• Journal of Environmental Health Sciences
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• v.47 no.5
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• pp.472-478
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• 2021

Background: The Legionella case detection and notification rate have increased in public artificial water environments where people visit, including large buildings, public baths, and hospitals. Objectives: In this study, the distribution of Legionella and its epidemiologic characteristics were analyzed in the water systems of public facilities in Chungcheongnam-do Province in South Korea. Methods: Culture and PCR analysis were performed on 2,991 environmental water system samples collected from 2017 to 2019, and associations with year, facilities, seasons, and temperature of water system were statistically analyzed by using R-Studio for Windows. Descriptive data was compared using chi-square tests and independent t-tests. Results: The detection rate of Legionella increased from 3.1% in 2017 to 10.3% in 2019, appearing most frequently in the order of public baths, large-scale buildings, hospitals, and apartments. It was detected mainly in summer from June to August, over 1.0×10³ CFU/L on average in 133 cases (66.5%). Lots of germs were detected in bathtub water, cooling tower water, and warm water (p<0.001), and it was detected at higher rates in the cities where multipurpose facilities were concentrated than in rural areas (p=0.018). Conclusions: This study suggests that continuous monitoring and control are required for Legionella in the water system environment of high risk facilities. Moreover, these results will be helpful to prepare efficient management plans to prevent the Legionellosis that occurs in Chungcheongnam-do Province.

• Journal of Information Technology Applications and Management
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• v.28 no.6
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• pp.69-85
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• 2021

In the era of the 4th Industrial Revolution, not only artificial intelligence, big data, robots, and biotechnology, but also cultural industries that require human creativity will lead. Among the cultural industries, the animation industry has high industrial utilization value due to its high connection with other industries. Among them, animation characters play the most important role as the subject leading the story of animation. In particular, the villain character not only serves as a medium for the main character to lead the story, but also captivates the audience with a different presence from the main character, adding to the fun and completeness of the animation. These characters consist of visual elements such as form and color, of which color is a tool that effectively conveys the character's personality and role to the audience, and is the first visual element to be considered in delicately describing the character's emotions and the relationship between characters. Therefore, this study attempts to analyze the color of the villain character. To this end, we will select eight Disney animations to derive the characteristics of the villain character's color by analyzing the color, value, chroma, and color association of the colors used in the Disney villain character. As a result of the analysis, the colors mainly used by Disney to convey the villain's image were red (R) and Orange (YR), and there was no difference depending on the times or animation production methods. Second, the brightness of Disney villain characters appeared to be the same medium/famous regardless of the times and production methods, and the frequency of use of high brightness was very low. In terms of saturation, the frequency of use of high and low saturation was high. Third, blackish (Bk), Strong (S), dull (Dl), and deep (Dp) tones were mainly used for tones. In particular, in recent 3D animations than previously produced 2D animations, the use of low chroma and the high black mixing rate increased. Fourth, it can be seen that Disney uses color as a visual method to more clearly express the psychology of the villain character using color association. In conclusion, the color selection of animation characters should be carefully considered as a tool to convey the character's personality, role, and emotion beyond simply using color, and the color selection of characters using color associations and symbols strengthens the narrative structure. It is hoped that this study will help analyze and select the character color of animation.

• Health Policy and Management
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• v.31 no.4
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• pp.462-471
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• 2021

Background: The purpose of this study was to identify the association between participation in social activities and mortality rates for those aged 45 aged and older in Korea. Methods: In this study, the 1st to 6th Korea Longitude Study of Aging was used to analyze 10,217 people excluding missing values among middle and old age groups aged 45 or older. The scope of social activities was classified into "religious gatherings," "religious gatherings," "leisure/cultural/sports-related organizations," and "clubs/hometowns/religious associations," and analyzed using a chi-square test and Cox proportional risk model. Results: In the case of non-participating groups in religious activities, the mortality rate was 1.24 times higher (hazard ratio [HR], 1.24; p=0.000) than those of the participating group. The non-participating group of social gatherings had a 1.27 times higher mortality rate (HR, 1.27; p<0.0001) than the participating group. In addition, the mortality rate of non-participating groups related to leisure/cultural/sports was 1.79 times higher (HR, 1.79; p=0.000). The mortality rate of the group that did not participate in the alumni association/festival/folklore society was 1.51 times higher than that of the participating group (HR, 1.51; p<0.0001). As a result of correcting the control variable to analyze the relationship between the number of participants in social activities and the mortality rate, the mortality rate of the group participating in one or less social activities was 2.26 times higher (HR, 2.26; p<0.0001) compared to the four or more social activity participating groups, and the mortality rate of the 1-3 social activities was 1.64 times higher (HR, 1.64; p<0.0001). Conclusion: As a result of the study, it was found that participation in social activities of the middle-aged and elderly groups was effective in reducing mortality, and in particular, it was found that there was a strong relationship with mortality in less than one social activity group. Therefore, it is intended to provide an academic basis for lowering the mortality rate of the group in line with the continuous improvement of domestic social activity participation conditions, and through this, this study can be expected to serve as a policy and institutional basis for lowering the mortality rate of the group.

