• The Journal of the Korea Contents Association
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• v.10 no.2
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• pp.286-294
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• 2010

This study was performed to identify the cerebral network associated with sensation through the tickling stimulation, which is distinctive from the rest of other networks processing normal stimulation and to investigate the difference of laughing mechanism which is closely related to tickling using functional MRI(fMRI). A 16 healthy volunteers (mean age: 28.9) on a 3.0T MR scanner during two sensation conditions. Counterbalanced stimulus were presented across the participants, and the stimulation was used block design. Acquired data was analyzed by the statistical parametric mapping (SPM 99). Subject and group analysis was performed. Individual analysis showed the activation of somatic sensation area in both tasks and the tickling sensation test showed more activated area in the Wernicke's area(BA40) compared to the normal sensation. The group analysis result shows that under normal stimulations, both sides of somatosensory cortices(BA 1,2 and 3) were activated and under tickling stimulation, not only the cortices but also those huge activation on thalamus, cingulate gyrus and insular lobe were detected. When the tickling was stopped, significant activations were shown in right cingulate gyrus, left MFG area and left insular lobe. A cerebral area responsible for recognizing tickling sensation was examined and the primitive stimulation such as tickling is much closely related to laugh, which is an important factor for various social activities.

• Science of Emotion and Sensibility
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• v.16 no.1
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• pp.53-64
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• 2013

Folksonomies have potential problems caused by synonyms, tagging level, neologisms and so forth when retrieving music by tags. These problems can be tackled by introducing the mood intensity (Arousal and Valence value) of music as its internal tag. That is, if moods of music pieces and their mood tags are all represented internally by numeric values, A (Arousal) value and V (Valence) value, and they are retrieved by these values, then music pieces having similar mood with the mood tag of a query can be retrieved based on the similarity of their AV values though their tags are not exactly matched with the query. As a prerequisite study, in this paper, we propose the mapping table defining the relation between AV values and folksonomy tags. For analysis of the association between AV values and tags, ANOVA tests are performed on the test data collected from the well known music retrieval site last.fm. The results show that the P values for A values and V values are 0.0, which means the null hypotheses could be rejected and the alternative hypotheses could be adopted. Consequently, it is verified that the distribution of AV values depends on folksonomy tags.

• Genomics & Informatics
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• v.6 no.1
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• pp.18-28
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• 2008

Single nucleotide polymorphisms (SNPs) are the most abundant forms of human genetic variations and resources for mapping complex genetic traits and disease association studies. We have constructed a linkage disequilibrium (LD) map of chromosome 22 in Korean samples and compared it with those of other populations, including Yorubans in Ibadan, Nigeria (YRI), Centre d'Etude du Polymorphisme Humain (CEPH) reference families (CEU), Japanese in Tokyo (JPT) and Han Chinese in Beijing (CHB) in the HapMap database. We genotyped 4681 of 111,448 publicly available SNPs in 90 unrelated Koreans. Among genotyped SNPs, 4167 were polymorphic. Three hundred and five LD blocks were constructed to make up 18.6% (6.4 of 34.5 Mb) of chromosome 22 with 757 tagSNPs and 815 haplotypes (frequency $\geq$ 5.0%). Of 3430 common SNPs genotyped in all five populations, 514 were monomorphic in Koreans. The CHB + JPT samples have more than a 72% overlap with the monomorphic SNPs in Koreans, while the CEU + YRI samples have less than a 38% overlap. The patterns of hot spots and LD blocks were dispersed throughout chromosome 22, with some common blocks among populations, highly concordant between the three Asian samples. Analysis of the distribution of chimpanzee-derived allele frequency (DAF), a measure of genetic differentiation, Fst levels, and allele frequency difference (AFD) among Koreans and the HapMap samples showed a strong correlation between the Asians, while the CEU and YRI samples showed a very weak correlation with Korean samples. Relative distance as a quantitative measurement based upon DAF, Fst, and AFD indicated that all three Asian samples are very proximate, while CEU and YRI are significantly remote from the Asian samples. Comparative genome-wide LD studies provide useful information on the association studies of complex diseases.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.11
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• pp.1544-1550
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• 2008

