• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1725-1728
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• 2015

Objective: To explore effects of paclitaxel-loaded poly lactic-co-glycolic acid (PLGA) particles on the viability of human hepatocellular carcinoma (HCC) HepG2 cells. Materials and Methods: The viability of HepG2 cells was assessed using MTT under different concentrations of prepared paclitaxel-loaded particles and paclitaxel (6.25, 12.5, 25, 50, and 100 mg/L), and apoptosis was analyzed using Hochest33342/Annexin V-FITC/PI combined with an IN Cell Analyzer 2000. Results: Paxlitaxel-loaded nanoparticles were characterized by narrow particle size distribution (158.6 nm average particle size). The survival rate of HepG2 cells exposed to paclitaxel-loaded PLGA particles decreased with the increase of concentration and time period (P<0.01 or P<0.05), the dose- and time-dependence indicating sustained release (P<0.05). Moreover, apoptosis of HepG2 cells was induced, again with an obvious dose- and time-effect relationship (P<0.05). Conclusions: Paclitaxel-loaded PLGA particles can inhibit the proliferation and induce the apoptosis of HCC HepG2 cells. This new-type of paclitaxel carrier body is easily made and has low cost, good nanoparticle characterization and sustained release. Hence, paclitaxel-loaded PLGA particles deserve to be widely popularized in the clinic.

• 복식문화연구
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• 제24권2호
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• pp.233-247
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• 2016

The purpose of this study is to propose a specialized clothes-sizing system for elderly (aged 60~79) obese women satisfying the following conditions based on the data from the fifth Korean Agency for Technology and Standards (2004): a Rohrer's index of over 1.6, a BMI of over 25, and a WHR of over 0.85. The lower bodies of elderly obese women tends to be shorter and wider than average. Particularly, their torsos from the chest to the waist tend to be more obese than other areas. According to the KS standards, the clothes-sizing system sets up its size intervals as follows: 5cm in stature, 5cm and 3cm in bust, 3cm in waist, and 3cm in hip. Based on the dualistic distribution of each section, the names of the sections indicating high distribution are suggested. For suit tops, 11 sizes are selected as distributed in the 145-155cm stature section and 91-103cm bust section. For casual tops, nine sizes are selected as distributed in the 145-155cm stature section and 90-105cm bust section. For bottoms, 11 sizes are selected as distributed in the 82-97cm waist section and 91-97cm hip section. According to the KS standards, detailed sizes are suggested in the division of basic and reference areas.

• Asian-Australasian Journal of Animal Sciences
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• 제15권2호
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• pp.179-183
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• 2002

The fragment in intron I of FSH-${\beta}$ gene was amplified by PCR. According to the polymorphism, we analyzed the distribution of FSH-${\beta}$ retroposon in different pig breeds; its inheritance pattern in Large White${\times}$Meishan reference family; and the association of FSH-${\beta}$ retroposon with litter size, female reproductive organs measurement, ultrasonic backfat and other traits. The results showed that almost each Chinese indigenous pig had the retroposon, while foreign pig breeds rarely had; the frequencies of porcine FSH-${\beta}$ retroposon were strongly associated with breeds (p<0.01); the pattern of inheritance was consistent with Mendelian fashion; total number born (TNB) and number born alive (NBA) were increased per FSH-${\beta}$ retroposon (p<0.01) with additive effects of 1.2-1.8 and 1.4-1.8 pigs/litter, respectively; between the FSH-${\beta}$ retroposon carriers and non-carriers, there was an insignificant difference in the measurement of female reproductive organs, body weight at birth, backfat thickness, loin meat height, lean meat percentage, teat number, days to 100 kg, and average daily gain.

