• Journal of Preventive Medicine and Public Health
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• 제46권6호
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• pp.336-345
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• 2013

Objectives: Research has shown that obesity appears to spread through social ties. However, the association between other characteristics of social networks and obesity is unclear. This study aimed to identify the association between social network characteristics and body mass index (BMI, $kg/m^2$) in an elderly Korean population. Methods: This cross-sectional study analyzed data from 657 Koreans (273 men, 384 women) aged 60 years or older who participated in the Korean Social Life, Health, and Aging Project. Network size is a count of the number of friends. Density of communication network is the number of connections in the social network reported as a fraction of the total links possible in the personal (ego-centric) network. Average frequency of communication (or meeting) measures how often network members communicate (or meet) each other. The association of each social network measure with BMI was investigated by multiple linear regression analysis. Results: After adjusting for potential confounders, the men with lower density (<0.71) and higher network size (4-6) had the higher BMI (${\beta}$=1.089, p=0.037) compared to the men with higher density (>0.83) and lower size (1-2), but not in the women (p=0.393). The lowest tertile of communication frequency was associated with higher BMI in the women (${\beta}$=0.885, p=0.049), but not in the men (p=0.140). Conclusions: Our study suggests that social network structure (network size and density) and activation (communication frequency and meeting frequency) are associated with obesity among the elderly. There may also be gender differences in this association.

• 한국물환경학회지
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• 제29권3호
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• pp.420-427
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• 2013

In this study, the ecological characteristics of Limnoperna fortunei were surveyed as a preceding research to solve the problem such as biofouling or biowaste caused by those organisms in the closed water pipeline. Limnoperna fortunei was collected not in the main reaches of Somjin River but inside and outside of the intake tower which is located in the lower part of Sueo Reservoir. The dense populations were found at the inlet mouth and near part of the pipeline. Their byssuses were formed as a thick and tightly interwind mat. The rusted parts of the pipeline hold relatively more shells than those of the normal parts. Average count of the numbers ranged $12.1{\sim}136.5ind./m^2$ through the sampling stations (A,B and C). The amount of attached shells at each station were A=386, B=258, and C=71, respectively. The relationships of shell height-length and shell length-width were proportional. The majority sizes in each station ranged A=20.01~22.00 mm (33.9%), B=10.01~14.00 mm (51.2%), and C=18.01~20.00 mm (22.5%), 24.01~26.00 mm (21.1%), respectively. Most of the bigger size of shells on C station was found dead. The ecological habitat seemed less suitable for Limnoperna fortunei when they located farther away from the intake tower of reservoir. From now on, it is necessary to consider the continuous monitoring of this organism.

• Journal of Chest Surgery
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• 제20권3호
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• pp.458-472
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• 1987

A heart supplies bloods of about 15, 000 liters to each human organ in a day. A normal function of heart valves is necessary to this act of heart. The disease of heart valve develops to a narrowness of a closure, resulting in an abnormal circulation of bloods. In an attempt to eliminate the affliction of heart valves, the operation method to repair with artificial heart valves has been developed and saved numerous patients over past 30 years. This replacement operation has been performed since early 1960`s in Korea, but all the artificial heart valves used are imported from abroad with very high costs until recent years. The artificial heart valve using pyrolytic carbon has been developed at KAIST, which was proved to be stable in the mechanical performance and durability. Therefore, the in viva performance of this valve was examined through animal tests. The artificial heart valves used in this study are tilting disc type valves, in which the disc were made of graphite coated with pyrolytic carbon and the cages were made of titanium. In viva testings of these valves were performed in 12 dogs, in which right ventriculo-pulmonary arterial [Croup I] or inter-aortic [Croup IV] valved conduit was implanted using polytetrafluoroethylene conduits containing KAIST valve and aortic valve [Group II] or pulmonary valve [Croup III] was replaced by a KAIST valve with a 21mm or 19mm tissue annulus diameter. In group I and II, pre-and post-operative transvalvular pressure gradient was measured and compared with other prosthetic valves. During post operative period laboratory examination was performed including hemoglobin, hematocrit, red cell count, white cell, lactic acid dehydrogenase and platelet. The eight surviving dogs were sacrificed and autopsy was performed at 2, 6, and 8 weeks. KAIST valve has low transvalvular gradient and relatively high orifice area. Average ventriculo-aortic peak systolic transvalvular gradient was 14 mmHg in 21 mm valve and 19 mmHg in 19 mm valve. The valve has slight intravascular hemolysis effect. Thrombogenic effect of low polishing quality and eddy currents around small orifice is high. The valve has vulnerability of disc movement. These animal tests suggest that the improvement of the heart valve design, surface polishing state and prescription methods.

