• Title/Summary/Keyword: available life

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In silico Identification of SFRP1 as a Hypermethylated Gene in Colorectal Cancers

  • Kim, Jongbum;Kim, Sangsoo
    • Genomics & Informatics
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    • v.12 no.4
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    • pp.171-180
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    • 2014
  • Aberrant DNA methylation, as an epigenetic marker of cancer, influences tumor development and progression. We downloaded publicly available DNA methylation and gene expression datasets of matched cancer and normal pairs from the Cancer Genome Atlas Data Portal and performed a systematic computational analysis. This study has three aims to screen genes that show hypermethylation and downregulated patterns in colorectal cancers, to identify differentially methylated regions in one of these genes, SFRP1, and to test whether the SFRP genes affect survival or not. Our results show that 31 hypermethylated genes had a negative correlation with gene expression. Among them, SFRP1 had a differentially methylated pattern at each methylation site. We also show that SFRP1 may be a potential biomarker for colorectal cancer survival.

Synthesis and SAR of Methoxyiminoacetate and Methoxyiminoacetamide Derivatives as Strobilurin Analogues

  • Hwang, In-Cheon;Kim, Joo-Kyung;Kim, Hyung-Ho;Kyung, Suk-Hun
    • Bulletin of the Korean Chemical Society
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    • v.30 no.7
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    • pp.1475-1480
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    • 2009
  • Methoxyiminoacetate and methoxyiminoacetamide derivatives possessing 2,2-dichlorovinyl side chains, have been synthesized and their biological activities against six representative plant fungal pathogens have been evaluated. Five substances in this series (3a, 4a, 3b, 3d, and 4d) were found to exhibit potent fungicidal activities compared to those of the commercially available fungicides, azoxystrobin and fenarimol.

Antioxidative Effect of Histidine and Alanine on Oil Rancidity (Histidine과 Alanine의 유지에 대한 항산화 효과)

  • 조희숙
    • Journal of the East Asian Society of Dietary Life
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    • v.9 no.1
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    • pp.93-99
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    • 1999
  • The purpose of this study was to investigate the antioxidant and synergistic effects upon different concentrations(0.02, 0.1, l%) of histidine and alanine in soybean oil during incubation at 6$0^{\circ}C$. Acid value(AV), peroxide value (POV) and thiobarbituric acid(TBA) value of each oil was monitored. Histidine and alanine showed antioxidative effects in all concentrations. In the case of the incubating antioxidative effect of histidine was lower than that of TBHQ. That of alanine was considerably higher than that of $\alpha$-tocopherol, but was lower than that of histidine. Synergistic effects among histidine, alanine and some food antioxidants were shown to exist available in all substrates and the best effect was shown in substrate added compound of histidine and $\alpha$-tocopherol.

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Experimental Study on the Cooling seasonal Performance Factor of Room Air-conditioner (에어컨의 냉방기간 에너지 효율 산출을 위한 실험적 연구)

  • Lee, H.W.;Moon, J.H.;Bae, Y.D.;Park, J.C.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.4 no.3
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    • pp.204-216
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    • 1992
  • In most cases, EER(Energy Efficiency Ratio) is available to present energy efficiency of air-conditioners. But, EER is not adapt to measure energy efficiency at actual life environment because it is based on fixed temperature and humidity contditions. To overcome this disadvantage, there is need to introduce SEER(Seasonal Energy Efficiency Ratio) established at time varient temperature and humidity conditions. In this paper, SEER measurement method and conditions based on actual life environment of the country is introduced, and discussed SEER value about two air-conditioner type, that is, non inverter air-conditioner and inverter air-conditioner. As a result of, inverter air-conditioner was superior to non inverter air-conditioner at cooling seasonal energy efficiency.

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Properties of Electrical Performance on Stator Coil of Traction Motor by Accelerated Test (견인전동기 고정자 코일의 전기적 열화특성)

  • Park Hyun-June;Jang Dong-Uk;Kim Gil-Dong
    • Proceedings of the KSR Conference
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    • 2003.10c
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    • pp.623-627
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    • 2003
  • Aging and failure of motor insulation depend on the stresses imposed on it. The insulation life time depends on the severity of the stresses. The electrical aging by transient surge is very important to traction motor in EMU(electric multiple unit). This paper presents the insulation characteristics of stator coil by transient surge from inverter. There are several nondestructive tests available for checking the condition of motor insulation, the probable extent of aging, and the rate of which aging is taking place. So the insulation characteristics of stator coil were each analyzed by measurement of leakage current, dielectric loss($tan{\delta}$), capacitance, polarization index(PI) and partial discharge. The method of diagnosis is able to analyze the aging condition and predict the life of the traction motor in EMU.

