• Korean Journal of Pharmacognosy
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• v.18 no.2
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• pp.89-93
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• 1987

Chemical investigation of the inhibitory compound on leucocyte migration from Melilotus officinalis has led to the isolation and characterization of azukisaponin V $(3-O-[{\alpha}-L-rhamonopyranosyl(1{\rightarrow}2)-{\beta}-D-glucopyransosyl(1{\rightarrow}2)-{\beta}-D-glucuronopyranosyl]-soyasapogenol B)$ as the carboxylate form, which exhibits potent leucocyte migration inhibitory activity at a dose of 6mg/rat.

• Archives of Pharmacal Research
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• v.11 no.3
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• pp.197-202
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• 1988

A new saponin, 3-O-[${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}2)$-${\beta}$-D-glucopyranosyl$(1{\rightarrow}2)$-${\beta}$-D-glucuronopyranosyl]soyasapogenol B carboxylate (6) has been isolated from the medicinal plant yellow sweetclover together with azukisaponin II(7), robinin(8), and clovin(9). 7,8, and 9 are reported for the first time from this plant. The new saponin(6) exhibited inhibitory action on leucocyte migration in inflammation.