• 정보처리학회논문지D
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• 제8D권2호
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• pp.175-180
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• 2001

본 논문은 미래의 소프크웨어 공장 수나 고장시간 예측 정확성을 얻기 위해, 뉴로-피지 시스템을 이용할 경우 최적의 검증 데이터 할당 비율에 대한 연구이다. 훈련 데이터가 주어졌을 때, 과소 적합과 과잉 적합을 회피하면서 최적의 일반화 능력을 얻기 취해 Early Stopping 방법이 일반적으로 사용되고 있다. 그러나 훈련과 검증 데이터로 얼마나 많은 데이터를 할당갈 것인가는 시행착오법을 이용해 경험적으로 해를 구해야만 하며, 과다한 시간이 소요된다. 최적의 검증 데이터 양을 구하기 위해 규칙 수를 증가시키면서 다양한 검증 데이터 양을 할당하였다. 실험결과 최소의 검증 데이터로도 좋은 예측 능력을 보였다. 이 결과는 뉴로-퍼지 시스템을 소프트웨어 신뢰성 분야에 적용시 실질직언 지침을 제공할 수 있는 것이다.

• 정보처리학회논문지A
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• 제13A권1호
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• pp.11-18
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• 2006

다양한 네트워크로 구성된 인터넷 환경에서 오버레이 홉 수를 최소화하는 Chord를 비롯한 기존의 분산 해싱 테이블 기반의 피어-투-피어 시스템에서는 목적 노드까지의 실질적인 질의 라우팅 시간을 줄일 수 없다. 따라서 제안하는 적응적 근접경로 선택기법에서 각 노드는 라우팅테이블의 엔트리 노드 중 지연시간을 최소로 하는 노드를 선택하여 질의 메시지를 전달하도록 한다. 이를 위하여 각 엔트리의 목적지까지의 지연시간을 큐 라우팅 알고리듬과 지수적 최근-가중치 평균을 이용해 예측하여 검색 테이블로 저장하고, 노드들 간 메시지 전달 시 이 정보를 교환하여 추가 부하 없이 검색 테이블에 반영한다. 시뮬레이션을 통해 제안하는 기법이 전채 검색 시간과 흡 간 지연시간에 있어서 근접성을 고려하지 않은 Chord나 CFS의 서버 선택 알고리즘에 비해 월등히 좋은 성능을 보임을 확인할 수 있다.

• Clinical and Experimental Pediatrics
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• 제60권1호
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• pp.24-29
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• 2017

