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SIFamide and SIFamide Receptor Define a Novel Neuropeptide Signaling to Promote Sleep in Drosophila

  • Park, Sangjin;Sonn, Jun Young;Oh, Yangkyun;Lim, Chunghun;Choe, Joonho
    • Molecules and Cells
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    • v.37 no.4
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    • pp.295-301
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    • 2014
  • SIFamide receptor (SIFR) is a Drosophila G protein-coupled receptor for the neuropeptide SIFamide (SIFa). Although the sequence and spatial expression of SIFa are evolutionarily conserved among insect species, the physiological function of SIFa/SIFR signaling remains elusive. Here, we provide genetic evidence that SIFa and SIFR promote sleep in Drosophila. Either genetic ablation of SIFa-expressing neurons in the pars intercerebralis (PI) or pan-neuronal depletion of SIFa expression shortened baseline sleep and reduced sleep-bout length, suggesting that it caused sleep fragmentation. Consistently, RNA interference-mediated knockdown of SIFR expression caused short sleep phenotypes as observed in SIFa-ablated or depleted flies. Using a panel of neuron-specific Gal4 drivers, we further mapped SIFR effects to subsets of PI neurons. Taken together, these results reveal a novel physiological role of the neuropeptide SIFa/SIFR pathway to regulate sleep through sleep-promoting neural circuits in the PI of adult fly brains.

An Effective Approach Using Sentence Symbols to Identify Maximal-Length Noun Phrase in Chinese (문장부호를 사용한 효과적인 중국어 최장명사구 식별기법)

  • Bai Xue-Mei;Li Jin-Ji;Jin Mei-Xun;Cheng You-Jin;Lee Jong-Hyeok
    • Proceedings of the Korean Information Science Society Conference
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    • 2005.07b
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    • pp.454-456
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    • 2005
  • 일반적으로 중국어의 명사구는 최단명사구, 기본명사구 최장명사구로 분류된다. 최장명사구에 대한 정확한 식별은 문장의 전체적인 구조를 파악하고 문장의 정확한 지배용언을 찾아내는데 중요한 역할을 한다. 본 논문에서는 특성에 따라 5개의 클래스로 세분화된 문장부호를 학습자질로 사용하여 최장명사구 자동식별을 진행한다. 제안된 기법은 평균길이가 4인 최장명사구의 식별실험에서 기본모델(baseline)보다 $4.5\%$ 향상된 평균 $85.1\%$의 우수한 F-measure 성능을 보인다.

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Uranium Enrichment Reduction in the Prototype Gen-IV Sodium-Cooled Fast Reactor (PGSFR) with PBO Reflector

  • Kim, Chihyung;Hartanto, Donny;Kim, Yonghee
    • Nuclear Engineering and Technology
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    • v.48 no.2
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    • pp.351-359
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    • 2016
  • The Korean Prototype Gen-IV sodium-cooled fast reactor (PGSFR) is supposed to be loaded with a relatively-costly low-enriched U fuel, while its envisaged transuranic fuels are not available for transmutation. In this work, the U-enrichment reduction by improving the neutron economy is pursued to save the fuel cost. To improve the neutron economy of the core, a new reflector material, PbO, has been introduced to replace the conventional HT9 reflector in the current PGSFR core. Two types of PbO reflectors are considered: one is the conventional pin-type and the other one is an inverted configuration. The inverted PbO reflector design is intended to maximize the PbO volume fraction in the reflector assembly. In addition, the core radial configuration is also modified to maximize the performance of the PbO reflector. For the baseline PGSFR core with several reflector options, the U enrichment requirement has been analyzed and the fuel depletion analysis is performed to derive the equilibrium cycle parameters. The linear reactivity model is used to determine the equilibrium cycle performances of the core. Impacts of the new PbO reflectors are characterized in terms of the cycle length, neutron leakage, radial power distribution, and operational fuel cost.