The retinoids (vitamin A and its derivatives) play a critical role in vision, growth, reproduction, cell differentiation and embryonic development. Using the IMpRH panel, porcine cellular retinol binding protein genes 5 and 7 (RBP5 and RBP7) were assigned to porcine chromosomes 5 and 6, respectively. The complete coding sequences (CDS) of the RBP5 and RBP7 genes were amplified using the reverse transcriptase polymerase chain reaction (RT-PCR) method, and the deduced amino acid sequences of both genes were compared to human corresponding proteins. The mRNA distributions of the two genes in adult Wuzhishan pig tissues (lung, skeletal muscle, spleen, heart, stomach, large intestine, lymph node, small intestine, liver, brain, kidney and fat) were examined. A total of nine single nucleotide polymorphisms (SNPs) were identified in two genes. Three of these SNPs were analyzed using the polymerase chain reaction-restriction-fragment length polymorphism (PCR-RFLP) method in Laiwu, Wuzhishan, Guizhou, Bama, Tongcheng, Yorkshire and Landrace pig breeds. Association analysis of genotypes of these SNP loci with economic traits was done in our experimental populations. Significant associations of different genotypes of $RBP5-A/G^{63}$, $RBP5-A/G^{517}$ and $RPB5-T/C^{intron1-90}$ loci with traits including maximum carcass length (LM), minimum carcass length (LN), marbling score (MS), back fat thickness at shoulder (SBF), meat color score (MCS) and hematocrit (HCT) were detected. These SNPs may be useful as genetic markers in genetic improvement for porcine production.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.476-476
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• 2011

베트남은 자연재해로 인해 매년 평균 750명 이상의 사망자가 발생하고 있으며, 경제적인 피해 또한 한해 GDP의 1.5%에 달하고 있다. 저먼워치(Germanwatch)의 2010년 세계기후위험지수(Global Climate Risk Index, GCRI)의 전 지구적 기후재난에 관한 국가별 순위 조사에서 베트남은 4위에 기록되었다. 베트남의 자연재해는 상당 비중이 풍수해에 집중 되어 전체 재해의 86%를 차지하고 있고, 이는 대부분 해안 지대와 강 유역의 홍수 및 범람에서 비롯된 것이다. 베트남 전체인구의 약 70%가 상습적 홍수와 범람 발생 지역인 해안가에 거주하고 있어 재난에 예방 및 복구 관리에 대한 국가 차원의 방안이 시급한 실정이다. 본 연구에서는 과거 30년간의 풍수해 관련 재해에 대한 기록상 추이를 통해 공간적으로 재난에 취약한 지역적 분포를 살펴보고, 그 지역의 지리적 특성을 분석하여 재해에 관한 종합적 고찰을 하였다. 벨기에 루뱅대학 부설 재난역학연구센터(Centre for Research on the Epidemiology of Disasters, CRED)의 EM-DAT를 이용하여 과거 기록상의 개괄적인 재해양상에 관한 추이를 살펴본 결과 대부분의 재난은 풍수해에 집중이 되어 있음을 분석하였고, 베트남 풍수해조정기관인 홍수및폭풍조정중앙위원회(Central Committee for Flood and Storm Control, CCFSC)의 최근 30년간 풍수해에 관련된 통계 자료를 정리하여 상습적 재난 피해지역을 지도상에 표시하였다. 이 때 지구지도제작운영위원회(International Steering Committee for Global Mapping, ISCGM)의 D_WGS_1984 Datum을 바탕으로 한 베트남 shape file을 이용하여 풍수해에 따른 인명피해, 경제적 손실, 발생횟수 등에 관한 사항을 일반화 시켜 재난 취약지역을 지리적으로 분석하였다. Thanh hoa, Quang nam, Binh Dinn, Camau성이 풍수해와 관련된 재난에 취약하게 노출되어 있음을 도출하였다. 재난에 상대적으로 취약한 이들 지역에 대한 현재의 재난 관리는 어떻게 이루어지고 있는지에 관해 현재의 풍수해관리 사업단의 조직적 구조와 그 기능 및 역할을 살펴보고, 국제적 원조 사례를 분석하여 상습적으로 재난의 위험 지역에 대한 지속적인 관리와 복구를 어떻게 이루어 나갈 것인지에 대한 방안 및 제언에 관하여 논의하고자 한다. 베트남의 재난 관리에 관한 지리적인 종합 분석은 기존 양상의 재해에 대한 방안을 구축하는 데 대한 제언뿐만 아니라 기후변화와 관련된 재난을 예측하고 관리 방안을 설정하는 데 기초 자료를 제공할 수 있을 것이다.