• Journal of Korean Elementary Science Education
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• v.40 no.3
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• pp.366-389
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• 2021

The purpose of this study is to extract the factors that compose the image of science teacher desired by elementary school students in inquiry-based instruction and analyze the structural associations between them. Factors that compose the image of science teacher desired by elementary school students in inquiry-based instruction were extracted through exploratory factor analysis (EFA). Based on the findings of EFA, the questionnaire has been further analyzed using confirmatory factor analysis (CFA). In addition, based on the factor structure identified through factor analysis, we comprehensively analyzed the image of science teacher desired by elementary school students in inquiry-based instruction. As a result of EFA, five factors were identified which compose the image of science teacher desired by elementary school students in inquiry-based instruction: namely, teaching strategy, assessment strategy, prior guidance, understanding students, learning development. The CFA results showed a relatively strong correlation between teaching strategy and learning development, teaching strategy and understanding students. As a result of a comprehensive review of students' perception of the image of science teachers in inquiry-based instruction based on the extracted factor structure, students perceived that it is important for science teachers to run inquiry-based instruction by reflecting their understanding of students. Students also perceived importantly that science teachers run inquiry-based instruction using effective teaching strategies and proper evaluation strategies.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.121-127
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• 2021

Objectives : The characteristics of depressive symptoms in patients with cancer is different from those in control group. However, few research has focused on the association between depressive symptoms in cancer patients. The aim of this study was to compare the network structure of depressive symptoms between patients with cancer and normal control. Methods : This study was based on cohort data from Korea National Health and Nutrition Examination Survey in 2016-2018. The Patient health Quetionnaire-9 (PHQ-9) was used to assess depressive symptoms in 599 patients with cancer and 599 age-sex matched controls. We estimated network structure of depressive symptom using Isingfit model. Results : There was no significant difference of each PHQ-9 item score. There were strong associations between symptoms were concentration problem-psychomotor activity, anhedonia-depressed mood, and depressed mood-suicidal ideation in both groups. Strength centrality of worthlessness was significantly higher in patients with cancer. Conclusions : These results suggest that worthless is associated with other depressive symptoms more tightly in patients with cancer. Worthless can serve as important treatment targets for intervention of depression in patients with cancer.

• The Journal of the Korea Contents Association
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• v.21 no.7
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• pp.59-70
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• 2021

This paper studies and analyzes the effect of illustrations in picture books on time representation with fictional picture books as the study scope. In this paper, the time type of picture books can be divided into time point, timeline and time rhythm, referring to case analysis from time symbolic elements, picture layout and picture sequence respectively. First of all, time symbolic elements are referred to the time point and time rhythm. The materialized time symbolic element is things that can directly represent time and trigger associations with time; the color symbolic element means the color changes in the real world within a certain time; the contrast of light and shadow corresponds to the changes in a day. Fast-moving objects will be presented with dashed or blurred lines, while static, stable and slow objects will be depicted with solid lines. Secondly, the picture layout of illustrations in picture books is suitable for representing the content of the timeline and describing the sequence or causality of events. Finally, the picture sequence can represent the timeline, time rhythm and "synchronicity". It will make use of visual logic to win readers' trust in time information expressed in pictures, and then follow and connect viewpoints on the basis of adapting to reading habits. The essence of time representation in picture books is to express time by space, and use different combinations of elements in space and visual guidance to convey time information.

• Journal of Breast Cancer
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• v.21 no.4
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• pp.406-414
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• 2018

Purpose: T-cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) is an emerging immune response molecule related to T-cell anergy. There has been tremendous interest in breast cancer targeting immune checkpoint molecules, especially in the triple-negative breast cancer (TNBC). This study was designed to investigate TIM-3 expression on tumor infiltrating lymphocytes (TILs), its relationships with clinicopathological parameters and expression of programmed death receptor 1 (PD-1)/programmed death receptor ligand 1 (PD-L1), and its prognostic role. Methods: Immunohistochemistry on tissue microarray blocks produced from 109 samples of invasive ductal carcinoma type TNBC was performed with antibodies toward TIM-3, PD-1, PD-L1 and breast cancer-related molecular markers. Associations between their expression and clinicopathological parameters as well as survival analyses were performed. Results: TIM-3 was expressed in TILs from all 109 TNBCs, consisting of 17 cases (<5%), 31 cases (6%-25%), 48 cases (26%-50%), and 13 cases (>51%). High TIM-3 was significantly correlated with younger patients (p=0.0101), high TILs (p=0.0029), high tumor stage (p=0.0018), high PD-1 (p=0.0001) and high PD-L1 (p=0.0019), and tended to be associated with higher histologic grade, absence of extensive in situ components and microcalcification. High TIM-3 expression was significantly associated with a combinational immunophenotype group of high PD-L1 and high PD-1 (p<0.0001). High TIM-3 demonstrated a significantly better disease-free survival (DFS) (p<0.0001) and longer overall survival (OS) (p=0.0001), together with high TILs and high PD-1. In univariate survival analysis, high TIM-3 showed reduced relapse risk (p<0.0001) and longer OS (p=0.0003), together with high PD-1 expression. In multivariate analysis, high TIM-3 was statistically significant in predicting prognosis, showing better DFS (hazard ratio [HR], 0.0994; 95% confidence interval [CI], 0.0296-0.3337; p=0.0002) and longer OS (HR, 0.1109; 95% CI, 0.0314-0.3912; p=0.0006). Conclusion: In this study, we demonstrate that TIM-3 expression is an independent positive prognostic factor in TNBC, despite its association with poor clinical and pathologic features.