Shape Design of Construction Equipment Tailpipe for Noise Reduction and Engine Room Cooling (소음 및 엔진룸 냉각개선을 위한 건설기계테일파이프의 형상설계)

  • Kim, Seong-Jae;Yang, Ji-Hae;Kim, Nag-In;Kim, Jou-Sik
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.11a
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    • pp.737-740
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    • 2004
  • The interior noise reduction of construction equipment is concerned for improving the driver comfort in this study. From the baseline test, the exhaust noise gives a big contribution to the interior noise of construction equipment. And the detail noise contribution analysis of the exhaust system, the tail pipe, which is for ventilation an engine room hot air to outside, amplify the exhaust noise around operating engine RPM associated with tail pipe structural and cavity resonances. To remove the noise amplifying effects, the tail pipe has to be shorted its length. Even the noise can be attenuated the ventilation flux when using the redesigned tail pipe is reduced than the original one. Thus, a shape change of the tail pipe is additionally needed for increasing the ventilation flux and attenuating the exhaust noise using CFD technique. The CFD results of the tail pipe give a meaning full information what obstructs the ventilation flex in the current design and how changes the tail pipe.

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Accuracy of periodontal probe visibility in the assessment of gingival thickness

  • Kim, Young-Sung;Park, Ji-Sun;Jang, Young-Hun;Son, Jung-Hun;Kim, Won-Kyung;Lee, Young-Kyoo;Kim, Su-Hwan
    • Journal of Periodontal and Implant Science
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    • v.51 no.1
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    • pp.30-39
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    • 2021
  • Purpose: The present study was undertaken to examine whether periodontal probe visibility (PV) accurately reflects gingival thickness (GT) and to identify factors affecting PV using cluster and multivariate analyses. Methods: The clinical characteristics of the maxillary central incisors (n=90 subjects) were examined. Clinical photographs, sex, PV, probing depth, gingival width, papilla height, GT as measured with an ultrasonic device, and the ratio of crown width to crown length were recorded. Multivariate analysis, using multinomial baseline-category logistic regression, was used to identify factors predictive of PV. Cluster analysis was used to identify gingival biotypes. Results: In the multivariate analysis, sex was the only significant predictor of PV (odds ratio, 6.48). Two clusters of subjects were created based on morphometric parameters. The mean GT among cluster A subjects was significantly lower than that among cluster B subjects (P=0.015). No significant difference was found between cluster A and B subjects in terms of PV score (P=0.583). Conclusions: Periodontal PV was not associated with GT as measured directly using an ultrasonic device. Sex was a highly significant predictor of periodontal PV. GT was found to be correlated with morphological characteristics of the periodontium.

Surface Deformation Measurement of the 2020 Mw 6.4 Petrinja, Croatia Earthquake Using Sentinel-1 SAR Data

  • Achmad, Arief Rizqiyanto;Lee, Chang-Wook
    • Korean Journal of Remote Sensing
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    • v.37 no.1
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    • pp.139-151
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    • 2021
  • By the end of December 2020, an earthquake with Mw about 6.4 hit Sisak-Moslavina County, Croatia. The town of Petrinja was the most affected region with major power outage and many buildings collapsed. The damage also affected neighbor countries such as Bosnia and Herzegovina and Slovenia. As a light of this devastating event, a deformation map due to this earthquake could be generated by using remote sensing imagery from Sentinel-1 SAR data. InSAR could be used as deformation map but still affected with noise factor that could problematize the exact deformation value for further research. Thus in this study, 17 SAR data from Sentinel-1 satellite is used in order to generate the multi-temporal interferometry utilize Stanford Method for Persistent Scatterers (StaMPS). Mean deformation map that has been compensated from error factors such as atmospheric, topographic, temporal, and baseline errors are generated. Okada model then applied to the mean deformation result to generate the modeled earthquake, resulting the deformation is mostly dominated by strike-slip with 3 meter deformation as right lateral strike-slip. The Okada sources are having 11.63 km in length, 2.45 km in width, and 5.46 km in depth with the dip angle are about 84.47° and strike angle are about 142.88° from the north direction. The results from this modeling can be used as learning material to understand the seismic activity in the latest 2020 Petrinja, Croatia Earthquake.

Complete Genome Sequence and Analysis of Carnation Italian Ringspot Virus from Erigeron annuus (L.) Pers. in Korea

  • Chung Youl Park;Da Hyun Lee;Young Ho Jung;JunHyeok Kim;Mi Hyun Lee;Un Seop Shin;Hee Ho Lee;Cho Hee Park;Chae Sun Na
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.47-47
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    • 2020
  • In this study, we aimed to study carnation italian ringspot virus (CIRV) in Erigeron annuus (L.) Pers. in Bonghwa County, Korea. The collected samples showed mosaic and malformation symptoms. To identify the virus species, we performed high-throughput sequencing, reverse transcription polymerase chain reaction, and cloning. The virus was confirmed to be an unreported species, and therefore we performed genome sequencing of the samples. The complete genome was 4,746 nucleotides in length. The CIRV contained five open reading frames (ORFs), and it showed the typical features of members of the genus Tombusvirus. Phylogenetic analyses revealed that ClRV isolates had the highest nucleotide identities with the CZ isolate (95.89%) from Korea. In recent years, these viruses have sporadically been reported in floral scent and medicinal plants. This research found the first natural host infected with CIRV, and provides baseline information to determine the correlation between weeds and crops.