• Journal of Korea Water Resources Association
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• v.51 no.6
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• pp.481-490
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• 2018

Recently, the spatiotemporal patterns of flood disasters have become more complex and unpredictable due to climate change. Flood hazard map including information on flood risk level has been widely used as an unstructured measure against flooding damages. In order to product a high-precision flood hazard map by combination of hydrologic and hydraulic modeling, huge digital information such as topography, geology, climate, landuse and various database related to social economic are required. However, in some areas, especially in developing countries, flood hazard mapping is difficult or impossible and its accuracy is insufficient because such data is lacking or inaccessible. Therefore, this study suggests a method to delineate large scale flood-prone area based on topographic factors produced by linear binary classifier and ROC (Receiver Operation Characteristics) using globally-available geographic data such as ASTER or SRTM. We applied the proposed methodology to five different countries: North Korea Bangladesh, Indonesia, Thailand and Myanmar. The results show that model performances on flood area detection ranges from 38% (Bangladesh) to 78% (Thailand). The flood-prone area detection based on the topographical factors has a great advantage in order to easily distinguish the large-scale inundation-potent area using only digital elevation model (DEM) for ungauged watersheds.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.12
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• pp.543-548
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• 2017

In recent years, the importance of the safety of medical device software has been emphasized because of the function and role of the software among components of the medical device, and because the operation of the medical device software is directly related to the life and safety of the user. To this end, various standards have been set up that provide activities that can effectively ensure the safety of medical devices and provide their respective requirements. The activities that standards provide to ensure the safety of medical device software are largely divided into the development life cycle of medical device software and the risk management process. These two activities should be concurrent with the development process, but there is a limitation that the risk management requirements to be performed at each stage of the medical device software development life cycle are not classified. As a result, developers must analyze the association of standards directly to develop risk management activities during the development of medical devices. Therefore, in this paper, we analyze the relationship between medical device software development life cycle and risk management process, and extract risk management requirement items. It enables efficient and systematic risk management during the development of medical device software by mapping the extracted risk management requirement items to the development life cycle based on the analyzed associations.

• Journal of the Korean Association of Geographic Information Studies
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• v.11 no.4
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• pp.101-111
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• 2008

To provide more natural elements in the harsh urban environment, 'planting trees as urban forests' has been emphasized as having an important role, and trees are expected to be as functional as the trees under more natural conditions in rural areas, and provide people with benefits. To do this, urban forest policies needed a better idea of planting methods and management of trees through the theory of landscape ecology, and also the feedback system according to the evaluation and assessment of urban forests. In this case study, a new principle and assessment indices for the evaluation are applied for the 4 urban forests in two Korean metropolitan cities, Daejeon and Ulsan. The evaluation of Korean urban forest-function as biotope and the assessment for the classification of biotope diversity types are carried out. The AUEM(Adding Up Estimation Matrix) is applied for the analysis of urban forests. Unlikely previous researches on the other Korean metropolitan cities, the size of urban forest has less influence on the vegetation diversity. The most frequent biotope grade is the 3rd grade at Namseon park and Mt. Hamwol, while Mt. Bomun and Mt. Yeompo show the 4th grade. The grades of forest-function as biotope are from 3rd to 5th in which lower than average in forest-function grades. This means that the 4 sites are still not-matured forests and less-functional forests as the urban biotope.

