• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.321-326
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• 2015

Background: The aim of this study was to explore the prognostic role of metabolic response to chemotherapy, determined by FDG-PET, in patients with metastatic non-small-cell lung cancer (NSCLC). Materials and Methods: Thirty patients with metastatic NSCLC were analyzed for prognostic factors related to overall survival (OS) and progression free survival (PFS). Disease evaluation was conducted with FDG-PET/CT and contrast-enhanced CT prior to and at the end of first-line chemotherapy. Response evaluation of 19 of 30 patients was also performed after 2-3 cycles of chemotherapy. Morphological and metabolic responses were assessed according to RECIST and PERCIST, respectively. Results: The median OS and PFS were 11 months and 6.2 months, respectively. At the end of first-line chemotherapy, 10 patients achieved metabolic and anatomic responses. Of the 19 patients who had an interim response analysis after 2-3 cycles of chemotherapy, 3 achieved an anatomic response, while 9 achieved a metabolic response. In univariate analyses, favorable prognostic factors for OS were number of cycles of first-line chemotherapy, and achieving a response to chemotherapy at completion of therapy according to the PERCIST and RECIST. The OS of patients with a metabolic response after 2-3 cycles of chemotherapy was also significantly extended. Anatomic response at interim analysis did not predict OS, probably due to few patients with anatomic response. In multivariate analyses, metabolic response after completion of therapy was an independent prognostic factor for OS. Conclusions: Metabolic response is at least as effective as anatomic response in predicting survival. Metabolic response may be an earlier predictive factor for treatment response and OS in NSCLC patients.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.569-573
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• 2016

Background: A colorectal cancer screening program was piloted in two districts of Kedah in 2013. There is scarcity of information on colorectal cancer screening in Malaysia. Objective: Thus, this research was conducted to evaluate the colorectal cancer screening program in the districts to provide insights intop its efficacy. Materials and Methods: A cross sectional study was conducted using data on the colorectal cancer screening program in 2013 involving Kota Setar and Kuala Muda districts in Malaysia. We determined the response rate of immunochemical fecal occult blood test (iFOBT), colonoscopy compliance, and detection rates of neoplasia and carcinoma. We also compared the response of FOBT by demographic background. Results: The response rate of FOBT for first iFOBT screening was 94.7% while the second iFOBT screening was 90.7%. Participants from Kuala Muda district were 27 times more likely to default while Indians had a 3 times higher risk of default compared to Malays. The colonoscopy compliance was suboptimal among those with positive iFOBT. The most common finding from colonoscopy was hemorrhoids, followed by tubular adenoma. Detection rate of carcinoma and neoplasia for our program was 1.2%. Conclusions: In summary, the response rate of iFOBT was encouraging but the colonoscopy compliance was suboptimal which led to a considerably low detection rate.

• 패션비즈니스
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• 제22권3호
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• pp.16-29
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• 2018

The present study examines whether consumers' perception of waiting time and their behavioral intentions are influenced by the presence of background music in an online shopping environment. In particular, this study aims to explain the underlying mechanism for the effects of background music on consumers' perceived wait and behavioral intentions toward the online retailer by proposing the mediating role of emotions drawing on the Stimulus-Organism-Response (S-O-R) framework. A lab experiment was employed to test the hypotheses. A total of 102 college students were used for data analyses. Results show that the presence of music has a significant impact on participants' emotions, perceived waiting time, and approach behavior. Moreover, the findings show that pleasure and the perceived waiting time serve as mediators in the relationship between the presence of music and approach behavior. Implications of the model for theory, practice, and further research are discussed.

• 대한인간공학회지
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• 제32권3호
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• pp.217-227
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• 2013

Objective: The purpose of this study was to analyze 'response time', 'peak response time' and 'overshoot value' for each muscle by applying the EMG signal to the vehicle response in ISO 7401 and to quantify the response of the driver according to vehicle characteristics by comparing vehicle characteristics and muscle responses of the driver. Background: The Open-loop test defined in international standards ISO 7401 is the only method for evaluating the performance of the vehicle. However, this test was focused only on mechanical responses, not driver's ones. Method: One skilled male driver(22 yrs. experience) was participated in this experiment to measure muscle activities of the driver in transient state. Then the seven muscle signals were applied to calculate 'response time', 'peak response time', and 'overshoot value'. Results: In the analyses of the EMG data, the effects of vehicle type and muscle were statistically significant on the 'response time' and 'peak response time'. Also, the effects of vehicle type, muscle, and lateral acceleration level were statistically significant on the 'overshoot value' in this study. According to the analyses of the vehicle motion data, vehicle motion variable(LatAcc, Roll, YawVel) was statistically significant on the 'response time' and vehicle type, vehicle motion variable, and lateral acceleration level were statistically significant on the 'peak response time', respectively. Conclusion: In the analyses of the 'response time' and 'overshoot value', the data of muscle activities(EMGs) was better index that could evaluate the vehicle characteristic and performance than the data of vehicle motion. In case of peak response time, both EMG and vehicle motion data were good index. Application: The EMGs data from a driver might be applicable as index for evaluation of various vehicle performances based on this study.

