• Advances in concrete construction
• /
• v.9 no.1
• /
• pp.71-82
• /
• 2020

One of the most suitable methods in structural design is seismic separator. Lead-Rubber Bearing (LRB) is one of the most well-known separation systems which can be used in different types of structures. This system mitigates the earthquake acceleration prior to transferring to the structure efficiently. However, the performance of this system in concrete structures with different heights have not been evaluated thoroughly yet. This paper aims to evaluate the performance of LRB separation system in concrete structures with different heights. For this purpose, three, 16, and 23 story concrete structures are equipped by LRB and exposed to a far-field earthquake. Next, a time history analysis is conducted on each of the structures. Finally, the performance of the concrete structures is compared with each other in the term of their response to the earthquakes and the formation of plastic hinges. The results of the paper show that the rate of change in acceleration response and the ratio of drift along the height of 8 and 23 stories concrete structures are more than those of the 16-stories, and the use of LRB reduces the formation of plastic joints.

• Journal of Environmental Science International
• /
• v.17 no.1
• /
• pp.113-118
• /
• 2008

[ $6{\sim}13mg/L$ ] base water concentration on monthly BOD has been kept at the Geukrak bridge point for this research target and it indicates the water quality under the existed rank. Due to this present condition of water quality, the demage of ecology from the upper stream to the lower one of the bridge could be conjectured. Moreover, nonstructural extinction of the ecology seems to have gotten worse between both the streams of Yeoungsan River. On this research, eco-corridor between the upper stream and the lower stream of the river should be ensured, the ecological demage needs to be cut off, a dispersed discharge method which the existed method of the 1st sewage plant in Gwangju was enhanced to should be inducted for the procuring of various water ecosystem, and the conditions by the scenario suggested from this research could be applied to a water quality model. then, analysis the improvement effect of the water quality adjacent the river. From the test result, Case3-Type1 scenario is thought to be the best one. From the test result with Case3-Type1 when the concentrated discharge was never done, 0.07 mg/L of BOD concentration was increased at the lower stream where Yeoungbon B point (Haksan Bridge) is but the water improvement effect of $0.24{\sim}2.87mg/L$ is thought to have been done at the area of water deterioration.

• Journal of The Korean Association of Information Education
• /
• v.18 no.4
• /
• pp.585-594
• /
• 2014

In terms of development for CMC computer science curriculum was started from 2006 year, and it was confirmed at 2013 year and adapting through 1 to 8 grade. CMC is focused on the "Develop computer fluency, not just computer literacy", "Develop thinking process skills, not just content mastery", and "Highlight the interconnectedness of knowledge, not just address a topic/subject in isolation" as a base of the curriculum. CMC have selected core factors which are Thinking process skills, Computer literacy integrated with fundamental concepts and thinking skills, Thematic integration, Spiral curriculum, and Scalability. Once CMC have been developed as a common computer curriculum by India government, both of computer training course and textbook development were conducted by government. In addition, they are trying to enforce the computer education. It suggests to Korea some significant points which were the necessity of Computer education as an independent subject and the requirement of Software education and Computational thinking as an educational content.

• Biomedical Science Letters
• /
• v.14 no.1
• /
• pp.47-53
• /
• 2008

Hox genes are known to be transcription factors controlling vertebrate pattern formation along the anteroposterior body axis by regulating many target gene expressions during vertebrate embryogenesis. In order to isolate in vivo Hox responsive target genes, ChIP-cloning technique has been applied using Hoxc8 antibody. Here murine embryo of day 11.5 post coitum (E11.5) highly expressing Hoxc8 gene was used after removing head and tail portions where Hoxc8 is rarely expressing. After fixation with formaldehyde, the chromatin DNAs harboring bound proteins were isolated. After sonication, about 0.5- to 1 Kb chromatin DNAs were immunoprecipitated with anti Hoxc8 antibody. After removing the bound proteins with proteinase K, DNAs were isolated, cloned into the pBluescsript II SK vector, and then sequenced. Total 33 random clones sequenced were anlalyzed to be located at 12 different genomic regions. Among these, 8 turned out to be introns and 4 were intergenic regions localized in random chromosomes. The base composition of total cloned genomic sequences (6608 bp) were AT-rich, i.e., 40% GC. When the Hoxc8 core binding sites, such as TAAT, ATTA, TTAT, and ATAA were analyzed total number of 55, 45, 54, and 55 were found, respectively, which are than twice as many as expected number of 26. Although this in silico analysis does not mean that the ChIP-cloned sequence is real Hoxc8 regulatory element in vivo, these results strongly imply that the DNA fragments cloned through chromatin immunoprecipitation could be very much likely the putative Hoxc8 downstream target genes.

