin, Yingsong;Tamakoshi, Koji;Tamakoshi, Akiko
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1437-1443
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    • 2016
  • Background: We investigated four factors, height, weight gain since age 20, physical activity, and alcohol drinking, for associations with risk of breast cancer (BC) according to menopausal status, using the latest data of the Japan Collaborative Cohort Study (JACC Study). Materials and Methods: We confined the analysis to 24 areas available of cancer incidence information, excluding women with a previous diagnosis of BC. Baseline data were collected from 38,610 (9,367 premenopausal, and 29,243 postmenopausal) women during 1988 and 1990. The study subjects were followed-up at the end of 2009, and 273 (84 premenopausal, and 189 postmenopausal) cases of BC were newly diagnosed in 501,907 person-years. The Cox model was used to estimate a hazards ratio (HR) and its 95% confidence interval (CI) of BC risk. Results: As a result of the multivariate analysis adjusting for age at baseline survey, age at menarche, number of live births, and, age at first delivery, weight gain since age 20 of 6.7 kg-9.9 kg, and ${\geq}10.0kg$ were significantly associated with increased risk for postmenopausal BC (HR=2.48, 95% CI 1.40-4.41, and, HR=2.94, 95% CI 1.84-4.70, respectively). Significantly increased trend of BC risk was also observed in weight gain since age 20 (p for trend, p<0.001). Amount of ethanol intake per day${\geq}15.0g$ was significantly associated with increased risk for postmenopausal BC in the multivariable-adjusted analysis (HR=2.74, 95% CI 1.32-5.70). Conclusions: Higher weight gain in adulthood and larger amounts of ethanol intake were significantly associated with increased risk of BC in Japanese postmenopausal women. None of the investigated factors were significantly associated with BC risk in Japanese premenopausal women.

한국인의 실내 라돈-222 자핵종 피폭으로 인한 초과 폐암위험 (Evaluation of Excess Lung Cancer Risk in Korean due to Indoor Exposure to Natural $^{222}Rn$ Progenies)

  • 장시영;하정우;이병헌
    • Journal of Radiation Protection and Research
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    • 제17권1호
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    • pp.57-70
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    • 1992
  • 실내 라돈-222 자핵종의 농도에 피폭되므로서 유발될 수 있는 한국인의 초과 폐암위험을 방사선피폭의 확율론적 위험예측 모형을 이용하여 정량적으로 평가하였다. 1989년 기준 표준 생명표와 사망원인 통계연보 자료로부터 유도한 한국인의 폐암 사망률은 남, 여별로 각각 $22.4/10^5-$년 및 $9.5^/10^5-$년으로 추정 되었다. 이 폐암 사망율을 근거로 수학적으로 예상한 한 모든 사망원인하의 기저 폐암사망위험은 남, 여별로 각각 0.047(4.7%) 및 0.019(1.9%)로 1984년도 미국의 0.067(6.7%) 및 0.025(2.5%)보다 낮았다. 방사선 피폭의 확률론적 수정 상대위험 예측모형을 사용하여 예상한 한국인의 라돈자핵종 피폭당의 초과 폐암위험 계수는 남자 : 0.022/WLM, 여자 : 0.009/WLM 및 평균 : 0.017/WLM로 나타났으며 이로부터 추정한 한국인의 평균 수명중 라돈자핵종 피폭유발 초과 폐암의 사망빈도는 $230/10^6$인-WLM으로 최근 외국의 관련연구에서 보고한 $120{\sim}450/10^6-WLM$의 거의 중간치(median)정도에 해당하는 것으로 평가되었다.

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응급구조학과 학생들의 교통 및 재난에 대한 위험인식 및 안전실천에 관한 연구 (Risk perception and safety practice of paramedic students)

  • 이경열
    • 한국응급구조학회지
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    • 제20권1호
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    • pp.71-82
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    • 2016
  • Purpose: This research aimed to provide baseline data for undergraduate safety education by evaluating paramedic student risk perception and safety practice behavior regarding transport and disaster-related accidents. Methods: A total of 367 paramedic students at three different universities were surveyed using questionnaires. Risk perception questions about hazard, feeling of dread, and uncontrollable factors regarding seven items in transport and disasters were asked on a 7-point scale. Safety practice behavior consisted of 14 transport-related questions and 12 disaster-related questions in 4-point scale. All data were analyzed using SPSS Window 21.0. Results: Of 367 surveyed, 54.8% (201) were females, and 28.9% (106) were freshmen. In risk perception, 'drunk driving' in transport was the highest on average obtaining 6.49 points for hazard and 5.12 points for the feeling of dread. In disasters, 'war' recorded the highest average with 6.61 points for hazard and 5.71 points for the feeling of dread. In safety practice behavior regarding transport and disasters, a higher awareness of the need for safety education correlated with a significantly higher the rate of safety practice behavior (p <.001 respectively). Conclusion: The results indicate that undergraduates have inadequate perception of risk in emergencies. Safety education programs are needed to raise awareness of risks and to increase the safety practice rate.