• Korean Journal of Poultry Science
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• v.42 no.4
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• pp.315-325
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• 2015

Recently, livestock breeding is more focused on the meat quality rather than meat quantity, mainly due to the improvement of consumers' income. Among the meat quality traits, meat color is one of very important traits because meat color is the first selection criterion from the consumers in the market. Most of the economically important traits have continuous variations and these are called quantitative traits. the genomic locations affecting these traits are called quantitative trait locus (QTL), which is mostly controlled by many genes having small effects. In this study, the recent QTL and candidate gene studies were reviewed in order to meet the consumers' demand for the future market. In the chicken QTL database, three traits are related with meat colors, namely breast color (Bco), meat color (Mco), drip loss (DL) and pH. The identified number of QTLs is 33 from 13 chromosomal regions. In these QTL regions, 14 candidate genes were identified; Eight for meat color (APP, BCMO1, COL1A2, FTO, KPNA2, PSMD12, G0S2, FTSJ3), two for drip loss (AGRP, FTO) and four for pH (GALNT1, PCDH19, DIAPH1, SPP2). These QTLs and candidate genes need to be confirmed and fine mapping is ultimately needed for identification of causative variations. The recently developed chicken resource population using Korean native chicken can be used for the improvement of meat quality traits, which increase the value that needed in the chicken industry.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.291-295
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• 2007

강수진단모형을 이용하여 저수지 이수운영을 위한 실시간 유량예측기법을 개발하였다. 강수진단모형은 현재 기상청 현업에서 수행중인 강우수치예보를 기반으로 상세 지역의 지형 효과에 의한 강수를 예측하는 정량강수예측모형(QPM; Quantitative Precipitation Model)으로서 부경대학교 환경대기과학과에서 개발된 모형이다. QPM은 중규모 예측 모형으로부터 계산된 수평 바람, 고도, 기온, 강우 강도, 그리고 상대습도 등의 예측 자료를 이용하고, 소규모 상세지형 효과를 고려함으로써 중규모 예측 모형에서 생산된 강수량 예측 값을 상세 지역의 지형을 고려한 강수량 예측 값으로 재구성하여 결과적으로 3km 간격의 상세지역 강우산출과 지형에 따른 강수량의 분포 파악이 용이할 뿐만 아니라 계산 효율성을 개선된 모형이다. QPM 검증을 위하여 기상학적 평가와 수문학적 평가를 수행하였다. 호우 사례별 일강수량의 시공간 분포로 부터, QPM을 활용한 시스템에 의한 예측결과가 원시자료 RDAPS 보다 고해상도의 예측 및 지형효과의 반영도가 높았으며, AWS의 관측자료와 비교하여 보다 높은 예측성을 보여 주었다. 대상기간인 2006년 1월 1일부터 6월 20일까지 관측강우는 총 391.5mm 였으며 RQPM은 실적강우에 비하여 119.5mm 정도 과소산정하고 있으나 분위사상과정을 거치게 되면 351.7mm로서 실적강우에 불과 10.2% 못미치고 있다. 이는 고무적인 결과로 볼 수 있으며 현업에서의 활용성이 기대되는 수준이라 볼 수 있다. 강우-유출모의를 위한 QPM신뢰도를 높이기 위하여 분위사상법(Quantile Mapping)을 이용하여 QPM모의에 존재할 수 있는 계통오차에 대한 추가적인 보정을 수행하였다. 수문학적 평가를 위하여는 장기연속유출모형인 SSARR모형을 기반으로 개발된 RRFS(Rainfall-Runoff Forecast System)을 이용하여 2006년 1월${\sim}$9월까지의 용담댐 유입량에 대하여 모의예측결과와 관측유입량 비교를 통한 검증을 수행하였다. 위 기간중 예측유입량의 RMSE(Root Mean Squared Error), COE(Sutcliffe Coefficient of Efficiency), MAE(Mean Absolute Error), $R^2$값은 각각 7.50, 0.68, 2.59, 0.69 값을 보이고 있다. 본 연구에서는 QPM에 의한 예측성의 향상 및 구축된 시스템에 의한 일강수량의 장기예측 가능성을 확인하였고, 향후 시스템을 현업에 활용하기 위해서 생산된 예측자료의 보다 장기적인 검증을 통한 시스템의 안정화가 필요할 것으로 사료된다.