• Natural Product Sciences
• /
• v.14 no.3
• /
• pp.161-166
• /
• 2008

A mixture of sixteen cerebrosides, which comprised four cerebroside molecular species (PL-1 ${\sim}$ PL-4) was separated from the roots of Paeonia lactiflora. The structures of cerebrosides were characterized as $1-O-{\beta}$-D-glucopyranosides of phytosphingosines, which comprised a common long-chain base, (2S,3S,4R,8E/Z)-2-amino-8-octadecene-1,3,4-triol with eight fatty acids or 2-hydroxy fatty acids of varying chain lengths ($C_{16}$, $C_{18}$, $C_{20-26}$) linked to the amino group. Aralia cerebroside and its 8Z isomer (PL-1), $1-O-{\beta}$-D-glucopyranosyl-(2S,3S, 4R,8E/Z)-2-[(2'R)-2'-hydroxytetracosanoylamino]-8-octadecene-1,3,4-triol (PL-2), $1-O-{\beta}$-D-glucopyranosyl-(2S,3S,4R, 8E/Z)-2-[(2'R)-2'-hydroxydocosanoylamino]-8-octadecene-1,3,4-triol (PL-3), and $1-O-{\beta}$-D-glucopyranosyl-(2S,3S,4R, 8E/Z)-2-[(2'R)-2'-hydroxytricosanoylamino]-8-octadecene-1,3,4-triol (PL-4) were identified as major components of these cerebroside molecular species. All the major cerebrosides were shown to be a mixture of geometrical isomers (8E and 8Z) of phytosphingosine-type glucocerebrosides possessing 2R-hydroxy fatty acids. In addition, three ${\beta}-sitosterol$ derivatives and adenosine were also separated. The structures of these isolates have been determined on the basis of chemical and spectroscopic evidence.

• The Journal of Korean Society for School & Community Health Education
• /
• v.11 no.1
• /
• pp.117-134
• /
• 2010

Background & Objectives: Recently, problems such as in-school violence of teenagers, gang fight, habitual drinking, smoking, running away from home and group isolation can be regarded as the most fundamental causes of teenagers' deviation. It is said that such fundamental causes are originated from their home, the base for the psychological and behavioral development. Methods: In this study, the data for 3,188 students studying in the 3rd grade at middle school, which have been obtained from the second year survey for the panel of the 2nd grade students in 2004 by to Korea Youth Panel Survey, have been used for the analysis of the study. Results: According to the result of the study, there seems to be no difference between two genders for differences of average values. Regarding the analysis of correlation coefficients between such related variables as domestic violence, self-control, self-worth, self-trust and family relationship (sociability), and teenagers' deviation, When variables increase, teenagers' deviation decreases. Regarding the relationship between domestic violence and teenagers' deviation, physical violence is more related than lingual violence. The relationship between self-control and teenagers' deviation is the highest. By studying the deviation of teenagers exposed to domestic violence and carrying out the regression analysis, physical violence influences, teenagers' deviation was greater. As self-control, self-worth and family relationship(sociability) increase, teenagers' deviation decreases. Regarding the analytic results of this study, the experience of domestic violence seems to influence teenagers' deviation greatly. Among various types of domestic violence, physical violence is analyzed to influence teenagers' deviation greatly. Self-control, self-worth and family relationship(sociability) increase, teenagers' deviation decreases. Conclusions: In order to prevent teenagers' deviation and decrease the second conviction rate, it is necessary to provide a method of decreasing the domestic violence. It is necessary for schools and local communities to provide social support for teenagers.

