• Journal of Radiation Industry
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• v.5 no.4
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• pp.313-316
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• 2011

[$^{18}F$]FDG (2-[$^{18}F$] Fluoro-2-deoxy-D-Glucose), which is required Automated Synthetic Module for production, is most often used Radiopharmaceuticals in nuclear medicine. In this study, an Automated Synthesis Module was developed to produce FDG in two consecutive time when F-18 feds continuously by modifying a domestic FDG Automated Synthetic Module on structural geometry and control system. The results were showed that the Average Synthesis Yields on the developed Automated Synthetic Module were $45{\pm}3%$ (n=20), $50{\pm}3%$ (n=20) respectively. The Quality Control results, such as Radio TLC, Radiochemical purity, Gamma-counter, pH, LAL Test, Micro bacteria test, showed in same level with domestic [$^{18}F$]FDG Auto-Synthetic modules. Therefore, if some features were improved by considering the components life time and appearance, commercial sales can be expected because of low price and easy maintenance compared with foreign products.

• Journal of Ship and Ocean Technology
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• v.5 no.1
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• pp.14-29
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• 2001

Concept and preliminary structural design methods, including large scale FEM analysis and optimisation, for large passenger ships, car passenger and RoRo/ passenger ships are dis-cussed. Applications and experiences in practical design usage are presented.

• The Journal of Engineering Research
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• v.4 no.1
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• pp.35-45
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• 2002

This paper deals with the scheduling problems which are the most important subtask in High-Level Synthesis. Especially, we have concentrated our attentions on the data-path scheduling which can get the structural informations from the behavioral algorithm as a first step in synthesis procedure. Suggest Forward scheduling methode is executed the ASAP and ALAP scheduling to use the fifth – order elliptic wave filter of a standard benchmark model, and then it is drawing up T.N matrix table by the number of resource and control-step, using the table extract of the simple than down-limit value of the control-step for the number of given resource to use this table. All of existing list scheduling techniques determine the priority functions first, and then do the operation scheduling, But, the suggested forward scheduling technique does the schedule first, and determines the priority functions if needed in scheduling process.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1999.10a
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• pp.143-150
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• 1999

The LRFD Specification defines two sets of limiting width-to-thickness ratios. On the basis of these limiting values, steel sections we subdivided into three categories: compact, noncompact, and slender sections. A compact section is capable of developing a fully plastic stress distribution (plastic moment), and can sustain rotations approximately three times beyond the yield before the possibility of local buckling arises. Noncompact sections can develop the yield stress before local buckling occurs. They may not, however, resist local buckling at the strain levels required to develop the fully plastic stress distribution. In this paper, 1-Type girders of a 2 span continuous steel bridge are divided into compact and non-compact sections and analyzed. In the design process, an optimization skill was adopted and ADS, a Fortran program for Automated Design Synthesis, was used.

• Nuclear Engineering and Technology
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• v.40 no.5
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• pp.365-374
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• 2008

Dependability-critical systems, such as digital instrumentation and control systems in nuclear power plants, necessitate engineering techniques and tools to provide assurances of their safety and reliability. Determining system reliability at the architectural design phase is important since it may guide design decisions and provide crucial information for trade-off analysis and estimating system cost. Despite this, reliability and system engineering remain separate disciplines and engineering processes by which the dependability analysis results may not represent the designed system. In this article we provide an overview and application of our approach to build architecture-based, dynamic system models for dependability-critical systems and then automatically generate dynamic fault trees (DFT) for comprehensive, tool-supported reliability analysis. Specifically, we use the Architectural Analysis and Design Language (AADL) to model the structural, behavioral and failure aspects of the system in a composite architecture model. From the AADL model, we seek to derive the DFT(s) and use Galileo's automated reliability analyses to estimate system reliability. This approach alleviates the dependability engineering - systems engineering knowledge expertise gap, integrates the dependability and system engineering design and development processes and enables a more formal, automated and consistent DFT construction. We illustrate this work using an example based on a dynamic digital feed-water control system for a nuclear reactor.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1998.04a
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• pp.262-271
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• 1998