동기강화 프로그램이 노년기 여성의 건강행위, 심혈관질환 위험요인 및 기능적 건강상태에 미치는 영향 (Effects of Motivation-Enhancing Program on Health Behaviors, Cardiovascular Risk factors, and Functional status for Institutionalized Elderly Women)

  • 송라윤;전경자;노유자;김춘길
    • 대한간호학회지
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    • 제31권5호
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    • pp.858-870
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    • 2001
  • Purpose: This study was to compare changes in health behaviors, motivational factors, cardiovascular risk factors, and functional status (SIP) after implementing the 6-month motivation-enhancing program to institutionalized elderly women. Methods: Sixty-four elderly women participated. Face to face interviews with blood sampling and anthropometric assessment were conducted at the pretest, 10 weeks and 6 months during the program. Results: 1. The program participants showed significantly better health behaviors over 6 months. The mean motivational level was also significantly improved, especially for perceived benefits, perceived barriers, and emotional salience. 2. The mean of cardiovascular risk factors for the participants was 21.8 at the level of low to moderate risk. After completing the program, total risk score was significantly decreased to 18.7 at 10 weeks, and further to 17.7 at 6 months. A significant reduction was also found in HDL and LDL-cholesterol levels, blood pressure, obesity, inactivity, and stress. 3. The functional status (SIP) was 11% at the baseline and significantly changed in positive direction at 10 weeks(M=9.3) and at 6 month(M=6.3). The significant improvement was also found in physical and psychosocial dimensions and sleep/rest dimension. Conclusion: The motivation enhancing program was effective to reduce cardiovascular risks and to improve the functional status of institutionalized elderly women by motivating them to perform better health behaviors.

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사회경제적 요인에 따른 지역사회 저소득층 중년여성의 심혈관질환 위험요인 차이 (Cardiovascular Disease Risk according to Socioeconomic Factors among Low-income Midlife Women)

  • 함옥경;김봉정;이영아
    • 한국보건간호학회지
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    • 제22권1호
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    • pp.27-38
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    • 2008
  • Purpose: To determine the degree of cardiovascular disease risk according to socioeconomic factors among midlife women in the community and thereby provide baseline data for the development of health promotion programs. Method: A total of 200 women participated in health screenings and a health survey. The survey was performed in November and December, 2006. The survey instruments included socioeconomic factors, health behavior (smoking and exercise), and family history. Biophysical measurement included BMI and blood pressure. Blood samples were drawn for glucose and total cholesterol tests. Results: The mean age was 52.5 years, 34.0% had received education less than 6 years, 70.0% earned a monthly income of less than \1,500,000, and 61.5% were homemakers. Cardiovascular disease risk was significantly different by age (BMI, systolic BP, and exercise), education (systolic BP), monthly income (T. cholesterol), marital status (smoking), and occupation (exercise). Most women had 2 or 3 cardiovascular disease risks. Older age, lower education, and lower income were significantly associated with increased cardiovascular disease risk. Conclusion: Efforts should be made to decrease the number and severity of cardiovascular disease risk factors for midlife women in the community by developing health promotion programs targeting to modify their cardiovascular disease risk factors.

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A Longitudinal Investigation of the Moderating Effect of Social Support on Job Strain Developing Non-Specific Neck Pain in Office Workers

  • Jun, Deokhoon
    • The Journal of Korean Physical Therapy
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    • 제31권4호
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    • pp.254-259
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    • 2019
  • Purpose: This study examined the interactions between the job strain and social support in the workplace on the development of workrelated neck pain in office workers. Methods: The participants included 62 office workers without neck pain over the last twelve months. A battery of measures evaluating the potential workplace risk factors in office settings were conducted at the baseline, and at the 12 month incidence of work-related neck pain was reported via monthly questionnaires. Survival analysis evaluated the interaction effect between job strain and social support on the development of work-related neck pain. Results: The incidence of work-related neck pain was 1.91 (95% CI: 1.06 - 3.45) per 100 person months. The interaction effect between job strain and social support found that job strain may increase the risk of developing new work-related neck pain when lower social support existed in the workplace. On the other hand, the adverse effects of job strain on the development of neck pain were not significant when workers had higher social support from their colleagues and supervisors. Conclusion: An investigation of the moderating effects of risk factors on neck pain might reveal the unexplained relationship between the risk factors for the development of neck pain in office workers. Therefore, the interest in prevention plans and treatments should involve a comprehensive understanding of the risk factors at workplace.

