• Title/Summary/Keyword: barrier factor

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BMP-2 Immoblized in BCP-Chitosan-Hyaluronic Acid Hybrid Scaffold for Bone Tissue Engineering

  • Nath, Subrata Deb;Abueva, Celine;Sarkar, Swapan Kumar;Lee, Byong Taek
    • Korean Journal of Materials Research
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    • v.24 no.12
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    • pp.704-709
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    • 2014
  • In this study, we fabricated a novel micro porous hybrid scaffold of biphasic calcium phosphate (BCP) and a polylectrolyte complex (PEC) of chitosan (CS) and hyaluronic acid (HA). The fabrication process included loading of CS-HA PEC in a bare BCP scaffold followed by lypophilization. SEM observation and porosimetry revealed that the scaffold was full of micro and macro pores with total porosity of more than 60 % and pore size in the range of $20{\sim}200{\mu}m$. The composite scaffold was mechanically stronger than the bare BCP scaffold and was significantly stronger than the CS-HA PEC polymer scaffold. Bone morphogenetic growth factor (BMP-2) was immobilized in CS-HA PEC in order to integrate the osteoinductive potentiality required for osteogenesis. The BCP frame, prepared by sponge replica, worked as a physical barrier that prolonged the BMP-2 release significantly. The preliminary biocompatibility data show improved biological performance of the BMP-2 immobilized hybrid scaffold in the presence of rabbit bone marrow stem cells (rBMSC).

How the Disabled Suffer from Information Alienation: An Ethnogrsphy (지체장애인의 정보소외 양상에 대한 문화기술적 연구)

  • Chang, Duk-Hyun;Lim, Shin-Young
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.16 no.2
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    • pp.89-108
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    • 2005
  • The signs of the information society are everywhere, as they became the essentials in ordinary citizen's everyday life. This change requires the modern man to have proper information literacy in order to maintain their lives, and the digital divide between the established and the marginalized in the society is being widened. The gap between the two classes is the single most significant factor in reproducing the socially marginalized such as the urban poor, the disabled, the aged and migrate foreign laborers, core information poor. This study attempts to scrutinize the social problem of information barriers as viewed through the everyday lives of five disabled people. Through various ethnographic positioning and research methods, information needs and information related behaviors, along with general recognitions and reality control strategies are investigated.

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Electrical and Thermo-mechanical Properties of DGEBA Cycloaliphatic Diamine Nano PA and SiO2 Composites

  • Trnka, Pavel;Mentlik, Vaclav;Harvanek, Lukas;Hornak, Jaroslav;Matejka, Libor
    • Journal of Electrical Engineering and Technology
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    • v.13 no.6
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    • pp.2425-2433
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    • 2018
  • This study investigates a new organic based material and its dielectric and mechanical properties. It is a comprehensive nanocomposite comprising a combination of various types of nanofillers with hydrophobic silica nanoparticles (AEROSIL R 974) as a matrix modifier and a polyamide nano nonwoven textile, Ultramid-Polyamide 6, pulped in the electrostatic field as a dielectric barrier. The polymer matrix is an epoxy network based on diglycidyl ether of bisphenol A (DGEBA) and cycloaliphatic diamine (Laromine C260). The designed nanocomposite material is an alternative to the conventional three-component composites containing fiberglass and mica with properties that exceed current electroinsulating systems (volume resistivity on the order of $10^{16}{\Omega}{\cdot}m$, dissipation factor tan ${\delta}=4.7{\cdot}10^{-3}$, dielectric strength 39 kV/mm).