• Archives of Plastic Surgery
• /
• v.35 no.5
• /
• pp.615-618
• /
• 2008

Purpose: Pyoderma gangrenosum is a rare cutaneous ulcerative disease. First described in 1930, the condition is characterized by progressive ulceration with deeply undermined purple-red edge. The lower extremities are most commonly affected but other parts of the skin and mucous membranes may also be involved. Although medical treatments with topical wound therapy are commonly used, surgical intervention is still controversial. In this paper, we report an atypical case of pyoderma gangrenosum which was characterized by extensive soft tissue breakdown. Methods: A 27-year-old male patient was referred to our institution with a $7{\times}8cm$ sized deeply undermined ulceration with pus-like discharge and fever. Incision and drainage was performed at another clinic 3 days prior to admission to our institution. After a thorough physical examination and the MRI review, a diagnosis of necrotizing faciitis was made. Accordingly, fasciotomy and debridement was performed. However, the wound enlarged progressively and the patient remained highly febrile for 9 days after the treatment. Septic screening did not reveal any occult infection. After a secondary review of the case, the initial diagnosis of necrotizing fasciitis was rejected and changed to pyoderma gangrenosum. With the use of dexamethasone intravenously, the wound improved dramatically and the fever was eliminated. Steroid mediation was tapered with duration of 1 month. The wound was stabilized and subsequently covered with split-thickness skin graft. Results: Split-thickness skin grafting with 1 : 1.5 mesh was successfully taken. Conclusion: Initial clinical features of pyoderma gangrenosum are very similar to that of necrotizing fasciitis. High fever and progressive ulceration with severe pain could invite earlier surgical approach. The advancing wound margins (the well defined violaceous, undermined border and necrotic ulcer base) and lack of isolation of pathogenic organism was used to make the correct diagnosis of pyoderma gangrenosum. We achieved a good result with proper medication and split-thickness skin graft.

• Applied Biological Chemistry
• /
• v.44 no.3
• /
• pp.153-161
• /
• 2001

In order to isolate genes involved in ecdysteroids biosynthesis in plants, total RNA was isolated from Achyranthes japonica Nakai, and RT-PCR was performed using degenerate primers selected based on the results of multi-alignment of four cytochrome P450 genes from plants and a putative ecdysone 20-hydroxylase gene from an insect. Fourteen partial cDNA clones showing unique base sequences were obtained, out of which six showed homologies at the levels of nucleotide and amino acid sequences to the other cytochrome P450 genes known to be involved in the ecdysteroid biosynthesis. Of the six clones, four showed relatively high homologies to a putative ecdysone 20-hydroxylase gene isolated from an insect.

• Structural Engineering and Mechanics
• /
• v.40 no.4
• /
• pp.453-469
• /
• 2011

A one-story, wooden-frame, intermediate-bay model with Dou-Gon designed according to the Building Standards of the Song Dynasty (A.D.960-1279), was tested on a unidirectional shaking table. The main objectives of this experimental study were to investigate the seismic performance of Chinese historic wooden structure under various base input intensities. El Centro wave (N-S), Taft wave and Lanzhou wave were selected as input excitations. 27 seismic geophones were instrumented to measure the real-time displacement, velocity and acceleration respectively. Dynamic characteristics, failure mode and hysteretic energy dissipation performance of the model are analyzed. Test results indicate that the nature period and damping ratio of the model increase with the increasing magnitude of earthquake excitation. The nature period of the model is within 0.5~0.6 s, the damping ratio is 3~4%. The maximum acceleration dynamic magnification factor is less than 1 and decreases as the input seismic power increases. The frictional slippage of Dou-Gon layers (corbel brackets) between beams and plates dissipates a certain amount of seismic energy, and so does the slippage between posts and plinths. The mortise-tenon joint of the timber frame dissipates most of the seismic energy. Therefore, it plays a significant part in shock absorption and isolation.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.36 no.3
• /
• pp.361-374
• /
• 2016

The material property of the rubber has been studied in order to improve the reliability of the finite element model of a lead rubber bearing (LRB) which is a typical base isolator. Rubber exhibits elastic behaviour even within the large strain range, unlike the general structural material, and has a hyper-elastic characteristics that shows non-linear relationship between load and deformation. This study represents the mechanical characteristics of the rubber by strain energy function in order to develop a finite element (FE) model of LRB. For the study, several strain energy functions were selected and mechanical properties of the rubber were estimated with the energy functions. A finite element model of LRB has been developed by using material properties of rubber and lead which were identified by stress tests. This study estimated the horizontal and vertical force-displacement relationship with the FE model. The adequacy of the FE model was validated by comparing the analytical results with the experimental data.