• 한국화재소방학회논문지
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• 제33권4호
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• pp.140-151
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• 2019

본 연구에서는 소방관들이 화재현장에서 복귀 후 소방청사 내에서 2차적으로 노출된 화학적 유해물질의 실내공기질을 평가하였다. 서울시에 소재한 4개 소방서를 선정하였고, 그 중 2개 소방서는 실제 화재현장에서 소방활동 종료 귀소 후에, 다른 2개 소방서는 대조군으로 설정하여 출동과 상관없이 평소 수준의 실내공기질을 측정하였다. 소방안전지도 전산시스템을 이용하여 서울시에서 발생하는 모든 화재사고에 대하여 24시간 모니터링을 실시하였고 중급규모 이상의 사고에서 실험군이 출동하게 되는 경우 귀소 후 바로 실내공기질을 측정하였다. 11개 유해물질 항목(미세먼지, 포름알데히드, 휘발성유기화합물, PAH, VCM, 산류, 석면, CO, CO₂, NO₂, O₃)을 공정시험법에 따라 측정하였다. 유해물질 11종 중 3종이 국내·외 기준을 초과하였고 1종은 국외기준에 육박하는 것으로 확인되었다. 특히 총휘발성 유기화합물, 이산화탄소, 황산은 각 2.5배, 2.2배, 1.1배가 환경부 및 고용노동부 기준보다 높았다. 또한, 포름알데히드와 황산의 경우, 실험군보다 대조군에서 더 높게 측정되었다. 본 연구결과는 서울특별시 소방청사 내 실내공기질 개선 정책에 활용될 수 있을 것이다.

• Journal of the Optical Society of Korea
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• 제20권5호
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• pp.607-613
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• 2016

The pleura is known as an end target organ of exposure to toxic environmental materials such as fine particulate matter and asbestos. Moreover, long-term exposure to hazardous materials can eventually lead to fatal lung disease such as diffuse pleural fibrosis or mesothelioma. Chest computed tomography (CT) and ultrasound are gold standard imaging modalities for detection of advanced pleural disease. However, a diagnostic tool for early detection of pleural reaction has not been developed yet due to difficulties in imaging ultra-fine structure of the pleura. Optical coherence tomography (OCT), which provides cross-sectional images of micro tissue structures at a resolution of 2-10 μm, can image the mesothelium with a thickness of ~100 μm and therefore enables investigation of the early pleural reaction. In this study, we induced the early pleural reaction according to a time sequence after pleurodesis using talc, which has been widely used in the clinical field. The pleural reaction in talc grouped according to the time sequence (1st, 2nd, 4th weeks) showed a significant thickening (average thickness: 45 ± 7.5 μm, 80 ± 10.7 μm, 90 ± 12.5 μm), while the pleural reaction in sham and normal groups showed pleural change from normal to minimal thickening (average thickness: 16 ± 5.5 μm, 17 ± 4.5 μm, 15 ± 6.5 μm, and 12 ± 7.5 μm, 13 ± 2.5 μm, 12 ± 3.5 μm). The measurement of pleural reaction by pathologic examinations was well-matched with the measurement by OCT images. This is the first study for measuring the thickness of pleural reactions using a biophotonic modality such as OCT. Our results showed that OCT can be useful for evaluating the early pleural reaction.

• Tuberculosis and Respiratory Diseases
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• 제38권2호
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• pp.135-142
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• 1991

We reviewed 15 cases of mesothelioma of the pleura, of which three cases were localized benign form and 12 cases were malignant diffuse form. The tumors were distributed equally in both sexes, and occured most commonly in fifth to seventh decades. The history of exposure to asbestos was present in only one case. The chief complaints were mainly chest pain and dyspnea. Associated symptoms were cough, sputum, hemoptysis, weight loss, anorexia, chill. On physical examination, unilateral, decreased breathing sound was main feature. The simple chest radiograph showed masses in all localized mesotheliomas (100%) and in 2 diffuse mesotheliomas (17%). 8 cases of diffuse mesotheliomas (67%) showed unilateral pleural effusions. Pleural effusions were mainly bloody (67%), and almost all were exudates. In all localized mesotheliomas, final diagnosis was made by open thoracotomy. In diffuse mesotheliomas, final diagnosis was made by open thoracotomy in 7 cases, chest wall mass biopsy in 2 cases, thoracoscopic biopsy in 1 case, pleural biopsy in 1 case, and pleural biopsy combined with axillary lymph node biopsy in 1 case. Localized mesotheliomas were treated by simple excision with good prognosis. In diffuse mesotheliomas, surgical treatment (pleuropneumonectomy, pleurectomy), chemotherapy, or radiotherapy, alone or in combination, were used with dismal prognosis. The prognostic factors were not found due to the small number of cases, incomplete follow up, and early drop out.