Purpose: Previously, Kawasaki disease (KD) treatment with low-dose aspirin was administered for 6-8 weeks after the acute phase. However, inflammatory marker levels normalize before 6-8 weeks. In this study, we aimed to investigate the clinical outcome of short-term low-dose aspirin treatment based on inflammatory and thrombotic marker levels. Methods: We performed a retrospective review of the medical records of patients with KD who were hospitalized at Chungnam National University Hospital between September 2012 and May 2014. When fever subsided, low-dose aspirin treatment was started. Inflammatory (white blood cell count, erythrocyte sedimentation rate, and C-reactive protein) and thrombotic markers (D-dimer) were monitored at follow-ups conducted in 1- to 2-week intervals. The low-dose aspirin administration was terminated when both markers were normalized and no cardiovascular complications were observed. Results: Eighty-four patients with KD (complete KD, n=49; incomplete KD, n=35) were enrolled. The inflammatory and thrombotic marker levels were normalized within 3-4 weeks on average. At the beginning the low-dose aspirin treatment, 9 patients had coronary artery lesions but 75 did not. When the low-dose aspirin administration was terminated at the time the inflammatory marker levels were normalized, no new CALs developed during the follow-up at 6-8 weeks. Conclusion: Most of the inflammatory marker levels were normalized within 3-4 weeks after the acute phase of KD. New cardiovascular complications did not develop during the course of the short-term aspirin treatment based on the inflammatory marker levels, clinical findings, and echocardiography.

• 정보관리학회지
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• 제33권3호
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• pp.195-217
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• 2016

본 연구는 결혼이주여성들의 도서관 이용의 어려움을 도서관 불안 척도를 통해 측정하고 이를 해결할 수 있는 방안에 대해 제안하였다. 연구방법은 광주에 위치한 공공도서관 5곳에서 2015년 12월부터 2016년 3월까지 도서관 불안에 관한 설문조사를 실시하여 137명의 응답을 분석에 활용하였다. 연구결과, 결혼이주여성들의 전체 도서관 불안 점수는 5점 척도에서 2.91점으로 기존의 선행연구들과 비교하여 비교적 높은 편이었다. 개인특성에 따른 도서관 불안 결과를 분석해 본 결과 한국어 능력, 남편직업, 이용목적, 방문횟수, 도서관거리, 그리고 모국경험의 차이에 따라 통계적으로 유의한 차이를 보였다. 연구결과를 바탕으로 결혼이주여성의 도서관 불안 완화를 위한 방안을 제안하였다.

• Journal of Nutrition and Health
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• 제26권1호
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• pp.3-12
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• 1993

This study was performed to investigate effects of dietary fat content and degree of saturation on the function of the immune system. Sixty male BALB/c mice average-weighing 17g were divided into three dietary groups: 5% safflower oil group, 20% safflower oil group, 19.3% beef tallow & 0.7% safflower oil group. Food intake and body weight were measured every day. At 4th, 7th, 10th week after dietary treatment, organ weight measurements, delayed-type hypersensitivity test, plaque forming cell test, agglutination test, differential white cell count and histological examination of spleen were performed. Results are follows; 1) Body weight, food intake and calorie intake were not different in the three dietary groups during the experimental period($\alpha$=0.05). 2) Liver weight was significantly higher in 5% safflower oil group($\alpha$=0.05). Spleen index was slightly higher in mice fed 5% safflower oil and 19.3% beef tallow & 0.7% safflower oil. Thymus index in all mice was decreased by aging. 3) Delayed-type hypersensitivity of the mice fed 5% safflower oil and 19.3% beef tallow & 0.7% safflower oil was significantly higher than that of the mice fed 20% safflower oil. 4) The number of plaque forming cell was significantly reduced at 10th week compared to 7th week in all group($\alpha$=0.05). Although there was no difference in plaque forming cell among three groups at 10th week, 5% safflower oil group showed slightly higher plaque forming cell than 20% safflower oil group at 7th week. 5) At 4th week, agglutination test seems to be higher in 5% safflower oil group and 19.3% beef tallow & 0.7% safflower oil group compared to 20% safflower oil group. 6) Percentage of neutrophil and eosinophil was slightly reduced in 20% safflower oil group. 7) Spleen tissue was not affected by and dietary treatments. According to our results, the higher the fat content & unsaturation of the diet the lower the cell-mediated immunity of the mice. Humoral-immunity did not appear to be affected by the dietary manipulation. However humoral-immunity was decreased significantly by aging in all dietary groups.