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Separation of Tetrodotoxin, DHA and EPA from Pufferfish Liver Waste (복어간 폐기물로부터 Tetrodotoxin, DHA 및 EPA의 분리)

  • 차병윤;최진석;임정규;이동익;이원갑;이은열;김희숙;김동수
    • Journal of Life Science
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    • v.10 no.2
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    • pp.115-124
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    • 2000
  • The present study was undertaken to separate the available components effectively, such as tetrodotoxin(TTX), docosahexaenoic acid(DHA, C22:6,ω-3) and eicosapentaenoic acid (EPA, C20:5,ω -3) from pufferfish liver waste, which are known to have high values as bioactive materials. By using ultrafiltration, it was possible to separate high contents of 68mg TTX from pufferfish liver waste. In contrast, by activated charcoal column, it was to obtain about 54mg TTX. The recovering ratios were 65.3% and 45.0% in the two different methods of ultrafiltration and activated charcoal column, respectively. From the results of HPLC and gas chromatography-mass spectrometry(GC-MS), the obtained toxins were identified to be TTX and its derivatives. In addition, it was also possible to obtain 72.3g DHA and 11.4g EPA from 1kg of pufferfish liver by high performance liquid chromatography (HPLC). These amounts of DHA and EPA were also 17.70% and 1.04% in the total lipid of pufferfish liver oil from analysis of gas chromatography(GC), respectively.

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Properties of Electrical Performance by Inverter Surge on Stator Coil of Traction Motor (인버터 서지에 의한 견인전동기 고정자 권선의 전기적 특성 변화)

  • Park, Hyun-June;Jang, Dong-Uk;Choi, Nam-Ho;Choi, Jong-Sun;Kim, Jung-Soo
    • Proceedings of the KIEE Conference
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    • 2003.07b
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    • pp.1285-1287
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    • 2003
  • The aging of the insulation reduces the electrical and mechanical strength of the insulation. At same point, a voltage surge or mechanical shock from a traction motor start will fracture or break down the insulation. To achieve the expected life usually requires extensive laboratory evaluation of the insulation systems and the use of accelerated aging tests. There are several nondestructive test available for checking. the condition of motor insulation, the probable extent of aging, and the rate of which aging is taking place. So the insulation characteristics of stator coil were each analyzed by measurement of dielectric loss($tan{\delta}$), capacitance and partial discharge. The method of diagnosis is able to analyze the aging condition and predict the life of the traction motor.

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Park Management with Citizen Participation under an Initial Council Style Scheme - Case Study of Hyogo Prefectural Arimafuji Park -

  • Mari Fujimoto;Isao Nakase;Ryuko Kobayashi;Yukihiro Kadono
    • Journal of the Korean Institute of Landscape Architecture International Edition
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    • no.2
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    • pp.206-209
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    • 2004
  • A requirement of park management is to transfer the focus from emphasizing the management of public materials to providing services to visitors. Therefore, it has become indispensable to create a scheme in which residents can take management initiative. At this time, we look at Hyogo Prefectural Arimafuji Park, which encourages citizen management participation, and try to understand their system and project contents. For an initial scheme, we identify 4 elements that promoted subjective participation in a council style scheme; 1. to begin activities at the earliest possible time before opening the park, 2. to coordinate with expert(s) who take a neutral position, 3. to have places available where participants can debate on an equal footing, and 4. to plan the project while feeding back actual results.

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Development of A Pilot Android Application for Location-based Mobile Agricultural Information System (위치기반 모바일 농업정보시스템 구축을 위한 안드로이드 애플리케이션 시험 개발)

  • Kim, Sang Min;Jang, Min-Won
    • Journal of Korean Society of Rural Planning
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    • v.20 no.4
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    • pp.277-284
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    • 2014
  • Recently the use of smart phones and mobile devices is increasing rapidly, data search and retrieval in the mobile environments are generalized. There are only few mobile applications available in the area of agriculture while huge amount of new applications are developed and uploaded. The purpose of this study was to develop the android based mobile application for providing agricultural infrastructure and disaster information. The mobile application was designed through the database establishment and management system, server management system, and mobile application development. The database is composed of weather data, agricultural infrastructure data, and agricultural disaster data. By developing the mobile application which provides agricultural infrastructure information, it is expected to improve the accessibility to agricultural information and mitigate the agricultural disaster damages.

Review of dexamethasone administration for management of complications in postoperative third molar surgery

  • Selvido, Diane Isabel;Bhattarai, Bishwa Prakash;Niyomtham, Nattisa;Riddhabhaya, Apiwat;Vongsawan, Kadkao;Pairuchvej, Verasak;Wongsirichat, Natthamet
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.47 no.5
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    • pp.341-350
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    • 2021
  • Dexamethasone has been used in oral and maxillofacial surgery for postoperative pain, swelling, and trismus following third molar surgeries. It is a potent and powerful drug that can alleviate the aforementioned postoperative sequelae. Dexamethasone is responsible for inhibiting the release of inflammatory mediators in the inflammation process to improve patient quality of life after surgical intervention. There are several available routes of administering dexamethasone. This article will help determine the suggested routes of administration, dosage, parameters, and dexamethasone timing for third molar surgeries.