Comparison of Absorption Coefficient according to Test Methods (시험방법에 따른 흡음률 비교)

  • Lee, J.W.;Gu, J.H.;Park, H.K.;Kang, Dae-Joon
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.17 no.5 s.122
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    • pp.373-378
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    • 2007
  • Today, the use of the sound absorptive material is increasing to improve the room acoustics in the auditorium and music hall, etc. Usually, the sound absorption materials have been used to enhance the performance of a noise barrier and improve the room acoustics in construction site. Generally, the sound absorbtion coefficients are the most important factor reflecting the sound absorbtion performance. There are two methods to measure the sound absorption coefficient. The first one is the reverberation room method, and the second is the impedance tube method. In this study, we measure the sound absorbtion coefficients using these two methods, and then we compared the results of the sound absorbtion coefficients to look into the difference of results between reverberation room method and impedance tube method. Also we compared the results of the sound absorbtion coefficients with respect to the size of sample and the volume of reverberation room. From the experiment, we could see that the sound absorbtion coefficients are measured equally for different sample size. But the sound absorbtion coefficients are measured differently according to test methods and test conditions.

Analysis of Alternative Formats Development Policy for the Disabled Persons in the Major Countries (주요 국가의 장애인용 대체자료 개발정책 분석)

  • Yoon, Hee-Yoon
    • Journal of Korean Library and Information Science Society
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    • v.41 no.1
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    • pp.29-49
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    • 2010
  • In an increasingly digital world, knowledge and information accessibility is becoming a key factor to personal, professional and national development. But only 5% of the world's publishing output is made accessible in alternative formats for people who cannot use print. People with disabilities say that the biggest barrier to access to the material they want or need to read is a lack of accessible information. This study aims to analyze the development policies(governance and role, funding and support, production and distribution system, etc.) of alternative formats for people with disabilities in major countries(Australia, Canada, Japan, Korea, Sweden, UK, and USA). And result of this preliminary study will be used as background information for development of the national plan and role model for production and distribution of the alternative formats in Korea.

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Kinetically Controlled Growth of Gold Nanoplates and Nanorods via a One-Step Seed-Mediated Method

  • Hong, Soonchang;Acapulco, Jesus A.I. Jr.;Jang, Hee-Jeong;Kulkarni, Akshay S.;Park, Sungho
    • Bulletin of the Korean Chemical Society
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    • v.35 no.6
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    • pp.1737-1742
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    • 2014
  • In this research, we further developed the one-step seed mediated method to synthesize gold nanoparticles (GNPs) and control their resulting shapes to obtain hexagonal, triangular, rod-shaped, and spherical gold nanostructures. Our method reveals that the reaction kinetics of formation of GNPs with different shapes can be controlled by the rate of addition of ascorbic acid, because this is the critical factor that dictates the energy barrier that needs to be overcome. This in turn affects the growth mechanism process, which involves the adsorption of growth species to gold nanoseeds. There were also observable trends in the dimensions of the GNPs according to different rates of addition of ascorbic acid. We performed further analyses to investigate and confirm the characteristics of the synthesized GNPs.

Computation of Ionic Conductivity at NASICON Solid Electrolyte (III) Na1$\longrightarrow$mid-Na$\longrightarrow$Na2 Conduction Paths (NASICON 고체 전해질의 이온 전도도 계산 (III) 전도경로가 Na1$\longrightarrow$mid-Na$\longrightarrow$Na2인경우)

  • 최진삼;서양곤;강은태
    • Journal of the Korean Ceramic Society
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    • v.33 no.6
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    • pp.645-652
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    • 1996
  • The ionic conductivity of NASICON (Na Super Ionic Conductor) solid electrolyte was simulated by using Monte Carlo Method (MCM)based on a hopping model. We assumed that the conduction path of Na ions is Na1→mid-Na→Na2 where the mid-Na sites are shallow potential sites to induce 'a breathing-like movement' of Na ions in the NASICON framework. The minimum of charge correlation factor Fc and the maximum of appeared at nearby x=2.0 The occupancy of mid-Na site affected the depth of potential barrier and the conduc-tivity of the NASICON. At above x=0.3 ln σT vs. 1/T* plots have been shown Arrhenius behavior but in (VWfc)vs. 1/T* have been shown the Arrhenius type tendency at x=1 MCM results accorded with the experi-mental procedure. The role of mid-Na on Na+ ion conduction could be explained by an additional driving force and a breating-like movement model for motions of Na+ ions in the NASICON framework. As we couldn't clearly remarked the model which is the better it seems reasonable to conclude that these hypothesies are suitable to explain the FIC behavior at NASICON.