발주자를 위한 프로젝트 성과측정기준선 설정 방안에 관한 연구 (A study on the Project Performance Measurement Baseline for Clients)

  • 고대준;최은아;박동진;이상범
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2008년도 정기학술발표대회 논문집
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    • pp.513-516
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    • 2008
  • 건설프로젝트는 많은 불확정 요소로 인해 다양한 리스크를 가지고 있기 때문에 프로젝트 진행 과정에서 반복적인 성과측정은 중요하다. 그러나 현재 건설프로젝트에서 성과측정은 시공사 중심의 성과측정 및 성과관리가 이루어 져서 프로젝트의 진행상황에 따른 발주자의 능동적인 프로젝트 관리가 어렵다. 이에 본 연구에서는 실제 실행된 공공 아파트 건설공사의 공기 비용 데이터를 타입별로 분류하여 회귀분석을 실시하고 타입별 회귀식을 도출, 발주자 중심의 작업분류체계를 설정하고 이를 활용하여 이를 발주자 중심의 성과측정기준선을 제안방안을 제시하고자 한다.

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Effects of Calcium and Vitamin D Supplementation on Bone Mineral Density and Biochemical Markers in Osteoporotic Postmenopausal Women

  • Kim, Jeong, Seon;Kim, Joo-Hak
    • Nutritional Sciences
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    • 제9권1호
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    • pp.42-47
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    • 2006
  • It has been reported that taking a proper amount of calcium and vitamin D helps to increase bone mineral density (BMD) and is effective in decreasing the risk of osteoporosis. This study investigated the supplementary effects of calcium and vitamin D on postmenopausal women who had osteoporosis and used calcium and vitamin D supplements. The study subjects consisted of osteoporotic postmenopausal women who were recruited from the Department of Orthopedics in a university-affiliated hospital. Sixty-seven study subjects were orally administrated 1,000 mg of calcium (calcium carbonate) and 2.5 mg of active vitamin D (1-$\alpha$ hydroxyvitamin D) (cholecalciferol 250 IU) twice a day for a year and a half. BMD and biochemical markers were evaluated and repeated every six months. One year after the intervention test, the bone mineral density of the lumbar spine was significantly increased as compared to the baseline. Six months after supplement administration, the level of serum alkaline phosphatase began to decrease, and afterwards a significant difference was maintained Concentration of 1, 25-dihydroxy-vitamin D at 1.5 years was higher than that of the baseline. In comparison with that of the baseline, the level of urinary hydroxyproline in the study subjects over six months was significantly decreased This study continued that effects such as BMD improvement and changes in biochemical markers appeared at least one year after administration of supplements.

Associations between Sleep and Work-Related Cognitive and Emotional Functioning in Police Employees

  • Sorengaard, Torhild Anita;Olsen, Alexander;Langvik, Eva;Saksvik-Lehouillier, Ingvild
    • Safety and Health at Work
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    • 제12권3호
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    • pp.359-364
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    • 2021
  • Aim: We aimed to examine the cross-sectional and longitudinal associations between sleep and work-related impaired cognitive and emotional functioning in police employees. Methods: This study included 410 participants (52% men) employed in a police district in Norway at baseline, of which 50% also participated in the study at 6 months later follow-up. The questionnaires included items measuring work schedule, sleep length, insomnia, as well as impaired cognitive and emotional functioning at work. Results: The results showed that insomnia was related to impaired work-related emotional functioning measured at baseline, and to impaired cognitive functioning measured at both baseline and follow-up. Sleep length and rotating shift work were not associated with future decline in cognitive or emotional functioning. Conclusion: Our study indicates that the relationship between insomnia and emotional functioning at work may be transient, whereas insomnia can be related to both immediate and future impaired cognitive functioning. Replication of the findings in larger samples is advised. The findings call for an emphasis on the prevention and treatment of sleep problems among police employees as a mean of maintaining and improving cognitive and emotional functioning at work, and thereby reducing the risk for impaired performance and negative health and safety outcomes.

Utilization of SAR Data for Baseline Environmental Studies of Central Cebu Island, Philippines ? Phase 1

  • Lituanas, Michael B.;Salvador, Jerry Hervacio G.
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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    • pp.981-983
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    • 2003
  • The Remote Sensing Group of the Mines and Geosciences Bureau (MGB) has acquired SAR data of the Central Cebu Island for its research study area. The MGB is one of the proponent of DOST-NASA PACRIM II Project, which is composed of eleven (11) agencies and institutions in the Philippines, that focuses on the scientific application of radar data with the theme on hazard and natural resources management. The PACRIM II Project, being done on three-year term, is slated for completion in the year 2004. The main thrust of the project study of the MGB is the baseline environmental monitoring studies, on which the data are to be fused with some other available data from LandSAT and photogrammetry. The generated data is part of the information for the update of thematic mapping being done. The 12 ${\times}$ 60 km swath AirSAR data covers the Central Cebu Island. The highlights of conducting this research project are: Extent of Watershed Basin boundaries - identification of the tributaries that drain water supply to the metropolitan area; Monitoring of the mountain highways - identification of landslide risk prone sites as part of natural hazard monitoring on a national highway that cuts along the mountainous areas; and Coastline change assessment - monitoring the coastline activities relative to the rapid urbanization and exposure as part of coastal management. The Phase 1 of this report discusses the fusion with the ArcView generated data as baseline studies on the monitoring activities.

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