• 한국환경보건학회지
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• 제37권3호
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• pp.193-200
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• 2011

Objective: The purpose of this study is to compare and analyze the level of exposure to volatile organic compounds for different kinds of households in apartments or houses and analyze the relation between atopy-related symptoms and concentration of volatile organic compounds in order to improve indoor air quality and start to build a process to prevent environmental diseases. Method: From July 2010 to November 2010, TVOC concentration levels were measured and analyzed in 402 general households and 236 weak households, totalling 638 households. Residents were asked to fill out a survey on environmental disease. All resources were analyzed using SPSS 12.0 program. Result: In comparing the differences in concentration levels of volatile organic compounds for different types of households, including existing apartments and houses, the type of housing did not affect the concentration level of volatile organic compounds, but the relevance with skin trouble, diagnosed atopy, and atopy systems all had statistical similarities. Moreover, above-limit volatile organic compounds showed statistical relevance with amount of ventilation, time of construction, skin trouble, diagnosed atopy and atopy symptoms. Conclusion: The study concludes that as the time of construction recedes further into the past and as the amount of ventilation is higher, the exposure level to volatile organic compounds was lower and the group that were suffering from atopy symptoms had higher exposure to volatile organic compounds.

• 한국식품영양학회지
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• 제18권4호
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• pp.380-384
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• 2005

2004년 10월부터 2005년 9월까지 대전 선골한의원에 아토피를 주 증상으로 내원한 환자 총 36명을 대상으로 증상에 따라 1개월에서 12개월 동안 복용하도록 한 후 몇 가지 일반상황 및 한방 추출물 복용 전후의 아토피 증상 호전도 등을 조사하였다. 환자 중 남녀의 성비는 61.11:38.89이었으며, 연령별 분포는 20세 이하가 18명으로 전체 환자수의 $50\%$를 차지하는 것으로 나타나 성인기, 노인기보다는 유년 및 청년기에 아토피 환자가 더 많은 것을 알 수 있었다. 아토피 증상이 호발하는 부위로는 다리와 사타구니가 $25.88\%$로 가장 많았으며, 그 다음이 팔과 목, 얼굴로 각각 $22.35\%,\;16.47\%,\;14.12\%$였고, 겨드랑이가 $2.35\%$로 가장 낮았으며 아토피가 나타나는 부위 중 한 개 혹은 두 개 이상의 부위를 가지고 있는 환자수를 조사한 결과 $50\%$이상의 환자가 3가지 이상의 아토피 호발 부위를 가진것으로 나타났다. 아토피 환자에게 한방 추출액을 복용시킨 결과 복용 전 환자들은 $72.22\%$가 중증도의 홍박과 $63.8\%$가 경도의 부종과 $44.44\%$의 경도 찰상을 보유하고 복용후 홍반과 부종, 찰상이 각각 경도 ($55.56\%$), 경도($52.78\%$), 없음($83.33\%$)으로 복용전보다 호전된 것을 알 수 있었다.

• 대한예방한의학회지
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• 제24권2호
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• pp.71-82
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• 2020

Objectives : The purpose of this study is to evaluate clinical utilization by measuring compliance with the use of mobile health applications (AtopyPHR developed in a previous study) for patients with atopic dermatitis. Methods : Based on the AtopyPHR and the input period and frequency survey results for each symptom item, a scenario for measuring compliance was derived. The study period was 4 weeks. Participants installed AtopyPHR app and Telegram app on their smartphones, conducted user training on the app, and recorded symptoms using the app for 4 weeks. At the 2nd and 4th week visits, the AtopyPHR data recorded by the user can be viewed on the web page and used for medical decision. Compliance was analyzed by the date the symptoms were recorded. Results : There were 28 participants, all (100%) were compliant, and the compliance was 96.8. The patients were 1 to 18 years old, and the average age was 8.2±5.7 years, 10 males and 18 females. The actual date of participation in recording symptoms was 28.6±0.56 on average. Compared to Week 1, compliance decreased at Week 2, and Week 4 had the highest compliance. Daily check, daily emotion, stool/urine/sleep, and meal management showed high compliance, SCORAD and quality of life were higher than required to record. Conclusions : AtopyPHR was effective in compliance. The results of this study could be used to collect personal health data in daily life through the AtopyPHR, improving participant compliance. It is considered to be meaningful because it measured the compliance with the symptom record actually recorded using the mobile app rather than a questionnaire. This study may be useful not only for personal health care but also for medical decisions, as opinions are given by experts who treat atopic dermatitis.

