• Title/Summary/Keyword: aryl ketoesters

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Improved One-pot Regioselective Synthesis of 3,7-Diarylpyrazolo[1,5-α]pyrimidines and Their CB1R Activity (3,7-Diarylpyrazolo[1,5-α]pyrimidines의 개선된 One-pot Regioselective 합성과 CB1R 활성)

  • Hong, Yong Deog;Byoun, Kyoung Hee;Park, Miyoung;Park, Jun Seong;Shin, Song Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.2
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    • pp.143-150
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    • 2015

  • This study demonstrates an effective one-pot regioselective synthesis of 3,7-diarylpyrazolo [1,5-${\alpha}$]pyrimidines. Moreover, the derivatives obtained were effective CB1R antagonists. These pyrazolo [1,5-${\alpha}$]pyrimidines with diaryl groups at the 3,7-positions are potential pharmacophores for CB1R candidates.

  • https://doi.org/10.15230/SCSK.2015.41.2.143 인용 PDF KSCI