• Journal of Veterinary Clinics
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• v.35 no.6
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• pp.258-265
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• 2018

We aimed to identify the relationships between puerperal metritis (PM) and serum metabolites, uterine health, milk yield, and reproductive performance in dairy cows. Blood samples from 150 Holstein dairy cows were collected just after calving, and at 1, 2, and 4 weeks postpartum to measure serum concentrations of ${\beta}$-hydroxybutyrate (BHBA), urea nitrogen, total cholesterol (TCH), albumin, aspartate aminotransferase (AST), calcium, and magnesium. PM was diagnosed by the presence of fever (${\geq}39.5^{\circ}C$) and a watery, fetid uterine discharge during the first 14 days after calving. Cows were divided into two groups on the basis of the presence or absence of the disease: a control group (n = 83) and a PM group (n = 67). The cows diagnosed with PM were subcutaneously administered with 2.2 mg/kg ceftiofur for 3-5 days. The serum concentrations of BHBA tended to be higher (P = 0.06) and AST was higher (P < 0.05) in the PM group than in the control group 1 week after calving, whereas serum concentrations of urea nitrogen, TCH, albumin, calcium, and magnesium were lower (P < 0.05-0.0001) after calving in the PM group than in the control group. The probability of clinical endometritis was higher (odds ratio = 5.40, P < 0.001) in the PM group than in the control group. Moreover, the proportion of neutrophils in the uterus was also higher in the PM group than in the control group 4, 6, and 8 weeks after calving (P < 0.001). The mean milk yield 1 and 2 months after calving was lower (P = 0.05) in the PM group than in the control group. The hazard of pregnancy by 180 days after calving tended to be lower (hazard ratio = 0.60, P = 0.07) in the PM group than in the control group, which led to an extended mean interval between calving and pregnancy (19 days) in the PM group (P < 0.01). In conclusion, PM is associated with higher postpartum concentrations of BHBA and AST, and lower concentrations of urea nitrogen, TCH, albumin, calcium, and magnesium. Moreover, PM is associated with subsequent poor uterine health, lower milk yield, and poorer reproductive performance in dairy cows.

• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.7
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• pp.945-952
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• 2018

Recently, bass fishing has become a marine leisure sport in Korea. There are 4 major fishing associations in Korea, and each association holds 10-15 tournaments each year. However, supply of 17 ft bass boats, which are preferred in leagues, depends 100 % on imports. In this study, we have derived the main specifications to develop the initial hull forms of a 18.5ft bass boat through statistical analysis based on mothership data. In addition, CFD numerical analysis was carried out according to deadrise angle and longitudinal center of gravity, which strongly influenced the resistance and planing performance. For numerical analysis, design speed was set to $Fn=3.284 (Re=9.858{\times}10^7)$, the deadrise angle was set from 12 to $20^{\circ}$, and the longitudinal center of gravity was set in the range of 0 to $8%L_{wL}$ from the center of buoyancy to the stern. Based on the numerical results, we first set the range of these factors by resistance performance and immersion keel length. Furthermore, using a correlation graph of Savitsky's Drag-Lift ratio, we derived the deadrise angle ($14-16^{\circ}$) and longitudinal center of gravity ($4-6%L_{wL}$).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.66-74
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• 2019

The purpose of this study was to analyze work complexity, critical thinking disposition, and the degree of intuition for nurse practitioners and determine the associations among the variables. 150 nurses at hospitals and general hospitals in D City participated in this study and data collection was performed from June 15 to July 8, 2017. The data were processed by using SPSS WIN 24.0 to estimate the mean, standard deviation and Pearson's correlation coefficient and perform one-way ANOVA. They scored $2.33{\pm}.45$ for work complexity, $3.58{\pm}.36$ for critical thinking disposition, and $2.69{\pm}.52$ for intuition. Work complexity differed significantly by age (F=4.55, p=.012), education (F=11.61, p=<.001), department (F=26.69, p=<.001), and clinical career (F=4.30, p=.006) among their general characteristics. Critical thinking disposition differed significantly by education (F=5.25, p=.006) and position (F=5.35, p=.006) and differed statistically insignificantly by intuition. Work complexity was positively correlated with critical thinking disposition (r=.323, p=<.001) and intuition (r=.201, p=.013) and no significant correlation was found between critical thinking disposition and intuition (r=.033, p=.685). On the basis of these results, it is necessary to develop education and programs that can allow nurses who regard nursing work as complex to improve their critical thinking disposition and intuition.