• E2M - 전기 전자와 첨단 소재
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• 제10권7호
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• pp.659-667
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• 1997

The influence of SiO$_2$on the microstructure and electrical properties of zinc oxide varistor was investigated. Zn$_2$SiO$_4$third phase in the sintered body was found at grain boundaries, multiple grain junctions, and occasionally within ZnO grains. This phase acted as a grain growth inhibitor, which retard the grain growth of the ZnO matrix by impeding migration on the grain boundaries. As SiO$_2$ addition increases, average grain size decreased from 40.6${\mu}{\textrm}{m}$ to 26.9${\mu}{\textrm}{m}$ due to the pinning effect by Zn$_2$SiO$_4$ and drag effect by Si segregation at grain boundaries, the breakdown voltage consequently increased. When SiO$_2$ addition is increased, interface state density decreased, however, the barrier height increased by decrease of donor concentration, as a result, the nonlinear exponent increased and leakage current decreased. While, as SiO$_2$ addition increase, it was found that the apparent dielectric loss factor shows a tendency of decrease. Wholly, electrical properties of zinc oxide varistor can be said to be improved by SiO$_2$addition.

• 한국분말재료학회지
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• 제3권3호
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• pp.181-187
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• 1996

Cobalt and VC powders were ball milled with M2 grade high speed steel powders under various ball to powder ratios. The powders milled under higher ball to powder ratio become finer, more irregular and have a broader size distribution, and thus possess a lower compressibility and a better sinterability regarding densification. Increasing the ball to powder ratio lowered the sintering temperature to obtain the density level necessary to isolate all the pores. Lowering the sintering temperature is very critical to maintain fine microstructure since grain and carbide coarsening are accelerated by higher sintering temperature due to more liquid phase formation. The powders obtained by ball milling at 20 to 1 ratio has the lowest compressibility but has the best sinterability, almost compatible to unmilled pure M2 powders. A sintered body over 97% theoretical density with fine microstructures having average grain size of ~10 microns was obtained from the powder by sintering at 1260 $^{\circ}C$ for 1 hour in vacuum. XRD results indicate that two types of carbides are mainly present in the sintered structure, MC and $M_{6}C$ type. The MC type carbides are more or less round shaped and mainly located at the grain boundaries whereas the $M_{6}C$ type are angular shaped and mainly located inside the grains.

• 패션비즈니스
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• 제19권3호
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• pp.101-112
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• 2015

Because young men's slacks are becoming more slim-fitting today, this study attempts to identify room for improvement by comparing and analyzing the patterns of men's slacks in the literature and those of manufacturers. Selected for the study are two patterns from the literature and one from manufacturers (Slacks A, B, C); those from studies are slim silhouette pants with no tucking around the waist at the front. Subjects for the Fit tests and the pattern designs were men in their twenties with average body shapes in accordance with the figures in Size Korea 2010. Pants were made from muslin fabric and the Fit tests were carried out with three subjects and a panel of five experts to evaluate comfort and appearance. The analysis of the patterns revealed that Slacks A were the longest followed by C and then B. Slacks C had the most girth ease, and Slacks B were the slimmest in both length and girth. Movement tests showed Slacks A to be the most comfortable followed by B and then C. The appearance test found that Slacks B were the most attractive, followed by A, and then C. The fits at the front, back and sides of all three pants were more or less the same. We suggest that more studies be done on pants patterns adjusting them for proper ease and using elastic fabric in order to maintain the slim fit and also to be comfortable to wear.

• 한국의류학회지
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• 제43권2호
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• pp.204-214
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• 2019

A CAD program has recently been introduced that can be directly developed into a three-dimensional human body shape and made into a pattern. It is possible to fabricate a bra that reflects the volume and surface area of the breast; however, it still needs to be verified. This study investigates the average size and shape of 20 big-breasted women and designs a brassiere pattern for women with large breasts using a 3D Flattening function of OptiTex PDS v15.6. In addition, the study verifies the reliability of the proposed method compared to a conventional brassiere pattern. The study results are as follows. First, the three dimensional measurement values were smaller than the direct measurement dimensions when the three dimension measurement dimensions of the subjects were compared with the direct measurement dimensions, the replica measurement dimensions and the three dimensional measurement dimensions. Second, the 3D flattening pattern reflects the actual shape, length, and area of the actual breast when comparing a brassiere pattern using a 3D shape and pattern reflecting the direct measurement.