Recent, more and more steel deck bridges are adopted for the design of long span bridges and the upgrading of existing concrete deck bridges, mainly because of reduced self weight, higher stiffness and efficient erection compared to concrete decks. The main objective of this study is to propose on formulation of the design optimizations to develop an optimal desist program required for optimum desist for orthotropic steel-deck bridges. The objective function of the optimization is formulated as a minimum initial cost design problem. The behavior and design constraints are formulated based on the ASD and LRFD criteria of the Korean Bridge Design Code(1996). The optimum design program developed in this study consists of two steps. In the first step the system optimization of the steel box girder bridges is carried out. And in the second step the program provided the optimum design of the orthotropic steel-deck with close ribs. In the optimal design program the analysis module for the deck optimization is based on the Pelican Esslinger method. The optimizer module of the program utilizes the ADS(Automated Desist Synthesis) routines using the optimization techniques fuor constrained optimization. From the results of real application examples, The cost effectiveness of optimum orthotropic steel-deck bridges designs based on both ASD and LRFD methods is investigated by comparing the results with those of conventional designs, and it may be concluded that the design developed in this study seems efficient and robust for the optimization of orthotropic steel-deck bridges

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.3
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• pp.31-38
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• 2010

In this study, it is suggested that it has to reliability-based design methodology with respect to bridge structure-rail longitudinal interaction and bridge structure-vehicle interaction. For the structural analysis, commercial package, ABAQUS, are used for a three-dimensional finite element analysis. The optimization process utilizes a well-known optimizer, ADS(Automated Design Synthesis). Optimization technique is utilized the ALM-BFGS method for global area search and Golden Section Method for 1-D search. In general, ALM-BFGS method don't need the 1-D search, and that algorithm converge a 0.1~0.2 of Push-Off factor. But in this study, value of Push-Off factor is used 90, therefore 1-D search should be needed for effective convergency. That algorithm contains the "heuristic decision method". As a result of optimum design of 2-main steel girder birdge with 5${\times}$(1@50m), design methodology suggested in this study was demonstrated more economic and efficient than existing design and LCC optimization not considering bridge-rail longitudinal interaction and bridge-vehicle interaction.

• Korean Journal of Radiology
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• v.22 no.6
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• pp.983-993
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• 2021

Objective: To investigate the image quality of ultralow-dose CT (ULDCT) of the chest reconstructed using a cycle-consistent generative adversarial network (CycleGAN)-based deep learning method in the evaluation of pulmonary tuberculosis. Materials and Methods: Between June 2019 and November 2019, 103 patients (mean age, 40.8 ± 13.6 years; 61 men and 42 women) with pulmonary tuberculosis were prospectively enrolled to undergo standard-dose CT (120 kVp with automated exposure control), followed immediately by ULDCT (80 kVp and 10 mAs). The images of the two successive scans were used to train the CycleGAN framework for image-to-image translation. The denoising efficacy of the CycleGAN algorithm was compared with that of hybrid and model-based iterative reconstruction. Repeated-measures analysis of variance and Wilcoxon signed-rank test were performed to compare the objective measurements and the subjective image quality scores, respectively. Results: With the optimized CycleGAN denoising model, using the ULDCT images as input, the peak signal-to-noise ratio and structural similarity index improved by 2.0 dB and 0.21, respectively. The CycleGAN-generated denoised ULDCT images typically provided satisfactory image quality for optimal visibility of anatomic structures and pathological findings, with a lower level of image noise (mean ± standard deviation [SD], 19.5 ± 3.0 Hounsfield unit [HU]) than that of the hybrid (66.3 ± 10.5 HU, p < 0.001) and a similar noise level to model-based iterative reconstruction (19.6 ± 2.6 HU, p > 0.908). The CycleGAN-generated images showed the highest contrast-to-noise ratios for the pulmonary lesions, followed by the model-based and hybrid iterative reconstruction. The mean effective radiation dose of ULDCT was 0.12 mSv with a mean 93.9% reduction compared to standard-dose CT. Conclusion: The optimized CycleGAN technique may allow the synthesis of diagnostically acceptable images from ULDCT of the chest for the evaluation of pulmonary tuberculosis.