• Environmental Analysis Health and Toxicology
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• 제27권
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• pp.6.1-6.8
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• 2012

Objectives: Childhood allergic diseases are a major concern because they lead to a heavy economic burden and poor quality of life. The purpose of this study was to investigate the prevalence of childhood atopic dermatitis, asthma, allergic rhinitis, and the comorbidity of allergic diseases in Seoul, Korea. Methods: We conducted a cross-sectional survey between May and October 2010 to evaluate the prevalence of childhood allergic diseases, including atopic dermatitis, asthma, and allergic rhinitis, using a questionnaire from the International Study of Asthma and Allergies in Childhood group. Each questionnaire was completed by the parent or guardian of a child. Results: In the 31,201 children studied, the prevalence of atopic dermatitis symptoms in the past 12 months was 19.3% in children 0 to 3 years of age, 19.7% in children 4 to 6 years of age, 16.7% in children 7 to 9 years of age, and 14.5% in children 10 to 13 years of age (p for trend < 0.001). The prevalence of asthma in these age groups was 16.5%, 9.8%, 6.5%, and 5.4%, respectively (p for trend < 0.001). The prevalence of allergic rhinitis in these age groups was 28.5%, 38.0%, 38.5%, and 35.9%, respectively (p for trend = 0.043). The percentage of subjects with both atopic dermatitis and asthma, both asthma and allergic rhinitis, or both atopic dermatitis and allergic rhinitis was 2.5%, 4.7%, and 8.7%, respectively. The prevalence of comorbid allergic diseases decreased with age (p for trend < 0.001). Conclusions: Our study revealed that the prevalence of some allergic diseases, such as atopic dermatitis and asthma, was relatively high in very young children and that all of the principal allergic diseases in children often co-exist.

• 한국생활과학회:학술대회논문집
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• 한국생활과학회 2008년도 하계학술대회
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• pp.153-154
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• 2008

• 한국안광학회지
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• 제17권4호
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• pp.457-467
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• 2012

목적: 오래된 건물에 비해 환경 오염 물질이 많이 방출될 것이라 여겨지는 신축된 초등학교에 다니고 있는 어린이들의 눈 자각 증상과 알레르기 증상의 관련성에 대해 알아보았다. 방법: 수도권에 위치하고 있으며 신축한지 3개월이 지난 초등학교에서 수업을 듣는 6학년 115명(남학생 54명, 여학생 61명)을 대상으로 dry eye questionnaire(DEQ)와 ocular surface disease index(OSDI)를 이용하여 건성안과 전반적인 눈 증상에 대해 자각 증상을 설문하였다. 알레르기 관련 설문은 아토피와 알레르기 비염의 과거력을 조사하였고, allergic rhinitis impacts on asthma(ARIA) 지침의 알레르기 비결막염 설문을 사용하여 코간지러움과 눈증상에 대해 10점 척도의 visual analog scale로 체크하였다. 결과:DEQ의 설문 조사에서 57명(50%)의 학생이, OSDI식 설문 조사에서는 19명(16.52%)의 학생이 건성안으로 진단되었으며, 두 가지 설문에서 모두 건성안으로 진단된 학생은 18명(15.79%)으로 조사되었다. 아토피와 알레르기 비염을 가지고 있는 학생은 각각 45명(39.5%)과 29명(25.4%)이었다. 아토피를 가지고 있는 학생 중 건성안을 보인 학생은 DEQ를 이용했을 때 30명, OSDI를 이용했을 때 8명이었다. 또한 알레르기 비염을 가지고 있는 학생 중 건성안을 보인 학생은 DEQ을 이용했을 때 22명, OSDI를 이용했을 때 5명이었다. 아토피와 비염 모두 과거력이 있는 29명의 학생 중에 15명이 눈에 자극을 자각하였다. 눈에 자극과 함께 중복으로 자각하는 알러지 증상으로는 재채기, 코 간지러움, 코 막힘, 콧물의 순서로 많이 나타났으며, 눈에 자극을 자각한 학생일수록 중복하는 알레르기 수와 학생 수가 비례적으로 증가하였다. 결론: 신축된 학교 건물과 같은 환경에서 생활하는 어린이들의 눈 건강 상태에서 눈의 자극 증상이 조사되었으며, 아토피나 알레르기 비염 증상을 가진 학생들에게서 건성안 증상 호소가 더 많은 것을 확인할 수 있었다.

• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.230-239
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• 2007

Introduction : Atopic dermatitis is very epidermic disease in these days. Atopic dermatitis is difficult for patient to be treated because there is no specific treatment. The oriental method of atopic dermatitis is varied as patient situation and doctor's view point. The Treatise on Febrile Diseases(傷寒論) may be a hint for atopy disease. Object: Although we use various method such as acupucture, aroma therapy, a medicine for external use, we use the two decoctions in the Treatise on Febrile Diseases according to differentiation of syndromes and abdominal diagnosis. Result : After inpatient treatment in 21 days, the itching, redness, exudation, crust, lichen get better and insomnia and constipation was removed quickly. The SCORAD index is decreased from 84.2 to 25.9. Conclusion : These decoction can treat the atopic dermatitis although there is no symptom in atopy because we cure the all situation of the patient. We can cure the atopic dermatitis not only by routine remedy for various symptoms but also by diagnosis and treatment based on overall analysis of symptoms and signs.

• 한국식생활문화학회지
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• 제29권5호
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• pp.380-389
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• 2014

The aim of this study was to investigate the relationship between intake experience of mother's milk intake/baby food intake, present eating habits, and atopy symptoms in elementary school students in Chungnam province. More frequent intake of mother's milk was associated with less atopy symptoms. Subjects who had good attitudes for baby food in the past had less unfavorite foods. In addition, subjects that ate fruits and vegetable-baby food had better eating attitudes for a balanced diet. Unbalanced diet was associated with worse behavior characteristics. Frequency of eating breakfast affected behavioral characteristics. As this study had regional and size limitations, it is necessary to further investigate the relationship between past intake experience of mother's milk/attitude towards baby foods and present eating habits/physical growth. Based on these results, past intake experience of mother's milk/attitude towards baby foods might affect present physical growth/development and eating habits of subjects.

• 한국생활과학회지
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• 제24권1호
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• pp.123-135
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• 2015

In order to examine allergic disease experience rates of students at atopy and asthma friendly elementary schools located in Chungcheongnam-do and investigate their dietary behaviors, a survey on 250 parents of first to third grade students at four rural-type atopy and asthma friendly elementary schools was conducted. The number of students who had experienced allergic symptoms (allergic group) was 102 (40.8%). their breastfeeding duration was shorter than that of the non-allergic group (p<.001) and the former's weaning foods-feeding had started earlier than the latter's (p<.01). Regarding the eating habits, the non-allergic group was found to have breakfast and dinner better than the allergic group (p<.001). The number of students eating fruits as snacks was largest in the allergic group at 73 (71.6%), and as for the non-allergic group, their rate of eating fruits, milk and dairy products, and cookies and fries was at 25.7%, 22.3%, and 20.3%, respectively. A high percentage of the allergic group ate three times or less per month the animal food groups and dairy products (p<.001). Accordingly, for improvement in dietary behaviors of students who have allergy against food, nutrition education on regular eating, balanced intake of food, adequate intake of snacks and meals for proper growth and development and precise diagnosis of allergy-triggering food are necessary. In particular, as education on food allergy, implementation of practical education such as appropriate nutrition counseling by nutrition teachers is urgent beyond the one-way educational method of school newsletters.

• Clinical and Experimental Pediatrics
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• 제56권5호
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• pp.191-195
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• 2013

Severe childhood asthma is a complicated and heterogeneous disorder with distinct phenotypes. Children with severe asthma have more persistent symptoms despite receiving treatment, more atopy, greater airway obstruction, and more air trapping than those with mild-to-moderate asthma. They also have higher morbidity and substantial airflow limitations that persist throughout adulthood. Identification of the phenotype clusters and endotypes of severe asthma can allow further modulation of the natural history of severe asthma and may provide the pathophysiologic rationale for appropriate management strategies.