• 한국정보통신학회논문지
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• 제20권9호
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• pp.1673-1678
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• 2016

음성인식처리 분야에서 배경잡음으로 인하여 음성입력이 배경잡음으로 잘못 판단되는 원인이 되어 음성인식율의 저하를 초래한다. 이러한 종류의 잡음대책은 단순하지 않으므로 보다 고도한 잡음처리기술이 필요하게 된다. 따라서 본 논문에서는 잡음환경 중에서 정상적인 배경잡음 혹은 비정상적인 배경잡음과 지속 시간이 짧은 음성을 구별하는 알고리즘에 대하여 기술한다. 본 알고리즘은 다른 종류의 잡음과 음성을 구별하는 중요한 수단으로서 개량된 음성의 특징파리미터를 사용한다. 다음으로 다층퍼셉트론 네트워크에 의하여 잡음의 종류를 추정하는 알고리즘에 대해서 기술한다. 본 실험에서는 잡음과 음성이 구별이 가능하도록 실험적으로 확인하였다.

• 대한조선학회논문집
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• 제40권6호
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• pp.1-11
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• 2003

For an accurate shock response analysis of a floating structure such as a naval surface ship subjected to an UNDEX(UNDerwater Explosion), the cavitation effects due to reflected wave at free surface and wetted structural surface should be considered. In this study, for the consideration of cavitation effects an effective method using LS-DYNA/USA and its theoretical background were presented. Through the application of the analysis of bulk cavitation phenomena in the free field, it could be confirmed that almost the same results were obtained between LS-DYNA/USA code and the analytical method. for the investigation of cavitation effects from the structural shock response characteristics, three dimensional UNDEX shock response analysis of an idealized ship model was also carried out It could be found that the cavitation Phenomena gave significant effects on the structural shock response characteristics, and especially that the shock loadings calculated at the installed location of shipboard equipment were underestimated in the case of no consideration of the cavitation effects, which might cause the severe mistake in its shock-resistance design.

• 한국항공운항학회지
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• 제26권4호
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• pp.64-75
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• 2018

A status of air traffic controller is a government officer and air traffic controllers who work at airport are divided by duty rating and work experience. Abiding by law, rules and regulation, air traffic controllers are working together based on mutual trust. This paper's theoretical background is based on cultural bias theory. The theory divide people group into four groups according to cultural bias such as fatalism, hierarchy, individualism and egalitarianism. A research model was designed how such four cultural bias could affect air traffic controller's risk response in case of emergency or abnormal situation during their work. Depend on empirical research, it was found that air traffic controllers perceived they had been more biased to fatalism than hierarchy. The characteristics of fatalism group are as follows: first of all, they follow rigid rules and regulation. However, they have less self-efficacy compared to other government officers. According to structural equation model, air traffic controller's fatalism had a significant negative effect on organizational royalty. Their royalty, however, had a very significant positive effect on planning response and immediate response.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1991년도 춘계학술대회
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• pp.18-21
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• 1991

In this paper, the effect of background grey levels on the visual perception of target image displayed on CRT monitor has been investigated. The purpose of this study is to investigate the efficacy of CRT monitor as a display medium of image information especially in medical imaging field. Three sets of experiments have been performed in this study; the first was to measure the luminance response of CRT monitor and to find the best fitting equation, and the second was the psychophysical experiment measuring the threshold grey level difference between the target image and the background required for visual discrimination for various background grey levels, and the third was to develop a visual model that is predictable of the threshold grey level difference measured in the psychophysical experiment. The result of psycophysical experiment shows that the visual perception performance is significantly degraded in the range of grey levels lower than 50, which is turned out due to the low luminance change of CRT monitor in this range while human eye has been adapted to relatively bright ambient illumination.

• 대한의용생체공학회:의공학회지
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• 제14권1호
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• pp.63-72
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• 1993

In this paper, the effect of background grey levels on the visual perception of target image displayed on CRT monitor has been investigated. The purpose of this study is to investigate the efficacy of CRT monitor as a display medium of image Information especially in medical imaging field. Tllree sets of experiments have been performed in this study : the first was to measure the luminance response of CRT monitor and to find the best fitting equation, and the second was the psychophysical experiment measuring the threshold grey level differences between the target image and the background required for visual discrimination (or various background grey levels, and the third was to develop a visual model that is predictable of the threshold grey level difference measured in the psychophysical experiment. The result of psycophysical experiment shows that the visual perception performance is significantly degraded in the range of grey levels lower than 50, which is turned out due to she low luminance change of CRT monitor in this range while human eye has been adapted lo relatively bright ambient illumination. And it Is also shown in the simulation study using the developed visual model that the dominant factor degrading the visual performance is the reflected light from the monitor surface by ambient light in general illumination condition.

• Nuclear Engineering and Technology
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• 제55권10호
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• pp.3591-3598
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• 2023

Photoneutron background spectroscopy observations at linac are essential for directing accelerator shielding and subtracting background signals. Therefore, we constructed a Bonner Sphere Spectrometer (BSS) system based on an array of BF₃ gas proportional counter tubes. Initially, the response of the BSS system was simulated using the MCNP5 code. Next, the response of the system was calibrated by using neutrons with energies of 2.86 MeV and 14.84 MeV. Then, the system was employed to measure the spectrum of the ²⁴¹Am-Be neutron source, and the results were unfolded by using the Gravel and EM algorithms. Using the validated system, the undesirable neutron spectrum of the 120 MeV electron linac was finally measured and acquired. In addition, it is demonstrated that the equivalent undesirable neutron dose at a distance of 3.2 m from the linac is 19.7 mSv/h. The results measured by the above methods could provide guidance for linac-related research.