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HVEM is a TNF Receptor with Multiple Regulatory Roles in the Mucosal Immune System

  • Shui, Jr-Wen;Kronenberg, Mitchell
    • IMMUNE NETWORK
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    • v.14 no.2
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    • pp.67-72
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    • 2014
  • The herpes virus entry mediator (HVEM) is a member of the tumor necrosis factor receptor superfamily (TNFRSF), and therefore it is also known as TNFRSF14 or CD270 (1,2). In recent years, we have focused on understanding HVEM function in the mucosa of the intestine, particularly on the role of HVEM in colitis pathogenesis, host defense and regulation of the microbiota (2-4). HVEM is an unusual TNF receptor because of its high expression levels in the gut epithelium, its capacity to bind ligands that are not members of the TNF super family, including immunoglobulin (Ig) superfamily members BTLA and CD160, and its bi-directional functionality, acting as a signaling receptor or as a ligand for the receptor BTLA. Clinically, Hvem recently was reported as an inflammatory bowel disease (IBD) risk gene as a result of genome wide association studies (5,6). This suggests HVEM could have a regulatory role influencing the regulation of epithelial barrier, host defense and the microbiota. Consistent with this, using mouse models, we have revealed how HVEM is involved in colitis pathogenesis, mucosal host defense and epithelial immunity (3,7). Although further studies are needed, our results provide the fundamental basis for understanding why Hvem is an IBD risk gene, and they confirm that HVEM is a mucosal gatekeeper with multiple regulatory functions in the mucosa.

An Analysis on the Leakage Current of Drain-offset Poly-Si TFT′s (드레인오프셋트 다결정실리콘 박막트랜지스터의 누설전력 해석)

  • 이인찬;김정규;마대영
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.14 no.2
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    • pp.111-116
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    • 2001
  • Poly-Si TFT's(Polysilicon thin filmtransistors) have been actively studied due to their applications in active matrix liquid crystal displays and active pull-up devices of CMOS SRAM's. For such applications, the leakage current has to be in the range of sub-picoampere. However, poly-Si TFT's suffer from anomalous high leakage currents, which is attributed to the emission of the traps present at gain boundaries in the drain junction. The leakage current has been analyzed by the field emission via grain-boundary traps and thermionic field emission over potential barrier located at the grain boundary. We found that the models proposed before are not consistent with the experimental results at far as drain-offset poly-Si TFT's we fabricated concern. In this paper, leakage current of drain-offset poly-Si TFT's with different offset lengths was studied. A conduction model based on the thermionic emission of the tunneling electrons is developed to identify the leakage mechanism. It was found that the effective grain size of the drain-offset region is important factor in the leakage current. A good agreement between experimental and simulated results of the leakage current is obtained.

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Effects of PEDOT:PSS Buffer Layer and Cathode in a Device Structure of $ITO/PEDOT:PSS/TPD/Alq_3/Cathode$ ($ITO/PEDOT:PSS/TPD/Alq_3/Cathode$ 소자 구조에서 PEDOT:PSS 층과 음전극의 영향)

  • Kim, S.K.;Chung, D.H.;Lee, H.D.;Oh, H.S.;Cho, H.N.;Lee, W.J.;Kim, T.W.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.07b
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    • pp.1003-1006
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    • 2003
  • We have investigated the effect of hole-injection buffer layer and cathodes in organic light-emitting diodes u sing poly (3,4-ethylenedioxythiophene) : poly (stylenesulfonate) (PEDOT: PSS) in a device structure of $ITO/PEDOT:PSS/TPD/Alq_3/Cathode$. Polymer PEDOT:PSS buffer layer was made using spin casting method. Current-voltage, luminance-voltage characteristics and efficiency of device were measured at room temperature with a variation of cathode materials. The device with LiF/Al cathode shows an improvement of external quantum efficiency approximately by a factor of ten compared to that of Al cathode only device. Our observation shows that the energy barrier-height in cathode side is important in improving the efficiency of the organic light-emitting diodes.

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