• Parasites, Hosts and Diseases
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• 제56권5호
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• pp.501-507
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• 2018

We described here the morphological characteristics for the species identification and fish hosts of Isoparorchis sp. (Digenea: Isoparorchiidae) in the Republic of Korea (Korea). Total 1,371 freshwater fishes collected in Yangcheon (Stream) in Sancheong-gun, Gyeongsangnam-do were examined by the artificial digestion methods to survey the infection status of digenetic trematode metacercariae for 4 years (2013-2016). Adult and larval worms of Isoparorchis sp. were detected in 38 (8.4%) out of 451 fish in 4 species, i.e., Pungtungia herzi, Acheilognathus koreensis, Squalidus japonicus coreanus and Odontobutis platycephala, examined. The infection density was 1.1 worm per fish infected. They were mainly found in the subcutaneous tissues and abdominal cavities. Nodules with worms in the subcutaneous tissues were revealed as the blue ink-colored bulges. Adults leaf-like, $21.6{\times}9.84mm$ in average size. The ratio of body length to body width was 2.20: 1. Oral sucker subterminal, $1.03{\times}1.22mm$. Pharynx muscular, $0.55{\times}0.54mm$. Esophagus very short. Ceca convoluted, terminated near the posterior end. Ventral sucker anterior 1/3.75, $1.99{\times}2.10mm$. The ratio of ventral sucker to oral sucker was 1.74: 1. Testes round to elliptical, both sides of ventral sucker, $1.43{\times}1.33mm$. Vitellaria highly dendritic, posterior 1/3 level. Eggs operculated, embryonated, $52{\times}32{\mu}m$ in size. By the present study, 4 fish species aforementioned are to be listed as the fish hosts of Isoparorchis sp. in Korea and additionally the morphological characteristics are to be described for the species identification.

• 한국의류산업학회지
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• 제13권5호
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• pp.759-768
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• 2011

This study is designed to understand current wearing conditions of air force mechanic parkas and evaluate their functionality by examining the wearing conditions and wearers' subjective assessment. By doing so, it also intends to identify issues that require improvements; and to provide basic data for future development of air force mechanic parkas. A survey was conducted as a study methodology, and the collected 1,628 questionnaires were analyzed. Findings of this study are as follows. 1. In the usability assessment, it was found that visibility of body sides was needed to be enhanced since reflective tapes were attached only to the front and back of the body; pockets were too big, but not convenient to keep mechanic tools; the design of hiding hood was not suitable for water-proof clothing; and a new design of size-controllable hood was called for since the hood blocked eye sight. With respect to the fabric, dissatisfaction was identified with durability, cold-proof and fire-proof features. 2. In the mobility assessment, respondents showed low satisfaction with collar heights and neck girths. Mobility score was over moderate level on average, except the parka length that obstructs wearers' movement, and neck and collar size. 3. In the wearability assessment, respondents presented moderate satisfaction with pleasantness, weight, pressure and dampness. However, insulation was found unsatisfactory. Based on the result, this study proposed improvement plans on design, pattern and fabric; and is expected to serve as basic data for developing more effective and functional air force mechanic parkas.

• 대한인간공학회지
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• 제35권6호
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• pp.581-594
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• 2016

Objective: The purpose of this study is to develop an all- in-one collar shirt with excellent appearance which is well suited to the body shape of the male adults. Background: As men's casual wear has recently become more casual and the number of cool biz wearing in the summer has increased, a variety of shirt colors have been preferred in addition to shirt collar. However, studies on the design and pattern development of men's casual shirt collars are very rare. So we have identified the necessity of various development and research of men's shirts. Method: We collected 8 all-in-one collar patterns for shirts from professional pattern books and men's shirt brands. Also, based on anthropometric data from the 6th Size Korea, we selected 5 subjects with measurements similar to the average adult men, manufactured shirts based on them and conducted a wearing test by 5 experts. Results: After selecting shirts with good fit and appearance, we developed a prototype of all-in-one collar. As for front appearance evaluation, E1 pattern had the most outstanding shape and size, and C1 pattern had the most natural creases and front adjustment curves. As for side appearance evaluation, C1 had the highest overall scores, and E1 pattern on outer line. As for back appearance evaluation, C1 pattern had the highest score. Conclusion: We suggested new all-in-one collar and shirt patterns. In addition, the prototype of the all-in-one collar shirt design was presented by reflecting results of the wearing test and preference survey. Application: The shirt's design and patterns could be manufactured using the developed patterns. It will fit well with the body shape of adult males and will be highly satisfied by them.