• Journal of Nutrition and Health
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• 제35권9호
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• pp.952-961
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• 2002

The purpose of this study was to compare nutrient intakes and the serum iron status of 74 Food and Nutrition major, and 45 non-major, female students at a university in Incheon. This cross-sectional survey was conducted using a self-administered questionnaire and the data were analyzed by the SPSS 10.0 program. The nutrient intake data collected from three-day dietary recalls were analyzed by the Computer Aided Nutritional Analysis Program. Anthropometric data and hematological indices of iron in the blood were measured. Average heights, weights, body fat and mid-upper arm circumference of Food and Nutrition major and non-major female students were 160.3 cm, 53.5kg, 25.8%, 23.7cm and 159.8cm, 55.5kg, 28.9%, 24.8cm, respectively. There were significant differences in body fat percentage and mid-upper arm circumference between the major and non-major students. In all subjects, daily dietary intakes of nutrients- except protein, vitarrlin B1, vitamin C and phosphorus - were lower than the Korean RDA. In particular, calcium and iron intakes of all subjects were under 60% of the Korean RDA. Values of RBC (red blood cell) count, Hb (hemoglobin), Hct (hematocrit), MCV (mean cell volume), MCH (mean cell hemoglobin), and MCHC (mean corpuscular hemoglobin concentration) of the non-major students were significantly higher compared to those of the major students. The diastolic blood pressure of the major students was negatively correlated with MCV, MCH, TS, and serum iron levels. Triceps skinfold thickness, mid-upper arm circumference and waist-to-hip ratios of the non-major students were negatively correlated with TIBC. Fat intake was positively correlated with RBC, Hb, Hct, and TIBC (total iron binding capacity) in the major students. Vitamin C intake was positively correlated with serum iron in the major students. Carbohydrate intake was positively correlated with Hb, Hct, and MCHC in the non-major students. Niacin and iron intakes were positively correlated with Hb and Hct in the non-major students. Therefore, nutrition education is necessary for female university students to improve nutritional status and to practice optimal nutrition strategies. (Korean J Nutrition 35(9) : 952~961, 2002)

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6773-6779
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• 2014

Background: Nanotechnology opens new applications in many fields including medicine. Among all metallic nanoparticles, silver nanoparticles (silver NPS) have proved to be the most effective against a large variety of organisms including toxic cyanobacteria. Materials and Methods: Silver NPs were biosynthesized in vivo with different alga species namely, Spirulina piatensis, Chlorella vulgaris and Scenedesmus oh/iquus following two scenarios. First: by suspending a thoroughly washed algae biomass in 1 mM aqueous $AgN0_3$ solution. Second: by culturing them individually in culture media containing the same concentration of $AgN0_3$. Silver NPs were characterized using UV-Vis spectroscopy, transmission electron microscopy (TEM), energy dispersive analysis (EDX) and Fourier transform infra-red (FfIR) spectroscopy. The biosynthesized silver NPs were tested for cytotoxic activity against a cancer promoter cyanobacteruim Microcystis aeruginosa, considering effects on cell viability and chlorophyll content. Results: The surface plasmon band indicated the biosynthesis of silver NPs at ~400 nm. Transmission electron microscopy (TEM) revealed that the silver NPs had a mean average size below 100 nm. Energy-dispersive analysis X-ray (EDX) spectra confirmed the presence of silver element. FfIR spectral analyses suggested that proteins and or polysaccharides may be responsible for the biosynthesis of silver NPs and (-COO-) of carboxylate ions is responsible for stabilizing them. The toxic potentialities ofthe biosynthesized silver NPs against the cancer promoter cyanobacterium, Microcystis aeruginosa showed high reduction in viable cells count and the total chlorophyll content. Conclusions: The potential activity of the biosynthesized silver NPs from the studied algae species against Microcystis aernginosa cells is expected to be mainly mediated by the release of silver ions (Ag+) from the particle surface and bioactive compounds as indicated by FfIR analysis.