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Paraffin-based ramjet missile preliminary design

  • Rogerio L.V. Cruz;Carlos A.G. Veras;Olexiy Shynkarenko
    • Advances in aircraft and spacecraft science
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    • v.10 no.4
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    • pp.317-334
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    • 2023
  • This paper presents a basic methodology and a set of numerical tools for the preliminary design of solid-fueled ramjet missiles. An elementary code determines the baseline system configuration comprised of warhead, guidance-control, and propulsion masses and geometries from specific correlations found in the literature. Then, the system is refined with the help of external and internal ballistics codes. Equations of motion are solved for the flight's ascending, cruising, and descending stages and the internal ballistic set of equations designs the ramjet engine based on liquefying fuels. The combined tools sized the booster and the ramjet sustainer engines for a long-range missile, intended to transport 200 kg of payload for more than 300 km range flying near 14,000 m altitude at Mach 3.0. The refined system configuration had 600 mm in diameter and 8,500 mm in length with overall mass of 2,128 kg and 890 kg/m3 density. Ramjet engine propellant mass fraction was estimated as 74%. Increased missile range can be attained with paraffin-polyethylene blend burning at near constant regression rate through primary air mass flow rate control and lateral 2-D air intakes.

Fake News Detector using Machine Learning Algorithms

  • Diaa Salama;yomna Ibrahim;Radwa Mostafa;Abdelrahman Tolba;Mariam Khaled;John Gerges;Diaa Salama
    • International Journal of Computer Science & Network Security
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    • v.24 no.7
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    • pp.195-201
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    • 2024
  • With the Covid-19(Corona Virus) spread all around the world, people are using this propaganda and the desperate need of the citizens to know the news about this mysterious virus by spreading fake news. Some Countries arrested people who spread fake news about this, and others made them pay a fine. And since Social Media has become a significant source of news, .there is a profound need to detect these fake news. The main aim of this research is to develop a web-based model using a combination of machine learning algorithms to detect fake news. The proposed model includes an advanced framework to identify tweets with fake news using Context Analysis; We assumed that Natural Language Processing(NLP) wouldn't be enough alone to make context analysis as Tweets are usually short and do not follow even the most straightforward syntactic rules, so we used Tweets Features as several retweets, several likes and tweet-length we also added statistical credibility analysis for Twitter users. The proposed algorithms are tested on four different benchmark datasets. And Finally, to get the best accuracy, we combined two of the best algorithms used SVM ( which is widely accepted as baseline classifier, especially with binary classification problems ) and Naive Base.

Fisheries in Geray Reservoir could be managed using biometric and reproductive characteristics of the Common carp (Cyprinus carpio L. 1758)

  • Yirga Enawgaw;Ayalew Sisay;Asnaku Bazezew;Solomon Wagaw;Assefa Wosnie
    • Fisheries and Aquatic Sciences
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    • v.27 no.6
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    • pp.337-345
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    • 2024
  • This study looked at some biometric and reproductive aspects of the Common carp (Cyprinus carpio) - the overexploited fish species in the Geray Reservoir as a foundation to develop an efficient fisheries management strategy. 50 fish samples (20 to 44 cm and 130 to 2,400 g) were collected between October and May 2022 using a cast net with a mesh size of 6 cm. The ratio of male to female C. carpio (1:0.52) was deviating from the anticipated 1:1 ratio. The absolute fecundity of C. carpio was relatively low (12,375 to 31,392 eggs). Gonadosomatic index varied from 0.01 to 4.6 (male) to 0.24-12.75 (female), and the spawning period of C. carpio extended from December to January. The length-weight relationships for males (TW = 0.0009TL3.87) and females (TW = 0.0007L3.97) indicate that C. carpio had positive allometric growth; which may have been caused by unsuitable habitat conditions and overfishing. There is a need to develop fisheries management like implementing integrated conservation efforts and reducing wetland farming. For this, this information provides a baseline data.